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The map label for this gene is iolG [H]

Identifier: 116621809

GI number: 116621809

Start: 3410883

End: 3412211

Strand: Reverse

Name: iolG [H]

Synonym: Acid_2691

Alternate gene names: 116621809

Gene position: 3412211-3410883 (Counterclockwise)

Preceding gene: 116621812

Following gene: 116621806

Centisome position: 34.24

GC content: 64.48

Gene sequence:

>1329_bases
ATGAGCACGCGACGAGATTTTCTGCTAACGGGCGGCGCGATGGCGACAAGCCTGGCGTCACAGGGAACATCACAAACAGC
GGCGAACGACCGGATCCGGATCGCGACGATCGGTTTCGGCGGCATGGGAATGGGCGATACGAAATACGCGCTGACGGTTC
CGGGCGTGGAACTGGCGGCGGTATGCGATGTCTACGACGGACGGCGGACCCGGGCGCGCGAGGTGTATGGGGATCAGGTT
TTCACGACGCGCGATTACCGTGAAGTGCTGGCGCGGCGCGACGTGGACGCGGTGATCATCGCCACGCCGGATCACTGGCA
CTCGACGATTTCTATCGCGGCGATGGAAGCCGGCAAGGACGTCTATTGCGAAAAGCCGATGGTGCAGACGGTGGGCGAAG
GTCAGGCGGTGGTGGCGGCGCAGGAGAAGACGAGACGGATCTTCCAGGTGGGCAGTCAGTACGTGACGTCGCTGGTATAT
CAGAAGGCGCGGGACCTGATCGCGGCGGGCGCGATCGGGAGCATCAATCTGGTGGAAGCGTGGCTGAACCGGAATACGGC
GATGGGGGCGTGGCAATACTCGATTCCGCCGGACGCGTCGCCGGCGACGGTGGATTGGGACCGGTTTTTGGGACGCGCGC
CGAAGCGCCCGTTCGACGCGGTGCGCATGTTCCGGTGGCGCAATTACCAGGATTACGGGACGGGTGTGGCCGGCGATTTG
TTCGTGCATCTGCTGAGCGGGCTGCACGTGGCGACGGGGTCGGTGGGTCCGGAGCGGATTCTGGCGACGGGCGGCCTGCG
GTATTGGAATGACGGGCGCGACGTGCCGGACGTGATGCTGGCGATGCTGGACTATCCCAAACAGAAGGCTCACCCGGAAT
TCACGATGGCGCTGCGGGTGAACCTGAAGAGCGGCGTGCCGGAGGAGCAGTTCGGATTTCGCTTCATGGGCAGCGAAGGC
GTGATCACGACCAGCATGAGTTCCCTGCGGCTGGAGAAGGCCCCGCCGGAACGGGAGCCGGGGTATTCGGTGGGGACGTT
TCCGAAGGCGGTGCAGGAGGAATTCGTGCGGCAGTACCGGGCGAAGTATCCGGAGGCGAAGGCCGCGGCGAAGATCGAGC
CGGAGGTGTTCACGCCGCCGACGGGTTACGATGCGCATCGCGACCACCACCGCGTGTTTTATGAGGCGGTACGGGCGAGG
AAGCGTCCGGTGGAGGACGCGGTGTTCGGGTTCAGGGCGGCGGGTCCGGCGTTGTTGGCCAATGTCAGCTGCTACGAGAA
GAGGGTGTGTAAGTGGGACGCGGCGGCGATGAGGGAAAAAGCCGATTAG

Upstream 100 bases:

>100_bases
AGCGAGCACGAGTCCGGCCGCGACTGCGAGACAACTTACTTTCATGGGAGATTCTCCTCGATTGAGTATAGGCGTTTTGG
ACCCGATAGAATGGGGGGCA

Downstream 100 bases:

>100_bases
TGGGCGAGCCGGACTCCTATTCTATGAAAGGCTGACGACGGCGGCGCTGACGGGGCGTTCGCCGACGGGGATCATGGTGA
AGAGTGGAGCGGATTTGTAG

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSTRRDFLLTGGAMATSLASQGTSQTAANDRIRIATIGFGGMGMGDTKYALTVPGVELAAVCDVYDGRRTRAREVYGDQV
FTTRDYREVLARRDVDAVIIATPDHWHSTISIAAMEAGKDVYCEKPMVQTVGEGQAVVAAQEKTRRIFQVGSQYVTSLVY
QKARDLIAAGAIGSINLVEAWLNRNTAMGAWQYSIPPDASPATVDWDRFLGRAPKRPFDAVRMFRWRNYQDYGTGVAGDL
FVHLLSGLHVATGSVGPERILATGGLRYWNDGRDVPDVMLAMLDYPKQKAHPEFTMALRVNLKSGVPEEQFGFRFMGSEG
VITTSMSSLRLEKAPPEREPGYSVGTFPKAVQEEFVRQYRAKYPEAKAAAKIEPEVFTPPTGYDAHRDHHRVFYEAVRAR
KRPVEDAVFGFRAAGPALLANVSCYEKRVCKWDAAAMREKAD

Sequences:

>Translated_442_residues
MSTRRDFLLTGGAMATSLASQGTSQTAANDRIRIATIGFGGMGMGDTKYALTVPGVELAAVCDVYDGRRTRAREVYGDQV
FTTRDYREVLARRDVDAVIIATPDHWHSTISIAAMEAGKDVYCEKPMVQTVGEGQAVVAAQEKTRRIFQVGSQYVTSLVY
QKARDLIAAGAIGSINLVEAWLNRNTAMGAWQYSIPPDASPATVDWDRFLGRAPKRPFDAVRMFRWRNYQDYGTGVAGDL
FVHLLSGLHVATGSVGPERILATGGLRYWNDGRDVPDVMLAMLDYPKQKAHPEFTMALRVNLKSGVPEEQFGFRFMGSEG
VITTSMSSLRLEKAPPEREPGYSVGTFPKAVQEEFVRQYRAKYPEAKAAAKIEPEVFTPPTGYDAHRDHHRVFYEAVRAR
KRPVEDAVFGFRAAGPALLANVSCYEKRVCKWDAAAMREKAD
>Mature_441_residues
STRRDFLLTGGAMATSLASQGTSQTAANDRIRIATIGFGGMGMGDTKYALTVPGVELAAVCDVYDGRRTRAREVYGDQVF
TTRDYREVLARRDVDAVIIATPDHWHSTISIAAMEAGKDVYCEKPMVQTVGEGQAVVAAQEKTRRIFQVGSQYVTSLVYQ
KARDLIAAGAIGSINLVEAWLNRNTAMGAWQYSIPPDASPATVDWDRFLGRAPKRPFDAVRMFRWRNYQDYGTGVAGDLF
VHLLSGLHVATGSVGPERILATGGLRYWNDGRDVPDVMLAMLDYPKQKAHPEFTMALRVNLKSGVPEEQFGFRFMGSEGV
ITTSMSSLRLEKAPPEREPGYSVGTFPKAVQEEFVRQYRAKYPEAKAAAKIEPEVFTPPTGYDAHRDHHRVFYEAVRARK
RPVEDAVFGFRAAGPALLANVSCYEKRVCKWDAAAMREKAD

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 48941; Mature: 48810

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRRDFLLTGGAMATSLASQGTSQTAANDRIRIATIGFGGMGMGDTKYALTVPGVELAA
CCCCCCEEEECCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCHHHH
VCDVYDGRRTRAREVYGDQVFTTRDYREVLARRDVDAVIIATPDHWHSTISIAAMEAGKD
HHHCCCCCHHHHHHHHCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCC
VYCEKPMVQTVGEGQAVVAAQEKTRRIFQVGSQYVTSLVYQKARDLIAAGAIGSINLVEA
CCCCCCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
WLNRNTAMGAWQYSIPPDASPATVDWDRFLGRAPKRPFDAVRMFRWRNYQDYGTGVAGDL
HHCCCCCCCEEEECCCCCCCCCEECHHHHHCCCCCCHHHHHHHHHHCCCHHHCCCHHHHH
FVHLLSGLHVATGSVGPERILATGGLRYWNDGRDVPDVMLAMLDYPKQKAHPEFTMALRV
HHHHHHCCEEECCCCCHHHHHCCCCCEECCCCCCHHHHHHHHHCCCHHHCCCCEEEEEEE
NLKSGVPEEQFGFRFMGSEGVITTSMSSLRLEKAPPEREPGYSVGTFPKAVQEEFVRQYR
EECCCCCHHHCCEEEECCCCEEEECHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AKYPEAKAAAKIEPEVFTPPTGYDAHRDHHRVFYEAVRARKRPVEDAVFGFRAAGPALLA
HHCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHH
NVSCYEKRVCKWDAAAMREKAD
CCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STRRDFLLTGGAMATSLASQGTSQTAANDRIRIATIGFGGMGMGDTKYALTVPGVELAA
CCCCCEEEECCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCHHHH
VCDVYDGRRTRAREVYGDQVFTTRDYREVLARRDVDAVIIATPDHWHSTISIAAMEAGKD
HHHCCCCCHHHHHHHHCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCC
VYCEKPMVQTVGEGQAVVAAQEKTRRIFQVGSQYVTSLVYQKARDLIAAGAIGSINLVEA
CCCCCCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
WLNRNTAMGAWQYSIPPDASPATVDWDRFLGRAPKRPFDAVRMFRWRNYQDYGTGVAGDL
HHCCCCCCCEEEECCCCCCCCCEECHHHHHCCCCCCHHHHHHHHHHCCCHHHCCCHHHHH
FVHLLSGLHVATGSVGPERILATGGLRYWNDGRDVPDVMLAMLDYPKQKAHPEFTMALRV
HHHHHHCCEEECCCCCHHHHHCCCCCEECCCCCCHHHHHHHHHCCCHHHCCCCEEEEEEE
NLKSGVPEEQFGFRFMGSEGVITTSMSSLRLEKAPPEREPGYSVGTFPKAVQEEFVRQYR
EECCCCCHHHCCEEEECCCCEEEECHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AKYPEAKAAAKIEPEVFTPPTGYDAHRDHHRVFYEAVRARKRPVEDAVFGFRAAGPALLA
HHCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHH
NVSCYEKRVCKWDAAAMREKAD
CCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA