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The map label for this gene is nhaA2 [H]

Identifier: 116622720

GI number: 116622720

Start: 4577450

End: 4578331

Strand: Direct

Name: nhaA2 [H]

Synonym: Acid_3619

Alternate gene names: 116622720

Gene position: 4577450-4578331 (Clockwise)

Preceding gene: 116622719

Following gene: 116622723

Centisome position: 45.93

GC content: 56.92

Gene sequence:

>882_bases
ATGCGGGTTGCGAGCTGGAAGTGGGTAGTAGGGATCGTCTTGGGGAGCGCGGCAATCCTGCTGGCTCAGGAATGGCAAAG
CGTCGCCAACCTGGCGGGCGTTGATTTCGCGGGTTTAAGTGCCGCGAAGAAAAACACCGCTCTTCACGCCCTGCGCAATT
ACGATTGTACTTGCGGGTGCGGGATGAAGGTGGCGGAATGCCGCGTTAAAGACCCGAGTTGCTCCTACAGCCGCGCACTT
TCGGGCACTCTTGTTGACGCAATACGTAAGGGTAAAACGGAAGCGGCGGCGGTAGAGGAAGCTAAGGCTTCGAAGCACGG
ACATGTAGCCGAAGCTAAACTACTGGACGATCCCGTGGCGATACCGACTCTGGGTTCGCCGATGATCGGTCCGGCGAATG
CCCGTATCGTGTTAGTGGAGTTCTCCGATTTTCAGTGTCCTTACTGCGTCAAGGCAGTGGCCAAGATCAACGCCATTCTG
CAGGCTTATCCCAATGATGTGCGCCTGATCTTCAAGCAATTTCCCCTGGAAACCCACCCTCAGGCATCGATCTCCGCGGC
GGCGGCGCTGGCAGCGCACAATCAAGGTAAATTCTGGGCGATGCACGATACGCTTTTCGCCAACCGTACGCAGCTCTCGC
GCCAGAATATTCTGGGTTGGGCCGCGAAACTCGGACTCGATATGAAGCGTTTCACCGCCGATCTGGATTCAGATGCAATC
AAGAAGGCGGTCATCAAGGATACGCAGGATGGCGACAAAGCCGGAGTAGAGGGCACACCCACAGTTTTCATAGACGGGCA
GCGCTACAACGGAGAGCTTGCGCTCGATGCCGTGAAGCCGGTGATCGACGGCGAATTGAAGCGGCTCTCGGCGAAGAAAT
AG

Upstream 100 bases:

>100_bases
GATTTGGCTGGTCGCGTTCCTCATGGGCCGTCGAGCAATATAACCATTGGGCGGGTTCTAGCCCGCCCAACGACCTTCCT
TTCGCAATTACAATAAAGGA

Downstream 100 bases:

>100_bases
TTTCGTTGCCGTTGTCTCGCCAGGCAGCCTCTATTCGGCTGTCTTGAGAATCAGTTCCACCGCGCCGGAGAGTCGGGCCC
AATTTGCCGTTTCGGACTCG

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MRVASWKWVVGIVLGSAAILLAQEWQSVANLAGVDFAGLSAAKKNTALHALRNYDCTCGCGMKVAECRVKDPSCSYSRAL
SGTLVDAIRKGKTEAAAVEEAKASKHGHVAEAKLLDDPVAIPTLGSPMIGPANARIVLVEFSDFQCPYCVKAVAKINAIL
QAYPNDVRLIFKQFPLETHPQASISAAAALAAHNQGKFWAMHDTLFANRTQLSRQNILGWAAKLGLDMKRFTADLDSDAI
KKAVIKDTQDGDKAGVEGTPTVFIDGQRYNGELALDAVKPVIDGELKRLSAKK

Sequences:

>Translated_293_residues
MRVASWKWVVGIVLGSAAILLAQEWQSVANLAGVDFAGLSAAKKNTALHALRNYDCTCGCGMKVAECRVKDPSCSYSRAL
SGTLVDAIRKGKTEAAAVEEAKASKHGHVAEAKLLDDPVAIPTLGSPMIGPANARIVLVEFSDFQCPYCVKAVAKINAIL
QAYPNDVRLIFKQFPLETHPQASISAAAALAAHNQGKFWAMHDTLFANRTQLSRQNILGWAAKLGLDMKRFTADLDSDAI
KKAVIKDTQDGDKAGVEGTPTVFIDGQRYNGELALDAVKPVIDGELKRLSAKK
>Mature_293_residues
MRVASWKWVVGIVLGSAAILLAQEWQSVANLAGVDFAGLSAAKKNTALHALRNYDCTCGCGMKVAECRVKDPSCSYSRAL
SGTLVDAIRKGKTEAAAVEEAKASKHGHVAEAKLLDDPVAIPTLGSPMIGPANARIVLVEFSDFQCPYCVKAVAKINAIL
QAYPNDVRLIFKQFPLETHPQASISAAAALAAHNQGKFWAMHDTLFANRTQLSRQNILGWAAKLGLDMKRFTADLDSDAI
KKAVIKDTQDGDKAGVEGTPTVFIDGQRYNGELALDAVKPVIDGELKRLSAKK

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 31417; Mature: 31417

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVASWKWVVGIVLGSAAILLAQEWQSVANLAGVDFAGLSAAKKNTALHALRNYDCTCGC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
GMKVAECRVKDPSCSYSRALSGTLVDAIRKGKTEAAAVEEAKASKHGHVAEAKLLDDPVA
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCC
IPTLGSPMIGPANARIVLVEFSDFQCPYCVKAVAKINAILQAYPNDVRLIFKQFPLETHP
CCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
QASISAAAALAAHNQGKFWAMHDTLFANRTQLSRQNILGWAAKLGLDMKRFTADLDSDAI
CHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHH
KKAVIKDTQDGDKAGVEGTPTVFIDGQRYNGELALDAVKPVIDGELKRLSAKK
HHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRVASWKWVVGIVLGSAAILLAQEWQSVANLAGVDFAGLSAAKKNTALHALRNYDCTCGC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
GMKVAECRVKDPSCSYSRALSGTLVDAIRKGKTEAAAVEEAKASKHGHVAEAKLLDDPVA
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCC
IPTLGSPMIGPANARIVLVEFSDFQCPYCVKAVAKINAILQAYPNDVRLIFKQFPLETHP
CCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
QASISAAAALAAHNQGKFWAMHDTLFANRTQLSRQNILGWAAKLGLDMKRFTADLDSDAI
CHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHH
KKAVIKDTQDGDKAGVEGTPTVFIDGQRYNGELALDAVKPVIDGELKRLSAKK
HHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA