Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 116621333

GI number: 116621333

Start: 2835677

End: 2838091

Strand: Direct

Name: macB [H]

Synonym: Acid_2214

Alternate gene names: 116621333

Gene position: 2835677-2838091 (Clockwise)

Preceding gene: 116621332

Following gene: 116621335

Centisome position: 28.45

GC content: 65.96

Gene sequence:

>2415_bases
ATGCTCAGCTCGTTCATGCGTGATTTGCGGTATGCCTTACGGACTCTGGCGCGAAATCCGGGGTTCGCGTGCGTTTCGAT
TCTGGCGCTGGCGCTGGGAGTGGGGGCGAACAGCGCGATCTTCACTGTGGTGCAATCCGTGCTGCTGCGGCCGCTGCCGT
TCCGGAGGTCGGACGAGCTCATCGTGGTCCGGGAGCGCAACCTGAAGGCTGGTTTTCCGCAGTTTTCGCTATCGCCGGGG
AACTATGTGGATTACCGTGATCACAATCACACGCTCTCGGGTTTCACTGCGTTTAGCCGGCTGGGCGTGAACCTGTCGGG
CGGAGCGGAGCCGGAACGCTTGCGCGGCGCGAGGGTGACCAACGAGTTCTTCCATGTGCTGGGCGTGCAGCCTTCGGTAG
GAAGGGCGTTCACCGCGGCGGAAGGCCAGTTCGGAGCGCAGAAGGTGGTGATTCTGAGCGACGGCCTTTGGCAGCGGCGA
TTCGGCGGCGCGAAAGACGTGCTCGGGCGGCAATTGAAGATGAACGAGGAGTTGTACACCGTGGTCGGCGTGATGCCGCC
GGATTTCTCATTCCCGGCGCGCGCGGAGATATGGACTCCCCTGGCGCTGAACGCGCAGAACTGGCAGCAGCGCGGCGGAC
ACTACCTGAGCGGCGTCGCGCGCCTGAAGCTGGGCACGTCGCTGGCGGCGGCGGAAGCCGACTTGAACAGTATCGCGGCG
CGCGCCGAGAAGGCATATCCGAACTCCAACACCGGTTGGGATACCACCAGCACGGGGCTGCAGGAATCGATGGTCGGCAA
GATACGGCCGCTGGTGATGACGCTGATGGCGGCGGTGGGATTCGTGCTGCTGATCGCGTGCGTGAACCTGGCGAACCTGC
TGCTTTCGCGCTCGGCGGCGCGGCGGCGGGAGATCGGCATACGCAATGCGCTGGGTGCGGGGCGCGGCAGACTGATTCGT
CAACTGCTGACGGAGAGCGTGCTGCTCTCGGGTCTCGGAGCGGCGTTGGGGCTGTTGCTGGCGTGGGGCGGGACTCGTCT
GCTGGTGAACCTCAATCCGAATATTCTGCCCCGCGCGAAGGAGATTTCGCTGGATGCGAGCGTGGTGCTGTTCACCATCG
CGATCGCGGGCCTCACCGGCATTCTGTTCGGTCTGGCGCCGGCGATCCACATGGCGAAAACGGACCTGGCGGCGGCCTTC
CGAGAAGGCGGGCGCGGAAACTCGATCGGGTTCCGGCGTAATACGCTACGCTCTGTGCTGGTGATCGGAGAAGTGGCGCT
GGCCCTGGTGCTGCTGTGCGGAGCCGGATTGCTGATGCGCAGTTTTTATCACCTGCAGAGCATGGACCCGGGGTTCGATC
CGCACGACGTGCTGACCTTCCGCACCAACCTTCCGGGCGCGAAATACAAGACCGATGAGCAGCAGGAGGCCTTCTACACG
CGTGCGCTGGACCGCATCCGTGCGCTGCCCGGAGTCACCGTGGCCGGCGCGGCGCAAATATTCCCGCTGGCGGGCGACGA
TTATATTCTGACCTTCGTACAGGTGGGCAAGCCTCCGGTGCCGGTGGGCAACCAGCCCTCGGCGGCCTTCTACTCGGCCA
CGCCGGGATATTTCGGCGCGCTGCGGATTCCGATTAAGGCGGGCCGCGATTTCACGGCTCGCGACAACGCCGCGGCGCCG
CCGGTGGCGATCATCAGCGAATCCATGGCGCGCCAGTTCTATGCGAACGAGAATCCGCTGGGGCAGCGCCTCCAGATCGG
CGGGGGAGACGACAAGCCGGCGGAGATCGTGGGCATTGCAGGGGACGTGCGCGATAACGAGTTGGAATCGAAGGGGCGCG
CGGCGATGTACCGGCCGGCGGCACAGGCGCCGTTCGGCTCGATGTACTTCGGGGTGCGCACGGAGCGCGATCCGGCGGCG
GCGATCGCGGGAGTGCGCGCGGCGATCCGCGAGATGGACGCGGAGCTGCCGCTGGACGCGGTGGGCACGGTGGACGCGCT
GGTTGAGACTTCGCTTTCGCAGCGCCGCTTCGCCATGCTGCTGATGGGCATTTTCGCGGGCCTCGCGCTGGTGCTGGCGA
TGGTCGGGATCTACGGCGTGATGGCCTACTCGGTCACACAGGCCACGCAGGAAATCGGCATCCGGATGGCGCTGGGCGCG
GGGCGCGGGGACGTGGTGCGGATGGTGCTGGGGTACGGCGCGCTGCTGATGTCGGCGGGGATTGTCGCGGGCGTGGCCGC
CTCATTAGGCGCGGGGAGACTGCTGGCGTCGCAACTCTTTGAAGTGAAGTCCTACGACCCGGTGACGTACGCGCTGGTGG
GGTCGGTACTGATTGCGACGGCGCTGGCGGCGTGCCTGATTCCGGCCTTCCGCGCGATGCGGGTGGACCCGGTGATCGCG
CTGCGGAACGAATAA

Upstream 100 bases:

>100_bases
CGTATTTTGTGATGCGGAAAGTGGGCGGCGAGTGGCGGATCGCGGTGATGCGGATGCCGTAAGCTATCCTCAGGGCGCGG
GGAGCGTCTAATGGAAAGCT

Downstream 100 bases:

>100_bases
TCGAAATTCAGGCGAGAGTCTCCCACGCTTCTGCCGGTGGCATCGCCGACAGACATTTCGAACCGCGCTTCCTGTGCGCT
GACCTGGTGAAGGTGCAATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 804; Mature: 804

Protein sequence:

>804_residues
MLSSFMRDLRYALRTLARNPGFACVSILALALGVGANSAIFTVVQSVLLRPLPFRRSDELIVVRERNLKAGFPQFSLSPG
NYVDYRDHNHTLSGFTAFSRLGVNLSGGAEPERLRGARVTNEFFHVLGVQPSVGRAFTAAEGQFGAQKVVILSDGLWQRR
FGGAKDVLGRQLKMNEELYTVVGVMPPDFSFPARAEIWTPLALNAQNWQQRGGHYLSGVARLKLGTSLAAAEADLNSIAA
RAEKAYPNSNTGWDTTSTGLQESMVGKIRPLVMTLMAAVGFVLLIACVNLANLLLSRSAARRREIGIRNALGAGRGRLIR
QLLTESVLLSGLGAALGLLLAWGGTRLLVNLNPNILPRAKEISLDASVVLFTIAIAGLTGILFGLAPAIHMAKTDLAAAF
REGGRGNSIGFRRNTLRSVLVIGEVALALVLLCGAGLLMRSFYHLQSMDPGFDPHDVLTFRTNLPGAKYKTDEQQEAFYT
RALDRIRALPGVTVAGAAQIFPLAGDDYILTFVQVGKPPVPVGNQPSAAFYSATPGYFGALRIPIKAGRDFTARDNAAAP
PVAIISESMARQFYANENPLGQRLQIGGGDDKPAEIVGIAGDVRDNELESKGRAAMYRPAAQAPFGSMYFGVRTERDPAA
AIAGVRAAIREMDAELPLDAVGTVDALVETSLSQRRFAMLLMGIFAGLALVLAMVGIYGVMAYSVTQATQEIGIRMALGA
GRGDVVRMVLGYGALLMSAGIVAGVAASLGAGRLLASQLFEVKSYDPVTYALVGSVLIATALAACLIPAFRAMRVDPVIA
LRNE

Sequences:

>Translated_804_residues
MLSSFMRDLRYALRTLARNPGFACVSILALALGVGANSAIFTVVQSVLLRPLPFRRSDELIVVRERNLKAGFPQFSLSPG
NYVDYRDHNHTLSGFTAFSRLGVNLSGGAEPERLRGARVTNEFFHVLGVQPSVGRAFTAAEGQFGAQKVVILSDGLWQRR
FGGAKDVLGRQLKMNEELYTVVGVMPPDFSFPARAEIWTPLALNAQNWQQRGGHYLSGVARLKLGTSLAAAEADLNSIAA
RAEKAYPNSNTGWDTTSTGLQESMVGKIRPLVMTLMAAVGFVLLIACVNLANLLLSRSAARRREIGIRNALGAGRGRLIR
QLLTESVLLSGLGAALGLLLAWGGTRLLVNLNPNILPRAKEISLDASVVLFTIAIAGLTGILFGLAPAIHMAKTDLAAAF
REGGRGNSIGFRRNTLRSVLVIGEVALALVLLCGAGLLMRSFYHLQSMDPGFDPHDVLTFRTNLPGAKYKTDEQQEAFYT
RALDRIRALPGVTVAGAAQIFPLAGDDYILTFVQVGKPPVPVGNQPSAAFYSATPGYFGALRIPIKAGRDFTARDNAAAP
PVAIISESMARQFYANENPLGQRLQIGGGDDKPAEIVGIAGDVRDNELESKGRAAMYRPAAQAPFGSMYFGVRTERDPAA
AIAGVRAAIREMDAELPLDAVGTVDALVETSLSQRRFAMLLMGIFAGLALVLAMVGIYGVMAYSVTQATQEIGIRMALGA
GRGDVVRMVLGYGALLMSAGIVAGVAASLGAGRLLASQLFEVKSYDPVTYALVGSVLIATALAACLIPAFRAMRVDPVIA
LRNE
>Mature_804_residues
MLSSFMRDLRYALRTLARNPGFACVSILALALGVGANSAIFTVVQSVLLRPLPFRRSDELIVVRERNLKAGFPQFSLSPG
NYVDYRDHNHTLSGFTAFSRLGVNLSGGAEPERLRGARVTNEFFHVLGVQPSVGRAFTAAEGQFGAQKVVILSDGLWQRR
FGGAKDVLGRQLKMNEELYTVVGVMPPDFSFPARAEIWTPLALNAQNWQQRGGHYLSGVARLKLGTSLAAAEADLNSIAA
RAEKAYPNSNTGWDTTSTGLQESMVGKIRPLVMTLMAAVGFVLLIACVNLANLLLSRSAARRREIGIRNALGAGRGRLIR
QLLTESVLLSGLGAALGLLLAWGGTRLLVNLNPNILPRAKEISLDASVVLFTIAIAGLTGILFGLAPAIHMAKTDLAAAF
REGGRGNSIGFRRNTLRSVLVIGEVALALVLLCGAGLLMRSFYHLQSMDPGFDPHDVLTFRTNLPGAKYKTDEQQEAFYT
RALDRIRALPGVTVAGAAQIFPLAGDDYILTFVQVGKPPVPVGNQPSAAFYSATPGYFGALRIPIKAGRDFTARDNAAAP
PVAIISESMARQFYANENPLGQRLQIGGGDDKPAEIVGIAGDVRDNELESKGRAAMYRPAAQAPFGSMYFGVRTERDPAA
AIAGVRAAIREMDAELPLDAVGTVDALVETSLSQRRFAMLLMGIFAGLALVLAMVGIYGVMAYSVTQATQEIGIRMALGA
GRGDVVRMVLGYGALLMSAGIVAGVAASLGAGRLLASQLFEVKSYDPVTYALVGSVLIATALAACLIPAFRAMRVDPVIA
LRNE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=283, Percent_Identity=26.5017667844523, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 85702; Mature: 85702

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSFMRDLRYALRTLARNPGFACVSILALALGVGANSAIFTVVQSVLLRPLPFRRSDEL
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCE
IVVRERNLKAGFPQFSLSPGNYVDYRDHNHTLSGFTAFSRLGVNLSGGAEPERLRGARVT
EEEEECCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCHHH
NEFFHVLGVQPSVGRAFTAAEGQFGAQKVVILSDGLWQRRFGGAKDVLGRQLKMNEELYT
HHHHHHHCCCCCCCCEEECCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHCCCCEEE
VVGVMPPDFSFPARAEIWTPLALNAQNWQQRGGHYLSGVARLKLGTSLAAAEADLNSIAA
EEECCCCCCCCCCCCCCCCCEEECCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
RAEKAYPNSNTGWDTTSTGLQESMVGKIRPLVMTLMAAVGFVLLIACVNLANLLLSRSAA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRREIGIRNALGAGRGRLIRQLLTESVLLSGLGAALGLLLAWGGTRLLVNLNPNILPRAK
HHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
EISLDASVVLFTIAIAGLTGILFGLAPAIHMAKTDLAAAFREGGRGNSIGFRRNTLRSVL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VIGEVALALVLLCGAGLLMRSFYHLQSMDPGFDPHDVLTFRTNLPGAKYKTDEQQEAFYT
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHH
RALDRIRALPGVTVAGAAQIFPLAGDDYILTFVQVGKPPVPVGNQPSAAFYSATPGYFGA
HHHHHHHHCCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCCCEE
LRIPIKAGRDFTARDNAAAPPVAIISESMARQFYANENPLGQRLQIGGGDDKPAEIVGIA
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEE
GDVRDNELESKGRAAMYRPAAQAPFGSMYFGVRTERDPAAAIAGVRAAIREMDAELPLDA
CCCCCCHHHHCCCEEEECCCCCCCCCCEEECEECCCCHHHHHHHHHHHHHHHCCCCCCHH
VGTVDALVETSLSQRRFAMLLMGIFAGLALVLAMVGIYGVMAYSVTQATQEIGIRMALGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GRGDVVRMVLGYGALLMSAGIVAGVAASLGAGRLLASQLFEVKSYDPVTYALVGSVLIAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALAACLIPAFRAMRVDPVIALRNE
HHHHHHHHHHHHHCCCCEEEECCC
>Mature Secondary Structure
MLSSFMRDLRYALRTLARNPGFACVSILALALGVGANSAIFTVVQSVLLRPLPFRRSDEL
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCE
IVVRERNLKAGFPQFSLSPGNYVDYRDHNHTLSGFTAFSRLGVNLSGGAEPERLRGARVT
EEEEECCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCHHH
NEFFHVLGVQPSVGRAFTAAEGQFGAQKVVILSDGLWQRRFGGAKDVLGRQLKMNEELYT
HHHHHHHCCCCCCCCEEECCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHCCCCEEE
VVGVMPPDFSFPARAEIWTPLALNAQNWQQRGGHYLSGVARLKLGTSLAAAEADLNSIAA
EEECCCCCCCCCCCCCCCCCEEECCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
RAEKAYPNSNTGWDTTSTGLQESMVGKIRPLVMTLMAAVGFVLLIACVNLANLLLSRSAA
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRREIGIRNALGAGRGRLIRQLLTESVLLSGLGAALGLLLAWGGTRLLVNLNPNILPRAK
HHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
EISLDASVVLFTIAIAGLTGILFGLAPAIHMAKTDLAAAFREGGRGNSIGFRRNTLRSVL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VIGEVALALVLLCGAGLLMRSFYHLQSMDPGFDPHDVLTFRTNLPGAKYKTDEQQEAFYT
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHH
RALDRIRALPGVTVAGAAQIFPLAGDDYILTFVQVGKPPVPVGNQPSAAFYSATPGYFGA
HHHHHHHHCCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCCCEE
LRIPIKAGRDFTARDNAAAPPVAIISESMARQFYANENPLGQRLQIGGGDDKPAEIVGIA
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEE
GDVRDNELESKGRAAMYRPAAQAPFGSMYFGVRTERDPAAAIAGVRAAIREMDAELPLDA
CCCCCCHHHHCCCEEEECCCCCCCCCCEEECEECCCCHHHHHHHHHHHHHHHCCCCCCHH
VGTVDALVETSLSQRRFAMLLMGIFAGLALVLAMVGIYGVMAYSVTQATQEIGIRMALGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
GRGDVVRMVLGYGALLMSAGIVAGVAASLGAGRLLASQLFEVKSYDPVTYALVGSVLIAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALAACLIPAFRAMRVDPVIALRNE
HHHHHHHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA