Click here to switch to the map view.

The map label for this gene is rsbU [H]

Identifier: 116622712

GI number: 116622712

Start: 4570799

End: 4571785

Strand: Reverse

Name: rsbU [H]

Synonym: Acid_3611

Alternate gene names: 116622712

Gene position: 4571785-4570799 (Counterclockwise)

Preceding gene: 116622714

Following gene: 116622710

Centisome position: 45.88

GC content: 64.64

Gene sequence:

>987_bases
ATGAACGCAGCATCCGCCGTTGCCGCCCATACCTTCCGTCCCCAGCTTCTCGAACGGCGCAGCCGGCTTCAGGCGGCCGC
CGGCTCCGTTCCCGACGACTACTTCGCCGGTCTCATCGCCGAAATCGATGCCGCGCTCGCACGAATCGAACACGGCCAGT
TCGGCATCTGCGAGTCCTGCCACGATTCAATCGAACAGGACCGGCTCGCGCACAATCCTCTGATCCGGTTTTGCCTGGAC
CATCTGAGTCAAGCCGAGCTGCGCGCCCATCAACAGGACCTCGACCTGGCCACGCAAATCCAGTCCAAGCTCCTGCCGCC
CAGGGACCTCGCGCTCGATCACTGGGAGACGCAGTACCGTTATCAACCTGTCGGTGCGGTAGGCGGCGATTATTGCGAGC
TGATCATTCTGGGCGATGGCAAGTCGCTCTTCTTCGCCGTCGGCGACGTTGCCGGGAAAGGAGTGGCCGCCTCGCTATTG
ATGACTCACCTCAGCGCGATCTTCCGCAGTCTGCTGTCGCTCGACTTGTCGCTCGCCGACCTGGTTGCCCGCGCCAATCG
GTTGTTCTGCGAGAGTACCGCCCCGGCCCATTACGCGACCCTGGTCTGTGGCCGCGCCACGCCGCTCGGAATCGAACTCT
GCAGCGCCGGGCACTGTCCTCCGTTGGTCGTACGCCGCGATGCAACCGAGCGTTTGGATTCCACCGGCCTGCCCCTGGGC
CTCTTCTGCGGCGGTCAGTACGCCGTGCGCAACATCAACCTCGATGACGGCGAAAGTCTCGTCTTGTACTCCGACGGCAT
CACCGAGGCGCAGGATCCGGCAGGCGACGACTACCAGGAAGAGCGCCTGATCCGCGCGCTACGCGACCGCGTGGACCAAT
CCTCCGGCACGATGGCGGATGGCGTCCTACAGGACGTCGCCCGCTTCCGTCAAACCCGTCCGCCGGTCGACGATATGACC
CTGCTCATCGTGCGCCGCCGCCGCTGA

Upstream 100 bases:

>100_bases
ACATGCGGTATTCTCCAGGACAATTGAACGGCTCGAGATCTCCTGAAGAATGTTTTCAGACATTCCAGTGGGACAATATG
TCTTTTGGAGGGCTTTCACA

Downstream 100 bases:

>100_bases
CGCACTATCCCTTGCCTTGCCTTTATCCGTCAGGGAGCGCAGCGAACTCCACCACCCTAGCAGCGCCGCGTCTGAGCCGC
GACCGTCAGGGAGCGATCTC

Product: serine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MNAASAVAAHTFRPQLLERRSRLQAAAGSVPDDYFAGLIAEIDAALARIEHGQFGICESCHDSIEQDRLAHNPLIRFCLD
HLSQAELRAHQQDLDLATQIQSKLLPPRDLALDHWETQYRYQPVGAVGGDYCELIILGDGKSLFFAVGDVAGKGVAASLL
MTHLSAIFRSLLSLDLSLADLVARANRLFCESTAPAHYATLVCGRATPLGIELCSAGHCPPLVVRRDATERLDSTGLPLG
LFCGGQYAVRNINLDDGESLVLYSDGITEAQDPAGDDYQEERLIRALRDRVDQSSGTMADGVLQDVARFRQTRPPVDDMT
LLIVRRRR

Sequences:

>Translated_328_residues
MNAASAVAAHTFRPQLLERRSRLQAAAGSVPDDYFAGLIAEIDAALARIEHGQFGICESCHDSIEQDRLAHNPLIRFCLD
HLSQAELRAHQQDLDLATQIQSKLLPPRDLALDHWETQYRYQPVGAVGGDYCELIILGDGKSLFFAVGDVAGKGVAASLL
MTHLSAIFRSLLSLDLSLADLVARANRLFCESTAPAHYATLVCGRATPLGIELCSAGHCPPLVVRRDATERLDSTGLPLG
LFCGGQYAVRNINLDDGESLVLYSDGITEAQDPAGDDYQEERLIRALRDRVDQSSGTMADGVLQDVARFRQTRPPVDDMT
LLIVRRRR
>Mature_328_residues
MNAASAVAAHTFRPQLLERRSRLQAAAGSVPDDYFAGLIAEIDAALARIEHGQFGICESCHDSIEQDRLAHNPLIRFCLD
HLSQAELRAHQQDLDLATQIQSKLLPPRDLALDHWETQYRYQPVGAVGGDYCELIILGDGKSLFFAVGDVAGKGVAASLL
MTHLSAIFRSLLSLDLSLADLVARANRLFCESTAPAHYATLVCGRATPLGIELCSAGHCPPLVVRRDATERLDSTGLPLG
LFCGGQYAVRNINLDDGESLVLYSDGITEAQDPAGDDYQEERLIRALRDRVDQSSGTMADGVLQDVARFRQTRPPVDDMT
LLIVRRRR

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35874; Mature: 35874

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS51128 ZF_DKSA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAASAVAAHTFRPQLLERRSRLQAAAGSVPDDYFAGLIAEIDAALARIEHGQFGICESC
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
HDSIEQDRLAHNPLIRFCLDHLSQAELRAHQQDLDLATQIQSKLLPPRDLALDHWETQYR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHE
YQPVGAVGGDYCELIILGDGKSLFFAVGDVAGKGVAASLLMTHLSAIFRSLLSLDLSLAD
ECCCCCCCCCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVARANRLFCESTAPAHYATLVCGRATPLGIELCSAGHCPPLVVRRDATERLDSTGLPLG
HHHHHHHHHCCCCCCHHHHHHEECCCCCCCHHHHCCCCCCCEEEECCHHHHHHCCCCCEE
LFCGGQYAVRNINLDDGESLVLYSDGITEAQDPAGDDYQEERLIRALRDRVDQSSGTMAD
EEECCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHH
GVLQDVARFRQTRPPVDDMTLLIVRRRR
HHHHHHHHHHHCCCCCCHHEEEEEECCC
>Mature Secondary Structure
MNAASAVAAHTFRPQLLERRSRLQAAAGSVPDDYFAGLIAEIDAALARIEHGQFGICESC
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
HDSIEQDRLAHNPLIRFCLDHLSQAELRAHQQDLDLATQIQSKLLPPRDLALDHWETQYR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHE
YQPVGAVGGDYCELIILGDGKSLFFAVGDVAGKGVAASLLMTHLSAIFRSLLSLDLSLAD
ECCCCCCCCCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVARANRLFCESTAPAHYATLVCGRATPLGIELCSAGHCPPLVVRRDATERLDSTGLPLG
HHHHHHHHHCCCCCCHHHHHHEECCCCCCCHHHHCCCCCCCEEEECCHHHHHHCCCCCEE
LFCGGQYAVRNINLDDGESLVLYSDGITEAQDPAGDDYQEERLIRALRDRVDQSSGTMAD
EEECCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHH
GVLQDVARFRQTRPPVDDMTLLIVRRRR
HHHHHHHHHHHCCCCCCHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]