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The map label for this gene is insF1 [C]

Identifier: 116621711

GI number: 116621711

Start: 3274765

End: 3275697

Strand: Direct

Name: insF1 [C]

Synonym: Acid_2593

Alternate gene names: 116621711

Gene position: 3274765-3275697 (Clockwise)

Preceding gene: 116621710

Following gene: 116621712

Centisome position: 32.86

GC content: 59.59

Gene sequence:

>933_bases
ATGACGCAAGAGCAAGGCAAGTTAAGCATCCAACGGATGTGCCAACTCGTCGGCGTCAGCCGGGCCGGATATTACCGGCA
CTGGGAGGTCGTAGCTCCGGACGAAGCGGAAATGGCGGCCAGGGATGCCATCCAGAAGGTGGTGCTCGCGCACCATCGAC
GGTACGGCTACCGGCGCGTCACCGCGCAACTGCATCGACAGGGAAACATCATCAATCACAAGCGGGTGCTGCGCATTATG
GGTGAGGACAACCTGCTGGCGATCCGCTACCGCAAGTACATTATGACCACCGATTCGCGGCACGACTACCCGGTCTACGT
GAATCTGGCTGCGCGCATGACATTGACCGGCATCAACCAGCTGTGGATCGCCGACATCACCTACATCCGGCTGCGCAGGG
AGTTTGTCTATCTGGCGATCGTGCTCGACCGATTCTCACGTAAGGCAATCGGTTGGTCGCTGGATCGGGCGCTGGCTGCC
CGAATCGCGGTGGCGGCCTTGGAGCAGGCCGTGGAGAGACGGCAGCCGCCGCCGGGCGTGGTGGTGCACAACGATCAGGG
TATCCAGTTTGTCTGCCACGAATTTCAAGAGGTGGTGAAAGCTCACGGGATGGTGCCCAGCCTGAGCCGCCCGGCGAATC
CGTACGACAATGCCGCCTGTGAAAGTTTCATGAAGACGCTGAAGCAGGAGGAAATCTACTGCCACCGGTACCAGGATTTC
GATGAACTTTCCGCCCATGTGGAAGAGTTCATCGAAACCTACTACAACCGGCAACGGCTGCACTCGGCACTGGGCTATCG
GACGCCGGAAGAATTTGAGCGGGATGGCATCTCAGCCCCGAATTCCGGCACCCACAATGCGGCGACCATGCTGGTGTTTA
CTCCGAAGGAAGAAGAGGGTTCCGGCGGGCCAGATTCCATCTCTCCGCGATGA

Upstream 100 bases:

>100_bases
ATAAAGTCCTGGAGATCGAGCTTTTTCAACATGCCTTGCTCAAATTAAAGGAGGCACGGCCACAGCCTGGCGCCTCAGCG
TCTACGAAGTCATCCGTTCG

Downstream 100 bases:

>100_bases
CTCAGGCAAAGAAATGGCACGAAAGGCAAAGTTCGCCCGCTACCGGGAACATCTCCGCACGACCGGGCCGGTCAGCCCTG
GGGGGTCTTCCATCGTCAAG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRIM
GEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQLWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAA
RIAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDF
DELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAATMLVFTPKEEEGSGGPDSISPR

Sequences:

>Translated_310_residues
MTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRIM
GEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQLWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAA
RIAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDF
DELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAATMLVFTPKEEEGSGGPDSISPR
>Mature_309_residues
TQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRIMG
EDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQLWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAAR
IAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDFD
ELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAATMLVFTPKEEEGSGGPDSISPR

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=239, Percent_Identity=28.4518828451883, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788405, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1787263, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1786753, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1786570, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1786490, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1789981, Length=258, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1790724, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1789424, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1789224, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788305, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787669, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786558, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 35675; Mature: 35544

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRV
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHH
TAQLHRQGNIINHKRVLRIMGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQ
HHHHHHCCCCCCHHHHHHEECCCCEEEEEEEEEEEECCCCCCCCEEEEEEHHEEHHCCCH
LWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDF
EEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
DELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAATMLVFTPKEEEG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCC
SGGPDSISPR
CCCCCCCCCC
>Mature Secondary Structure 
TQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRV
CCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHH
TAQLHRQGNIINHKRVLRIMGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQ
HHHHHHCCCCCCHHHHHHEECCCCEEEEEEEEEEEECCCCCCCCEEEEEEHHEEHHCCCH
LWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDF
EEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
DELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAATMLVFTPKEEEG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCC
SGGPDSISPR
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]