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The map label for this gene is tap [H]

Identifier: 116621257

GI number: 116621257

Start: 2737065

End: 2738504

Strand: Reverse

Name: tap [H]

Synonym: Acid_2138

Alternate gene names: 116621257

Gene position: 2738504-2737065 (Counterclockwise)

Preceding gene: 116621258

Following gene: 116621255

Centisome position: 27.48

GC content: 59.44

Gene sequence:

>1440_bases
ATGTTCAAAAATAGAGCCTTAAAACAGAAACTGATTGGCGGACTCGGCCTGGCGATGTTGTCGATGGCGGTATTGGCGGT
CTTCTCCGTCATCCAGATTCGCGGACTCGGCTCCGTAGTGACGAGAGCCGTACAGATCCATGAGTTGACCCGCATGGGCT
CTCTTGCTTCCGATATGATCGGTCTGGAACGGGGGATCGTGCTGTACTCGATCTTCGAAGATAAGGTCAATCTCCCGCTG
TTCAAGAGGCGATTAGAAGATTCTTCGAAGTCCTTCTCCGCGGGGCTCGATACTGTCAGAGTCGCCGTTACCTCCGAAAG
TGCCGGCAAGAGCCTGGTGACACTCCGATCCAAGTACGAGGCATGGTCTGCCATGCATAAGGAGATCGTCGGCTACCTGG
AGAGACAGCAGGTGGATCTGGCACAAGCCAAGCTGGCAGCGCCGGACTTCATCTCCGCAGTGGACGAAATGCGGAGACTG
GCCGACGAAATGTCCGACCGGGAGGCCAAACGGCTCTCAAGCGAAGCCTCCTCCGCCGAGATCGTCTCCCTGGTAGGGTT
CGGAGTGTTGACGCTGTTATCGTTCGGAATCTGCGCGCTGGTGCTGGTTTACGTCCGGGGTGTGAGCGAGAGCCTCGGCA
GGTTGACGGATTCGCTGGCGGGCAACTCCCAGCAGGTCGAGATACTCTCCTCGGGCGTACAAACGGCCAGCCAGTCCCTG
GCCCAAGGGAGCTCGCAGCAGGCTGCTTCGCTAGAGGAGACATCCGCCTCTACCGAGGAGATCACCGCCGTGACACGCCG
GAATGTCGAGAATTCCCAAACCGCCAGCGAGGTCATGGCCGAAGTGGACAGCCATATAAAAGGCGGCAATCGCACGCTGG
AGTTGATGATGGTCTCGATGAATGAGATCAATGCTTCCAGCGGCAAGATCTCGAAAATCATCAAGGTCATCGACGAGATC
GCATTCCAGACGAATATCCTGGCGCTGAACGCCGCTGTGGAAGCAGCCCGGGCCGGAGAGGCGGGCTTGGGATTCGCCGT
AGTGGCCGACGAAGTGAGAAACCTGGCCCAGCGTTCGGCACAAGCGGCCAAAGACACAGCGGAAATGATCGAGGAGTCAA
TCGGGACCTCAAATGAGGGCAAGGCGAAGCTGGATGAGCTGAGTGAGATGATACGAGCCATCACGCAGAGCGCGGCCCAA
GTCAAGACGCTGGTCGATGGGGTAAGCCACGGAAGCCGCGAACAGGCGCGGGGCATTGAGCAGATCGCGGGAGCGGTCAC
GCTGATGGAGCGGATGACGCAATCCACGGCCACCAGCGCGCAGGAGAGCGCCTCTGCCAGCGACAACCTCGCGGGGCAGG
CGCGAGGCTTAAACGAAGTCGTGTTGCAACTCAGGCGCCTAGTGGATGGCGGGGGCGAACCGGCGATTCCGCCACGCTGA

Upstream 100 bases:

>100_bases
TCGTTCGACTTGCCGATGTGACCGATGCCGTGAGAGTAGTCACGGTCGATGGGATTGCCGCTGGTCAACCCGGTTACAAG
ATCAAGGCGGGAAAGTAGCG

Downstream 100 bases:

>100_bases
GGCCTATTTAAAGGTCAGGGTCAGGTCTACCAGGTTGGTATCGCCGCGGAGGGAGAGTTTCGAATCGAAGCCTTTCACGG
AGTTACCGAGGAAATCGAGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-IV; Dipeptide chemoreceptor protein [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MFKNRALKQKLIGGLGLAMLSMAVLAVFSVIQIRGLGSVVTRAVQIHELTRMGSLASDMIGLERGIVLYSIFEDKVNLPL
FKRRLEDSSKSFSAGLDTVRVAVTSESAGKSLVTLRSKYEAWSAMHKEIVGYLERQQVDLAQAKLAAPDFISAVDEMRRL
ADEMSDREAKRLSSEASSAEIVSLVGFGVLTLLSFGICALVLVYVRGVSESLGRLTDSLAGNSQQVEILSSGVQTASQSL
AQGSSQQAASLEETSASTEEITAVTRRNVENSQTASEVMAEVDSHIKGGNRTLELMMVSMNEINASSGKISKIIKVIDEI
AFQTNILALNAAVEAARAGEAGLGFAVVADEVRNLAQRSAQAAKDTAEMIEESIGTSNEGKAKLDELSEMIRAITQSAAQ
VKTLVDGVSHGSREQARGIEQIAGAVTLMERMTQSTATSAQESASASDNLAGQARGLNEVVLQLRRLVDGGGEPAIPPR

Sequences:

>Translated_479_residues
MFKNRALKQKLIGGLGLAMLSMAVLAVFSVIQIRGLGSVVTRAVQIHELTRMGSLASDMIGLERGIVLYSIFEDKVNLPL
FKRRLEDSSKSFSAGLDTVRVAVTSESAGKSLVTLRSKYEAWSAMHKEIVGYLERQQVDLAQAKLAAPDFISAVDEMRRL
ADEMSDREAKRLSSEASSAEIVSLVGFGVLTLLSFGICALVLVYVRGVSESLGRLTDSLAGNSQQVEILSSGVQTASQSL
AQGSSQQAASLEETSASTEEITAVTRRNVENSQTASEVMAEVDSHIKGGNRTLELMMVSMNEINASSGKISKIIKVIDEI
AFQTNILALNAAVEAARAGEAGLGFAVVADEVRNLAQRSAQAAKDTAEMIEESIGTSNEGKAKLDELSEMIRAITQSAAQ
VKTLVDGVSHGSREQARGIEQIAGAVTLMERMTQSTATSAQESASASDNLAGQARGLNEVVLQLRRLVDGGGEPAIPPR
>Mature_479_residues
MFKNRALKQKLIGGLGLAMLSMAVLAVFSVIQIRGLGSVVTRAVQIHELTRMGSLASDMIGLERGIVLYSIFEDKVNLPL
FKRRLEDSSKSFSAGLDTVRVAVTSESAGKSLVTLRSKYEAWSAMHKEIVGYLERQQVDLAQAKLAAPDFISAVDEMRRL
ADEMSDREAKRLSSEASSAEIVSLVGFGVLTLLSFGICALVLVYVRGVSESLGRLTDSLAGNSQQVEILSSGVQTASQSL
AQGSSQQAASLEETSASTEEITAVTRRNVENSQTASEVMAEVDSHIKGGNRTLELMMVSMNEINASSGKISKIIKVIDEI
AFQTNILALNAAVEAARAGEAGLGFAVVADEVRNLAQRSAQAAKDTAEMIEESIGTSNEGKAKLDELSEMIRAITQSAAQ
VKTLVDGVSHGSREQARGIEQIAGAVTLMERMTQSTATSAQESASASDNLAGQARGLNEVVLQLRRLVDGGGEPAIPPR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=245, Percent_Identity=44.8979591836735, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI2367378, Length=205, Percent_Identity=46.8292682926829, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1788195, Length=238, Percent_Identity=41.5966386554622, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1787690, Length=278, Percent_Identity=37.410071942446, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1789453, Length=261, Percent_Identity=36.0153256704981, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 50935; Mature: 50935

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNRALKQKLIGGLGLAMLSMAVLAVFSVIQIRGLGSVVTRAVQIHELTRMGSLASDMI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
GLERGIVLYSIFEDKVNLPLFKRRLEDSSKSFSAGLDTVRVAVTSESAGKSLVTLRSKYE
HHHCCHHEEEEHHCCCCCHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHH
AWSAMHKEIVGYLERQQVDLAQAKLAAPDFISAVDEMRRLADEMSDREAKRLSSEASSAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
IVSLVGFGVLTLLSFGICALVLVYVRGVSESLGRLTDSLAGNSQQVEILSSGVQTASQSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AQGSSQQAASLEETSASTEEITAVTRRNVENSQTASEVMAEVDSHIKGGNRTLELMMVSM
HCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEHEEEHH
NEINASSGKISKIIKVIDEIAFQTNILALNAAVEAARAGEAGLGFAVVADEVRNLAQRSA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
QAAKDTAEMIEESIGTSNEGKAKLDELSEMIRAITQSAAQVKTLVDGVSHGSREQARGIE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QIAGAVTLMERMTQSTATSAQESASASDNLAGQARGLNEVVLQLRRLVDGGGEPAIPPR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFKNRALKQKLIGGLGLAMLSMAVLAVFSVIQIRGLGSVVTRAVQIHELTRMGSLASDMI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
GLERGIVLYSIFEDKVNLPLFKRRLEDSSKSFSAGLDTVRVAVTSESAGKSLVTLRSKYE
HHHCCHHEEEEHHCCCCCHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHH
AWSAMHKEIVGYLERQQVDLAQAKLAAPDFISAVDEMRRLADEMSDREAKRLSSEASSAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
IVSLVGFGVLTLLSFGICALVLVYVRGVSESLGRLTDSLAGNSQQVEILSSGVQTASQSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AQGSSQQAASLEETSASTEEITAVTRRNVENSQTASEVMAEVDSHIKGGNRTLELMMVSM
HCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEHEEEHH
NEINASSGKISKIIKVIDEIAFQTNILALNAAVEAARAGEAGLGFAVVADEVRNLAQRSA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
QAAKDTAEMIEESIGTSNEGKAKLDELSEMIRAITQSAAQVKTLVDGVSHGSREQARGIE
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QIAGAVTLMERMTQSTATSAQESASASDNLAGQARGLNEVVLQLRRLVDGGGEPAIPPR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6305515; 9097040; 9278503 [H]