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The map label for this gene is proY [C]

Identifier: 116621414

GI number: 116621414

Start: 2935017

End: 2936393

Strand: Direct

Name: proY [C]

Synonym: Acid_2296

Alternate gene names: 116621414

Gene position: 2935017-2936393 (Clockwise)

Preceding gene: 116621412

Following gene: 116621415

Centisome position: 29.45

GC content: 65.58

Gene sequence:

>1377_bases
ATGAGAGAAGAGCTCCGCAAAGAACTCGGACTCAGCGATCTCGTGTTGGCCCAAGTCCTGTGTGTGGTCGGCTCCTCCTG
GGTCGGCATCGCCGCCAAGCTCGGCCGCGCGCATGTCGTCTTTTGGGTCGTCTCGATGCTGCTCTTCTACCTTCCGCTCG
CAGCCGTCGTGATCTATCTGAATCGTCTGATCCCGCTCGAAGGCGGACTCTACCAGTGGGCCAAGCAGGGCTTCGGCGAA
ATGGCCGGCTTCCTCATCGCCTGGAATTTGTGGGTCTACGCAGTGGTCGTGATGGGCGCGATCATCTTCGTGGTGCCGAC
CGATCTAGCCTTCATGCTCGGCGGCTCGTGGACCTGGCTCCCGCACAGCCGCTGGGCCACGCTCGCCCTGACCGGCGGCG
TGATGGCCGCGATCACCGTCGTCGCCGTGCTCGGTCTCAACATCGGCAAGTGGCTGCACAACGCGGGCAGCGTCATGATT
CTCACGGCTTACGTGATCCTGCTCGGCCTCCCGGTCTGGGCGATGGCGCACGGCTCCGCCACGCACTTCGAGGCGCTGCC
CTTCGAGTGGCCCAAGGCGAGCTGGTTCAGCCTCGCCATCTTCGGGCAGATGACGGTGGGCGCGCTCAGCGGCTTCGAAT
ACGTCGCCATCATGGCGGGGGAATGCCGCAGTGCCGCGCGCACCATCGGCCAATCCGTCCTCATCTCCGCGCCGATCATC
GCCGTGATGTTCATCCTAGGCACCAGCGTCGTGCTCGCCTTCATCGGGAACCAGCCCATTAACGTGATCGGGCCCATCCC
CCAGACCTTCCGTCTCGCCTTCGGCAACACCGGCATCGCGGGCTTCGCCGCGCAGTTCGGCATCGCCATGCTGCTGGCGC
GCGCGGTGGCCAGTTCGAGCCTGATCTTCACCGGACTCTCGCGCCTGCCCATGACGGCCGGCTGGGACAACCTGGCGCCG
AAATGGTTCACCCGCCTCCACCCGCGCCGCCGCACTCCCGTGAACTCCATCCTCTTCGTCGCGGCGCTCGCGATGGGCCT
CATCCTCCTTAGCCTGATGGGTGCGCGGGAACAGGAGGCCAGCCAGCTGCTGACCGCCGCGTCCATCGTTCACTACGCGA
TCGTCTACGTGGCGCTGTTCGCCCTGCCTCTATTCGGCAGCGCGGCTTTGCGCAAACAATTGCCGGGCTGGCTCAAATTG
ACCGCGGCCGCCGGCCTGATCTCAAGCCTCGTGGCGCTCTGCATCTCCGCCTACCCGGTGGTCGATGTCACCAGCCGCGC
CGCGTTCGCCGGCAAGATCTGCGCGGTGGTCGCGATCAGCAACATGGGCGGCGTACTGCTGTATCGCGCCGGCCGCGCCA
GGAATACACTGGAATGA

Upstream 100 bases:

>100_bases
CCCCGCCAACCGCGCGCGCCAGTTTGCGGCCAATCCTGGCTGGTGCAGGCCCGGTGTAGGGAGGTTTCCTTGCCGGGATC
TGTGGCATGATGATTTGACC

Downstream 100 bases:

>100_bases
TCGAGACATGCTGCGCCGCCACGCCATCGCGAGTCTTTTCGCCGCTGGAGCCTGGGGGAAAGTCGCGCTCGATAGCTTGT
TCGAAGGCGCGCACGGCGGC

Product: amino acid permease-associated protein

Products: Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MREELRKELGLSDLVLAQVLCVVGSSWVGIAAKLGRAHVVFWVVSMLLFYLPLAAVVIYLNRLIPLEGGLYQWAKQGFGE
MAGFLIAWNLWVYAVVVMGAIIFVVPTDLAFMLGGSWTWLPHSRWATLALTGGVMAAITVVAVLGLNIGKWLHNAGSVMI
LTAYVILLGLPVWAMAHGSATHFEALPFEWPKASWFSLAIFGQMTVGALSGFEYVAIMAGECRSAARTIGQSVLISAPII
AVMFILGTSVVLAFIGNQPINVIGPIPQTFRLAFGNTGIAGFAAQFGIAMLLARAVASSSLIFTGLSRLPMTAGWDNLAP
KWFTRLHPRRRTPVNSILFVAALAMGLILLSLMGAREQEASQLLTAASIVHYAIVYVALFALPLFGSAALRKQLPGWLKL
TAAAGLISSLVALCISAYPVVDVTSRAAFAGKICAVVAISNMGGVLLYRAGRARNTLE

Sequences:

>Translated_458_residues
MREELRKELGLSDLVLAQVLCVVGSSWVGIAAKLGRAHVVFWVVSMLLFYLPLAAVVIYLNRLIPLEGGLYQWAKQGFGE
MAGFLIAWNLWVYAVVVMGAIIFVVPTDLAFMLGGSWTWLPHSRWATLALTGGVMAAITVVAVLGLNIGKWLHNAGSVMI
LTAYVILLGLPVWAMAHGSATHFEALPFEWPKASWFSLAIFGQMTVGALSGFEYVAIMAGECRSAARTIGQSVLISAPII
AVMFILGTSVVLAFIGNQPINVIGPIPQTFRLAFGNTGIAGFAAQFGIAMLLARAVASSSLIFTGLSRLPMTAGWDNLAP
KWFTRLHPRRRTPVNSILFVAALAMGLILLSLMGAREQEASQLLTAASIVHYAIVYVALFALPLFGSAALRKQLPGWLKL
TAAAGLISSLVALCISAYPVVDVTSRAAFAGKICAVVAISNMGGVLLYRAGRARNTLE
>Mature_458_residues
MREELRKELGLSDLVLAQVLCVVGSSWVGIAAKLGRAHVVFWVVSMLLFYLPLAAVVIYLNRLIPLEGGLYQWAKQGFGE
MAGFLIAWNLWVYAVVVMGAIIFVVPTDLAFMLGGSWTWLPHSRWATLALTGGVMAAITVVAVLGLNIGKWLHNAGSVMI
LTAYVILLGLPVWAMAHGSATHFEALPFEWPKASWFSLAIFGQMTVGALSGFEYVAIMAGECRSAARTIGQSVLISAPII
AVMFILGTSVVLAFIGNQPINVIGPIPQTFRLAFGNTGIAGFAAQFGIAMLLARAVASSSLIFTGLSRLPMTAGWDNLAP
KWFTRLHPRRRTPVNSILFVAALAMGLILLSLMGAREQEASQLLTAASIVHYAIVYVALFALPLFGSAALRKQLPGWLKL
TAAAGLISSLVALCISAYPVVDVTSRAAFAGKICAVVAISNMGGVLLYRAGRARNTLE

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Proline. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48931; Mature: 48931

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREELRKELGLSDLVLAQVLCVVGSSWVGIAAKLGRAHVVFWVVSMLLFYLPLAAVVIYL
CCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
NRLIPLEGGLYQWAKQGFGEMAGFLIAWNLWVYAVVVMGAIIFVVPTDLAFMLGGSWTWL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PHSRWATLALTGGVMAAITVVAVLGLNIGKWLHNAGSVMILTAYVILLGLPVWAMAHGSA
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
THFEALPFEWPKASWFSLAIFGQMTVGALSGFEYVAIMAGECRSAARTIGQSVLISAPII
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
AVMFILGTSVVLAFIGNQPINVIGPIPQTFRLAFGNTGIAGFAAQFGIAMLLARAVASSS
HHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCH
LIFTGLSRLPMTAGWDNLAPKWFTRLHPRRRTPVNSILFVAALAMGLILLSLMGAREQEA
HHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
SQLLTAASIVHYAIVYVALFALPLFGSAALRKQLPGWLKLTAAAGLISSLVALCISAYPV
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCH
VDVTSRAAFAGKICAVVAISNMGGVLLYRAGRARNTLE
HHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MREELRKELGLSDLVLAQVLCVVGSSWVGIAAKLGRAHVVFWVVSMLLFYLPLAAVVIYL
CCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
NRLIPLEGGLYQWAKQGFGEMAGFLIAWNLWVYAVVVMGAIIFVVPTDLAFMLGGSWTWL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
PHSRWATLALTGGVMAAITVVAVLGLNIGKWLHNAGSVMILTAYVILLGLPVWAMAHGSA
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
THFEALPFEWPKASWFSLAIFGQMTVGALSGFEYVAIMAGECRSAARTIGQSVLISAPII
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
AVMFILGTSVVLAFIGNQPINVIGPIPQTFRLAFGNTGIAGFAAQFGIAMLLARAVASSS
HHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCH
LIFTGLSRLPMTAGWDNLAPKWFTRLHPRRRTPVNSILFVAALAMGLILLSLMGAREQEA
HHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
SQLLTAASIVHYAIVYVALFALPLFGSAALRKQLPGWLKLTAAAGLISSLVALCISAYPV
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCH
VDVTSRAAFAGKICAVVAISNMGGVLLYRAGRARNTLE
HHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8366052 [H]