Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 116622421

GI number: 116622421

Start: 4197360

End: 4199867

Strand: Direct

Name: macB [H]

Synonym: Acid_3318

Alternate gene names: 116622421

Gene position: 4197360-4199867 (Clockwise)

Preceding gene: 116622419

Following gene: 116622422

Centisome position: 42.12

GC content: 63.08

Gene sequence:

>2508_bases
ATGGGTAGAGTACTGTTCGATCTCCGGTTTGCCTTACGCAATTTACGCCGAAGTCCCCTCTTTACGCTGGTGGCGATCGC
TTCGCTGGCGCTGGGCATCGGCGCCAATACCGCGATTTTTACGTTAATCGACCAGCTGATGCTGCGCCTCCTGCCGGTCG
CGCAGCCGGAGCAACTGGTGATGATCTGGTCCACGGGTCCGCACATGGGCAACAATCGCGGGCCGCGCGCCGCGTCCTAC
CCGATGTACCAGGATTTCCAGAAGCAGGCGCAGGCATTTTCGAGCGTCTTCTGCCGGTATGGAACACCGGTGTCGGTAGG
TTTCAGCGGGCAGACGGAACGGGTTGACGCCGAGCTGGTGTCGGGCAACTTTTTTCAGGCGCTGGGCGTGCGGCCGGCCC
TCGGACGCGTGTTCTCTCCCGAAGAGGACGATCGAACTTACAAGGGCCATCCCGTGGTGGTGCTGAGTCACGAGTATTGG
ACCAGCCGGTTCGCGGCCGATCCCAAGGTGATCGGGCAGAAGATGCTGGTGGACAACTACCCGATGACGATCGTAGGCGT
ATCCGCGGCGGGCTTCACCGGGCTGGACCCGGCATTTTCTCCTCAGATCCGTGTGCCCGTACAGATGAAGCCGCTGTTGA
CGCCCGGATGGGATTCAATCGGCGACCGGCGCAGTCAATGGATCCAGATCTTCGCGCGAATGAAGCCCGGGTACACGGTC
GCATCGGCGCAGGCCTCGCTGCAACCGCTGTTCTCGCAGATTCTGCGCGAGGAAGTCGTAGCGCCGGAGCTGAAGGATGC
ATCGCAGTATTACCGGGATCGTTTTCTGGCGCGCAAAATCCAGATGGAGCCTGCGGCGAACGGCTATTCGCAGATGCGTC
GCAGTTATTCCACCGCCCTGATCGTGCTGATGTGCATGGTTGGCCTGGTACTGTTGATCGCCTGCTTTAATGTGGCCAAC
CTGCTGATCGCGCGTGCCGTATCCCGGCAGAAAGAGATCGCGGTGCGGCTGGCGGTGGGAGCCTCGCGCTGGCAATTGCT
CCGCCAGCTGCTGATCGAAAGCCTGGTGATGTCGGTCGTGGGCGGCGCGGCGGGTTTGTTCCTGGCTGTGGTGATGATTC
GCGGCCTGCTGCATTTCCTCCCCGGCGACGAAGCCGCCTTGATGCTGCGCGCGGACCCGGATCTCCGCATCCTGGCGTTC
AATGCGGTGCTCGCCCTGGGCACCGGAATCCTCTTCGGGCTGGTGCCGGCGCTGCAGGCCCTGAAGGTGGAGCTGTGGAA
CACGCTCAAGGATGTGGTGGGCACGGTGTCCGGGCGCGGCGGCGGAGTGACGCTGCGCAAGGCTCTGGTGGTGGCGCAAG
TGGCTTTTTCGTTCCTGCTGTTGGCTGGTGCGGGCCTGTTCGTGCGCACCCTGACCAACCTGAAGCAAACCAATGCCGGC
TTTCGGGACCTGGATAACCTGGTGACCTTCCAGATCGACCCTGCGCTGAGCGGTTACTCGGTGCAGCGGCTGCAGGTCTT
CTATAAGCAGCTGCTGGAGAGCGTGCGTTCCACCCCCGGGGTGAAGTCGGCCGGTTTTGCGATGGTGCCAGTGTTGAGCG
GCAACGAGTGGGATTCCACGATGTCCGTGGAAGGGCACACCACGAAGGACGGCGAAGATATCCAGGCATTCATGAACGGC
ATCTCCAACGATTACTGGAAGGCCATGGGAGTGCCGCTGCTCGAAGGGCGGGATTTCAACGATCACGATGCCGGCAAGAA
GATCACGGTGGCGATCGTGAACCGCAAGTTCGCAACCCATTTCTTCGGCGAGAAGAGCGCAATCGGCAGGCATATCGGGT
TCGGGCAGGGGCCGAAGACCAAACTGGATATCGAGATCGTCGGAGTGGCGGAAGACTCGCTGTACGAAGGGCCGCGCGAG
GGCGTGCGCCGGCAGGCCTTCGTGCCGTTCGCTCAATCGGACTACCCGGCGGGCGTTGCTTTCTATGTGCGGACGTCGAT
GGATTCCCGCGCCATGTTCTCCGCGCTGCGGTTGAAGGTGCGGGAACTGGATGCCGCCATGCCGGTGTACCAGATGAAAA
CGGTGGGCCGGCAGTTGGACGAAACGTTGAGCACGGAGCGCATGATCGCGGTGCTTTCGGCGGCATTCGGGATTCTGGCG
ACCTTGCTGGCTGCGATCGGGCTCTATGGCGTGATGGCCTTCGTGGTGGCGCGGCGGACCCGGGAAATTGGGCTGCGCAT
GGCATTGGGTGCGCCGCGGGGCCTGGTGGTGTGGATGGTGATGCGCGAGACCATCGTGCTGGTGGGCGGCGGTTTGGCGC
TGGGCATCCCGGCCAGCCTGCTGGCCAGCCGGTACGTCTCCACCCAGTTGTTCGGCGTCAAGCCGACGGATCTCGGCGCG
GCCGCGGCGGCGCTCTTGATCCTGGCGATAGTGGCGGCAGGCGCGGGCTTCCTCCCGGCGCGGCGCGCCAGTACGATCGA
CCCGATTCAGGCGTTGCGATACGAATAA

Upstream 100 bases:

>100_bases
CAGATCGCGCGTGAAGACGGGAAAAAATATTACATTCTCGAATGCGTCGGATAGAATTTGCAAACTTTTCGGTCTGACCG
TCGTACTTAAGTATTAAGCC

Downstream 100 bases:

>100_bases
TAAGGAGAGCGTCAATGAAATACGTACTGGTTGGATTGCTGCTGGCGATACCGGCGCTGGCGGACTGGCAATGGGAAGGC
CGGGACGAGGCTCGCCGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 835; Mature: 834

Protein sequence:

>835_residues
MGRVLFDLRFALRNLRRSPLFTLVAIASLALGIGANTAIFTLIDQLMLRLLPVAQPEQLVMIWSTGPHMGNNRGPRAASY
PMYQDFQKQAQAFSSVFCRYGTPVSVGFSGQTERVDAELVSGNFFQALGVRPALGRVFSPEEDDRTYKGHPVVVLSHEYW
TSRFAADPKVIGQKMLVDNYPMTIVGVSAAGFTGLDPAFSPQIRVPVQMKPLLTPGWDSIGDRRSQWIQIFARMKPGYTV
ASAQASLQPLFSQILREEVVAPELKDASQYYRDRFLARKIQMEPAANGYSQMRRSYSTALIVLMCMVGLVLLIACFNVAN
LLIARAVSRQKEIAVRLAVGASRWQLLRQLLIESLVMSVVGGAAGLFLAVVMIRGLLHFLPGDEAALMLRADPDLRILAF
NAVLALGTGILFGLVPALQALKVELWNTLKDVVGTVSGRGGGVTLRKALVVAQVAFSFLLLAGAGLFVRTLTNLKQTNAG
FRDLDNLVTFQIDPALSGYSVQRLQVFYKQLLESVRSTPGVKSAGFAMVPVLSGNEWDSTMSVEGHTTKDGEDIQAFMNG
ISNDYWKAMGVPLLEGRDFNDHDAGKKITVAIVNRKFATHFFGEKSAIGRHIGFGQGPKTKLDIEIVGVAEDSLYEGPRE
GVRRQAFVPFAQSDYPAGVAFYVRTSMDSRAMFSALRLKVRELDAAMPVYQMKTVGRQLDETLSTERMIAVLSAAFGILA
TLLAAIGLYGVMAFVVARRTREIGLRMALGAPRGLVVWMVMRETIVLVGGGLALGIPASLLASRYVSTQLFGVKPTDLGA
AAAALLILAIVAAGAGFLPARRASTIDPIQALRYE

Sequences:

>Translated_835_residues
MGRVLFDLRFALRNLRRSPLFTLVAIASLALGIGANTAIFTLIDQLMLRLLPVAQPEQLVMIWSTGPHMGNNRGPRAASY
PMYQDFQKQAQAFSSVFCRYGTPVSVGFSGQTERVDAELVSGNFFQALGVRPALGRVFSPEEDDRTYKGHPVVVLSHEYW
TSRFAADPKVIGQKMLVDNYPMTIVGVSAAGFTGLDPAFSPQIRVPVQMKPLLTPGWDSIGDRRSQWIQIFARMKPGYTV
ASAQASLQPLFSQILREEVVAPELKDASQYYRDRFLARKIQMEPAANGYSQMRRSYSTALIVLMCMVGLVLLIACFNVAN
LLIARAVSRQKEIAVRLAVGASRWQLLRQLLIESLVMSVVGGAAGLFLAVVMIRGLLHFLPGDEAALMLRADPDLRILAF
NAVLALGTGILFGLVPALQALKVELWNTLKDVVGTVSGRGGGVTLRKALVVAQVAFSFLLLAGAGLFVRTLTNLKQTNAG
FRDLDNLVTFQIDPALSGYSVQRLQVFYKQLLESVRSTPGVKSAGFAMVPVLSGNEWDSTMSVEGHTTKDGEDIQAFMNG
ISNDYWKAMGVPLLEGRDFNDHDAGKKITVAIVNRKFATHFFGEKSAIGRHIGFGQGPKTKLDIEIVGVAEDSLYEGPRE
GVRRQAFVPFAQSDYPAGVAFYVRTSMDSRAMFSALRLKVRELDAAMPVYQMKTVGRQLDETLSTERMIAVLSAAFGILA
TLLAAIGLYGVMAFVVARRTREIGLRMALGAPRGLVVWMVMRETIVLVGGGLALGIPASLLASRYVSTQLFGVKPTDLGA
AAAALLILAIVAAGAGFLPARRASTIDPIQALRYE
>Mature_834_residues
GRVLFDLRFALRNLRRSPLFTLVAIASLALGIGANTAIFTLIDQLMLRLLPVAQPEQLVMIWSTGPHMGNNRGPRAASYP
MYQDFQKQAQAFSSVFCRYGTPVSVGFSGQTERVDAELVSGNFFQALGVRPALGRVFSPEEDDRTYKGHPVVVLSHEYWT
SRFAADPKVIGQKMLVDNYPMTIVGVSAAGFTGLDPAFSPQIRVPVQMKPLLTPGWDSIGDRRSQWIQIFARMKPGYTVA
SAQASLQPLFSQILREEVVAPELKDASQYYRDRFLARKIQMEPAANGYSQMRRSYSTALIVLMCMVGLVLLIACFNVANL
LIARAVSRQKEIAVRLAVGASRWQLLRQLLIESLVMSVVGGAAGLFLAVVMIRGLLHFLPGDEAALMLRADPDLRILAFN
AVLALGTGILFGLVPALQALKVELWNTLKDVVGTVSGRGGGVTLRKALVVAQVAFSFLLLAGAGLFVRTLTNLKQTNAGF
RDLDNLVTFQIDPALSGYSVQRLQVFYKQLLESVRSTPGVKSAGFAMVPVLSGNEWDSTMSVEGHTTKDGEDIQAFMNGI
SNDYWKAMGVPLLEGRDFNDHDAGKKITVAIVNRKFATHFFGEKSAIGRHIGFGQGPKTKLDIEIVGVAEDSLYEGPREG
VRRQAFVPFAQSDYPAGVAFYVRTSMDSRAMFSALRLKVRELDAAMPVYQMKTVGRQLDETLSTERMIAVLSAAFGILAT
LLAAIGLYGVMAFVVARRTREIGLRMALGAPRGLVVWMVMRETIVLVGGGLALGIPASLLASRYVSTQLFGVKPTDLGAA
AAALLILAIVAAGAGFLPARRASTIDPIQALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=297, Percent_Identity=27.9461279461279, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 90866; Mature: 90735

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRVLFDLRFALRNLRRSPLFTLVAIASLALGIGANTAIFTLIDQLMLRLLPVAQPEQLV
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEE
MIWSTGPHMGNNRGPRAASYPMYQDFQKQAQAFSSVFCRYGTPVSVGFSGQTERVDAELV
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHH
SGNFFQALGVRPALGRVFSPEEDDRTYKGHPVVVLSHEYWTSRFAADPKVIGQKMLVDNY
CCCHHHHHCCCHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHCCCHHHHHHHHHHCCC
PMTIVGVSAAGFTGLDPAFSPQIRVPVQMKPLLTPGWDSIGDRRSQWIQIFARMKPGYTV
CEEEEEECCCCCCCCCCCCCCCEECCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
ASAQASLQPLFSQILREEVVAPELKDASQYYRDRFLARKIQMEPAANGYSQMRRSYSTAL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IVLMCMVGLVLLIACFNVANLLIARAVSRQKEIAVRLAVGASRWQLLRQLLIESLVMSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHH
GGAAGLFLAVVMIRGLLHFLPGDEAALMLRADPDLRILAFNAVLALGTGILFGLVPALQA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
LKVELWNTLKDVVGTVSGRGGGVTLRKALVVAQVAFSFLLLAGAGLFVRTLTNLKQTNAG
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
FRDLDNLVTFQIDPALSGYSVQRLQVFYKQLLESVRSTPGVKSAGFAMVPVLSGNEWDST
HHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCE
MSVEGHTTKDGEDIQAFMNGISNDYWKAMGVPLLEGRDFNDHDAGKKITVAIVNRKFATH
EEECCCCCCCHHHHHHHHHHHCCHHHHHHCCCEECCCCCCCCCCCCEEEEEEECCHHHHH
FFGEKSAIGRHIGFGQGPKTKLDIEIVGVAEDSLYEGPREGVRRQAFVPFAQSDYPAGVA
HCCCHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHCCHHHHHHHHHCCCCCCCCCCCCEE
FYVRTSMDSRAMFSALRLKVRELDAAMPVYQMKTVGRQLDETLSTERMIAVLSAAFGILA
EEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLAAIGLYGVMAFVVARRTREIGLRMALGAPRGLVVWMVMRETIVLVGGGLALGIPASL
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHEEECCCHHHCCCHHH
LASRYVSTQLFGVKPTDLGAAAAALLILAIVAAGAGFLPARRASTIDPIQALRYE
HHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
GRVLFDLRFALRNLRRSPLFTLVAIASLALGIGANTAIFTLIDQLMLRLLPVAQPEQLV
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEE
MIWSTGPHMGNNRGPRAASYPMYQDFQKQAQAFSSVFCRYGTPVSVGFSGQTERVDAELV
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHH
SGNFFQALGVRPALGRVFSPEEDDRTYKGHPVVVLSHEYWTSRFAADPKVIGQKMLVDNY
CCCHHHHHCCCHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHCCCHHHHHHHHHHCCC
PMTIVGVSAAGFTGLDPAFSPQIRVPVQMKPLLTPGWDSIGDRRSQWIQIFARMKPGYTV
CEEEEEECCCCCCCCCCCCCCCEECCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
ASAQASLQPLFSQILREEVVAPELKDASQYYRDRFLARKIQMEPAANGYSQMRRSYSTAL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
IVLMCMVGLVLLIACFNVANLLIARAVSRQKEIAVRLAVGASRWQLLRQLLIESLVMSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHH
GGAAGLFLAVVMIRGLLHFLPGDEAALMLRADPDLRILAFNAVLALGTGILFGLVPALQA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
LKVELWNTLKDVVGTVSGRGGGVTLRKALVVAQVAFSFLLLAGAGLFVRTLTNLKQTNAG
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
FRDLDNLVTFQIDPALSGYSVQRLQVFYKQLLESVRSTPGVKSAGFAMVPVLSGNEWDST
HHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCE
MSVEGHTTKDGEDIQAFMNGISNDYWKAMGVPLLEGRDFNDHDAGKKITVAIVNRKFATH
EEECCCCCCCHHHHHHHHHHHCCHHHHHHCCCEECCCCCCCCCCCCEEEEEEECCHHHHH
FFGEKSAIGRHIGFGQGPKTKLDIEIVGVAEDSLYEGPREGVRRQAFVPFAQSDYPAGVA
HCCCHHHHHHHCCCCCCCCCEEEEEEEEECCHHHHCCHHHHHHHHHCCCCCCCCCCCCEE
FYVRTSMDSRAMFSALRLKVRELDAAMPVYQMKTVGRQLDETLSTERMIAVLSAAFGILA
EEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLAAIGLYGVMAFVVARRTREIGLRMALGAPRGLVVWMVMRETIVLVGGGLALGIPASL
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHEEECCCHHHCCCHHH
LASRYVSTQLFGVKPTDLGAAAAALLILAIVAAGAGFLPARRASTIDPIQALRYE
HHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA