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The map label for this gene is argD [H]

Identifier: 116621837

GI number: 116621837

Start: 3446452

End: 3447672

Strand: Direct

Name: argD [H]

Synonym: Acid_2719

Alternate gene names: 116621837

Gene position: 3446452-3447672 (Clockwise)

Preceding gene: 116621836

Following gene: 116621838

Centisome position: 34.58

GC content: 62.65

Gene sequence:

>1221_bases
ATGACGACTGCCTTGCCCCCTGTTCAGGACACTCTCGCCCAACCGATTATGGACCTGGAGCGCGAATATCTGCTGCAGAA
CTATGCGCGGTATCCGCTCGTACTGGCCCGCGGGAAGGGCTGCTACCTTTATGACCTGGCGGGCAAGCGATACCTGGACC
TGATTTCCGGGATCGGCGTCAATGCGCTGGGCCACGCGCATCCGCGGATCACCAAAGTGATCCGCGCGCAGGCCGCCCTT
TTGCTGCACACTTCCAACCTCTATTACCACGAGTATCAGGGCGCGCTGGCGAAGCGGCTGGCGCAGATGAGCGGATTGCA
GCGCTGCTTCTTCAGCAATACCGGGACGGAGGCGGTGGAGGGCGCGCTCAAGATGGCGCACTCGCATGGGCGCGCGATTC
ACTCCGACAAGTACGAGGTAATCGCGCTGGATAATTCCTTCCACGGGCGGACCTTGGGCGCGCTTTCGATTACGGGGCAG
GCCAAGTACCGCCAGGATTTCGAACCGCTGGTGCCGGGCGCGCGCTTCGTGCCGGCTAACGATATCGCCGCGCTGGAAGG
GGCGTTCAGCGAACGCACGGCGGCGATCGTGCTCGAAATGATCCAGGGCGAGGGCGGGATCAACCCGCTGAGCCCGGAGT
ACGTGGTGAAGGCGAGGGAGCTTGCCGACCGCTATAACGCGCTGCTGGTGTTGGACGAAACGCAGTGCGGCGTGGGACGG
CCGGGCACCTATTTTTCCTATCAGCGCTCCAGCCATATCACGATGCCGGACGTGATGGTGAGCGCGAAGCCGCTGGCTTG
CGGGATTCCGCTTGGCGTGATCATGGCCAACGAGCGGGCGGCGGCGGCGATCAAACCCGGGATGCACGGGTCCACATTTG
GCGGCGGACCGCTGGCCTGCCGGGTGGCGCTGGAATTCTGCGACATCCTGGACGAGCTGCTGCCCTCGATTCAGCGCGTG
GGCGGCTACCTGCACGTGGAGCTCAATGAACTGGCGCGCAAGCACTCATTCATCAAGGAAGTGCGCGGGTTCGGGCTGAT
GATCGGCGTGGAGCTGGCCATGCCGGGCAAGCAACTGGTGCTGGATGCGATGGCACAGGGGCTGCTCATCAATTGCACGC
ACGATACGGTACTGCGCTTCCTGCCGCCTTATATCATCACCGAGAAGGAAGTGGATCTGGCGGTGCGGACGCTCGGGAAA
ATATTTTCCAGGGTGAAATAA

Upstream 100 bases:

>100_bases
GAAAGCAATGTGGGCCGCAGATGAACGCGGATAAGTAAAAACTGCTCGACATGAGGCATGTGGCTCTGGGAGGGTGAGTG
GGGCGCGGTATTATTGTGAA

Downstream 100 bases:

>100_bases
ATGCACCGTACCGTTGTTGCGTGGCTCGCGCTCGCCGTAGTGGCTGGGGCGCAGCAGAACCCTGCGGCGCTGGCGGGGCG
GACGTGGCGCGAGGCGCACG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTTALPPVQDTLAQPIMDLEREYLLQNYARYPLVLARGKGCYLYDLAGKRYLDLISGIGVNALGHAHPRITKVIRAQAAL
LLHTSNLYYHEYQGALAKRLAQMSGLQRCFFSNTGTEAVEGALKMAHSHGRAIHSDKYEVIALDNSFHGRTLGALSITGQ
AKYRQDFEPLVPGARFVPANDIAALEGAFSERTAAIVLEMIQGEGGINPLSPEYVVKARELADRYNALLVLDETQCGVGR
PGTYFSYQRSSHITMPDVMVSAKPLACGIPLGVIMANERAAAAIKPGMHGSTFGGGPLACRVALEFCDILDELLPSIQRV
GGYLHVELNELARKHSFIKEVRGFGLMIGVELAMPGKQLVLDAMAQGLLINCTHDTVLRFLPPYIITEKEVDLAVRTLGK
IFSRVK

Sequences:

>Translated_406_residues
MTTALPPVQDTLAQPIMDLEREYLLQNYARYPLVLARGKGCYLYDLAGKRYLDLISGIGVNALGHAHPRITKVIRAQAAL
LLHTSNLYYHEYQGALAKRLAQMSGLQRCFFSNTGTEAVEGALKMAHSHGRAIHSDKYEVIALDNSFHGRTLGALSITGQ
AKYRQDFEPLVPGARFVPANDIAALEGAFSERTAAIVLEMIQGEGGINPLSPEYVVKARELADRYNALLVLDETQCGVGR
PGTYFSYQRSSHITMPDVMVSAKPLACGIPLGVIMANERAAAAIKPGMHGSTFGGGPLACRVALEFCDILDELLPSIQRV
GGYLHVELNELARKHSFIKEVRGFGLMIGVELAMPGKQLVLDAMAQGLLINCTHDTVLRFLPPYIITEKEVDLAVRTLGK
IFSRVK
>Mature_405_residues
TTALPPVQDTLAQPIMDLEREYLLQNYARYPLVLARGKGCYLYDLAGKRYLDLISGIGVNALGHAHPRITKVIRAQAALL
LHTSNLYYHEYQGALAKRLAQMSGLQRCFFSNTGTEAVEGALKMAHSHGRAIHSDKYEVIALDNSFHGRTLGALSITGQA
KYRQDFEPLVPGARFVPANDIAALEGAFSERTAAIVLEMIQGEGGINPLSPEYVVKARELADRYNALLVLDETQCGVGRP
GTYFSYQRSSHITMPDVMVSAKPLACGIPLGVIMANERAAAAIKPGMHGSTFGGGPLACRVALEFCDILDELLPSIQRVG
GYLHVELNELARKHSFIKEVRGFGLMIGVELAMPGKQLVLDAMAQGLLINCTHDTVLRFLPPYIITEKEVDLAVRTLGKI
FSRVK

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=406, Percent_Identity=32.512315270936, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=27.6018099547511, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=33.4448160535117, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI37574042, Length=421, Percent_Identity=28.7410926365796, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI226442705, Length=421, Percent_Identity=27.790973871734, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=28.7564766839378, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI24119277, Length=380, Percent_Identity=28.6842105263158, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI188536080, Length=426, Percent_Identity=24.4131455399061, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38679950, Length=426, Percent_Identity=24.4131455399061, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38679946, Length=426, Percent_Identity=24.4131455399061, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1788044, Length=389, Percent_Identity=38.3033419023136, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=36.2244897959184, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI145693181, Length=383, Percent_Identity=33.420365535248, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1789016, Length=410, Percent_Identity=30.9756097560976, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=32.9113924050633, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786991, Length=392, Percent_Identity=27.8061224489796, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1786349, Length=282, Percent_Identity=26.5957446808511, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25144271, Length=400, Percent_Identity=32, Blast_Score=228, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=29.6551724137931, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI25144274, Length=292, Percent_Identity=32.1917808219178, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=23.6533957845433, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71981843, Length=173, Percent_Identity=30.635838150289, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17541228, Length=462, Percent_Identity=23.3766233766234, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=402, Percent_Identity=35.0746268656716, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6323470, Length=413, Percent_Identity=33.1719128329298, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6324386, Length=469, Percent_Identity=24.0938166311301, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=445, Percent_Identity=23.3707865168539, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21357415, Length=390, Percent_Identity=32.5641025641026, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI161085790, Length=450, Percent_Identity=29.5555555555556, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI28574759, Length=446, Percent_Identity=30.0448430493274, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI21356575, Length=412, Percent_Identity=26.2135922330097, Blast_Score=138, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 44361; Mature: 44230

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTALPPVQDTLAQPIMDLEREYLLQNYARYPLVLARGKGCYLYDLAGKRYLDLISGIGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHCCCC
NALGHAHPRITKVIRAQAALLLHTSNLYYHEYQGALAKRLAQMSGLQRCFFSNTGTEAVE
CCCCCCCHHHHHHHHHHHHEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GALKMAHSHGRAIHSDKYEVIALDNSFHGRTLGALSITGQAKYRQDFEPLVPGARFVPAN
HHHHHHHHCCCCEECCCEEEEEECCCCCCCEEEEEEECCCHHHHCCCHHCCCCCEECCCC
DIAALEGAFSERTAAIVLEMIQGEGGINPLSPEYVVKARELADRYNALLVLDETQCGVGR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCC
PGTYFSYQRSSHITMPDVMVSAKPLACGIPLGVIMANERAAAAIKPGMHGSTFGGGPLAC
CCCEEEECCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCHHHCCCCCCCCCCCCCHHHH
RVALEFCDILDELLPSIQRVGGYLHVELNELARKHSFIKEVRGFGLMIGVELAMPGKQLV
HHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCEEEEEEEEECCCHHHH
LDAMAQGLLINCTHDTVLRFLPPYIITEKEVDLAVRTLGKIFSRVK
HHHHHCCEEEECCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTALPPVQDTLAQPIMDLEREYLLQNYARYPLVLARGKGCYLYDLAGKRYLDLISGIGV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHCCCC
NALGHAHPRITKVIRAQAALLLHTSNLYYHEYQGALAKRLAQMSGLQRCFFSNTGTEAVE
CCCCCCCHHHHHHHHHHHHEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GALKMAHSHGRAIHSDKYEVIALDNSFHGRTLGALSITGQAKYRQDFEPLVPGARFVPAN
HHHHHHHHCCCCEECCCEEEEEECCCCCCCEEEEEEECCCHHHHCCCHHCCCCCEECCCC
DIAALEGAFSERTAAIVLEMIQGEGGINPLSPEYVVKARELADRYNALLVLDETQCGVGR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCC
PGTYFSYQRSSHITMPDVMVSAKPLACGIPLGVIMANERAAAAIKPGMHGSTFGGGPLAC
CCCEEEECCCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCHHHCCCCCCCCCCCCCHHHH
RVALEFCDILDELLPSIQRVGGYLHVELNELARKHSFIKEVRGFGLMIGVELAMPGKQLV
HHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHCCEEEEEEEEECCCHHHH
LDAMAQGLLINCTHDTVLRFLPPYIITEKEVDLAVRTLGKIFSRVK
HHHHHCCEEEECCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]