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The map label for this gene is appB [H]

Identifier: 116622560

GI number: 116622560

Start: 4374588

End: 4375550

Strand: Reverse

Name: appB [H]

Synonym: Acid_3458

Alternate gene names: 116622560

Gene position: 4375550-4374588 (Counterclockwise)

Preceding gene: 116622561

Following gene: 116622559

Centisome position: 43.91

GC content: 66.46

Gene sequence:

>963_bases
ATGAAATACGCAATCCGCCGGCTGTTGCACAGCGTGTTGCTGTTGGGGGCGCTCTCGGTGCTCTCGTTCCTTTTCGCCGA
TTTCGCGCCGGGCGATTTCTATTCGGAAATGCGGTTCAATCCGCGGATCTCCGCCGGGACGATTGAGGCGATGCGGGCTG
AGCGGGGACTGGACCGTCCGCTGCCGGCGCGGTACGCGGCCTGGCTGGGTTCGGTGGCGCGCGGAGAGTTCGGGTACTCG
CTGGCGTACAGTGCGCCGGTCGGACCGCTCATCTGGCAGCGAATTCCGGGGACATTGACGCTGACCATGACGGCCACGCT
AGCGGCGTGGCTGCTGGCCGTCCCGCTGGGTATCTGGAACGCGTCGCGGCGCGGATCGTGGAGCGACTCACTAACTAAAG
CTATTCTTTCAGTCCTGATGGCTATTCCCGACATATTACTCGCAGTTGTCTTCCTGGTGCTGGCCGTGGAAAGCGGCTGG
CTGCCGGCCGGCGGAATGCACTCTCCGGGCGCGGAAGGCTGGAGCGCGGCGCAGCGCTTCGGCGACACTTTGCGCCACCT
GGTGGTGCCGGTCGCGGTGCTGGTTCTGGGCATGCTGCCGGTGCTCACCCGGCATGTCCGCGCCGCGATGGTGGAGGCGC
TGGATGCGCCGTTTGCGCTGGCGGCCCGGGCGCACGGCATCCCGCGGCGGCGGATTTTGTTCCGGCACGTTCTGCCGGCG
GCGCTCAATCCGCTGGTCACGCTGTTTGGATTTTCCCTGGGCACGCTGTTGAGCGCGTCGCTGCTGATCGAGGTGATCGT
GGGCTGGCCGGGGCTGGGGCCGCTGTTCCTGGAGGCGATCCTGGCGCGCGATTTCGCGCTGGTGCTGGGCGTGGTGATGG
TCTCGGCAACGCTGCTGATTAGCGGCAACCTGGCGGCCGACCTGCTGCTCTATCGCGCGGACCCGAGGATTCGTACGCGA
TGA

Upstream 100 bases:

>100_bases
AAGCGGGACGGATCGTCGAGATGGCGGCCACTCAAGAGTTGATGACCGCGCCGCGCCATCCGCACACGCAGGAGCTGATC
GCGGCCACGGCGGCTCTGCG

Downstream 100 bases:

>100_bases
TGCAAGGTCAAGGAGAGGGGCGGCCGCGGGGGCAGCGGGGCGAGCCGGCTGAAAGCCGGCTGCAGGCAGGATTGCCTGCC
CCACATTGCGGCAAGCCGCA

Product: binding-protein-dependent transporter inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKYAIRRLLHSVLLLGALSVLSFLFADFAPGDFYSEMRFNPRISAGTIEAMRAERGLDRPLPARYAAWLGSVARGEFGYS
LAYSAPVGPLIWQRIPGTLTLTMTATLAAWLLAVPLGIWNASRRGSWSDSLTKAILSVLMAIPDILLAVVFLVLAVESGW
LPAGGMHSPGAEGWSAAQRFGDTLRHLVVPVAVLVLGMLPVLTRHVRAAMVEALDAPFALAARAHGIPRRRILFRHVLPA
ALNPLVTLFGFSLGTLLSASLLIEVIVGWPGLGPLFLEAILARDFALVLGVVMVSATLLISGNLAADLLLYRADPRIRTR

Sequences:

>Translated_320_residues
MKYAIRRLLHSVLLLGALSVLSFLFADFAPGDFYSEMRFNPRISAGTIEAMRAERGLDRPLPARYAAWLGSVARGEFGYS
LAYSAPVGPLIWQRIPGTLTLTMTATLAAWLLAVPLGIWNASRRGSWSDSLTKAILSVLMAIPDILLAVVFLVLAVESGW
LPAGGMHSPGAEGWSAAQRFGDTLRHLVVPVAVLVLGMLPVLTRHVRAAMVEALDAPFALAARAHGIPRRRILFRHVLPA
ALNPLVTLFGFSLGTLLSASLLIEVIVGWPGLGPLFLEAILARDFALVLGVVMVSATLLISGNLAADLLLYRADPRIRTR
>Mature_320_residues
MKYAIRRLLHSVLLLGALSVLSFLFADFAPGDFYSEMRFNPRISAGTIEAMRAERGLDRPLPARYAAWLGSVARGEFGYS
LAYSAPVGPLIWQRIPGTLTLTMTATLAAWLLAVPLGIWNASRRGSWSDSLTKAILSVLMAIPDILLAVVFLVLAVESGW
LPAGGMHSPGAEGWSAAQRFGDTLRHLVVPVAVLVLGMLPVLTRHVRAAMVEALDAPFALAARAHGIPRRRILFRHVLPA
ALNPLVTLFGFSLGTLLSASLLIEVIVGWPGLGPLFLEAILARDFALVLGVVMVSATLLISGNLAADLLLYRADPRIRTR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=321, Percent_Identity=31.1526479750779, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787497, Length=321, Percent_Identity=30.5295950155763, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=30.9734513274336, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1789888, Length=325, Percent_Identity=29.8461538461538, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788504, Length=276, Percent_Identity=30.4347826086957, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=31.306990881459, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=28.3582089552239, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34499; Mature: 34499

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAIRRLLHSVLLLGALSVLSFLFADFAPGDFYSEMRFNPRISAGTIEAMRAERGLDRP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
LPARYAAWLGSVARGEFGYSLAYSAPVGPLIWQRIPGTLTLTMTATLAAWLLAVPLGIWN
CHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCC
ASRRGSWSDSLTKAILSVLMAIPDILLAVVFLVLAVESGWLPAGGMHSPGAEGWSAAQRF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
GDTLRHLVVPVAVLVLGMLPVLTRHVRAAMVEALDAPFALAARAHGIPRRRILFRHVLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHH
ALNPLVTLFGFSLGTLLSASLLIEVIVGWPGLGPLFLEAILARDFALVLGVVMVSATLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGNLAADLLLYRADPRIRTR
CCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKYAIRRLLHSVLLLGALSVLSFLFADFAPGDFYSEMRFNPRISAGTIEAMRAERGLDRP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
LPARYAAWLGSVARGEFGYSLAYSAPVGPLIWQRIPGTLTLTMTATLAAWLLAVPLGIWN
CHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCC
ASRRGSWSDSLTKAILSVLMAIPDILLAVVFLVLAVESGWLPAGGMHSPGAEGWSAAQRF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
GDTLRHLVVPVAVLVLGMLPVLTRHVRAAMVEALDAPFALAARAHGIPRRRILFRHVLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHH
ALNPLVTLFGFSLGTLLSASLLIEVIVGWPGLGPLFLEAILARDFALVLGVVMVSATLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGNLAADLLLYRADPRIRTR
CCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]