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The map label for this gene is macB [H]

Identifier: 116622572

GI number: 116622572

Start: 4388349

End: 4390766

Strand: Direct

Name: macB [H]

Synonym: Acid_3470

Alternate gene names: 116622572

Gene position: 4388349-4390766 (Clockwise)

Preceding gene: 116622571

Following gene: 116622573

Centisome position: 44.03

GC content: 64.76

Gene sequence:

>2418_bases
ATGAGCCTGGTGCAGGACGTTCGATTCGCGTGCCGGATCATCCGGAAGAATCCCTGGTTTTCCGCGGCGATTGTGGCCAC
GCTTGCCTTCGGGATGGGCGTCAACACCACGGTTTTCAGCCTGGTGAATGCGGTTCTGTATAAACCTCTGCCGTTCCGCG
GAGGCGAGCGCCTGGTGATGGCCTATGCCGTCAACCGGTCCAACGGCGAGAATACGATGCCGGTGTCGTACGCGGATTAC
CGCAATTTCCGCGACGAATCCCATTCCTTCGAGCGGCTGGAACTCTTCGACTCGCTGGCAGTGAATCTTGGGGAGCGGGG
AAATCCGCCGGAGCGCTTTCGCGGAGGGCGCATCAGCGCAGGCATGTTCGATATGCTGGCGACGCACCCGGTGCTCGGCC
GCGGCATGTCGCCCGCCGATGAGAAGGCGGGCGCCCCGCAGGTGGTGCTGCTCGGCTACGGTGTATGGCGCGATCGCTAC
GGCAAGGACCCGGGCGTGTTGGGCCGCGCGGTGCGGGTCAACGAAAAGCCGGCGGTGATCATCGGCGTGATGCCGGAGGG
ATTTAAGTTCCCCAATAACGAAGACCTTTGGCTCGCGGCTATTCCGGACGCCGCCGCTGAGAAGCGGAGCAATCGCGACT
ACCGGATGATCGGCATGCTGAAGCCGGGAATTCCGATTACCGAAGCGCGCGCCGACCTGGGTGCGATCGCCAAACGCCTG
GCGCAGGCGTATCCCGAAACCAATAAGGATCACGGCGCGACGGTGCTGACCTTTCACGACGCGATGAACGGCGGCCCGAT
CCGGCTGGTCTTTCTGTTGATGATGGGGGCGGTGGGCTTCGTACTGCTGATTGCGTGCGCCAATGTGGCCAACATGCTGC
TCAGCCGCGCGGTGGAGCGTACGCGCGAAGTCTCGATCCGTACCGCGATGGGCGCCGGACGCTGGCGGCTGGTGGGGCAG
ATGCTGATCGAAAGCGTCCTGCTCGCGAGCCTGGGAGGGCTTCTCGGACTGGTGCTGGCGCGCGCCGGCATCAGCGCTTT
CGGACGCGCGGTGGCGGACGTGGGCAAGCCGTACTGGATTGATTTTTCGATGGACTACGTGGTGTTCGCCTACTTCGGCG
CGCTCACCATTCTGACCGGCCTTTTGTTCGGTCTGGCGCCCGCGCTGGCGGCAACGCGAGTCAATCTCAACGACGCCTTG
AAGGATGGCTCGCGGGGTTCGAGCGGCGGCAGCGGATATCTCTCGGGCGCCCTGGTGATTCTGCAGTTCACGCTTTCGGT
GGTGCTGTTGAGCGGGGCCGGCCTGATGATGCGGAGTTTTCTGTTGGCGCAGAGCGAGTTCGGCGGAATGAACGCCGACA
AGGTGCTGGTGGCGCGGGTCAGGCTGCCACAGGACCGCTATCCGAAGGACGCCGACCGGCAGCGCTTCTTCGACAAGCTG
ATGCCGCGGGTGGCGGCGTTGCCCGGTGTAAGTGCGTCGGCGATGGTTTCGGATTTGCCGGGCGACGGCTCGGCAACCAG
GCGCTTCGAAATCGCGGGCAGGCCGATCACGGAGGCGCGGCGGCTGCCCGCGGCGTCGGTGGTGATGGCCAATACCGGCT
ATCTGCAGTTACTCGGGTTGACGTTGCTGCGCGGCCGGGATTTCGAGGCGACGGACGGATTGCCCGGGAAGGAGACCGTG
ATTGTCAGCCAGACGATGGCGGCGCGCTTCTTCCCCAATCAGGATCCCGTCGGCCGGCAGCTGCGGGTCTACAAAGATGA
CGACAAGCCGCAGGCCTGGATGACGATTATCGGGGTGGCGCCGGATTTCCGGCAGAAGAACCCCTCGGATCCGGCGGACG
ATCCGGTGCTGCTGGTGCCTTACCGGTTCGACAGTTACTCGTCGATGGCATTGATGTTGCGGACGAATGGCAATCCTGCG
GCGCTGGCGCCCGCTTTGCGAAACGAAGTGCAGCAGATCGATACCGACCTGCCGCTGTTCGACATGATGACGCTGGCGGA
GCGATTCGGCAAGCAGCGGTGGTACTTGAGCGTCTTCGGGACGGTCTTCCTGATCTTCGCGATCATCGCGACGGCGATGG
CCGCGGTCGGAATTTACGCGGTGATGGCGCAGGCCGCCAACGGCCGCACGCGCGAGATCGGGGTGCGCATGGCGCTGGGC
GCGGACGAAGGTTCGATCCTCGCGCTGGTGCTGTCGCGAGGCGTGAAGCAACTTGGAACCGGAATGGTGCTGGGGTTGGC
CGCGGCGCTCGCGGTCTGCCGGCTGATGGCCAAGCTGCTGTTCATGGTGTCGCCGAATGACCTGGTGACCTTTGTCGCCG
TGACGCTCGTGCTGGGCACGGCGGGCATGGCGGCGATCTTCTTCCCCGCGCGCCGCGCGGCGCGGCTCGATCCCCTGAAG
GCGCTGCGGTACGAGTGA

Upstream 100 bases:

>100_bases
CAGGGCGAATCCACCATCTCCTTCGATAATCTGGACGAGAAGGCGAAAACTCCACCCGACAAGAAGTGAACTTTCCGCGG
GCGAGGTTCGTAACCCAGGC

Downstream 100 bases:

>100_bases
GGCGAGACCAGCATGAATGCGATCGTCGCATTCATGCTGGGGCTACCTTTCGATGTTCTTCCCCGGAATTTCGGTCCTGA
TCGTCAGTTCAACGATGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 805; Mature: 804

Protein sequence:

>805_residues
MSLVQDVRFACRIIRKNPWFSAAIVATLAFGMGVNTTVFSLVNAVLYKPLPFRGGERLVMAYAVNRSNGENTMPVSYADY
RNFRDESHSFERLELFDSLAVNLGERGNPPERFRGGRISAGMFDMLATHPVLGRGMSPADEKAGAPQVVLLGYGVWRDRY
GKDPGVLGRAVRVNEKPAVIIGVMPEGFKFPNNEDLWLAAIPDAAAEKRSNRDYRMIGMLKPGIPITEARADLGAIAKRL
AQAYPETNKDHGATVLTFHDAMNGGPIRLVFLLMMGAVGFVLLIACANVANMLLSRAVERTREVSIRTAMGAGRWRLVGQ
MLIESVLLASLGGLLGLVLARAGISAFGRAVADVGKPYWIDFSMDYVVFAYFGALTILTGLLFGLAPALAATRVNLNDAL
KDGSRGSSGGSGYLSGALVILQFTLSVVLLSGAGLMMRSFLLAQSEFGGMNADKVLVARVRLPQDRYPKDADRQRFFDKL
MPRVAALPGVSASAMVSDLPGDGSATRRFEIAGRPITEARRLPAASVVMANTGYLQLLGLTLLRGRDFEATDGLPGKETV
IVSQTMAARFFPNQDPVGRQLRVYKDDDKPQAWMTIIGVAPDFRQKNPSDPADDPVLLVPYRFDSYSSMALMLRTNGNPA
ALAPALRNEVQQIDTDLPLFDMMTLAERFGKQRWYLSVFGTVFLIFAIIATAMAAVGIYAVMAQAANGRTREIGVRMALG
ADEGSILALVLSRGVKQLGTGMVLGLAAALAVCRLMAKLLFMVSPNDLVTFVAVTLVLGTAGMAAIFFPARRAARLDPLK
ALRYE

Sequences:

>Translated_805_residues
MSLVQDVRFACRIIRKNPWFSAAIVATLAFGMGVNTTVFSLVNAVLYKPLPFRGGERLVMAYAVNRSNGENTMPVSYADY
RNFRDESHSFERLELFDSLAVNLGERGNPPERFRGGRISAGMFDMLATHPVLGRGMSPADEKAGAPQVVLLGYGVWRDRY
GKDPGVLGRAVRVNEKPAVIIGVMPEGFKFPNNEDLWLAAIPDAAAEKRSNRDYRMIGMLKPGIPITEARADLGAIAKRL
AQAYPETNKDHGATVLTFHDAMNGGPIRLVFLLMMGAVGFVLLIACANVANMLLSRAVERTREVSIRTAMGAGRWRLVGQ
MLIESVLLASLGGLLGLVLARAGISAFGRAVADVGKPYWIDFSMDYVVFAYFGALTILTGLLFGLAPALAATRVNLNDAL
KDGSRGSSGGSGYLSGALVILQFTLSVVLLSGAGLMMRSFLLAQSEFGGMNADKVLVARVRLPQDRYPKDADRQRFFDKL
MPRVAALPGVSASAMVSDLPGDGSATRRFEIAGRPITEARRLPAASVVMANTGYLQLLGLTLLRGRDFEATDGLPGKETV
IVSQTMAARFFPNQDPVGRQLRVYKDDDKPQAWMTIIGVAPDFRQKNPSDPADDPVLLVPYRFDSYSSMALMLRTNGNPA
ALAPALRNEVQQIDTDLPLFDMMTLAERFGKQRWYLSVFGTVFLIFAIIATAMAAVGIYAVMAQAANGRTREIGVRMALG
ADEGSILALVLSRGVKQLGTGMVLGLAAALAVCRLMAKLLFMVSPNDLVTFVAVTLVLGTAGMAAIFFPARRAARLDPLK
ALRYE
>Mature_804_residues
SLVQDVRFACRIIRKNPWFSAAIVATLAFGMGVNTTVFSLVNAVLYKPLPFRGGERLVMAYAVNRSNGENTMPVSYADYR
NFRDESHSFERLELFDSLAVNLGERGNPPERFRGGRISAGMFDMLATHPVLGRGMSPADEKAGAPQVVLLGYGVWRDRYG
KDPGVLGRAVRVNEKPAVIIGVMPEGFKFPNNEDLWLAAIPDAAAEKRSNRDYRMIGMLKPGIPITEARADLGAIAKRLA
QAYPETNKDHGATVLTFHDAMNGGPIRLVFLLMMGAVGFVLLIACANVANMLLSRAVERTREVSIRTAMGAGRWRLVGQM
LIESVLLASLGGLLGLVLARAGISAFGRAVADVGKPYWIDFSMDYVVFAYFGALTILTGLLFGLAPALAATRVNLNDALK
DGSRGSSGGSGYLSGALVILQFTLSVVLLSGAGLMMRSFLLAQSEFGGMNADKVLVARVRLPQDRYPKDADRQRFFDKLM
PRVAALPGVSASAMVSDLPGDGSATRRFEIAGRPITEARRLPAASVVMANTGYLQLLGLTLLRGRDFEATDGLPGKETVI
VSQTMAARFFPNQDPVGRQLRVYKDDDKPQAWMTIIGVAPDFRQKNPSDPADDPVLLVPYRFDSYSSMALMLRTNGNPAA
LAPALRNEVQQIDTDLPLFDMMTLAERFGKQRWYLSVFGTVFLIFAIIATAMAAVGIYAVMAQAANGRTREIGVRMALGA
DEGSILALVLSRGVKQLGTGMVLGLAAALAVCRLMAKLLFMVSPNDLVTFVAVTLVLGTAGMAAIFFPARRAARLDPLKA
LRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 87099; Mature: 86968

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVQDVRFACRIIRKNPWFSAAIVATLAFGMGVNTTVFSLVNAVLYKPLPFRGGERLVM
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEE
AYAVNRSNGENTMPVSYADYRNFRDESHSFERLELFDSLAVNLGERGNPPERFRGGRISA
EEEEECCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCH
GMFDMLATHPVLGRGMSPADEKAGAPQVVLLGYGVWRDRYGKDPGVLGRAVRVNEKPAVI
HHHHHHHCCHHHCCCCCCCHHHCCCCEEEEEECHHHHHHCCCCCCCCCCEEEECCCCEEE
IGVMPEGFKFPNNEDLWLAAIPDAAAEKRSNRDYRMIGMLKPGIPITEARADLGAIAKRL
EEECCCCCCCCCCCCEEEEECCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
AQAYPETNKDHGATVLTFHDAMNGGPIRLVFLLMMGAVGFVLLIACANVANMLLSRAVER
HHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TREVSIRTAMGAGRWRLVGQMLIESVLLASLGGLLGLVLARAGISAFGRAVADVGKPYWI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
DFSMDYVVFAYFGALTILTGLLFGLAPALAATRVNLNDALKDGSRGSSGGSGYLSGALVI
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHH
LQFTLSVVLLSGAGLMMRSFLLAQSEFGGMNADKVLVARVRLPQDRYPKDADRQRFFDKL
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
MPRVAALPGVSASAMVSDLPGDGSATRRFEIAGRPITEARRLPAASVVMANTGYLQLLGL
HHHHHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEEECCCHHHHHHH
TLLRGRDFEATDGLPGKETVIVSQTMAARFFPNQDPVGRQLRVYKDDDKPQAWMTIIGVA
HHHCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECC
PDFRQKNPSDPADDPVLLVPYRFDSYSSMALMLRTNGNPAALAPALRNEVQQIDTDLPLF
CCHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHH
DMMTLAERFGKQRWYLSVFGTVFLIFAIIATAMAAVGIYAVMAQAANGRTREIGVRMALG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
ADEGSILALVLSRGVKQLGTGMVLGLAAALAVCRLMAKLLFMVSPNDLVTFVAVTLVLGT
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
AGMAAIFFPARRAARLDPLKALRYE
CCHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
SLVQDVRFACRIIRKNPWFSAAIVATLAFGMGVNTTVFSLVNAVLYKPLPFRGGERLVM
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEE
AYAVNRSNGENTMPVSYADYRNFRDESHSFERLELFDSLAVNLGERGNPPERFRGGRISA
EEEEECCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCH
GMFDMLATHPVLGRGMSPADEKAGAPQVVLLGYGVWRDRYGKDPGVLGRAVRVNEKPAVI
HHHHHHHCCHHHCCCCCCCHHHCCCCEEEEEECHHHHHHCCCCCCCCCCEEEECCCCEEE
IGVMPEGFKFPNNEDLWLAAIPDAAAEKRSNRDYRMIGMLKPGIPITEARADLGAIAKRL
EEECCCCCCCCCCCCEEEEECCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
AQAYPETNKDHGATVLTFHDAMNGGPIRLVFLLMMGAVGFVLLIACANVANMLLSRAVER
HHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TREVSIRTAMGAGRWRLVGQMLIESVLLASLGGLLGLVLARAGISAFGRAVADVGKPYWI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
DFSMDYVVFAYFGALTILTGLLFGLAPALAATRVNLNDALKDGSRGSSGGSGYLSGALVI
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHH
LQFTLSVVLLSGAGLMMRSFLLAQSEFGGMNADKVLVARVRLPQDRYPKDADRQRFFDKL
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
MPRVAALPGVSASAMVSDLPGDGSATRRFEIAGRPITEARRLPAASVVMANTGYLQLLGL
HHHHHHCCCCCHHHHHHCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEEECCCHHHHHHH
TLLRGRDFEATDGLPGKETVIVSQTMAARFFPNQDPVGRQLRVYKDDDKPQAWMTIIGVA
HHHCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECC
PDFRQKNPSDPADDPVLLVPYRFDSYSSMALMLRTNGNPAALAPALRNEVQQIDTDLPLF
CCHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHH
DMMTLAERFGKQRWYLSVFGTVFLIFAIIATAMAAVGIYAVMAQAANGRTREIGVRMALG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
ADEGSILALVLSRGVKQLGTGMVLGLAAALAVCRLMAKLLFMVSPNDLVTFVAVTLVLGT
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
AGMAAIFFPARRAARLDPLKALRYE
CCHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA