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The map label for this gene is csd [H]

Identifier: 116622816

GI number: 116622816

Start: 4720285

End: 4721406

Strand: Reverse

Name: csd [H]

Synonym: Acid_3716

Alternate gene names: 116622816

Gene position: 4721406-4720285 (Counterclockwise)

Preceding gene: 116622819

Following gene: 116622815

Centisome position: 47.38

GC content: 61.23

Gene sequence:

>1122_bases
GTGGCGGAGATACCGCTTTGGCAGCGTTATGCCGATCAATTCCCCGTACGCGACAATCTGCTGTACCTGAATCACGCGGC
CGTCGCGCCGCTGCCGAGGGTGACGGCGGACGCCTTGAAGCATCTGGCCGATGACAGCCTGATGTGGGGAAGCTTGCATT
ATGCCGAGTGGATGGCGGTCTATGACGGGCTGCGGGTGGCTGCGGCTAAGCTGGTGAACGGCGACCCGAGCGAGATCGCG
CTGGTGAAAAACACCTCCGAGGGGATCGCCACGATCGCGATGGGGCTCGACTGGAAGCCGGGCGACCGGATGGTGGGCTT
CAAGGAGGAATTCCCTGCCAATCTGTACCCGTGGAAGCGCCTGGAAGCAAAGGGCGTGGAGGTCACGTGGCTATCCGTAT
ACGACTCGCTGGACCGGATCGACGAGGCCTGCCGCGGAGCGCGGCTGCTCTCGATCAGCTTCGTGCAGTTCCTGAGCGGA
TACCGGGCGCCGATTCAAGAGATTGGTGAGATTTGCCGGCGTAACCGCTGCATTTACTTCGTAGATGCGATCCAGGGTAT
GGGCGCGTTTCCGATCGATGTGCAGGCCTGCCATATAGACGCTCTGGCGGCGGACGGACATAAGTGGATGCTGGGGCCCG
AAGGCTGCGCCATCCTCTACATAAATCGGGAGCTTCAGGATCGCGTGGAACCGGTGGAATTCGGCTGGACGAACGTGGCC
GGATACAACGACTACGGCTCGCGCGACATGGCCCTGCGGCAGGATGCGGGACGATATGAGTGCGGCACGTTAAATACCAT
TGGATGCTTCGGATTGAAGGCATCAATTGAACTGTTGCTGGAAGTGGGGCAAGGAGAAACCGCCCCCGTTATCCAAAACC
TGGGAGACCGGATCGCGGCAGGTGTGCAGGCCAAAGGCTACGAGCTTTTGGGAACGCGGACGCCGGACACGGCAGCTGGG
ATTGTGAGCTTCCGAAAACCCGGGATGGAGGCCACGGACGTGGTGCGGATTCTGCGCGAGCAGAATATCATCGCTGCGCC
ACGGGCCGGGTGGATTCGTACGTCGCCGCACTTCTATATAAGTCCCGCCGAGATCGACCGGCTGATCGACGCGCTGCCGT
GA

Upstream 100 bases:

>100_bases
CAGGAGGCAAACCGACGCGTGCAGGAATCTCATCGCCTACTCCTTATGCCCATTATTTCGTATTGTAGAGGGAATGGGTC
GTGAAATTGTAAATAGTTCT

Downstream 100 bases:

>100_bases
TGGGATGGCTGCGACGGCATCCGCTGGCGGCATTTCTGCCGTTGCAGGCGGCGCTGTACCTGTGGAATCTGGCGCTGCTT
TCGCCGTGGATGGACGAAGC

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MAEIPLWQRYADQFPVRDNLLYLNHAAVAPLPRVTADALKHLADDSLMWGSLHYAEWMAVYDGLRVAAAKLVNGDPSEIA
LVKNTSEGIATIAMGLDWKPGDRMVGFKEEFPANLYPWKRLEAKGVEVTWLSVYDSLDRIDEACRGARLLSISFVQFLSG
YRAPIQEIGEICRRNRCIYFVDAIQGMGAFPIDVQACHIDALAADGHKWMLGPEGCAILYINRELQDRVEPVEFGWTNVA
GYNDYGSRDMALRQDAGRYECGTLNTIGCFGLKASIELLLEVGQGETAPVIQNLGDRIAAGVQAKGYELLGTRTPDTAAG
IVSFRKPGMEATDVVRILREQNIIAAPRAGWIRTSPHFYISPAEIDRLIDALP

Sequences:

>Translated_373_residues
MAEIPLWQRYADQFPVRDNLLYLNHAAVAPLPRVTADALKHLADDSLMWGSLHYAEWMAVYDGLRVAAAKLVNGDPSEIA
LVKNTSEGIATIAMGLDWKPGDRMVGFKEEFPANLYPWKRLEAKGVEVTWLSVYDSLDRIDEACRGARLLSISFVQFLSG
YRAPIQEIGEICRRNRCIYFVDAIQGMGAFPIDVQACHIDALAADGHKWMLGPEGCAILYINRELQDRVEPVEFGWTNVA
GYNDYGSRDMALRQDAGRYECGTLNTIGCFGLKASIELLLEVGQGETAPVIQNLGDRIAAGVQAKGYELLGTRTPDTAAG
IVSFRKPGMEATDVVRILREQNIIAAPRAGWIRTSPHFYISPAEIDRLIDALP
>Mature_372_residues
AEIPLWQRYADQFPVRDNLLYLNHAAVAPLPRVTADALKHLADDSLMWGSLHYAEWMAVYDGLRVAAAKLVNGDPSEIAL
VKNTSEGIATIAMGLDWKPGDRMVGFKEEFPANLYPWKRLEAKGVEVTWLSVYDSLDRIDEACRGARLLSISFVQFLSGY
RAPIQEIGEICRRNRCIYFVDAIQGMGAFPIDVQACHIDALAADGHKWMLGPEGCAILYINRELQDRVEPVEFGWTNVAG
YNDYGSRDMALRQDAGRYECGTLNTIGCFGLKASIELLLEVGQGETAPVIQNLGDRIAAGVQAKGYELLGTRTPDTAAGI
VSFRKPGMEATDVVRILREQNIIAAPRAGWIRTSPHFYISPAEIDRLIDALP

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=230, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1787970, Length=403, Percent_Identity=26.7990074441687, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994898, Length=229, Percent_Identity=31.4410480349345, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789175, Length=395, Percent_Identity=26.3291139240506, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25143064, Length=231, Percent_Identity=29.8701298701299, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319831, Length=335, Percent_Identity=26.2686567164179, Blast_Score=93, Evalue=8e-20,
Organism=Drosophila melanogaster, GI20129463, Length=275, Percent_Identity=29.4545454545455, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41289; Mature: 41157

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIPLWQRYADQFPVRDNLLYLNHAAVAPLPRVTADALKHLADDSLMWGSLHYAEWMAV
CCCCCHHHHHHHCCCCCCCEEEEECHHHCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHH
YDGLRVAAAKLVNGDPSEIALVKNTSEGIATIAMGLDWKPGDRMVGFKEEFPANLYPWKR
HHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCHH
LEAKGVEVTWLSVYDSLDRIDEACRGARLLSISFVQFLSGYRAPIQEIGEICRRNRCIYF
HCCCCCEEEEHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCHHHHHHHHHHCCCCEEE
VDAIQGMGAFPIDVQACHIDALAADGHKWMLGPEGCAILYINRELQDRVEPVEFGWTNVA
EEHHCCCCCCCCEEEEEEEEEEECCCCEEEECCCCEEEEEECCHHHHCCCCCCCCCCCCC
GYNDYGSRDMALRQDAGRYECGTLNTIGCFGLKASIELLLEVGQGETAPVIQNLGDRIAA
CCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHC
GVQAKGYELLGTRTPDTAAGIVSFRKPGMEATDVVRILREQNIIAAPRAGWIRTSPHFYI
CCCCCCEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCEEECCCCCCEECCCCEEE
SPAEIDRLIDALP
CHHHHHHHHHCCC
>Mature Secondary Structure 
AEIPLWQRYADQFPVRDNLLYLNHAAVAPLPRVTADALKHLADDSLMWGSLHYAEWMAV
CCCCHHHHHHHCCCCCCCEEEEECHHHCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHH
YDGLRVAAAKLVNGDPSEIALVKNTSEGIATIAMGLDWKPGDRMVGFKEEFPANLYPWKR
HHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCHH
LEAKGVEVTWLSVYDSLDRIDEACRGARLLSISFVQFLSGYRAPIQEIGEICRRNRCIYF
HCCCCCEEEEHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCHHHHHHHHHHCCCCEEE
VDAIQGMGAFPIDVQACHIDALAADGHKWMLGPEGCAILYINRELQDRVEPVEFGWTNVA
EEHHCCCCCCCCEEEEEEEEEEECCCCEEEECCCCEEEEEECCHHHHCCCCCCCCCCCCC
GYNDYGSRDMALRQDAGRYECGTLNTIGCFGLKASIELLLEVGQGETAPVIQNLGDRIAA
CCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHC
GVQAKGYELLGTRTPDTAAGIVSFRKPGMEATDVVRILREQNIIAAPRAGWIRTSPHFYI
CCCCCCEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCEEECCCCCCEECCCCEEE
SPAEIDRLIDALP
CHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]