Click here to switch to the map view.

The map label for this gene is 116622861

Identifier: 116622861

GI number: 116622861

Start: 4780702

End: 4781658

Strand: Direct

Name: 116622861

Synonym: Acid_3762

Alternate gene names: NA

Gene position: 4780702-4781658 (Clockwise)

Preceding gene: 116622860

Following gene: 116622862

Centisome position: 47.97

GC content: 64.16

Gene sequence:

>957_bases
GTGCCGGTCACAGCGGTCGCATTCTCGCCGGATGGCAAACTGGTGGTCTCGGGCGGGTATAAAGAACTGCTGCTCTGGGA
TCCTTCGACCGGAAGGTTGGTTCGGAAGATTGGGAAACTGTCGGGGCAGGTGCGCGCCATCGCGTTCGGAGCGGACTCGA
ACTCGATCGCGGTGGCGGACGGCGTTCCGGGGCGTGCGGGATCGGTCGTGCAGGTTGATCTCCAAATCGGTGCGATCACC
GCGATCCAGCAGGCGAAGGACGAAATGCTCGCCGTGGCATTCTCGGCCGACGGCAAGTTACTCGCTACCGGCGGCACCGA
TTCGATCGTTCGCATCTATGCGACCGGGACCAACGCAGCGCCCATCGAGCTCAAGGGCCACACAGGCTGGATCTCAGGCG
TCGCCTTCTCGCCCGATGGCAAACTCTTTGCGTCCGGCAGTGCCGATAAAACAGTCCGCGTGTGGAAGACGGACACGTGG
AAGGAAGTTTTCCAATTGCCGGCACAGATCACCGAGCCGGTAAGCGCCGTGGCCTTCGCGAACGAAGGCGACCTGCTCGC
CTTCGCCACCGGCGGCCCCGACGAACGCGCGATCCGCATCTGGCGTACGCAGGGCGCCTTCACCGAGCTGGACTCCACGC
GTCCCGGGCAGCGCAATGGCCTGATGCAGACGCGTCCCATCGATACAGGAGCGTGCCTCCCGCTCGCTGTGACTTTCAGC
AAGGCGCAGCCGCACTCGCGCATCGTCGTGGGGTGTAGCGATAAGACGGTACGTTTCATCGCGCCGGGTGGCAATACGAT
CGCGACCGGCACGGGCCACGGCGATTGGGTCTACACGGTGGCGTCGAGCCCCGATGGAACGCGCATCGCCTCGGCCGGCG
CAGATGGCACCGTGAAAATCTGGACTCCCGCAGGCAAGCTGCTGTTCACGCTCAAGGAAGGAAGCACCCAGCCATGA

Upstream 100 bases:

>100_bases
GGACGTTTGCGCCCTGCGAGCAAGCAAGAGCAGTGTAATACAAGTTGCGGGTCGTTGTGTTGCCTTCTTCATCACGCTTG
CCGCGTTCGCCGCGCCGTCC

Downstream 100 bases:

>100_bases
AGCGGCTGTCCATTGTCTTCGTGTTGGCAATTACGGTCCTCGCGCAGCCAGCGAAAAAGGCGCCCGCTCCGCAACTGATC
GAACCGGTGCAGCCCGTGCT

Product: WD-40 repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPVTAVAFSPDGKLVVSGGYKELLLWDPSTGRLVRKIGKLSGQVRAIAFGADSNSIAVADGVPGRAGSVVQVDLQIGAIT
AIQQAKDEMLAVAFSADGKLLATGGTDSIVRIYATGTNAAPIELKGHTGWISGVAFSPDGKLFASGSADKTVRVWKTDTW
KEVFQLPAQITEPVSAVAFANEGDLLAFATGGPDERAIRIWRTQGAFTELDSTRPGQRNGLMQTRPIDTGACLPLAVTFS
KAQPHSRIVVGCSDKTVRFIAPGGNTIATGTGHGDWVYTVASSPDGTRIASAGADGTVKIWTPAGKLLFTLKEGSTQP

Sequences:

>Translated_318_residues
MPVTAVAFSPDGKLVVSGGYKELLLWDPSTGRLVRKIGKLSGQVRAIAFGADSNSIAVADGVPGRAGSVVQVDLQIGAIT
AIQQAKDEMLAVAFSADGKLLATGGTDSIVRIYATGTNAAPIELKGHTGWISGVAFSPDGKLFASGSADKTVRVWKTDTW
KEVFQLPAQITEPVSAVAFANEGDLLAFATGGPDERAIRIWRTQGAFTELDSTRPGQRNGLMQTRPIDTGACLPLAVTFS
KAQPHSRIVVGCSDKTVRFIAPGGNTIATGTGHGDWVYTVASSPDGTRIASAGADGTVKIWTPAGKLLFTLKEGSTQP
>Mature_317_residues
PVTAVAFSPDGKLVVSGGYKELLLWDPSTGRLVRKIGKLSGQVRAIAFGADSNSIAVADGVPGRAGSVVQVDLQIGAITA
IQQAKDEMLAVAFSADGKLLATGGTDSIVRIYATGTNAAPIELKGHTGWISGVAFSPDGKLFASGSADKTVRVWKTDTWK
EVFQLPAQITEPVSAVAFANEGDLLAFATGGPDERAIRIWRTQGAFTELDSTRPGQRNGLMQTRPIDTGACLPLAVTFSK
AQPHSRIVVGCSDKTVRFIAPGGNTIATGTGHGDWVYTVASSPDGTRIASAGADGTVKIWTPAGKLLFTLKEGSTQP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 16 WD repeats [H]

Homologues:

Organism=Homo sapiens, GI239787754, Length=218, Percent_Identity=31.1926605504587, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI239787760, Length=218, Percent_Identity=31.1926605504587, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI26665869, Length=307, Percent_Identity=26.7100977198697, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI32189425, Length=204, Percent_Identity=28.4313725490196, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI113865883, Length=270, Percent_Identity=30.3703703703704, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI16554629, Length=233, Percent_Identity=28.3261802575107, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI16554627, Length=233, Percent_Identity=28.3261802575107, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI239787764, Length=216, Percent_Identity=27.3148148148148, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI102470001, Length=307, Percent_Identity=24.4299674267101, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI21071067, Length=157, Percent_Identity=35.031847133758, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI189571685, Length=175, Percent_Identity=32, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI189571683, Length=175, Percent_Identity=32, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI189571681, Length=175, Percent_Identity=32, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI5174447, Length=213, Percent_Identity=28.6384976525822, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI23199987, Length=237, Percent_Identity=27.0042194092827, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI115298668, Length=220, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI62234461, Length=212, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4557741, Length=184, Percent_Identity=29.8913043478261, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17552164, Length=235, Percent_Identity=28.0851063829787, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17541222, Length=216, Percent_Identity=26.8518518518519, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17568701, Length=218, Percent_Identity=27.5229357798165, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI72001544, Length=248, Percent_Identity=23.3870967741935, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319675, Length=232, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319926, Length=241, Percent_Identity=28.6307053941909, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325435, Length=308, Percent_Identity=23.0519480519481, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17864654, Length=233, Percent_Identity=28.755364806867, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI161077441, Length=227, Percent_Identity=29.0748898678414, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922822, Length=227, Percent_Identity=29.0748898678414, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24652561, Length=229, Percent_Identity=27.9475982532751, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24663767, Length=304, Percent_Identity=25, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45552655, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573462, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573460, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573458, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573456, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137196, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137396, Length=262, Percent_Identity=25.5725190839695, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356075, Length=204, Percent_Identity=28.921568627451, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001646
- InterPro:   IPR020472
- InterPro:   IPR007111
- InterPro:   IPR011047
- InterPro:   IPR015943
- InterPro:   IPR001680
- InterPro:   IPR011046
- InterPro:   IPR019782
- InterPro:   IPR019775
- InterPro:   IPR017986
- InterPro:   IPR019781 [H]

Pfam domain/function: PF00805 Pentapeptide; PF00400 WD40 [H]

EC number: NA

Molecular weight: Translated: 33095; Mature: 32964

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50082 WD_REPEATS_2 ; PS50294 WD_REPEATS_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTAVAFSPDGKLVVSGGYKELLLWDPSTGRLVRKIGKLSGQVRAIAFGADSNSIAVAD
CCEEEEEECCCCCEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEC
GVPGRAGSVVQVDLQIGAITAIQQAKDEMLAVAFSADGKLLATGGTDSIVRIYATGTNAA
CCCCCCCCEEEEEEEECEEHHHHHCCCCEEEEEEECCCCEEEECCCCCEEEEEEECCCCC
PIELKGHTGWISGVAFSPDGKLFASGSADKTVRVWKTDTWKEVFQLPAQITEPVSAVAFA
EEEECCCCCEEEEEEECCCCCEEECCCCCCEEEEEECCCHHHHHHCCHHHCCCCEEEEEC
NEGDLLAFATGGPDERAIRIWRTQGAFTELDSTRPGQRNGLMQTRPIDTGACLPLAVTFS
CCCCEEEEECCCCCCEEEEEEECCCCEEECCCCCCCCCCCCEEECCCCCCCCEEEEEEEC
KAQPHSRIVVGCSDKTVRFIAPGGNTIATGTGHGDWVYTVASSPDGTRIASAGADGTVKI
CCCCCCEEEEEECCCEEEEECCCCCEEEECCCCCCEEEEEECCCCCCEEEECCCCCEEEE
WTPAGKLLFTLKEGSTQP
EECCCEEEEEEECCCCCC
>Mature Secondary Structure 
PVTAVAFSPDGKLVVSGGYKELLLWDPSTGRLVRKIGKLSGQVRAIAFGADSNSIAVAD
CEEEEEECCCCCEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEC
GVPGRAGSVVQVDLQIGAITAIQQAKDEMLAVAFSADGKLLATGGTDSIVRIYATGTNAA
CCCCCCCCEEEEEEEECEEHHHHHCCCCEEEEEEECCCCEEEECCCCCEEEEEEECCCCC
PIELKGHTGWISGVAFSPDGKLFASGSADKTVRVWKTDTWKEVFQLPAQITEPVSAVAFA
EEEECCCCCEEEEEEECCCCCEEECCCCCCEEEEEECCCHHHHHHCCHHHCCCCEEEEEC
NEGDLLAFATGGPDERAIRIWRTQGAFTELDSTRPGQRNGLMQTRPIDTGACLPLAVTFS
CCCCEEEEECCCCCCEEEEEEECCCCEEECCCCCCCCCCCCEEECCCCCCCCEEEEEEEC
KAQPHSRIVVGCSDKTVRFIAPGGNTIATGTGHGDWVYTVASSPDGTRIASAGADGTVKI
CCCCCCEEEEEECCCEEEEECCCCCEEEECCCCCCEEEEEECCCCCCEEEECCCCCEEEE
WTPAGKLLFTLKEGSTQP
EECCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]