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The map label for this gene is macB [H]

Identifier: 116621610

GI number: 116621610

Start: 3160540

End: 3163062

Strand: Direct

Name: macB [H]

Synonym: Acid_2492

Alternate gene names: 116621610

Gene position: 3160540-3163062 (Clockwise)

Preceding gene: 116621609

Following gene: 116621612

Centisome position: 31.71

GC content: 67.1

Gene sequence:

>2523_bases
ATGTCCTGGCTTTCGAGACTGAAGAACGCGGTGTTTCCCGGCCGGCTGGACGAGGAACTGGCGGAAGAGATGCGCGACCA
CCTGGAACGCCGCGCGGAGGAGTTGGAAGCACGAGGGCTCGACCGGCGCGAGGCGCGGCGGCAGGCGGCACTGCGCTTTG
GCAACGTGACGGGCGTGCGCGAGAGCAGCCGGGAACTGCGGCTGTGGGCGGAGCTCGAAGGGAGCCTGCAGGACGTGCGG
TACGCATGGCGCGGGCTGCTGCGGAATCCGATCTTCGCGGCGACGGCGGTGGCTTCGCTGGGGCTGGCGATCGGCGCGAA
TACCGCGATCTATTCGATTGTGGATGCGGCGGTGCTGCGGCCGCTGCCGGTAACGGACCCCGACCGTTTGATCACGCTGG
CAAAGGGCGACGACGACCTGTTCAGCTTCCCACGCTACGAGGAACTGCGCGCCGCGGCAGGAGACGGGGCGCGGCTCGCG
CTGGTGGGCGGAGCGGACCGCGTGGAAGCGAAGGCATGGTACGACGATGCTCCGTATGAAGAAGTGACGGAGCAATACTG
CTCCGCGAACACGTTCGAAGTGATGGGCGTCGGGCCCGCGGCGGGTTCACTCGAGACGCGTGACGGGGTGGTGCTCAGTT
ACGAGTATTGGCGACGACGCTTCGGCGGGGACGGCGCGATTGTGGGGAAATGGCTGGCGATCGACGGCAGGATGTATGCC
ATTGCCGGGGTGGCGCGGGAGGGATTTTCGGGCGCGGAGCCGGGGAGGTTCGTGGACGTGTGGATACCGGTCACGATGAT
GGATCCGGCGATTTTCACGAATGCGGACGTCCGGCTGTTCCACGTGATGGGGCGGCTGGCTCCGGGGGTGGAACGGGAGC
GGCTGGCGAGCATGCTGCGGGCCGGACTGACGGTGAACTCCGGGGCGCACGGCGTCTCGGCCTTCCGAAAGACATTTGCG
CGGCCGTTGTGGATTCTGCTCGGAGTTGCGGGCTGCACTCTGCTGATTGCGTGCGCGAATGTGGCGAGTCTGCTGCTGGC
ACGATCCACGGCGCGGTCGGCGGAGATGGCTCTGCGGGTTTCGCTGGGAGCGCGGCGGGCGCGGCTGGTGCGCCAACTGC
TGACGGAGAGCCTTATGATTTCCGTGCTGGCGGGATTATGCGGATGGGCAATTGCGGGCGCGGCGGCTCCGGCGTTGGTG
ACGATGGTTTCGACCGCGGCAAGTCCGGTGCGGCTGGAGCTGGCAGTGGACACGCGCATGTTGTGGTTCTGCGCGGGGGT
GTGCGGGTTGTGCGCGCTGTTCTTTGGCCTGCTGCCGGCGTGGCAGGCAACGAGATCGCGGCCGATGTTCGCATTGCGCC
ATGGGGCGGGGCAATCGGCACGGCTGCGGATGGGGAGATTATTCGTGGGAATCCAGGTGGCTTTCGCGTTCTGCCTGGTA
ACGGGAGGGAGCGGATTTCTTTTGAGCCTGCACAACCTGACGGCGGTGGACACGGGATTCGACGCGAAGGGTGTCACGGT
GCTGACGGTGAGCAACACGCAGCAGCGGGACCGGCAACTGGCGATGCTGCAGGAGGTGCAGCGGCGAACCGCGGCGCTGC
CCGAGGTGCGCGGGGCGGCGACGAGCTGGATGCCGCTTCTTTCGGGGGCGCGGCGCGCGCAGAGGGTCGTGCTGCCAGGG
CAGCGGCCGTCGGAGCGCGAAGAGACGTTTTACCGCGTGTCGCCGGGCTACCTGGCGACGCTCGGCACGCCCCTGATGAG
CGGGCGTGATTTCAGGCCGGCCGACAATGACGACGAGCCGGTGCCGACGATTGTGAATCGTGCATTCGCGCGGCGGTATT
ACGGGAGCGAGGCAGTGCTGGGCCGGGAGTTCCGGCGCGACGACGGAGTGCGGCACCAGATCGTCGGGGTGGCGGGGAAC
TCGCATTTCGGGAGCCTGCGCGATGCAGCGGAGGGGATCGCGTATATGCCGATGAAGCCGCCGCGTGCGTTCACGTTGTA
TGTGCGCTCGCGGCTGGATGCGGGGTCGGTGGCGAAGATGGTGGAGCGCGAGTTGGAGACGCTGGGAGCGGGAGTAAGAG
TCCGGGACGTGACCACGCTGGAGGCGATCGTGGGCCGGACGATTGTGAAGGAGCGGCTGCTGGCGAGAATCGGCGGGAGT
TTTGCGCTGCTGGGGCTGGTGCTGGCGGCGATCGGATTGTTCGGACTGCTGAATTATTCGGTGACGCTAAAAACGAAGGA
GATCGGCATCCGGGCGGCGTTGGGGGCGCAGAGGATGGCGATTTGCGGGCTGGTGTTGAAGGACACGGCGCTGCTGATCG
CTGGAGGATTGGTGGTTGGACTGGCGGGGTCGCTGGCGCTGATGAGGGCCACGGAGTCGCTTTTGTTTGGAGTGGCGGCG
GCGGACGGGAGAGTGATCGGCGGAGCGGCGGTGATTTTTGCGGGGGCGGCAATGATTGCGGCGGGGTTGCCTGCAAGGCG
GGCGGCGGCGATCGATCCGGTGGTGGCGCTGCGGCAGGAGTGA

Upstream 100 bases:

>100_bases
GGCGGGGCTGAAGCAACTCGCGGCCGAGACGGAGAGCTGGAAGAGTTTTTCGGCGGGTGTGGCGCGCGTGTTGCGGCACG
CCTAGGCGGGAGGGGGAAGG

Downstream 100 bases:

>100_bases
GGGAAAGAGATCTGCCGGACGGTCGCGGTTCGGACGACCGCGGTTCGCATGTGCCATGCTGGCTTTATGCGAGACCCGGA
GACCATCGATACGGAGTTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 840; Mature: 839

Protein sequence:

>840_residues
MSWLSRLKNAVFPGRLDEELAEEMRDHLERRAEELEARGLDRREARRQAALRFGNVTGVRESSRELRLWAELEGSLQDVR
YAWRGLLRNPIFAATAVASLGLAIGANTAIYSIVDAAVLRPLPVTDPDRLITLAKGDDDLFSFPRYEELRAAAGDGARLA
LVGGADRVEAKAWYDDAPYEEVTEQYCSANTFEVMGVGPAAGSLETRDGVVLSYEYWRRRFGGDGAIVGKWLAIDGRMYA
IAGVAREGFSGAEPGRFVDVWIPVTMMDPAIFTNADVRLFHVMGRLAPGVERERLASMLRAGLTVNSGAHGVSAFRKTFA
RPLWILLGVAGCTLLIACANVASLLLARSTARSAEMALRVSLGARRARLVRQLLTESLMISVLAGLCGWAIAGAAAPALV
TMVSTAASPVRLELAVDTRMLWFCAGVCGLCALFFGLLPAWQATRSRPMFALRHGAGQSARLRMGRLFVGIQVAFAFCLV
TGGSGFLLSLHNLTAVDTGFDAKGVTVLTVSNTQQRDRQLAMLQEVQRRTAALPEVRGAATSWMPLLSGARRAQRVVLPG
QRPSEREETFYRVSPGYLATLGTPLMSGRDFRPADNDDEPVPTIVNRAFARRYYGSEAVLGREFRRDDGVRHQIVGVAGN
SHFGSLRDAAEGIAYMPMKPPRAFTLYVRSRLDAGSVAKMVERELETLGAGVRVRDVTTLEAIVGRTIVKERLLARIGGS
FALLGLVLAAIGLFGLLNYSVTLKTKEIGIRAALGAQRMAICGLVLKDTALLIAGGLVVGLAGSLALMRATESLLFGVAA
ADGRVIGGAAVIFAGAAMIAAGLPARRAAAIDPVVALRQE

Sequences:

>Translated_840_residues
MSWLSRLKNAVFPGRLDEELAEEMRDHLERRAEELEARGLDRREARRQAALRFGNVTGVRESSRELRLWAELEGSLQDVR
YAWRGLLRNPIFAATAVASLGLAIGANTAIYSIVDAAVLRPLPVTDPDRLITLAKGDDDLFSFPRYEELRAAAGDGARLA
LVGGADRVEAKAWYDDAPYEEVTEQYCSANTFEVMGVGPAAGSLETRDGVVLSYEYWRRRFGGDGAIVGKWLAIDGRMYA
IAGVAREGFSGAEPGRFVDVWIPVTMMDPAIFTNADVRLFHVMGRLAPGVERERLASMLRAGLTVNSGAHGVSAFRKTFA
RPLWILLGVAGCTLLIACANVASLLLARSTARSAEMALRVSLGARRARLVRQLLTESLMISVLAGLCGWAIAGAAAPALV
TMVSTAASPVRLELAVDTRMLWFCAGVCGLCALFFGLLPAWQATRSRPMFALRHGAGQSARLRMGRLFVGIQVAFAFCLV
TGGSGFLLSLHNLTAVDTGFDAKGVTVLTVSNTQQRDRQLAMLQEVQRRTAALPEVRGAATSWMPLLSGARRAQRVVLPG
QRPSEREETFYRVSPGYLATLGTPLMSGRDFRPADNDDEPVPTIVNRAFARRYYGSEAVLGREFRRDDGVRHQIVGVAGN
SHFGSLRDAAEGIAYMPMKPPRAFTLYVRSRLDAGSVAKMVERELETLGAGVRVRDVTTLEAIVGRTIVKERLLARIGGS
FALLGLVLAAIGLFGLLNYSVTLKTKEIGIRAALGAQRMAICGLVLKDTALLIAGGLVVGLAGSLALMRATESLLFGVAA
ADGRVIGGAAVIFAGAAMIAAGLPARRAAAIDPVVALRQE
>Mature_839_residues
SWLSRLKNAVFPGRLDEELAEEMRDHLERRAEELEARGLDRREARRQAALRFGNVTGVRESSRELRLWAELEGSLQDVRY
AWRGLLRNPIFAATAVASLGLAIGANTAIYSIVDAAVLRPLPVTDPDRLITLAKGDDDLFSFPRYEELRAAAGDGARLAL
VGGADRVEAKAWYDDAPYEEVTEQYCSANTFEVMGVGPAAGSLETRDGVVLSYEYWRRRFGGDGAIVGKWLAIDGRMYAI
AGVAREGFSGAEPGRFVDVWIPVTMMDPAIFTNADVRLFHVMGRLAPGVERERLASMLRAGLTVNSGAHGVSAFRKTFAR
PLWILLGVAGCTLLIACANVASLLLARSTARSAEMALRVSLGARRARLVRQLLTESLMISVLAGLCGWAIAGAAAPALVT
MVSTAASPVRLELAVDTRMLWFCAGVCGLCALFFGLLPAWQATRSRPMFALRHGAGQSARLRMGRLFVGIQVAFAFCLVT
GGSGFLLSLHNLTAVDTGFDAKGVTVLTVSNTQQRDRQLAMLQEVQRRTAALPEVRGAATSWMPLLSGARRAQRVVLPGQ
RPSEREETFYRVSPGYLATLGTPLMSGRDFRPADNDDEPVPTIVNRAFARRYYGSEAVLGREFRRDDGVRHQIVGVAGNS
HFGSLRDAAEGIAYMPMKPPRAFTLYVRSRLDAGSVAKMVERELETLGAGVRVRDVTTLEAIVGRTIVKERLLARIGGSF
ALLGLVLAAIGLFGLLNYSVTLKTKEIGIRAALGAQRMAICGLVLKDTALLIAGGLVVGLAGSLALMRATESLLFGVAAA
DGRVIGGAAVIFAGAAMIAAGLPARRAAAIDPVVALRQE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 90368; Mature: 90237

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLSRLKNAVFPGRLDEELAEEMRDHLERRAEELEARGLDRREARRQAALRFGNVTGVR
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
ESSRELRLWAELEGSLQDVRYAWRGLLRNPIFAATAVASLGLAIGANTAIYSIVDAAVLR
CCCHHEEEHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PLPVTDPDRLITLAKGDDDLFSFPRYEELRAAAGDGARLALVGGADRVEAKAWYDDAPYE
CCCCCCCCCEEEEECCCCHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCHHCCCCCCCHH
EVTEQYCSANTFEVMGVGPAAGSLETRDGVVLSYEYWRRRFGGDGAIVGKWLAIDGRMYA
HHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHCCCCCEEEEEEEECCEEEE
IAGVAREGFSGAEPGRFVDVWIPVTMMDPAIFTNADVRLFHVMGRLAPGVERERLASMLR
EEHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AGLTVNSGAHGVSAFRKTFARPLWILLGVAGCTLLIACANVASLLLARSTARSAEMALRV
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGARRARLVRQLLTESLMISVLAGLCGWAIAGAAAPALVTMVSTAASPVRLELAVDTRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHH
LWFCAGVCGLCALFFGLLPAWQATRSRPMFALRHGAGQSARLRMGRLFVGIQVAFAFCLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
TGGSGFLLSLHNLTAVDTGFDAKGVTVLTVSNTQQRDRQLAMLQEVQRRTAALPEVRGAA
CCCCCEEEEECCCEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHCCH
TSWMPLLSGARRAQRVVLPGQRPSEREETFYRVSPGYLATLGTPLMSGRDFRPADNDDEP
HHHHHHHHHHHHHCEEECCCCCCCCHHCCEEEECCCHHHHHCCHHHCCCCCCCCCCCCCC
VPTIVNRAFARRYYGSEAVLGREFRRDDGVRHQIVGVAGNSHFGSLRDAAEGIAYMPMKP
CHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHCCCEECCCCC
PRAFTLYVRSRLDAGSVAKMVERELETLGAGVRVRDVTTLEAIVGRTIVKERLLARIGGS
CCEEEEEEHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCH
FALLGLVLAAIGLFGLLNYSVTLKTKEIGIRAALGAQRMAICGLVLKDTALLIAGGLVVG
HHHHHHHHHHHHHHHHHCCEEEEEEHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGSLALMRATESLLFGVAAADGRVIGGAAVIFAGAAMIAAGLPARRAAAIDPVVALRQE
HHHHHHHHHHHHHHHHEEECCCCEEECHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
SWLSRLKNAVFPGRLDEELAEEMRDHLERRAEELEARGLDRREARRQAALRFGNVTGVR
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
ESSRELRLWAELEGSLQDVRYAWRGLLRNPIFAATAVASLGLAIGANTAIYSIVDAAVLR
CCCHHEEEHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PLPVTDPDRLITLAKGDDDLFSFPRYEELRAAAGDGARLALVGGADRVEAKAWYDDAPYE
CCCCCCCCCEEEEECCCCHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCHHCCCCCCCHH
EVTEQYCSANTFEVMGVGPAAGSLETRDGVVLSYEYWRRRFGGDGAIVGKWLAIDGRMYA
HHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHCCCCCEEEEEEEECCEEEE
IAGVAREGFSGAEPGRFVDVWIPVTMMDPAIFTNADVRLFHVMGRLAPGVERERLASMLR
EEHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AGLTVNSGAHGVSAFRKTFARPLWILLGVAGCTLLIACANVASLLLARSTARSAEMALRV
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGARRARLVRQLLTESLMISVLAGLCGWAIAGAAAPALVTMVSTAASPVRLELAVDTRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHH
LWFCAGVCGLCALFFGLLPAWQATRSRPMFALRHGAGQSARLRMGRLFVGIQVAFAFCLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
TGGSGFLLSLHNLTAVDTGFDAKGVTVLTVSNTQQRDRQLAMLQEVQRRTAALPEVRGAA
CCCCCEEEEECCCEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHCCH
TSWMPLLSGARRAQRVVLPGQRPSEREETFYRVSPGYLATLGTPLMSGRDFRPADNDDEP
HHHHHHHHHHHHHCEEECCCCCCCCHHCCEEEECCCHHHHHCCHHHCCCCCCCCCCCCCC
VPTIVNRAFARRYYGSEAVLGREFRRDDGVRHQIVGVAGNSHFGSLRDAAEGIAYMPMKP
CHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHCCCEECCCCC
PRAFTLYVRSRLDAGSVAKMVERELETLGAGVRVRDVTTLEAIVGRTIVKERLLARIGGS
CCEEEEEEHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCH
FALLGLVLAAIGLFGLLNYSVTLKTKEIGIRAALGAQRMAICGLVLKDTALLIAGGLVVG
HHHHHHHHHHHHHHHHHCCEEEEEEHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGSLALMRATESLLFGVAAADGRVIGGAAVIFAGAAMIAAGLPARRAAAIDPVVALRQE
HHHHHHHHHHHHHHHHEEECCCCEEECHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA