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The map label for this gene is ucpA [C]

Identifier: 116621359

GI number: 116621359

Start: 2864491

End: 2865309

Strand: Reverse

Name: ucpA [C]

Synonym: Acid_2240

Alternate gene names: 116621359

Gene position: 2865309-2864491 (Counterclockwise)

Preceding gene: 116621360

Following gene: 116621358

Centisome position: 28.75

GC content: 62.88

Gene sequence:

>819_bases
ATGCCTGATGTCTTCGATCTCACCGGACGCGTCGCCGCCATTACCGGCGGCGCCGGCTTACTCGGCGAACAACATGCCCG
CGCCATCGCGCGCGCCGGCGGTTTCCCGGTGCTGCTGGACGTTTCGCCGCACGCGGCCGCCAAGGCCCAACAACTGGCCG
CGGAGTTCGGCGTTTCCGCCTGGGGCCGCCAGACCGATATCACCCAGCCCCGCGACCTCGAAATCTGTCTTCAGGAAATT
CTCGAGCGCTTTGGCCGCATCGATATCCTGGTCAACAACGCGGCCAACAATCCCAAGATGGAAAGCCGCCATGACGTCAA
TTTTTCGCGCTTCGAGAATTTCCCACTGGAGCAGTGGTCGGCCGATCTTTCCGTCGGTCTCACCGGCGCCTTCTTGTGCA
GCCAGGTGCTCGGCGCCGAGATGGCCAGAAGAGGCCGGGGCGTAATTGTGAACGTGGCTTCCGACCTCGCCCTGATCGCG
CCTGACCAGCGCCTCTACCGCCAGCCCGGTCTACCCGAACACCTGCAGCCCGTAAAGCCGGTGACGTACTCCATCGTCAA
ATCCGCCCTGGTCGGTTTGACGCGCTACCTGGCCACCTATTGGGCCGACCGGGGCGTGCGTGTCAACGCCATCTCGCCCG
GAGGCGTCTTCAACGGCCAACCAGAGGAATTTGTCGTGAAGCTCTCGCAACTGATCCCCCTCGGCAGAATGGCGAACCTG
GACGAGTACCAGGGCGCCATTCTCTTTCTGTGCTCCGATGCATCGTCGTACATGACGGGCTCCAATCTGGTTGTCGATGG
CGGGAGGACCTGTTGGTAG

Upstream 100 bases:

>100_bases
CAGGACGGCATCTGGAGTCTGAGGATGGCTCTCGCCGCGAGAGAATCCATCGCTTCCGGCCGAGCCGTCGAGCTAAGCGA
GCAAAGTCAGGATGCCCACC

Downstream 100 bases:

>100_bases
TCTGGCGTAGTATCTCGGATTACCGGTTTCGGCTCGCCAACCTTGACACGCTGCGCTTGCTTGGCCGATCTTTAGAAAGC
ACTCCGCGCGACAGCACCGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MPDVFDLTGRVAAITGGAGLLGEQHARAIARAGGFPVLLDVSPHAAAKAQQLAAEFGVSAWGRQTDITQPRDLEICLQEI
LERFGRIDILVNNAANNPKMESRHDVNFSRFENFPLEQWSADLSVGLTGAFLCSQVLGAEMARRGRGVIVNVASDLALIA
PDQRLYRQPGLPEHLQPVKPVTYSIVKSALVGLTRYLATYWADRGVRVNAISPGGVFNGQPEEFVVKLSQLIPLGRMANL
DEYQGAILFLCSDASSYMTGSNLVVDGGRTCW

Sequences:

>Translated_272_residues
MPDVFDLTGRVAAITGGAGLLGEQHARAIARAGGFPVLLDVSPHAAAKAQQLAAEFGVSAWGRQTDITQPRDLEICLQEI
LERFGRIDILVNNAANNPKMESRHDVNFSRFENFPLEQWSADLSVGLTGAFLCSQVLGAEMARRGRGVIVNVASDLALIA
PDQRLYRQPGLPEHLQPVKPVTYSIVKSALVGLTRYLATYWADRGVRVNAISPGGVFNGQPEEFVVKLSQLIPLGRMANL
DEYQGAILFLCSDASSYMTGSNLVVDGGRTCW
>Mature_271_residues
PDVFDLTGRVAAITGGAGLLGEQHARAIARAGGFPVLLDVSPHAAAKAQQLAAEFGVSAWGRQTDITQPRDLEICLQEIL
ERFGRIDILVNNAANNPKMESRHDVNFSRFENFPLEQWSADLSVGLTGAFLCSQVLGAEMARRGRGVIVNVASDLALIAP
DQRLYRQPGLPEHLQPVKPVTYSIVKSALVGLTRYLATYWADRGVRVNAISPGGVFNGQPEEFVVKLSQLIPLGRMANLD
EYQGAILFLCSDASSYMTGSNLVVDGGRTCW

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=275, Percent_Identity=29.8181818181818, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI32483357, Length=274, Percent_Identity=29.1970802919708, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI19923817, Length=280, Percent_Identity=27.5, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI59889578, Length=215, Percent_Identity=29.3023255813954, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031737, Length=273, Percent_Identity=30.03663003663, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254992, Length=260, Percent_Identity=29.6153846153846, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4758504, Length=273, Percent_Identity=28.2051282051282, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI15277342, Length=210, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI126723750, Length=274, Percent_Identity=25.9124087591241, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI66933014, Length=272, Percent_Identity=24.6323529411765, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=31.5217391304348, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788459, Length=265, Percent_Identity=28.6792452830189, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790717, Length=275, Percent_Identity=28.3636363636364, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789208, Length=276, Percent_Identity=30.0724637681159, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787335, Length=269, Percent_Identity=25.6505576208178, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082160, Length=273, Percent_Identity=28.9377289377289, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787905, Length=272, Percent_Identity=26.8382352941176, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367175, Length=272, Percent_Identity=28.3088235294118, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789057, Length=282, Percent_Identity=26.241134751773, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786812, Length=211, Percent_Identity=30.3317535545024, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=211, Percent_Identity=29.8578199052133, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=268, Percent_Identity=28.3582089552239, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=269, Percent_Identity=30.1115241635688, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=270, Percent_Identity=27.037037037037, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=279, Percent_Identity=29.7491039426523, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=277, Percent_Identity=27.0758122743682, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=281, Percent_Identity=26.6903914590747, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=285, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=284, Percent_Identity=27.112676056338, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=283, Percent_Identity=27.9151943462898, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=216, Percent_Identity=26.3888888888889, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=283, Percent_Identity=26.5017667844523, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=289, Percent_Identity=26.2975778546713, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=284, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=281, Percent_Identity=28.4697508896797, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=277, Percent_Identity=25.6317689530686, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=283, Percent_Identity=25.0883392226148, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=285, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=281, Percent_Identity=25.6227758007117, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=277, Percent_Identity=24.187725631769, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357041, Length=280, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571526, Length=271, Percent_Identity=28.4132841328413, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI23397609, Length=280, Percent_Identity=27.8571428571429, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644339, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17737361, Length=245, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639444, Length=269, Percent_Identity=24.907063197026, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24644337, Length=276, Percent_Identity=27.1739130434783, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29451; Mature: 29320

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDVFDLTGRVAAITGGAGLLGEQHARAIARAGGFPVLLDVSPHAAAKAQQLAAEFGVSA
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCHHH
WGRQTDITQPRDLEICLQEILERFGRIDILVNNAANNPKMESRHDVNFSRFENFPLEQWS
CCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCHHHHC
ADLSVGLTGAFLCSQVLGAEMARRGRGVIVNVASDLALIAPDQRLYRQPGLPEHLQPVKP
CCHHHCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCHHHHHCCCCCHHCCCCCH
VTYSIVKSALVGLTRYLATYWADRGVRVNAISPGGVFNGQPEEFVVKLSQLIPLGRMANL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHCCC
DEYQGAILFLCSDASSYMTGSNLVVDGGRTCW
HHHCCEEEEEECCCCHHCCCCCEEECCCCCCC
>Mature Secondary Structure 
PDVFDLTGRVAAITGGAGLLGEQHARAIARAGGFPVLLDVSPHAAAKAQQLAAEFGVSA
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCHHH
WGRQTDITQPRDLEICLQEILERFGRIDILVNNAANNPKMESRHDVNFSRFENFPLEQWS
CCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCHHHHC
ADLSVGLTGAFLCSQVLGAEMARRGRGVIVNVASDLALIAPDQRLYRQPGLPEHLQPVKP
CCHHHCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCHHHHHCCCCCHHCCCCCH
VTYSIVKSALVGLTRYLATYWADRGVRVNAISPGGVFNGQPEEFVVKLSQLIPLGRMANL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHCCC
DEYQGAILFLCSDASSYMTGSNLVVDGGRTCW
HHHCCEEEEEECCCCHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]