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The map label for this gene is yggB [C]

Identifier: 116621399

GI number: 116621399

Start: 2913969

End: 2914796

Strand: Reverse

Name: yggB [C]

Synonym: Acid_2281

Alternate gene names: 116621399

Gene position: 2914796-2913969 (Counterclockwise)

Preceding gene: 116621400

Following gene: 116621397

Centisome position: 29.25

GC content: 61.23

Gene sequence:

>828_bases
ATGGATTGGAACAACGTTCTTAAAGTGGTCGAGAGCACGGTCACCGGAGTCGGGCTGCAGGTGCTGGGCGCGATCGTCCT
CTACATTGTGGGACGGTGGCTGATCTCATTCGCGGTAGGGATGGTGCAGAAAGGCCTCTCGCGGCAGAGGCTGGAGCCGA
CGCTGTTACGCTTCATCGGCAACACGATCTCGGTGATTCTGAACATCACGCTGGTGATCGCGATCCTGGGTTATTTCGGA
GTGCAGACCACGAGTTTCGCCGCGCTGCTGGCGGGTGCGGGGCTCGCGATCGGGACGGCCTGGGGCGGGCTGCTCTCCAA
TTTTGCGGCCGGGATTTTTCTGGTGGTGCTGCGGCCGTTCAAGGTCGGCGATTTCATTTCGGCGGGCGGGATTACCGGCA
CGGTGGAAGAGGTGGGCCTGTTCGTGACGACCATCGACACGCCGGATAACGTCCGGACGTTCGTGGGCAACAACAAATTG
TTCTCCGACAATATTCAAAATTACTCGGCGAATCCGTACAGGAGGGTGGAGTTGACTGCGCAGATTTCGGGCGCGGCGGA
TCCCAGGCAGGCGATGGCGGCGATCAAGCAGCGGGTCCAGAAGATTCCGAACGTGGCGGCGAAGCCCGAGCCGGATGTGG
CGATCGCGTCGTTCACGCCGGTGGGTCCGGTGCTCGCGATCCGGCCGTACACCAGCAACGAATGTTACTGGCAGGTTTAC
TTCGACACCAATATGGCGATCCGCGAAGTGCTGGGCGATGGCAGCTTCCCGGCGCCGATGCCGGTCTACGGAGTTCAGCA
CATGAACGCGCAGGCGGCAAAGGCGTAG

Upstream 100 bases:

>100_bases
GCATTCCGTATCACGCGCCGGAGCTGATGGCGAAGGTGAAGGAGATGGTGGCGGAGGCGCGGAAGAAGTAAGCTGAACTG
GCGGGAAAGGGGGGATTGAC

Downstream 100 bases:

>100_bases
CTACGCGAGAGTGCTACGCGACGGGGCTCCACATATCGATGGCCCACTTCCACGCGCCGTCTTCCTGTTTCCAGACGACC
ACGTACTTGACTTCGACGGT

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MDWNNVLKVVESTVTGVGLQVLGAIVLYIVGRWLISFAVGMVQKGLSRQRLEPTLLRFIGNTISVILNITLVIAILGYFG
VQTTSFAALLAGAGLAIGTAWGGLLSNFAAGIFLVVLRPFKVGDFISAGGITGTVEEVGLFVTTIDTPDNVRTFVGNNKL
FSDNIQNYSANPYRRVELTAQISGAADPRQAMAAIKQRVQKIPNVAAKPEPDVAIASFTPVGPVLAIRPYTSNECYWQVY
FDTNMAIREVLGDGSFPAPMPVYGVQHMNAQAAKA

Sequences:

>Translated_275_residues
MDWNNVLKVVESTVTGVGLQVLGAIVLYIVGRWLISFAVGMVQKGLSRQRLEPTLLRFIGNTISVILNITLVIAILGYFG
VQTTSFAALLAGAGLAIGTAWGGLLSNFAAGIFLVVLRPFKVGDFISAGGITGTVEEVGLFVTTIDTPDNVRTFVGNNKL
FSDNIQNYSANPYRRVELTAQISGAADPRQAMAAIKQRVQKIPNVAAKPEPDVAIASFTPVGPVLAIRPYTSNECYWQVY
FDTNMAIREVLGDGSFPAPMPVYGVQHMNAQAAKA
>Mature_275_residues
MDWNNVLKVVESTVTGVGLQVLGAIVLYIVGRWLISFAVGMVQKGLSRQRLEPTLLRFIGNTISVILNITLVIAILGYFG
VQTTSFAALLAGAGLAIGTAWGGLLSNFAAGIFLVVLRPFKVGDFISAGGITGTVEEVGLFVTTIDTPDNVRTFVGNNKL
FSDNIQNYSANPYRRVELTAQISGAADPRQAMAAIKQRVQKIPNVAAKPEPDVAIASFTPVGPVLAIRPYTSNECYWQVY
FDTNMAIREVLGDGSFPAPMPVYGVQHMNAQAAKA

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=258, Percent_Identity=29.4573643410853, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787591, Length=210, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 29467; Mature: 29467

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWNNVLKVVESTVTGVGLQVLGAIVLYIVGRWLISFAVGMVQKGLSRQRLEPTLLRFIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
NTISVILNITLVIAILGYFGVQTTSFAALLAGAGLAIGTAWGGLLSNFAAGIFLVVLRPF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
KVGDFISAGGITGTVEEVGLFVTTIDTPDNVRTFVGNNKLFSDNIQNYSANPYRRVELTA
CCCCCHHCCCCCCCHHHCCEEEEEECCCCCHHHHHCCCCEECCCCCCCCCCCEEEEEEEE
QISGAADPRQAMAAIKQRVQKIPNVAAKPEPDVAIASFTPVGPVLAIRPYTSNECYWQVY
EECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCEEEEEE
FDTNMAIREVLGDGSFPAPMPVYGVQHMNAQAAKA
ECCCHHHHHHHCCCCCCCCCCCHHHHHCCCHHCCC
>Mature Secondary Structure
MDWNNVLKVVESTVTGVGLQVLGAIVLYIVGRWLISFAVGMVQKGLSRQRLEPTLLRFIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
NTISVILNITLVIAILGYFGVQTTSFAALLAGAGLAIGTAWGGLLSNFAAGIFLVVLRPF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
KVGDFISAGGITGTVEEVGLFVTTIDTPDNVRTFVGNNKLFSDNIQNYSANPYRRVELTA
CCCCCHHCCCCCCCHHHCCEEEEEECCCCCHHHHHCCCCEECCCCCCCCCCCEEEEEEEE
QISGAADPRQAMAAIKQRVQKIPNVAAKPEPDVAIASFTPVGPVLAIRPYTSNECYWQVY
EECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCEEEEEE
FDTNMAIREVLGDGSFPAPMPVYGVQHMNAQAAKA
ECCCHHHHHHHCCCCCCCCCCCHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]