Click here to switch to the map view.

The map label for this gene is 116622596

Identifier: 116622596

GI number: 116622596

Start: 4422256

End: 4423383

Strand: Direct

Name: 116622596

Synonym: Acid_3494

Alternate gene names: NA

Gene position: 4422256-4423383 (Clockwise)

Preceding gene: 116622595

Following gene: 116622597

Centisome position: 44.38

GC content: 62.59

Gene sequence:

>1128_bases
ATGACGCTTCGCAGCAGTGCGCTCGGTCTCGCGGTCGCGGCATGGCTCGCTTTTGGCGCAATCGCGGAGCAGTCTTCGCC
CGACGCGCTGCTCCGCCACGCCATCGAGCTGCACCAGGCCGGCGACATCCCAGGTGCTATCGAGGAGTATCGAGCGTTCC
TGAAGCAGTCTCCCAACAATGTGATGGCGCGGTCCAATCTCGGCGCGGCCCTTTCCAAGTCCGGCCGGTACGAAGAGGCC
ACCGTCGAGTACCGCAAGGCGTTGGATCTGGAACCGCGCAATCTTCCCGTTCGGGTCAACCTGGCGCTCGCCTACTACAA
GACCGCCCAGATCGCGGATGCCGCGGAGGAGCTGACCAAAGCTGTTAAGCAGGGGCCTCCCAACAGGCAGGCCATCTTCC
TGCTCGCCGATTGCGATCTGCGCCTCGGCGAAAACAAGAAAGTGATCGAGCTGCTGTCTCCGCTGGAAAAGGAATCGCCG
AACGACAAGGCGCTGGTCTACCTCCTGGGCACGGCGCTCATCCGCGACAATCAGCCGGCTCGCGGTCAATTGCTGGTGGA
CCGCATCCTGCGCGAAGGCGAATCCGCCGAGGCGCACCTGCTGCTCGGCACCACCAAAATGAACGCGCAGGAATTCGCCG
GCGCTCTGGTCGATCTCAAGAAGGCTGCGGATCTCAATCCGCAGCTTCCCGACGTCTTCTCTTACTATGGCCTTGCGCTG
CTCAGCACCGGCGATGTGGCCGCGGCCACCACTGCCTTCCGCAAGGAGCTCGAGTCCAATCCCAACGACTTCGTTTCCAA
CCTGCAGCTCGGCTCCATCTTCAAACAGGAGCAGCGCTACGACCAAGCCTTGAGTTCCTTCGAACGCGCCCTGCGAGTGC
GACCCGGCGACCCCGGCGTGCGCTACCAGCTGGCCACCCTTGATGTAATCTCGGGCAATCTCGACCAGGCCTGCTCCAGG
CTGGAACAGTTGATCAAGGAAACGCCGCACTTCGTGGAGGCCCACGTCACGCTGGCGACGGTCTACTATCGCCTCAAACG
CAAAGCGGATGGCGATCGCGAACGCGCCACCGTCCTGAAACTGAACGCCGAAAGCCAGGCAGCCCAACCCGGGGCAAAAA
TGCAATGA

Upstream 100 bases:

>100_bases
ACGGCAAAGTCGCGTTTAGCACCCGGCTCGGCGAGCTTGAATTCCGCCCCGCTGACCTGGAAACCGCGATTCGTGAGATC
CTGTCAAAAACGGGGGTCGA

Downstream 100 bases:

>100_bases
GAGTGGCATGCTGGAGCGCGGCTTGTCTGCTGCCGCTCCTCGCCATCGCAGGTCCGCCCGTTGCCGGCGATCAGGTTTGT
GCCGAGTGCCATGGGAAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTLRSSALGLAVAAWLAFGAIAEQSSPDALLRHAIELHQAGDIPGAIEEYRAFLKQSPNNVMARSNLGAALSKSGRYEEA
TVEYRKALDLEPRNLPVRVNLALAYYKTAQIADAAEELTKAVKQGPPNRQAIFLLADCDLRLGENKKVIELLSPLEKESP
NDKALVYLLGTALIRDNQPARGQLLVDRILREGESAEAHLLLGTTKMNAQEFAGALVDLKKAADLNPQLPDVFSYYGLAL
LSTGDVAAATTAFRKELESNPNDFVSNLQLGSIFKQEQRYDQALSSFERALRVRPGDPGVRYQLATLDVISGNLDQACSR
LEQLIKETPHFVEAHVTLATVYYRLKRKADGDRERATVLKLNAESQAAQPGAKMQ

Sequences:

>Translated_375_residues
MTLRSSALGLAVAAWLAFGAIAEQSSPDALLRHAIELHQAGDIPGAIEEYRAFLKQSPNNVMARSNLGAALSKSGRYEEA
TVEYRKALDLEPRNLPVRVNLALAYYKTAQIADAAEELTKAVKQGPPNRQAIFLLADCDLRLGENKKVIELLSPLEKESP
NDKALVYLLGTALIRDNQPARGQLLVDRILREGESAEAHLLLGTTKMNAQEFAGALVDLKKAADLNPQLPDVFSYYGLAL
LSTGDVAAATTAFRKELESNPNDFVSNLQLGSIFKQEQRYDQALSSFERALRVRPGDPGVRYQLATLDVISGNLDQACSR
LEQLIKETPHFVEAHVTLATVYYRLKRKADGDRERATVLKLNAESQAAQPGAKMQ
>Mature_374_residues
TLRSSALGLAVAAWLAFGAIAEQSSPDALLRHAIELHQAGDIPGAIEEYRAFLKQSPNNVMARSNLGAALSKSGRYEEAT
VEYRKALDLEPRNLPVRVNLALAYYKTAQIADAAEELTKAVKQGPPNRQAIFLLADCDLRLGENKKVIELLSPLEKESPN
DKALVYLLGTALIRDNQPARGQLLVDRILREGESAEAHLLLGTTKMNAQEFAGALVDLKKAADLNPQLPDVFSYYGLALL
STGDVAAATTAFRKELESNPNDFVSNLQLGSIFKQEQRYDQALSSFERALRVRPGDPGVRYQLATLDVISGNLDQACSRL
EQLIKETPHFVEAHVTLATVYYRLKRKADGDRERATVLKLNAESQAAQPGAKMQ

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=320, Percent_Identity=24.6875, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI32307148, Length=320, Percent_Identity=24.6875, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115532690, Length=329, Percent_Identity=26.4437689969605, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115532692, Length=319, Percent_Identity=26.3322884012539, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17647755, Length=295, Percent_Identity=25.4237288135593, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24585827, Length=295, Percent_Identity=25.4237288135593, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24585829, Length=295, Percent_Identity=25.4237288135593, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 41108; Mature: 40977

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRSSALGLAVAAWLAFGAIAEQSSPDALLRHAIELHQAGDIPGAIEEYRAFLKQSPNN
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
VMARSNLGAALSKSGRYEEATVEYRKALDLEPRNLPVRVNLALAYYKTAQIADAAEELTK
HHHHCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHH
AVKQGPPNRQAIFLLADCDLRLGENKKVIELLSPLEKESPNDKALVYLLGTALIRDNQPA
HHHCCCCCCCEEEEEEECCEEECCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCC
RGQLLVDRILREGESAEAHLLLGTTKMNAQEFAGALVDLKKAADLNPQLPDVFSYYGLAL
CHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LSTGDVAAATTAFRKELESNPNDFVSNLQLGSIFKQEQRYDQALSSFERALRVRPGDPGV
CCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RYQLATLDVISGNLDQACSRLEQLIKETPHFVEAHVTLATVYYRLKRKADGDRERATVLK
EEEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LNAESQAAQPGAKMQ
ECCCHHHCCCCCCCC
>Mature Secondary Structure 
TLRSSALGLAVAAWLAFGAIAEQSSPDALLRHAIELHQAGDIPGAIEEYRAFLKQSPNN
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
VMARSNLGAALSKSGRYEEATVEYRKALDLEPRNLPVRVNLALAYYKTAQIADAAEELTK
HHHHCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHH
AVKQGPPNRQAIFLLADCDLRLGENKKVIELLSPLEKESPNDKALVYLLGTALIRDNQPA
HHHCCCCCCCEEEEEEECCEEECCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCC
RGQLLVDRILREGESAEAHLLLGTTKMNAQEFAGALVDLKKAADLNPQLPDVFSYYGLAL
CHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LSTGDVAAATTAFRKELESNPNDFVSNLQLGSIFKQEQRYDQALSSFERALRVRPGDPGV
CCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RYQLATLDVISGNLDQACSRLEQLIKETPHFVEAHVTLATVYYRLKRKADGDRERATVLK
EEEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LNAESQAAQPGAKMQ
ECCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]