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The map label for this gene is ykfC [H]

Identifier: 116622418

GI number: 116622418

Start: 4192968

End: 4194356

Strand: Direct

Name: ykfC [H]

Synonym: Acid_3314

Alternate gene names: 116622418

Gene position: 4192968-4194356 (Clockwise)

Preceding gene: 116622416

Following gene: 116622419

Centisome position: 42.07

GC content: 57.88

Gene sequence:

>1389_bases
ATGAGTCTCAAGGACGACAAGCAGCAGAACATCCAGATGCAACTGGACTTCTCTTCTGTGCTAACGGGTGAAGCCCGAGA
GGCGGGAAGGGAAGAGACTGAATCGGCCGGGGCGATGAATGGGACCGAAAACCCAGCCAGCACGAATCGATTGATGGAGG
AAGTATGTGAGCGAGAAAACCTGAAGGCAGCATTGCAGCGGGTGAAGGCCAACAAAGGTAGTCCGGGCGTTGACGGGATG
ACCGTCATCGGCATCAAGGATTACCTGAAGCAGCACTGGCCAGCCATCCGGGGACAACTGTTGAGTGGGACTTACGAGCC
GAAACCGGTGAGGCGGGTAGAGATTGCCAAACCGGACGGAGGGGTGCGAAAGCTTGGTATCCCAACGGTGTTGGATCGAT
TTATCCAGCAGGCGGTGATGCAGGTTCTGCAGAGGCGGTGGGACCGGACGTTTTCTGATTACAGCTACGGGTTCCGGCCG
GGACGGTCGGCTCAGCAAGCGGTGGCACAGGCGCAGCAGTATATTGCCGAAGGTCACGGCTGGTGCGTTGATCTTGATTT
GGAGAAATTCTTCGATCGAGTCAATCACGACAAATTGATGGGTCAGATCGCCAAACGGATCGCGGACAAGCGGCTGCTGA
AACTCATCCGGGCATTCTTGAATGCCGGGGTGATGGAGAACGGGTTGGTCAGCCCGAGCGTGGAAGGAACTCCGCAAGGA
GGTCCTCTTTCGCCACTGCTCAGTAACCTCGTGCTCGACGAATTCGACCGGGAGTTGGAGCGCCGGGGTCATCGCTTCGT
TCGATATGCGGACGACTGTAATATCTACGTTCGCAGCGAGCGGGCGGGGCAACGAGTGATGGAGAGCATTACGCAATTCA
TCACGCAAAAGCTCAAGCTCAAGGTAAATGAGACGAAGAGTGCGGTGGCACGACCGCAGGAACGGAAGTTTCTCGGGTTC
AGCTTTACGGCTGGTCCGGAGGCCAAGCGCGTGATTGCACCGAAGGCCTTGGATCGGTTTAAGCGACGAATCCGGGAGAT
CACGGGACGGGCAAAGGGCGTTAGCATGAAGACGACGATGGAGGAACTGGCTCCGTATATGCGGGGTTGGCGCAGCTATT
TCGGATTCTGCGAAACGCCCGAGGTGCTGATCGGTTTAACGCGCTGGGTCCGGTTGCGACTCCGGGCGGCCATGTGGCGG
CAGTGGAAAACACCGCGCCGTCGCCGGGCAGCTCTGTTGGAACTGGGGGTGCGAGAGCGGCTGGCGACTAATACCGCTGG
CAGCGGTCGCGGTCCTTGGTACCTCGCGAAGGCCAAGGCCCTGGCTGTTGGGCTTTCAAATGCTTACTTCAAATCGCTGG
GACTTCCGTCATTGTTCGAGGACTGTTAG

Upstream 100 bases:

>100_bases
GGCTAGTGAGGCACTCCGCATGCCGAAAGGCGGAGCAACGGATAGGCCAAGCCGGGAACGATGGCTGAAGGCCCGAACGA
GAAGGAGCGGCCAGTAGGCC

Downstream 100 bases:

>100_bases
CGTAACCATCTCGAACCGCCGTGTACGGACCCGTACGCACGGTGGTGTGGCAGGGGTCGGCGGGTGACCGCCGCCCCTAT
GCCGATCAAACGCGCTTGGG

Product: RNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSLKDDKQQNIQMQLDFSSVLTGEAREAGREETESAGAMNGTENPASTNRLMEEVCERENLKAALQRVKANKGSPGVDGM
TVIGIKDYLKQHWPAIRGQLLSGTYEPKPVRRVEIAKPDGGVRKLGIPTVLDRFIQQAVMQVLQRRWDRTFSDYSYGFRP
GRSAQQAVAQAQQYIAEGHGWCVDLDLEKFFDRVNHDKLMGQIAKRIADKRLLKLIRAFLNAGVMENGLVSPSVEGTPQG
GPLSPLLSNLVLDEFDRELERRGHRFVRYADDCNIYVRSERAGQRVMESITQFITQKLKLKVNETKSAVARPQERKFLGF
SFTAGPEAKRVIAPKALDRFKRRIREITGRAKGVSMKTTMEELAPYMRGWRSYFGFCETPEVLIGLTRWVRLRLRAAMWR
QWKTPRRRRAALLELGVRERLATNTAGSGRGPWYLAKAKALAVGLSNAYFKSLGLPSLFEDC

Sequences:

>Translated_462_residues
MSLKDDKQQNIQMQLDFSSVLTGEAREAGREETESAGAMNGTENPASTNRLMEEVCERENLKAALQRVKANKGSPGVDGM
TVIGIKDYLKQHWPAIRGQLLSGTYEPKPVRRVEIAKPDGGVRKLGIPTVLDRFIQQAVMQVLQRRWDRTFSDYSYGFRP
GRSAQQAVAQAQQYIAEGHGWCVDLDLEKFFDRVNHDKLMGQIAKRIADKRLLKLIRAFLNAGVMENGLVSPSVEGTPQG
GPLSPLLSNLVLDEFDRELERRGHRFVRYADDCNIYVRSERAGQRVMESITQFITQKLKLKVNETKSAVARPQERKFLGF
SFTAGPEAKRVIAPKALDRFKRRIREITGRAKGVSMKTTMEELAPYMRGWRSYFGFCETPEVLIGLTRWVRLRLRAAMWR
QWKTPRRRRAALLELGVRERLATNTAGSGRGPWYLAKAKALAVGLSNAYFKSLGLPSLFEDC
>Mature_461_residues
SLKDDKQQNIQMQLDFSSVLTGEAREAGREETESAGAMNGTENPASTNRLMEEVCERENLKAALQRVKANKGSPGVDGMT
VIGIKDYLKQHWPAIRGQLLSGTYEPKPVRRVEIAKPDGGVRKLGIPTVLDRFIQQAVMQVLQRRWDRTFSDYSYGFRPG
RSAQQAVAQAQQYIAEGHGWCVDLDLEKFFDRVNHDKLMGQIAKRIADKRLLKLIRAFLNAGVMENGLVSPSVEGTPQGG
PLSPLLSNLVLDEFDRELERRGHRFVRYADDCNIYVRSERAGQRVMESITQFITQKLKLKVNETKSAVARPQERKFLGFS
FTAGPEAKRVIAPKALDRFKRRIREITGRAKGVSMKTTMEELAPYMRGWRSYFGFCETPEVLIGLTRWVRLRLRAAMWRQ
WKTPRRRRAALLELGVRERLATNTAGSGRGPWYLAKAKALAVGLSNAYFKSLGLPSLFEDC

Specific function: Unknown

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226521, Length=280, Percent_Identity=28.9285714285714, Blast_Score=126, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6226520, Length=329, Percent_Identity=26.1398176291793, Blast_Score=120, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015706
- InterPro:   IPR000477 [H]

Pfam domain/function: PF00078 RVT_1 [H]

EC number: NA

Molecular weight: Translated: 52312; Mature: 52181

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKDDKQQNIQMQLDFSSVLTGEAREAGREETESAGAMNGTENPASTNRLMEEVCEREN
CCCCCCCCCCCEEEEEHHHHHCCHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LKAALQRVKANKGSPGVDGMTVIGIKDYLKQHWPAIRGQLLSGTYEPKPVRRVEIAKPDG
HHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEECCCC
GVRKLGIPTVLDRFIQQAVMQVLQRRWDRTFSDYSYGFRPGRSAQQAVAQAQQYIAEGHG
CCEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
WCVDLDLEKFFDRVNHDKLMGQIAKRIADKRLLKLIRAFLNAGVMENGLVSPSVEGTPQG
EEEEECHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GPLSPLLSNLVLDEFDRELERRGHRFVRYADDCNIYVRSERAGQRVMESITQFITQKLKL
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHH
KVNETKSAVARPQERKFLGFSFTAGPEAKRVIAPKALDRFKRRIREITGRAKGVSMKTTM
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHH
EELAPYMRGWRSYFGFCETPEVLIGLTRWVRLRLRAAMWRQWKTPRRRRAALLELGVRER
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LATNTAGSGRGPWYLAKAKALAVGLSNAYFKSLGLPSLFEDC
HHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure 
SLKDDKQQNIQMQLDFSSVLTGEAREAGREETESAGAMNGTENPASTNRLMEEVCEREN
CCCCCCCCCCEEEEEHHHHHCCHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LKAALQRVKANKGSPGVDGMTVIGIKDYLKQHWPAIRGQLLSGTYEPKPVRRVEIAKPDG
HHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEECCCC
GVRKLGIPTVLDRFIQQAVMQVLQRRWDRTFSDYSYGFRPGRSAQQAVAQAQQYIAEGHG
CCEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
WCVDLDLEKFFDRVNHDKLMGQIAKRIADKRLLKLIRAFLNAGVMENGLVSPSVEGTPQG
EEEEECHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GPLSPLLSNLVLDEFDRELERRGHRFVRYADDCNIYVRSERAGQRVMESITQFITQKLKL
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHH
KVNETKSAVARPQERKFLGFSFTAGPEAKRVIAPKALDRFKRRIREITGRAKGVSMKTTM
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHH
EELAPYMRGWRSYFGFCETPEVLIGLTRWVRLRLRAAMWRQWKTPRRRRAALLELGVRER
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LATNTAGSGRGPWYLAKAKALAVGLSNAYFKSLGLPSLFEDC
HHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]