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The map label for this gene is sigM [H]

Identifier: 116621630

GI number: 116621630

Start: 3186297

End: 3186758

Strand: Reverse

Name: sigM [H]

Synonym: Acid_2512

Alternate gene names: 116621630

Gene position: 3186758-3186297 (Counterclockwise)

Preceding gene: 116621634

Following gene: 116621629

Centisome position: 31.98

GC content: 61.26

Gene sequence:

>462_bases
TTGGAGCAGTTGTTGACCAGATATGAAACGCCCGTATACCGCATGGCCCTCACGTTCCTGAAAGACCCCGGCCGCGCCGA
AGACATCACGCAGGACATCTTCCTCAAGCTTTGGCGGGCCTTGCCGGACTACGATGGGCGCGCCTCACCGGGCACATGGC
TGTACACGATCGCCCGAAATACCTGCCTCTCCGCCGCGCGGTCGGCTTCGTACCGTAAGACAATCCCGCTGGAGTCAACC
AGCGAACCGGCGGCTCCTGCAGCGGCGCCGTCGGGAGACGTTGAATTGGCGCAGTGCATTGACCGGTTGCCGGAAACCCA
GCGTACCGTGATCACCCTCTTCTACCTTCAGGAAAGGCGCGTAGACGAAGTGGCGCGCATGTTGGGAATCCCCGAGGGAA
CCGTGAAAAGCCATTTGTACCGGGCCCGCCTCGCGCTGGGCGAAATGATGAAGGAGTCATGA

Upstream 100 bases:

>100_bases
GCATTTACCGTGCAACCCCGACCATCGCTCGCGAGTACCAATAGGCTGAATGGATGAAGACGTTCAACTTCTGCTTCGAA
AACGGAGGTACCCGGAAGCC

Downstream 100 bases:

>100_bases
TGAATTGCGAAGAAGCTCGTCAGGTCCTGATGGACTCCCTCGACGTATCGATTGCCGCCGCACGCGATCCCATGGCCGAA
TCCCACGCCGCATCATGCGA

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MEQLLTRYETPVYRMALTFLKDPGRAEDITQDIFLKLWRALPDYDGRASPGTWLYTIARNTCLSAARSASYRKTIPLEST
SEPAAPAAAPSGDVELAQCIDRLPETQRTVITLFYLQERRVDEVARMLGIPEGTVKSHLYRARLALGEMMKES

Sequences:

>Translated_153_residues
MEQLLTRYETPVYRMALTFLKDPGRAEDITQDIFLKLWRALPDYDGRASPGTWLYTIARNTCLSAARSASYRKTIPLEST
SEPAAPAAAPSGDVELAQCIDRLPETQRTVITLFYLQERRVDEVARMLGIPEGTVKSHLYRARLALGEMMKES
>Mature_153_residues
MEQLLTRYETPVYRMALTFLKDPGRAEDITQDIFLKLWRALPDYDGRASPGTWLYTIARNTCLSAARSASYRKTIPLEST
SEPAAPAAAPSGDVELAQCIDRLPETQRTVITLFYLQERRVDEVARMLGIPEGTVKSHLYRARLALGEMMKES

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt, acid and e

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=163, Percent_Identity=27.6073619631902, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014296
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 17283; Mature: 17283

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLLTRYETPVYRMALTFLKDPGRAEDITQDIFLKLWRALPDYDGRASPGTWLYTIARN
CHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHH
TCLSAARSASYRKTIPLESTSEPAAPAAAPSGDVELAQCIDRLPETQRTVITLFYLQERR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
VDEVARMLGIPEGTVKSHLYRARLALGEMMKES
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQLLTRYETPVYRMALTFLKDPGRAEDITQDIFLKLWRALPDYDGRASPGTWLYTIARN
CHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHH
TCLSAARSASYRKTIPLESTSEPAAPAAAPSGDVELAQCIDRLPETQRTVITLFYLQERR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
VDEVARMLGIPEGTVKSHLYRARLALGEMMKES
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 12775685; 10216858 [H]