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The map label for this gene is nreB [H]

Identifier: 116622584

GI number: 116622584

Start: 4400782

End: 4402104

Strand: Reverse

Name: nreB [H]

Synonym: Acid_3482

Alternate gene names: 116622584

Gene position: 4402104-4400782 (Counterclockwise)

Preceding gene: 116622588

Following gene: 116622583

Centisome position: 44.17

GC content: 63.57

Gene sequence:

>1323_bases
GTGCAATCCAGATCGCCGACACCCCGCTTACTCGCGGGGCTTGCCATTACGCTCTCCGCGGTGGCCCTCTACTCGGGCTA
CACGGTGACGCAACTGCGCGGCCTGGAGCGCCTGCAGGGCGGCATCATCGATCGCAATCGCGCCGATTCGCTCCAGCTTC
TCCGCATACAGAACAACCTGAACTCGCTAGGCCTGACCATGCGCGACATGTTGGATGGCAGCGAGCCTTATCCCCTGACC
GCCTGGCAGGGACAATTCCGCAGGATGCGCACCGATCTCGAAGACGCCATTGCGCGCGAAGCACAGTCCTCGCCCCTGGA
TCGCGACCCGGAGCAGCGCCGGTACCTGAGCGACTCTCTACGCCAGTTCTGGGACGCGCTCGACCGCATCTTCGCCCTGG
CGCAAACCGGGCAGGAGGCCGAAGCCCGCACGTTGATCCGCCTCTCCCTGCAAGCTCGCCAGGAAGCGATCGTCACCACC
GTCGCGCGCCTGCTCGTGCTCAACAACGAAGCCGAGCAGCAGGCGGCACTCCGCATACGCGGAGTGTATGCCGGAGTAGA
GCGCAATGTCTACCTGTTTGTCGCGGCGATGCTGGTATTGATTTTGCTCACCAGCCTCTACCTGGTGCATTCCAATCGCG
CCCTGTTCCAGGAAGTGGCAGCGCTCTCCGCGCGGCGCAGTGAGCTCGCACAGCAGTTAATCGCCATGCAGGAGAGCACC
TTCAGCTCCATCTCCCGCGACCTGCACGACGATTTCGGACAGATCCTCACCGCGATCGGCAGCATGTTGCAGCGCACCGG
GCGGCGGGCCGCCGACCCCGAGTCGGTACGCGCCGATCTGCGCGAAGTGCAGGAGATCGTGCAATCCACGCTCGACAAGG
TGCGGACGCTCTCGCACGCATTGCATCCGGTGATCCTCGACGAGATGGGCTTCGAAGGCGCGCTCGATCAGTATCTGCCT
GGTTTTCAGAAACAGACGGGGATTGAGGTACGCTATGAGAAGTCCGGAGCGGCCCGCGAGCTCGATCGCGGGGTCACGAT
CCACCTCTATCGCGTCATGCAGGAGGCGTTAAACAATATCGCGAGGCATTCGCAATCCAAGCGCGCGGACGTGCGCCTGC
GTTATCTGACCGACACCGTCGTACTCGAAGTGGAAGATCACGGGGTGGGCTTCGGAAATTCACCCGTTCACGGGCTGGGG
CTGGTCTCCATGCGCGAGCGCGCCGACCTGGTGAACGGCCGCTTGGATCTGGAGAACTGCAGTTCCGGCGGCGCGCTGGT
TCGCCTCACGGTTCCCGCCGGCACGCAAGAGGTTCATGCCTGA

Upstream 100 bases:

>100_bases
GCAGACGCTTGTAGGACATGCCCTCTGAGTATGCCGTAATTTCTCGTCAGCTTATTACACCCGCACTGGGACCGCAATAG
TAGGAAAATACTAGCTGACT

Downstream 100 bases:

>100_bases
AGCACCGATTTCCGTGCTCCTGGTGGACGACCACAGCCTGGTGCGCCGCGGCTTCCGCCGCATGCTGGAGGACGACCCCG
CAATCGTCGTGGTGGGTGAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MQSRSPTPRLLAGLAITLSAVALYSGYTVTQLRGLERLQGGIIDRNRADSLQLLRIQNNLNSLGLTMRDMLDGSEPYPLT
AWQGQFRRMRTDLEDAIAREAQSSPLDRDPEQRRYLSDSLRQFWDALDRIFALAQTGQEAEARTLIRLSLQARQEAIVTT
VARLLVLNNEAEQQAALRIRGVYAGVERNVYLFVAAMLVLILLTSLYLVHSNRALFQEVAALSARRSELAQQLIAMQEST
FSSISRDLHDDFGQILTAIGSMLQRTGRRAADPESVRADLREVQEIVQSTLDKVRTLSHALHPVILDEMGFEGALDQYLP
GFQKQTGIEVRYEKSGAARELDRGVTIHLYRVMQEALNNIARHSQSKRADVRLRYLTDTVVLEVEDHGVGFGNSPVHGLG
LVSMRERADLVNGRLDLENCSSGGALVRLTVPAGTQEVHA

Sequences:

>Translated_440_residues
MQSRSPTPRLLAGLAITLSAVALYSGYTVTQLRGLERLQGGIIDRNRADSLQLLRIQNNLNSLGLTMRDMLDGSEPYPLT
AWQGQFRRMRTDLEDAIAREAQSSPLDRDPEQRRYLSDSLRQFWDALDRIFALAQTGQEAEARTLIRLSLQARQEAIVTT
VARLLVLNNEAEQQAALRIRGVYAGVERNVYLFVAAMLVLILLTSLYLVHSNRALFQEVAALSARRSELAQQLIAMQEST
FSSISRDLHDDFGQILTAIGSMLQRTGRRAADPESVRADLREVQEIVQSTLDKVRTLSHALHPVILDEMGFEGALDQYLP
GFQKQTGIEVRYEKSGAARELDRGVTIHLYRVMQEALNNIARHSQSKRADVRLRYLTDTVVLEVEDHGVGFGNSPVHGLG
LVSMRERADLVNGRLDLENCSSGGALVRLTVPAGTQEVHA
>Mature_440_residues
MQSRSPTPRLLAGLAITLSAVALYSGYTVTQLRGLERLQGGIIDRNRADSLQLLRIQNNLNSLGLTMRDMLDGSEPYPLT
AWQGQFRRMRTDLEDAIAREAQSSPLDRDPEQRRYLSDSLRQFWDALDRIFALAQTGQEAEARTLIRLSLQARQEAIVTT
VARLLVLNNEAEQQAALRIRGVYAGVERNVYLFVAAMLVLILLTSLYLVHSNRALFQEVAALSARRSELAQQLIAMQEST
FSSISRDLHDDFGQILTAIGSMLQRTGRRAADPESVRADLREVQEIVQSTLDKVRTLSHALHPVILDEMGFEGALDQYLP
GFQKQTGIEVRYEKSGAARELDRGVTIHLYRVMQEALNNIARHSQSKRADVRLRYLTDTVVLEVEDHGVGFGNSPVHGLG
LVSMRERADLVNGRLDLENCSSGGALVRLTVPAGTQEVHA

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=217, Percent_Identity=31.7972350230415, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787474, Length=217, Percent_Identity=29.9539170506912, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788812, Length=205, Percent_Identity=27.8048780487805, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49052; Mature: 49052

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSRSPTPRLLAGLAITLSAVALYSGYTVTQLRGLERLQGGIIDRNRADSLQLLRIQNNL
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCH
NSLGLTMRDMLDGSEPYPLTAWQGQFRRMRTDLEDAIAREAQSSPLDRDPEQRRYLSDSL
HHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RQFWDALDRIFALAQTGQEAEARTLIRLSLQARQEAIVTTVARLLVLNNEAEQQAALRIR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GVYAGVERNVYLFVAAMLVLILLTSLYLVHSNRALFQEVAALSARRSELAQQLIAMQEST
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSSISRDLHDDFGQILTAIGSMLQRTGRRAADPESVRADLREVQEIVQSTLDKVRTLSHA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHPVILDEMGFEGALDQYLPGFQKQTGIEVRYEKSGAARELDRGVTIHLYRVMQEALNNI
HHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHH
ARHSQSKRADVRLRYLTDTVVLEVEDHGVGFGNSPVHGLGLVSMRERADLVNGRLDLENC
HHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SSGGALVRLTVPAGTQEVHA
CCCCEEEEEECCCCCHHCCC
>Mature Secondary Structure
MQSRSPTPRLLAGLAITLSAVALYSGYTVTQLRGLERLQGGIIDRNRADSLQLLRIQNNL
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCH
NSLGLTMRDMLDGSEPYPLTAWQGQFRRMRTDLEDAIAREAQSSPLDRDPEQRRYLSDSL
HHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RQFWDALDRIFALAQTGQEAEARTLIRLSLQARQEAIVTTVARLLVLNNEAEQQAALRIR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GVYAGVERNVYLFVAAMLVLILLTSLYLVHSNRALFQEVAALSARRSELAQQLIAMQEST
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSSISRDLHDDFGQILTAIGSMLQRTGRRAADPESVRADLREVQEIVQSTLDKVRTLSHA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHPVILDEMGFEGALDQYLPGFQKQTGIEVRYEKSGAARELDRGVTIHLYRVMQEALNNI
HHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHH
ARHSQSKRADVRLRYLTDTVVLEVEDHGVGFGNSPVHGLGLVSMRERADLVNGRLDLENC
HHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
SSGGALVRLTVPAGTQEVHA
CCCCEEEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]