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The map label for this gene is 116622726

Identifier: 116622726

GI number: 116622726

Start: 4588169

End: 4589812

Strand: Reverse

Name: 116622726

Synonym: Acid_3625

Alternate gene names: NA

Gene position: 4589812-4588169 (Counterclockwise)

Preceding gene: 116622727

Following gene: 116622722

Centisome position: 46.06

GC content: 64.36

Gene sequence:

>1644_bases
ATGAGCACAGCAATGAGAACGCCCCAGAAAGTACAGAGCCTGCGCACACACGACATCGACGCCGGCGAAAAGACGGCCGG
TTCGCAGAGTCATCTGGCGCGGGCGGTCACGCTCCATCTCGCCGGAAGACGGGAGGAGGCGCTCAAACAGCTTCAGCGGG
CGATTGCCGCGAACGAGGCGTCGGCCGAAATCTACCGCGCCATGGGTCATATTCAGTTCGAGCTGGGCAGCTTCGACGAG
GCGGCCAAAAGCTACCGGATTCTGGTGCAGGTGAAGCCGCAGTACTCCATGGGCTGGTTCAACCTGGCCGTGTGCCTGGA
GCGCGCGGGAGTCTGGGAAGACGCCGCGCAAAGCTTCCACCGCGCCGCCACGCTGGAACCCGGCTACCTGGACGCGCATC
TGGGGCTCGGCGTCTGCCACCTGCGGCAGGAGGACCCGAAATCCGCGCTCTTCAGTTTCGACCGCTGCCTGGAGCTCAAC
GCCAGCCACGTGGACGCTCAGTTCGGCAAGGCGGTGGCGCTCCAATCGCTCGGTCACGCGGAAGATGCCTCGCAGATCTA
TCAGAAGATTCTGGAGAAGAATCCGGATTCCGAAGATTCACTGTCGAACCTGATCCTGATCGGGATGGCGAAGGAAGACT
TCGACATGGTGCGCGAGTATAGCGAGCACCTGCTGGAGCTGCGGCCGGAATCGACGGTCGCGCTGGAAGGTCTGGCGTCG
TGGGCCTGCGCGGCGGGCGAGCATGCGCTGACGGCCAAGTTCTGCACGCTGCTGGTAAACTCCGTGCCCGGGCATTTCGA
AGGTTGGTTCAACCTGGCTCTGGCGCATCAGAAATCGGGACGCTTCGAGCAGGCCGCCGAGGCCTACTCGGAATGCGTGA
AGCTGCGGCCGCAATCCTGCGAATCGCACACCAACCTCGGCATCGTGCGCGAGCAGACGGGAGACACCGCGGGTGCGCGC
AGCTCCTACGAACGCGCCATTAAGGCGGGTCCGGACGCGCTGGCTCCGTTGTGGAACCTGGCTCTTCTCCTGGAGCACGC
GGGACAGTTCGAGGAGTCGGAACGTTATTACAAACAGGTGCTGGATCGCGCACCGAAAGAAGAAGAGGCGCGCTTCCGCA
TGGGCTTCCTCCGGCTGCAGCGTGAAGACTATCGCGGCGCCGCCGAGGCCTTCGAAGGCTGCCTGAAGTACCGTCCGGCC
TGGCCGGAAGCGCACGCCAACCTGGCGCTGGCCTACAGCGGCATGGGCGAGCGCGATCACGCCGAGCGGCTGTACGAAAA
GATGCTCGACGCCGATCCCAAGTCGATGGACGCGCTGCGCGGACTCGCGGCGCTTTCGATTCAGGCGAACGATTACGACA
CGGCGCTCGAATTCCACGTGCGCCTGATCGATCTCGGCGATCGCACCCCCGAAGTGCTCTACAACGCGGGCCTGATGTAC
GAGAAGGCCGGCCAGCAGGATAAGTCCGTCCGGCTCTACCGCGACGCCCTGGCGCAGCAGGCCGACATGCCGGAAGCGCT
GCTCAACCTGGGACGCATCCTGGAAAGCAACGGCAAGGCGGAAGAAGCCCGCACCTGCTGGGCGAAGGCTCTCGAAGCCG
AGCCGGCATTGGCGCAGGGCTACTTCGGACCGGCCATCGACTAG

Upstream 100 bases:

>100_bases
GCGGCGGTATCGGTTTCATGGGCGCTCATGACGATCGCGCCCGACTCTATTGGGTTAGGATCTCCTCTTCAGACAATATC
GGCAAGGAGCATCAGAAGAA

Downstream 100 bases:

>100_bases
TTACCCTTCGGGCCACGAATGGACGCAACCTTGCGCATTCGTGGCCCGAACTGTTTCTAAGCGGAATAGGAGACCCGTTC
AGGGCCGCGCCACCGTCCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSTAMRTPQKVQSLRTHDIDAGEKTAGSQSHLARAVTLHLAGRREEALKQLQRAIAANEASAEIYRAMGHIQFELGSFDE
AAKSYRILVQVKPQYSMGWFNLAVCLERAGVWEDAAQSFHRAATLEPGYLDAHLGLGVCHLRQEDPKSALFSFDRCLELN
ASHVDAQFGKAVALQSLGHAEDASQIYQKILEKNPDSEDSLSNLILIGMAKEDFDMVREYSEHLLELRPESTVALEGLAS
WACAAGEHALTAKFCTLLVNSVPGHFEGWFNLALAHQKSGRFEQAAEAYSECVKLRPQSCESHTNLGIVREQTGDTAGAR
SSYERAIKAGPDALAPLWNLALLLEHAGQFEESERYYKQVLDRAPKEEEARFRMGFLRLQREDYRGAAEAFEGCLKYRPA
WPEAHANLALAYSGMGERDHAERLYEKMLDADPKSMDALRGLAALSIQANDYDTALEFHVRLIDLGDRTPEVLYNAGLMY
EKAGQQDKSVRLYRDALAQQADMPEALLNLGRILESNGKAEEARTCWAKALEAEPALAQGYFGPAID

Sequences:

>Translated_547_residues
MSTAMRTPQKVQSLRTHDIDAGEKTAGSQSHLARAVTLHLAGRREEALKQLQRAIAANEASAEIYRAMGHIQFELGSFDE
AAKSYRILVQVKPQYSMGWFNLAVCLERAGVWEDAAQSFHRAATLEPGYLDAHLGLGVCHLRQEDPKSALFSFDRCLELN
ASHVDAQFGKAVALQSLGHAEDASQIYQKILEKNPDSEDSLSNLILIGMAKEDFDMVREYSEHLLELRPESTVALEGLAS
WACAAGEHALTAKFCTLLVNSVPGHFEGWFNLALAHQKSGRFEQAAEAYSECVKLRPQSCESHTNLGIVREQTGDTAGAR
SSYERAIKAGPDALAPLWNLALLLEHAGQFEESERYYKQVLDRAPKEEEARFRMGFLRLQREDYRGAAEAFEGCLKYRPA
WPEAHANLALAYSGMGERDHAERLYEKMLDADPKSMDALRGLAALSIQANDYDTALEFHVRLIDLGDRTPEVLYNAGLMY
EKAGQQDKSVRLYRDALAQQADMPEALLNLGRILESNGKAEEARTCWAKALEAEPALAQGYFGPAID
>Mature_546_residues
STAMRTPQKVQSLRTHDIDAGEKTAGSQSHLARAVTLHLAGRREEALKQLQRAIAANEASAEIYRAMGHIQFELGSFDEA
AKSYRILVQVKPQYSMGWFNLAVCLERAGVWEDAAQSFHRAATLEPGYLDAHLGLGVCHLRQEDPKSALFSFDRCLELNA
SHVDAQFGKAVALQSLGHAEDASQIYQKILEKNPDSEDSLSNLILIGMAKEDFDMVREYSEHLLELRPESTVALEGLASW
ACAAGEHALTAKFCTLLVNSVPGHFEGWFNLALAHQKSGRFEQAAEAYSECVKLRPQSCESHTNLGIVREQTGDTAGARS
SYERAIKAGPDALAPLWNLALLLEHAGQFEESERYYKQVLDRAPKEEEARFRMGFLRLQREDYRGAAEAFEGCLKYRPAW
PEAHANLALAYSGMGERDHAERLYEKMLDADPKSMDALRGLAALSIQANDYDTALEFHVRLIDLGDRTPEVLYNAGLMYE
KAGQQDKSVRLYRDALAQQADMPEALLNLGRILESNGKAEEARTCWAKALEAEPALAQGYFGPAID

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=461, Percent_Identity=25.5965292841649, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI32307148, Length=461, Percent_Identity=25.5965292841649, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI83415184, Length=381, Percent_Identity=25.9842519685039, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI301336134, Length=381, Percent_Identity=25.9842519685039, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI22749211, Length=285, Percent_Identity=24.5614035087719, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI118766330, Length=219, Percent_Identity=23.7442922374429, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI118766328, Length=219, Percent_Identity=23.7442922374429, Blast_Score=70, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=444, Percent_Identity=24.0990990990991, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115532692, Length=435, Percent_Identity=24.367816091954, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25147174, Length=232, Percent_Identity=22.8448275862069, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17647755, Length=461, Percent_Identity=25.8134490238612, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585827, Length=461, Percent_Identity=25.8134490238612, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585829, Length=461, Percent_Identity=25.8134490238612, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24647123, Length=226, Percent_Identity=23.8938053097345, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 60721; Mature: 60590

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAMRTPQKVQSLRTHDIDAGEKTAGSQSHLARAVTLHLAGRREEALKQLQRAIAANEA
CCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
SAEIYRAMGHIQFELGSFDEAAKSYRILVQVKPQYSMGWFNLAVCLERAGVWEDAAQSFH
HHHHHHHHCCEEEECCCHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHH
RAATLEPGYLDAHLGLGVCHLRQEDPKSALFSFDRCLELNASHVDAQFGKAVALQSLGHA
HHCCCCCCCEEHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
EDASQIYQKILEKNPDSEDSLSNLILIGMAKEDFDMVREYSEHLLELRPESTVALEGLAS
CHHHHHHHHHHHCCCCCCHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
WACAAGEHALTAKFCTLLVNSVPGHFEGWFNLALAHQKSGRFEQAAEAYSECVKLRPQSC
HHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC
ESHTNLGIVREQTGDTAGARSSYERAIKAGPDALAPLWNLALLLEHAGQFEESERYYKQV
CCCCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LDRAPKEEEARFRMGFLRLQREDYRGAAEAFEGCLKYRPAWPEAHANLALAYSGMGERDH
HHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHH
AERLYEKMLDADPKSMDALRGLAALSIQANDYDTALEFHVRLIDLGDRTPEVLYNAGLMY
HHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCHHHEEEEEEEEECCCCCHHHHHHCCCHH
EKAGQQDKSVRLYRDALAQQADMPEALLNLGRILESNGKAEEARTCWAKALEAEPALAQG
HHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHCC
YFGPAID
CCCCCCC
>Mature Secondary Structure 
STAMRTPQKVQSLRTHDIDAGEKTAGSQSHLARAVTLHLAGRREEALKQLQRAIAANEA
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
SAEIYRAMGHIQFELGSFDEAAKSYRILVQVKPQYSMGWFNLAVCLERAGVWEDAAQSFH
HHHHHHHHCCEEEECCCHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHH
RAATLEPGYLDAHLGLGVCHLRQEDPKSALFSFDRCLELNASHVDAQFGKAVALQSLGHA
HHCCCCCCCEEHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
EDASQIYQKILEKNPDSEDSLSNLILIGMAKEDFDMVREYSEHLLELRPESTVALEGLAS
CHHHHHHHHHHHCCCCCCHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
WACAAGEHALTAKFCTLLVNSVPGHFEGWFNLALAHQKSGRFEQAAEAYSECVKLRPQSC
HHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC
ESHTNLGIVREQTGDTAGARSSYERAIKAGPDALAPLWNLALLLEHAGQFEESERYYKQV
CCCCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LDRAPKEEEARFRMGFLRLQREDYRGAAEAFEGCLKYRPAWPEAHANLALAYSGMGERDH
HHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHH
AERLYEKMLDADPKSMDALRGLAALSIQANDYDTALEFHVRLIDLGDRTPEVLYNAGLMY
HHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCHHHEEEEEEEEECCCCCHHHHHHCCCHH
EKAGQQDKSVRLYRDALAQQADMPEALLNLGRILESNGKAEEARTCWAKALEAEPALAQG
HHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHCC
YFGPAID
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]