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The map label for this gene is qheDH [H]

Identifier: 116621231

GI number: 116621231

Start: 2700898

End: 2702430

Strand: Reverse

Name: qheDH [H]

Synonym: Acid_2112

Alternate gene names: 116621231

Gene position: 2702430-2700898 (Counterclockwise)

Preceding gene: 116621232

Following gene: 116621229

Centisome position: 27.12

GC content: 62.04

Gene sequence:

>1533_bases
ATGCGCCTCGAAACCAGAATCGCGACCCTGCTCTGCGCCGCCGCCCTTCCGATCGGCGCACAGTCTGTAGATCCGAAACT
GCTGCTCAGCCCGCCCACGAACGCGTGGCTCACGTACCACGGCGACTACACCGGGGAGCGGCACAGCAAGCTCAGCGAGA
TCACGCCGGAGAACATCTCGAAGCTCAAACAGGTCTGGAAGTTTCAGTCGAGCCAGCAGCTCAAGGCGTCGCCGATCGTG
GCGAACGGGATGATCTACATCACGGCTCCCGACAATCTCTGGGCCATCGATGCCCACAGCGGCAAGGAAGTCTGGCATCA
CCAGCACACCAAGAACAATGCCTTCCACATCGGGCACCGCGGCGCGGCGATTTACAAGGACACCGTCTACCTCACCACGC
CGGATTGCCACCTGCTCGCCTTGAACTCCAGGAACGGCGAGGTCAAGTGGGACGTCCTCATCGCCGATTCGGCGAAGGGT
TTTTGGTCAACGAACGCGCCGCTCATCATCCGCAATCACGTGATCGTGGGCGTCGCGGGCGATTTCGACAATCTCCCCGG
CACCCTGCGGTCCTTCGACGCCGACACCGGCAAACCGCAGTGGACGTTCTACAGCACGCCGCCTCCAAGCGCGGGCGATA
CCAGCAGCGGCGGCGCGACCGGTGGACAAATGTGGAATACCGGCACCTATGATCCGGATTTGAACTTGATGTTCGTCGGT
ACCGGCAATCCAACGCCGGTGCTGAACGGGAGCGTACGCCCGGGTGATAATCCCTGGACCTGCAGCATTGTCGCGCTGAA
CCCGGACACCGGCAAATTAGCCTGGGGATTCCAAGTCTCTCCCCACGACACGCATGACTGGGATGCCGCCGAAGTTCCGG
TGCTGGTCGATGGCAACTTCGACGGCCAGCCCCGAAAGATGTTGCTCCAGGCATCGCGCAATGGCTACTTCTTTGTGATC
GACCGGACCAATGGTAAAAGCCTGCTTACCAAGCCTTTCGCCGCAGTCAACTGGAGTAAGGGCATCGACGAGCAGGGTCG
TCCCATTCCGAATCCCGCCAAGGAGCCGCGCAAGGACGGCGCTCTAATCGCGCCGGATGAGGGTGGCGCAACGAACTTCT
GGCCGCCGAGCTTTGACCCTAAGACTGGGTTGCTGATCGTCAACGCCAAGGACGGATACGGCATTTACTTCTACAAACCC
GAGCATGGCGCGTACGGCTGGGCCGGGGCGGATTACGGACTCGCGGGCAAGGGCTTCCTCCGCGCCATCGACTACAAGAC
AGGGAAGATCGTCTGGGAACACCCGTACCCTCGCGGCAGCTCCTCGGCGGGTGTCCTCACGACTTCTACGGACCTGGCAA
TTACCGGCGACGCGGGCGGCAACCTGCTGGCTGTTCGATCGAGCGACGGCAAGGTCGTGTGGCACGAGAACATCGGCCGG
ATGGGCGGCGCTCCGGTGACGGTCGAACTCGACGGCAAACAGTACCTGCTCGTGACGGGCGGCAACTCGCTCTTCGCATA
CGCGCTTCCGTAG

Upstream 100 bases:

>100_bases
AGGTCGATGACGCGCTCGCGGCCCATTTCGATCAGCTCGGAAGATACACGGACGCCGACATGCACAATGTCTACGCCTAC
CTGGAGACTTTGAAATAGAC

Downstream 100 bases:

>100_bases
CCGCGGAGCGTTGTCCGCTTAAAGCCCTATCACGGCGTCATGGTCACGCCTGCGAACCTGATCCTGCAACGCAAGCGCCG
TGAGTGCGCCGCCGGTAGCG

Product: pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QH-EDH1; Quinohaemoprotein ethanol dehydrogenase type I [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MRLETRIATLLCAAALPIGAQSVDPKLLLSPPTNAWLTYHGDYTGERHSKLSEITPENISKLKQVWKFQSSQQLKASPIV
ANGMIYITAPDNLWAIDAHSGKEVWHHQHTKNNAFHIGHRGAAIYKDTVYLTTPDCHLLALNSRNGEVKWDVLIADSAKG
FWSTNAPLIIRNHVIVGVAGDFDNLPGTLRSFDADTGKPQWTFYSTPPPSAGDTSSGGATGGQMWNTGTYDPDLNLMFVG
TGNPTPVLNGSVRPGDNPWTCSIVALNPDTGKLAWGFQVSPHDTHDWDAAEVPVLVDGNFDGQPRKMLLQASRNGYFFVI
DRTNGKSLLTKPFAAVNWSKGIDEQGRPIPNPAKEPRKDGALIAPDEGGATNFWPPSFDPKTGLLIVNAKDGYGIYFYKP
EHGAYGWAGADYGLAGKGFLRAIDYKTGKIVWEHPYPRGSSSAGVLTTSTDLAITGDAGGNLLAVRSSDGKVVWHENIGR
MGGAPVTVELDGKQYLLVTGGNSLFAYALP

Sequences:

>Translated_510_residues
MRLETRIATLLCAAALPIGAQSVDPKLLLSPPTNAWLTYHGDYTGERHSKLSEITPENISKLKQVWKFQSSQQLKASPIV
ANGMIYITAPDNLWAIDAHSGKEVWHHQHTKNNAFHIGHRGAAIYKDTVYLTTPDCHLLALNSRNGEVKWDVLIADSAKG
FWSTNAPLIIRNHVIVGVAGDFDNLPGTLRSFDADTGKPQWTFYSTPPPSAGDTSSGGATGGQMWNTGTYDPDLNLMFVG
TGNPTPVLNGSVRPGDNPWTCSIVALNPDTGKLAWGFQVSPHDTHDWDAAEVPVLVDGNFDGQPRKMLLQASRNGYFFVI
DRTNGKSLLTKPFAAVNWSKGIDEQGRPIPNPAKEPRKDGALIAPDEGGATNFWPPSFDPKTGLLIVNAKDGYGIYFYKP
EHGAYGWAGADYGLAGKGFLRAIDYKTGKIVWEHPYPRGSSSAGVLTTSTDLAITGDAGGNLLAVRSSDGKVVWHENIGR
MGGAPVTVELDGKQYLLVTGGNSLFAYALP
>Mature_510_residues
MRLETRIATLLCAAALPIGAQSVDPKLLLSPPTNAWLTYHGDYTGERHSKLSEITPENISKLKQVWKFQSSQQLKASPIV
ANGMIYITAPDNLWAIDAHSGKEVWHHQHTKNNAFHIGHRGAAIYKDTVYLTTPDCHLLALNSRNGEVKWDVLIADSAKG
FWSTNAPLIIRNHVIVGVAGDFDNLPGTLRSFDADTGKPQWTFYSTPPPSAGDTSSGGATGGQMWNTGTYDPDLNLMFVG
TGNPTPVLNGSVRPGDNPWTCSIVALNPDTGKLAWGFQVSPHDTHDWDAAEVPVLVDGNFDGQPRKMLLQASRNGYFFVI
DRTNGKSLLTKPFAAVNWSKGIDEQGRPIPNPAKEPRKDGALIAPDEGGATNFWPPSFDPKTGLLIVNAKDGYGIYFYKP
EHGAYGWAGADYGLAGKGFLRAIDYKTGKIVWEHPYPRGSSSAGVLTTSTDLAITGDAGGNLLAVRSSDGKVVWHENIGR
MGGAPVTVELDGKQYLLVTGGNSLFAYALP

Specific function: Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=625, Percent_Identity=24.96, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.98.1 [H]

Molecular weight: Translated: 55090; Mature: 55090

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00364 BACTERIAL_PQQ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLETRIATLLCAAALPIGAQSVDPKLLLSPPTNAWLTYHGDYTGERHSKLSEITPENIS
CCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHCCHHHHH
KLKQVWKFQSSQQLKASPIVANGMIYITAPDNLWAIDAHSGKEVWHHQHTKNNAFHIGHR
HHHHHHHCCCCCCCCCCCEEECCEEEEECCCCEEEEECCCCHHHHHHCCCCCCEEEEECC
GAAIYKDTVYLTTPDCHLLALNSRNGEVKWDVLIADSAKGFWSTNAPLIIRNHVIVGVAG
CCEEEEEEEEEECCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCEEEECEEEEEEEC
DFDNLPGTLRSFDADTGKPQWTFYSTPPPSAGDTSSGGATGGQMWNTGTYDPDLNLMFVG
CCCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
TGNPTPVLNGSVRPGDNPWTCSIVALNPDTGKLAWGFQVSPHDTHDWDAAEVPVLVDGNF
CCCCCCEEECCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCC
DGQPRKMLLQASRNGYFFVIDRTNGKSLLTKPFAAVNWSKGIDEQGRPIPNPAKEPRKDG
CCCCHHEEEEECCCCEEEEEECCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCC
ALIAPDEGGATNFWPPSFDPKTGLLIVNAKDGYGIYFYKPEHGAYGWAGADYGLAGKGFL
CEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEE
RAIDYKTGKIVWEHPYPRGSSSAGVLTTSTDLAITGDAGGNLLAVRSSDGKVVWHENIGR
EEEECCCCEEEEECCCCCCCCCCCEEEECCCEEEECCCCCCEEEEECCCCCEEECCCCCC
MGGAPVTVELDGKQYLLVTGGNSLFAYALP
CCCCCEEEEECCCEEEEEECCCEEEEEECC
>Mature Secondary Structure
MRLETRIATLLCAAALPIGAQSVDPKLLLSPPTNAWLTYHGDYTGERHSKLSEITPENIS
CCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEECCCCCHHHHHHHHCCHHHHH
KLKQVWKFQSSQQLKASPIVANGMIYITAPDNLWAIDAHSGKEVWHHQHTKNNAFHIGHR
HHHHHHHCCCCCCCCCCCEEECCEEEEECCCCEEEEECCCCHHHHHHCCCCCCEEEEECC
GAAIYKDTVYLTTPDCHLLALNSRNGEVKWDVLIADSAKGFWSTNAPLIIRNHVIVGVAG
CCEEEEEEEEEECCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCEEEECEEEEEEEC
DFDNLPGTLRSFDADTGKPQWTFYSTPPPSAGDTSSGGATGGQMWNTGTYDPDLNLMFVG
CCCCCCCHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
TGNPTPVLNGSVRPGDNPWTCSIVALNPDTGKLAWGFQVSPHDTHDWDAAEVPVLVDGNF
CCCCCCEEECCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCC
DGQPRKMLLQASRNGYFFVIDRTNGKSLLTKPFAAVNWSKGIDEQGRPIPNPAKEPRKDG
CCCCHHEEEEECCCCEEEEEECCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCC
ALIAPDEGGATNFWPPSFDPKTGLLIVNAKDGYGIYFYKPEHGAYGWAGADYGLAGKGFL
CEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCEE
RAIDYKTGKIVWEHPYPRGSSSAGVLTTSTDLAITGDAGGNLLAVRSSDGKVVWHENIGR
EEEECCCCEEEEECCCCCCCCCCCEEEECCCEEEECCCCCCEEEEECCCCCEEECCCCCC
MGGAPVTVELDGKQYLLVTGGNSLFAYALP
CCCCCEEEEECCCEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654419; 7601151; 3521592; 11679760; 11714714 [H]