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The map label for this gene is lpxA [H]

Identifier: 116621970

GI number: 116621970

Start: 3614419

End: 3615207

Strand: Direct

Name: lpxA [H]

Synonym: Acid_2855

Alternate gene names: 116621970

Gene position: 3614419-3615207 (Clockwise)

Preceding gene: 116621969

Following gene: 116621971

Centisome position: 36.27

GC content: 61.72

Gene sequence:

>789_bases
ATGCCCATCGACTCTTCCGCCGTCGTCGCCCACACAGCGCGCGTCTCGCCTGAAGCCTCCATCGGCCCGGGAGTCCGCAT
CGGCGAATTCTGCGTCGTCGAATCAGACGTCGTCCTCGGTGCCGGCTGTATCCTCGAACCCCACGTCTACATCAAGCGCT
GGACCACCCTCGGTGAACGCAATGAAATCTCCGCCGGCGCCGTGCTCGGCACCGACCCGCTCGACAAGAATTTCAAAGGC
GAGCGCAGCTATCTCACCATCGGCAACGGCAATAAGATCCGCGAACACTTCACCATCTCGCGCGGTACTCCTCCCGAATC
CGCCACCACCATTGGGGATGATAACTTCATCATGACCAGCGGACACATCGCCCACAACTGCAAAATCGGCAGTAATACGG
TTATTGCCAGTTGTGCCCTGCTCGGCGGCTATGTCGAAGTCGAGGATCACGCCTTCCTCTCCGGCGGCGTCCTCGTCCAT
CAATATTCCAAGGTGGGCCGCCTCGCCATGGTCAGCGGCAACACTCGCGTCAACCTCGATGCGCCGCCTTTTTTCACCTT
CGCCGGCTTCGCCATCGCGCCCAAGGGCCTGAACCTCGTCGGCCTCAAGCGCGCCGGCTTCGACGCCCCGCGCATCAGTA
TCCTCAAACAGGCCTACCGCTATCTCTATCGCTCCAACCTCAAACTCGACGCCGCCCTCGCGCGCATCGAGGACGAAATC
CCCACTCCCGATACCCTCCACCTGACCGCCTTCATCCGATCCAGCCGTCGTGGCGTCTGCCGCGAATGA

Upstream 100 bases:

>100_bases
GATGGTTCGCCCGAGCCCTCCACCTTCATCCTGTTCGCCACCGGCGCCGCCCTGCTCGCCGGGCGCAGCCGCCGCGCTAA
TGGGCTTATGATACGAAATC

Downstream 100 bases:

>100_bases
GCTGCGCGGATGTTACAATTCTGCGGTGCGGATCCCGCTCATCCTGGCCTGCGCTCTTGGCATCGCGGTCAATTGCTTTC
TGTACCGCCCCGTGCTCGGC

Product: acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPIDSSAVVAHTARVSPEASIGPGVRIGEFCVVESDVVLGAGCILEPHVYIKRWTTLGERNEISAGAVLGTDPLDKNFKG
ERSYLTIGNGNKIREHFTISRGTPPESATTIGDDNFIMTSGHIAHNCKIGSNTVIASCALLGGYVEVEDHAFLSGGVLVH
QYSKVGRLAMVSGNTRVNLDAPPFFTFAGFAIAPKGLNLVGLKRAGFDAPRISILKQAYRYLYRSNLKLDAALARIEDEI
PTPDTLHLTAFIRSSRRGVCRE

Sequences:

>Translated_262_residues
MPIDSSAVVAHTARVSPEASIGPGVRIGEFCVVESDVVLGAGCILEPHVYIKRWTTLGERNEISAGAVLGTDPLDKNFKG
ERSYLTIGNGNKIREHFTISRGTPPESATTIGDDNFIMTSGHIAHNCKIGSNTVIASCALLGGYVEVEDHAFLSGGVLVH
QYSKVGRLAMVSGNTRVNLDAPPFFTFAGFAIAPKGLNLVGLKRAGFDAPRISILKQAYRYLYRSNLKLDAALARIEDEI
PTPDTLHLTAFIRSSRRGVCRE
>Mature_261_residues
PIDSSAVVAHTARVSPEASIGPGVRIGEFCVVESDVVLGAGCILEPHVYIKRWTTLGERNEISAGAVLGTDPLDKNFKGE
RSYLTIGNGNKIREHFTISRGTPPESATTIGDDNFIMTSGHIAHNCKIGSNTVIASCALLGGYVEVEDHAFLSGGVLVHQ
YSKVGRLAMVSGNTRVNLDAPPFFTFAGFAIAPKGLNLVGLKRAGFDAPRISILKQAYRYLYRSNLKLDAALARIEDEIP
TPDTLHLTAFIRSSRRGVCRE

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=261, Percent_Identity=39.0804597701149, Blast_Score=174, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28225; Mature: 28093

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDSSAVVAHTARVSPEASIGPGVRIGEFCVVESDVVLGAGCILEPHVYIKRWTTLGER
CCCCCCEEEEEEEECCCCCCCCCCCEECEEEEEECCEEEECCEEECCCEEEEEEECCCCC
NEISAGAVLGTDPLDKNFKGERSYLTIGNGNKIREHFTISRGTPPESATTIGDDNFIMTS
CCCCCCEEEECCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCCEEECCCCEEEEC
GHIAHNCKIGSNTVIASCALLGGYVEVEDHAFLSGGVLVHQYSKVGRLAMVSGNTRVNLD
CCEEEEEEECCCHHEEHHHHHCCEEEECCCEEEECCEEEEEHHCCCEEEEEECCEEEEEC
APPFFTFAGFAIAPKGLNLVGLKRAGFDAPRISILKQAYRYLYRSNLKLDAALARIEDEI
CCCCEEECCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
PTPDTLHLTAFIRSSRRGVCRE
CCCCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
PIDSSAVVAHTARVSPEASIGPGVRIGEFCVVESDVVLGAGCILEPHVYIKRWTTLGER
CCCCCEEEEEEEECCCCCCCCCCCEECEEEEEECCEEEECCEEECCCEEEEEEECCCCC
NEISAGAVLGTDPLDKNFKGERSYLTIGNGNKIREHFTISRGTPPESATTIGDDNFIMTS
CCCCCCEEEECCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCCEEECCCCEEEEC
GHIAHNCKIGSNTVIASCALLGGYVEVEDHAFLSGGVLVHQYSKVGRLAMVSGNTRVNLD
CCEEEEEEECCCHHEEHHHHHCCEEEECCCEEEECCEEEEEHHCCCEEEEEECCEEEEEC
APPFFTFAGFAIAPKGLNLVGLKRAGFDAPRISILKQAYRYLYRSNLKLDAALARIEDEI
CCCCEEECCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
PTPDTLHLTAFIRSSRRGVCRE
CCCCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA