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The map label for this gene is dapA [H]

Identifier: 116621564

GI number: 116621564

Start: 3107211

End: 3108173

Strand: Reverse

Name: dapA [H]

Synonym: Acid_2446

Alternate gene names: 116621564

Gene position: 3108173-3107211 (Counterclockwise)

Preceding gene: 116621565

Following gene: 116621562

Centisome position: 31.19

GC content: 64.07

Gene sequence:

>963_bases
ATGGAGACTACGCGACGAGGATTTCTTGGCGCCGTGAGCGCGGCGACCACGGTAGCGGCCATGCCGCGCGCTGCGAAGAC
GTCGGCGGTGAAATCGGGCCCGCAATTCTATGTGGCCGCGATCACCCCCTGCGACAGCAAGTTGAAGTTCGACGAAGGGC
TGTATCGCGACCTCATGCCGTTCTTGCGGGAGCGCGGGGCGGATGGAGTGGTCGTGCTGGGGACTACCGGCGAGTTTCCC
TCGTTCTCCGTGGCGGAGCGCAAGCGCGTGGCGGAAACGGCGCTGAAGCATCGCACGGGCCTGCGCATGATCGTGCAGGT
GGGGACGCCGAATCTTCCGGAGACGCTGGAGCTATTGGCGCACGCGACGGCGAACGGTGCGGACGGAGTGCTGTGCATTC
CGCCGTTCTACTTCAAGATGCCGAGCCTGGAAGGGCTGACGAAATACTACTCGCAGGTGCTGGAGGCGTCGAAGGTGCCG
GTGTACCTGTATCACATACCGGGAACGAGCGCGGTGCCGATTTCGCTGGAATTATTGCACAAGCTGGAGCATTATCCGAA
CCTGGCGGGCATCAAGGATTCGACCGGCAGCGCCGAGGGCTACGCGGCGTTCGTCAAGGAGTTCCCCAAGCTCGACATGA
TGAGCGGCACGGATAACAACATTCCGACGGCGCTGGCGCACGGGATGGGGGCGATCCTGATGGGCGGGAATTTGTTCACC
AAGCAATCGGCGGCGGTGTTCGCGGCGCACCGGCAGGGGAAGGACATCACGGAGGCGATGGCGAAGCTGCGCGAAGCCAG
CGCGCTGCTGCGGAGTCCAGGAGCGGGCGGAGTTCCGGCGATTAAGTACGCGCTCGGCGGGCTGGGGCTGCGCGAAAGCT
ATGTGCGTCCGCCGTACACGGATTTGACGGCGGAGCAGAAAGCGGCGCTCAAGCCGAAGGTCGCGGAACTGGCGAAGTTG
TAG

Upstream 100 bases:

>100_bases
ATGTGTATGGTGCCGAAGTGGGGCCTAAGGATGTGAAGAAGTATGTAAGGAAGTAAAGGTGTAATATAGCTGCAAATAGA
TTACACGAAGGAGGGTTCCC

Downstream 100 bases:

>100_bases
TTATTGGCCGCGCCGGCTGGCCACGGGCGTGGCGACGAGGCGACCGGGCATGTCGGCGAGGGCATAGCCCATCACGGCAA
GGGCGGCGACGTTCTTGCGG

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
METTRRGFLGAVSAATTVAAMPRAAKTSAVKSGPQFYVAAITPCDSKLKFDEGLYRDLMPFLRERGADGVVVLGTTGEFP
SFSVAERKRVAETALKHRTGLRMIVQVGTPNLPETLELLAHATANGADGVLCIPPFYFKMPSLEGLTKYYSQVLEASKVP
VYLYHIPGTSAVPISLELLHKLEHYPNLAGIKDSTGSAEGYAAFVKEFPKLDMMSGTDNNIPTALAHGMGAILMGGNLFT
KQSAAVFAAHRQGKDITEAMAKLREASALLRSPGAGGVPAIKYALGGLGLRESYVRPPYTDLTAEQKAALKPKVAELAKL

Sequences:

>Translated_320_residues
METTRRGFLGAVSAATTVAAMPRAAKTSAVKSGPQFYVAAITPCDSKLKFDEGLYRDLMPFLRERGADGVVVLGTTGEFP
SFSVAERKRVAETALKHRTGLRMIVQVGTPNLPETLELLAHATANGADGVLCIPPFYFKMPSLEGLTKYYSQVLEASKVP
VYLYHIPGTSAVPISLELLHKLEHYPNLAGIKDSTGSAEGYAAFVKEFPKLDMMSGTDNNIPTALAHGMGAILMGGNLFT
KQSAAVFAAHRQGKDITEAMAKLREASALLRSPGAGGVPAIKYALGGLGLRESYVRPPYTDLTAEQKAALKPKVAELAKL
>Mature_320_residues
METTRRGFLGAVSAATTVAAMPRAAKTSAVKSGPQFYVAAITPCDSKLKFDEGLYRDLMPFLRERGADGVVVLGTTGEFP
SFSVAERKRVAETALKHRTGLRMIVQVGTPNLPETLELLAHATANGADGVLCIPPFYFKMPSLEGLTKYYSQVLEASKVP
VYLYHIPGTSAVPISLELLHKLEHYPNLAGIKDSTGSAEGYAAFVKEFPKLDMMSGTDNNIPTALAHGMGAILMGGNLFT
KQSAAVFAAHRQGKDITEAMAKLREASALLRSPGAGGVPAIKYALGGLGLRESYVRPPYTDLTAEQKAALKPKVAELAKL

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI13540533, Length=233, Percent_Identity=32.618025751073, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI31543060, Length=274, Percent_Identity=24.8175182481752, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI87082415, Length=270, Percent_Identity=31.4814814814815, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786463, Length=210, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789620, Length=234, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788823, Length=184, Percent_Identity=27.7173913043478, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002220
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 34142; Mature: 34142

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTRRGFLGAVSAATTVAAMPRAAKTSAVKSGPQFYVAAITPCDSKLKFDEGLYRDLMP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
FLRERGADGVVVLGTTGEFPSFSVAERKRVAETALKHRTGLRMIVQVGTPNLPETLELLA
HHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
HATANGADGVLCIPPFYFKMPSLEGLTKYYSQVLEASKVPVYLYHIPGTSAVPISLELLH
HHCCCCCCCEEECCCHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
KLEHYPNLAGIKDSTGSAEGYAAFVKEFPKLDMMSGTDNNIPTALAHGMGAILMGGNLFT
HHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEECCCEEC
KQSAAVFAAHRQGKDITEAMAKLREASALLRSPGAGGVPAIKYALGGLGLRESYVRPPYT
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHCCCCCCC
DLTAEQKAALKPKVAELAKL
CCCCHHHHHCCCHHHHHHCC
>Mature Secondary Structure
METTRRGFLGAVSAATTVAAMPRAAKTSAVKSGPQFYVAAITPCDSKLKFDEGLYRDLMP
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
FLRERGADGVVVLGTTGEFPSFSVAERKRVAETALKHRTGLRMIVQVGTPNLPETLELLA
HHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
HATANGADGVLCIPPFYFKMPSLEGLTKYYSQVLEASKVPVYLYHIPGTSAVPISLELLH
HHCCCCCCCEEECCCHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
KLEHYPNLAGIKDSTGSAEGYAAFVKEFPKLDMMSGTDNNIPTALAHGMGAILMGGNLFT
HHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEECCCEEC
KQSAAVFAAHRQGKDITEAMAKLREASALLRSPGAGGVPAIKYALGGLGLRESYVRPPYT
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHCCCCCCC
DLTAEQKAALKPKVAELAKL
CCCCHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA