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The map label for this gene is aspC [H]

Identifier: 116621353

GI number: 116621353

Start: 2858750

End: 2859931

Strand: Direct

Name: aspC [H]

Synonym: Acid_2234

Alternate gene names: 116621353

Gene position: 2858750-2859931 (Clockwise)

Preceding gene: 116621350

Following gene: 116621354

Centisome position: 28.69

GC content: 65.06

Gene sequence:

>1182_bases
ATGCCCACGCTTGCCAGTTCTGTAGAGATAGTGCCGCGGTCGCGGATTCGCGAGTTGGCGGAGATTGCGATGACGATGGA
CGGCGTCCTACGCCTTTACTTCGGCGAGAGCAATTTGCCCACGCCGGAGTACATCAAGCAGGCGGCTGTGCGCGCGCTGG
CGGACGGGTTCACGTTCTACACGGAGAACGCGGGATTGCCCTCGCTGCGCCGGGCGCTGGCGGCCAACTACGAGCGCCTG
CACGGGGTGACGCTGGACCCGGGGAGCGAGATCGTGGTGACGGCGTCGGGCGTACAGGCGCTGAACCTGGGAATCCGCTG
CGTGCTCAACCCGGGCGATGAAGCGATCGCGCTGACGCCCGCGTGGCCGAACGGGTCATCCAGCATCATGATGGCGAATG
CGGCGGTCCGGCAGATTCCGCACCCGCTTTGCGGGGAGCGGTACCGGGTGGATTTCGACGCGCTCGAAGCGGCGGTGACG
CCGCGGACGCGGCTGCTGCTGTACACGTCGCCGTCCAATCCGCTGGGCTGGGTGGCGACTGGGGAAGAGCAGCAGGGGCT
GCTCGATTTTGCGCGCCGGCACAATCTGTGGCTAATGGCGGACGAAGTCTACGACCGGCTGTATTATGCCGGCGAGCGGC
TCGGCGATCCGGTGCCCTCCATTCTGCAAAGAGCCACGCGGGAGGACGCGGTAATGGTAGTGCACTCGTTCTCCAAGAGT
TACTGCATGACGGGTTGGCGCGTGGGCTGGCTGGTGGCGCGGCGCGACCTGGCGGCGAAGGCGACGCAACTCAACGAGTT
CATTATTTCGCACGCGCCCACGTTCGCGCAGAAGGCGGCGGAAACGGCGCTGGCAGAAGGCGAACCCGAACTGGCGCGCA
TGCTGGAGCGGCTCAAGGAAAATCGCGATCTCTGCCTGGAGGCGCTGCGCGGCCTGCCGGGAATTACGGTGCCGAAGCCG
GATGGAGCGTTCTATCTTTTCCCGCGCGTGGAGGGGATGACGGATTCCTTCGGATTCTGCCGCGGGCTGCTGGAGGAAAC
GCGCGTCGGGTTGGCGCCGGGAGTGGCCTTCGGCGAAGGCGGCGAAGGTTCTTTCCGCATCTGCTATGCGGCGGAACGCA
GTATTCTGGAACCTGCAATGGAGCGGTTGACCAAATTCCTGCGTAAGGGAGCTCACAGATGA

Upstream 100 bases:

>100_bases
GAACTCGTCGGTGATGGCTGCGATGGGGTAGTGTGCTGGCATGAAAGCTCCATTATAGAGGGGCGCGAAGAGGGAAAACC
AAGAGTGCGAGAATAGCAAG

Downstream 100 bases:

>100_bases
TCAAGGGGTTCAAGGAGTTTCTGTTAAAGAACAATGTGTTGGCACTGGCGGTCGCGGTGATCGTCGGCGGCGCGGTTGGC
AAGGTGGTATCCTCGCTGGC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MPTLASSVEIVPRSRIRELAEIAMTMDGVLRLYFGESNLPTPEYIKQAAVRALADGFTFYTENAGLPSLRRALAANYERL
HGVTLDPGSEIVVTASGVQALNLGIRCVLNPGDEAIALTPAWPNGSSSIMMANAAVRQIPHPLCGERYRVDFDALEAAVT
PRTRLLLYTSPSNPLGWVATGEEQQGLLDFARRHNLWLMADEVYDRLYYAGERLGDPVPSILQRATREDAVMVVHSFSKS
YCMTGWRVGWLVARRDLAAKATQLNEFIISHAPTFAQKAAETALAEGEPELARMLERLKENRDLCLEALRGLPGITVPKP
DGAFYLFPRVEGMTDSFGFCRGLLEETRVGLAPGVAFGEGGEGSFRICYAAERSILEPAMERLTKFLRKGAHR

Sequences:

>Translated_393_residues
MPTLASSVEIVPRSRIRELAEIAMTMDGVLRLYFGESNLPTPEYIKQAAVRALADGFTFYTENAGLPSLRRALAANYERL
HGVTLDPGSEIVVTASGVQALNLGIRCVLNPGDEAIALTPAWPNGSSSIMMANAAVRQIPHPLCGERYRVDFDALEAAVT
PRTRLLLYTSPSNPLGWVATGEEQQGLLDFARRHNLWLMADEVYDRLYYAGERLGDPVPSILQRATREDAVMVVHSFSKS
YCMTGWRVGWLVARRDLAAKATQLNEFIISHAPTFAQKAAETALAEGEPELARMLERLKENRDLCLEALRGLPGITVPKP
DGAFYLFPRVEGMTDSFGFCRGLLEETRVGLAPGVAFGEGGEGSFRICYAAERSILEPAMERLTKFLRKGAHR
>Mature_392_residues
PTLASSVEIVPRSRIRELAEIAMTMDGVLRLYFGESNLPTPEYIKQAAVRALADGFTFYTENAGLPSLRRALAANYERLH
GVTLDPGSEIVVTASGVQALNLGIRCVLNPGDEAIALTPAWPNGSSSIMMANAAVRQIPHPLCGERYRVDFDALEAAVTP
RTRLLLYTSPSNPLGWVATGEEQQGLLDFARRHNLWLMADEVYDRLYYAGERLGDPVPSILQRATREDAVMVVHSFSKSY
CMTGWRVGWLVARRDLAAKATQLNEFIISHAPTFAQKAAETALAEGEPELARMLERLKENRDLCLEALRGLPGITVPKPD
GAFYLFPRVEGMTDSFGFCRGLLEETRVGLAPGVAFGEGGEGSFRICYAAERSILEPAMERLTKFLRKGAHR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=388, Percent_Identity=25, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI56713254, Length=388, Percent_Identity=25, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI95147551, Length=407, Percent_Identity=22.8501228501229, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI169881279, Length=407, Percent_Identity=22.8501228501229, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4507369, Length=372, Percent_Identity=24.1935483870968, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4885351, Length=347, Percent_Identity=25.9365994236311, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI169881281, Length=267, Percent_Identity=20.5992509363296, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1786816, Length=389, Percent_Identity=26.9922879177378, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788722, Length=336, Percent_Identity=27.3809523809524, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788627, Length=400, Percent_Identity=27.5, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787710, Length=336, Percent_Identity=27.6785714285714, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1790797, Length=305, Percent_Identity=26.5573770491803, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=25.3968253968254, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=374, Percent_Identity=25.668449197861, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=374, Percent_Identity=25.668449197861, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=366, Percent_Identity=21.3114754098361, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71981209, Length=370, Percent_Identity=22.972972972973, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=359, Percent_Identity=24.2339832869081, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573069, Length=359, Percent_Identity=24.2339832869081, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646114, Length=359, Percent_Identity=24.2339832869081, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573067, Length=359, Percent_Identity=24.2339832869081, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573065, Length=359, Percent_Identity=24.2339832869081, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=22.2520107238606, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43274; Mature: 43143

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLASSVEIVPRSRIRELAEIAMTMDGVLRLYFGESNLPTPEYIKQAAVRALADGFTFY
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCEEE
TENAGLPSLRRALAANYERLHGVTLDPGSEIVVTASGVQALNLGIRCVLNPGDEAIALTP
ECCCCCHHHHHHHHHCHHHHCCCEECCCCCEEEEECCCEEECCCEEEEECCCCCEEEEEE
AWPNGSSSIMMANAAVRQIPHPLCGERYRVDFDALEAAVTPRTRLLLYTSPSNPLGWVAT
CCCCCCCCEEEEHHHHHHCCCCCCCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCEEEC
GEEQQGLLDFARRHNLWLMADEVYDRLYYAGERLGDPVPSILQRATREDAVMVVHSFSKS
CCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEHHCCH
YCMTGWRVGWLVARRDLAAKATQLNEFIISHAPTFAQKAAETALAEGEPELARMLERLKE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
NRDLCLEALRGLPGITVPKPDGAFYLFPRVEGMTDSFGFCRGLLEETRVGLAPGVAFGEG
CHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEECCC
GEGSFRICYAAERSILEPAMERLTKFLRKGAHR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PTLASSVEIVPRSRIRELAEIAMTMDGVLRLYFGESNLPTPEYIKQAAVRALADGFTFY
CCCCCHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCCEEE
TENAGLPSLRRALAANYERLHGVTLDPGSEIVVTASGVQALNLGIRCVLNPGDEAIALTP
ECCCCCHHHHHHHHHCHHHHCCCEECCCCCEEEEECCCEEECCCEEEEECCCCCEEEEEE
AWPNGSSSIMMANAAVRQIPHPLCGERYRVDFDALEAAVTPRTRLLLYTSPSNPLGWVAT
CCCCCCCCEEEEHHHHHHCCCCCCCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCEEEC
GEEQQGLLDFARRHNLWLMADEVYDRLYYAGERLGDPVPSILQRATREDAVMVVHSFSKS
CCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEHHCCH
YCMTGWRVGWLVARRDLAAKATQLNEFIISHAPTFAQKAAETALAEGEPELARMLERLKE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
NRDLCLEALRGLPGITVPKPDGAFYLFPRVEGMTDSFGFCRGLLEETRVGLAPGVAFGEG
CHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEECCC
GEGSFRICYAAERSILEPAMERLTKFLRKGAHR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]