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The map label for this gene is comF [H]

Identifier: 116622521

GI number: 116622521

Start: 4325795

End: 4326469

Strand: Reverse

Name: comF [H]

Synonym: Acid_3419

Alternate gene names: 116622521

Gene position: 4326469-4325795 (Counterclockwise)

Preceding gene: 116622530

Following gene: 116622520

Centisome position: 43.41

GC content: 65.48

Gene sequence:

>675_bases
GTGTGCCCCCGCTGCATACAGGCGCCCGAGCCCTTCGAAGCCGAGTTTTATTGCGTCAGCTGCCGGACTCCGTTCCAAAA
CGCCTTTCCTTTGGATGACAACGGGCGCTGCGCATTGTGCCGTAGCGGACTCCGCGGTTTTGACGCGGCCTACGCCTTCG
GAGCTTATGAGGGCGCCCTTCGCCGGCTGATCCATCTCTTCAAGTACGGCAAAATCCGCACGCTGGCGCGCCCGCTGGGC
CGCTTGCTGGCGCGCGCCATGCCGCTCGATGAGCAGTTCGATTGCATCGTTCCTGTGCCGCTCTATTGGCGCCGCCGGAT
CCAGCGAGGCTTTAATCAGGCTGATCTGCTGGCCCGAATCCTCGCTCGCGCGACCGGGATCCCGGTCGTCCGGGCGCTAC
GGCGTGTCCAACCCACGGCGACCCAGGCAGGCCTGAGCAACAGCGCGCGCCGCCGCAATGTGGCCAGCGCGTTCCGCTCG
CGCGGCGTGGCGGGCCGGCGGATTCTGCTGATCGACGACGTGATGACAACGGGGTCCACCGCGACCTCCTGCGCCTTGGC
TCTCAAACGAGCCGGCGCCAAACGAGTTGCGCTCTTAACGGTTGCTCGCGTAGACCGCCGCATGGAAAGCTGGCGGCTCG
CAGCGTCCAATTCCGAGGTGGGGGGAAGAATTTAA

Upstream 100 bases:

>100_bases
CTCAGTAGTACGTTCCACCTCTCACGCCCTTTTTTCCCTTTTCTTTCCCGACAGCTGCCGAGTCTGCGGCGAAGCTCTGC
GCGAGGTCGCCAGATTCCCC

Downstream 100 bases:

>100_bases
TGATGCAGATGGAACGACTGCAAAGACCGGTCCTGGTGCTCAACGCCAGTTACGAACCGATCAATATCTGCGCCGCCCGG
CGCGCCCTGGTTTTGGTCTT

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MCPRCIQAPEPFEAEFYCVSCRTPFQNAFPLDDNGRCALCRSGLRGFDAAYAFGAYEGALRRLIHLFKYGKIRTLARPLG
RLLARAMPLDEQFDCIVPVPLYWRRRIQRGFNQADLLARILARATGIPVVRALRRVQPTATQAGLSNSARRRNVASAFRS
RGVAGRRILLIDDVMTTGSTATSCALALKRAGAKRVALLTVARVDRRMESWRLAASNSEVGGRI

Sequences:

>Translated_224_residues
MCPRCIQAPEPFEAEFYCVSCRTPFQNAFPLDDNGRCALCRSGLRGFDAAYAFGAYEGALRRLIHLFKYGKIRTLARPLG
RLLARAMPLDEQFDCIVPVPLYWRRRIQRGFNQADLLARILARATGIPVVRALRRVQPTATQAGLSNSARRRNVASAFRS
RGVAGRRILLIDDVMTTGSTATSCALALKRAGAKRVALLTVARVDRRMESWRLAASNSEVGGRI
>Mature_224_residues
MCPRCIQAPEPFEAEFYCVSCRTPFQNAFPLDDNGRCALCRSGLRGFDAAYAFGAYEGALRRLIHLFKYGKIRTLARPLG
RLLARAMPLDEQFDCIVPVPLYWRRRIQRGFNQADLLARILARATGIPVVRALRRVQPTATQAGLSNSARRRNVASAFRS
RGVAGRRILLIDDVMTTGSTATSCALALKRAGAKRVALLTVARVDRRMESWRLAASNSEVGGRI

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=113, Percent_Identity=44.2477876106195, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 24870; Mature: 24870

Theoretical pI: Translated: 11.69; Mature: 11.69

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCPRCIQAPEPFEAEFYCVSCRTPFQNAFPLDDNGRCALCRSGLRGFDAAYAFGAYEGAL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHH
RRLIHLFKYGKIRTLARPLGRLLARAMPLDEQFDCIVPVPLYWRRRIQRGFNQADLLARI
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCCCHHHHHHHH
LARATGIPVVRALRRVQPTATQAGLSNSARRRNVASAFRSRGVAGRRILLIDDVMTTGST
HHHHCCCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCH
ATSCALALKRAGAKRVALLTVARVDRRMESWRLAASNSEVGGRI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MCPRCIQAPEPFEAEFYCVSCRTPFQNAFPLDDNGRCALCRSGLRGFDAAYAFGAYEGAL
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHH
RRLIHLFKYGKIRTLARPLGRLLARAMPLDEQFDCIVPVPLYWRRRIQRGFNQADLLARI
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCCCHHHHHHHH
LARATGIPVVRALRRVQPTATQAGLSNSARRRNVASAFRSRGVAGRRILLIDDVMTTGST
HHHHCCCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCH
ATSCALALKRAGAKRVALLTVARVDRRMESWRLAASNSEVGGRI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]