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The map label for this gene is aes [C]

Identifier: 116621207

GI number: 116621207

Start: 2658344

End: 2659252

Strand: Reverse

Name: aes [C]

Synonym: Acid_2088

Alternate gene names: 116621207

Gene position: 2659252-2658344 (Counterclockwise)

Preceding gene: 116621208

Following gene: 116621204

Centisome position: 26.68

GC content: 60.84

Gene sequence:

>909_bases
ATGAGCGGAAGAATGTTATTGCGGCTGTCTCTGGCCGGATTGATCGTACTGACGCCGCTCTGTGGGGCTGACCAGGGATC
GCCGGCGGCGACTTGGGCGGCGCGTGCCGTCAGTCAGTACATCTCCCTGCCGGATATCACGTATTTTTCGGCCGGCAATT
TGGAGCTGAAGCTCGATGTCCATCGCCGCCGGGGCCTGACCGGGCCACAGCCGGCCGTAATCTATATCCACGGCGGAGGC
TGGATCGGCGGCTCGAAAGGAGGCGCGCTCAGTCTGCTGTTGCCCTGGTTCGAGATGGGCTTCACCATCATCAACGTGGA
ATACCGCCTGTTACGGGCCGCCCCTGCGCCGGCGGCCGTTATCGACTGCCTCTGCGCACTGCGTTTTGTGGCAGGCCGCG
CCCAAAACTATGGCATCGATACCACGCGTCTGGTGATCAGCGGAGAATCGGCGGGCGGACACCTGGCGCTCACCACCGCC
ATGATTCCGGAGAGCGCGGAAATGGATAAACAGTGTCCCGGGGCGCCGCTACCGAAAATCGCGGCAGTCGTGAACTTTTA
TGGGATTACCGATGTAGCGGACCTGCTGGAAGGCCCGAATCAGAAGAGCTACGCGGTATCCTGGATCGGCAACGGAGCGG
ACCGGCAGGAACTCGCGAAACGTTTGTCGCCGCTAACGTATGTGCGACCCGGTCTGCCACCGATACTCACGATTCAGGGC
GATGCCGATCCGATCGTGCCGTACTCCCATTCCGTGCGGCTCCAGGAAGCGCTCGAGAAGGTCAATGTGCCGCATCAACT
CGTCACCATACAGGGCGGCAAGCACGGTATGTTCACGGGAGACGAATACGTCCGGATCTACTCCGAGATTCGGACGTTCC
TGACGAAATACAACCTGCTGCCGAAGTGA

Upstream 100 bases:

>100_bases
TGCGGCGGATGGGCTGCATCCCAACGCCGAGGGCTACAAGATCATGTCGCCAATTGTCTCGGCGGCGATAGATCAGGCGT
TGCGCTAACAGGGAAGAACG

Downstream 100 bases:

>100_bases
GCGGATCGAGTTACGCGTCGTAACCCGTCAGGCGCCGCACCCAGATATTGCGATACCAGGCGGGCCCGACATGTCCCTGC
AAGCCTAGCGGGAGTTCGGG

Product: alpha/beta hydrolase domain-containing protein

Products: alcohol; a carboxylate [C]

Alternate protein names: Alpha/Beta Hydrolase Fold-3 Domain Protein; Lipase/Esterase; Alpha/Beta Hydrolase Domain-Containing Protein; Esterase; Esterase/Lipase-Like Protein; Esterase/Lipase; Esterase/Lipase/Thioesterase; Alpha/Beta Hydrolase; Alpha/Beta Hydrolase Fold Protein-3 Domain Protein; Lipase Esterase; Dienelactone Hydrolase; Dipeptidyl Aminopeptidases/Acylaminoacyl-Peptidases-Like; Alpha/Beta Hydrolase Fold-3 Domain-Containing Protein; Peptidase S; Lipoprotein

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSGRMLLRLSLAGLIVLTPLCGADQGSPAATWAARAVSQYISLPDITYFSAGNLELKLDVHRRRGLTGPQPAVIYIHGGG
WIGGSKGGALSLLLPWFEMGFTIINVEYRLLRAAPAPAAVIDCLCALRFVAGRAQNYGIDTTRLVISGESAGGHLALTTA
MIPESAEMDKQCPGAPLPKIAAVVNFYGITDVADLLEGPNQKSYAVSWIGNGADRQELAKRLSPLTYVRPGLPPILTIQG
DADPIVPYSHSVRLQEALEKVNVPHQLVTIQGGKHGMFTGDEYVRIYSEIRTFLTKYNLLPK

Sequences:

>Translated_302_residues
MSGRMLLRLSLAGLIVLTPLCGADQGSPAATWAARAVSQYISLPDITYFSAGNLELKLDVHRRRGLTGPQPAVIYIHGGG
WIGGSKGGALSLLLPWFEMGFTIINVEYRLLRAAPAPAAVIDCLCALRFVAGRAQNYGIDTTRLVISGESAGGHLALTTA
MIPESAEMDKQCPGAPLPKIAAVVNFYGITDVADLLEGPNQKSYAVSWIGNGADRQELAKRLSPLTYVRPGLPPILTIQG
DADPIVPYSHSVRLQEALEKVNVPHQLVTIQGGKHGMFTGDEYVRIYSEIRTFLTKYNLLPK
>Mature_301_residues
SGRMLLRLSLAGLIVLTPLCGADQGSPAATWAARAVSQYISLPDITYFSAGNLELKLDVHRRRGLTGPQPAVIYIHGGGW
IGGSKGGALSLLLPWFEMGFTIINVEYRLLRAAPAPAAVIDCLCALRFVAGRAQNYGIDTTRLVISGESAGGHLALTTAM
IPESAEMDKQCPGAPLPKIAAVVNFYGITDVADLLEGPNQKSYAVSWIGNGADRQELAKRLSPLTYVRPGLPPILTIQGD
ADPIVPYSHSVRLQEALEKVNVPHQLVTIQGGKHGMFTGDEYVRIYSEIRTFLTKYNLLPK

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI71996133, Length=132, Percent_Identity=36.3636363636364, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17540028, Length=131, Percent_Identity=32.824427480916, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 32520; Mature: 32389

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRMLLRLSLAGLIVLTPLCGADQGSPAATWAARAVSQYISLPDITYFSAGNLELKLDV
CCCCEEEEEHHCCHHEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEE
HRRRGLTGPQPAVIYIHGGGWIGGSKGGALSLLLPWFEMGFTIINVEYRLLRAAPAPAAV
HHHCCCCCCCCEEEEEECCEEECCCCCCEEEEEHHHHHCCEEEEEEEEEEEECCCCHHHH
IDCLCALRFVAGRAQNYGIDTTRLVISGESAGGHLALTTAMIPESAEMDKQCPGAPLPKI
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHCCCCCCCHHH
AAVVNFYGITDVADLLEGPNQKSYAVSWIGNGADRQELAKRLSPLTYVRPGLPPILTIQG
HHHHHHHCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHCCCCEEECCCCCEEEEEEC
DADPIVPYSHSVRLQEALEKVNVPHQLVTIQGGKHGMFTGDEYVRIYSEIRTFLTKYNLL
CCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PK
CC
>Mature Secondary Structure 
SGRMLLRLSLAGLIVLTPLCGADQGSPAATWAARAVSQYISLPDITYFSAGNLELKLDV
CCCEEEEEHHCCHHEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEE
HRRRGLTGPQPAVIYIHGGGWIGGSKGGALSLLLPWFEMGFTIINVEYRLLRAAPAPAAV
HHHCCCCCCCCEEEEEECCEEECCCCCCEEEEEHHHHHCCEEEEEEEEEEEECCCCHHHH
IDCLCALRFVAGRAQNYGIDTTRLVISGESAGGHLALTTAMIPESAEMDKQCPGAPLPKI
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCHHHCCCCCCCHHH
AAVVNFYGITDVADLLEGPNQKSYAVSWIGNGADRQELAKRLSPLTYVRPGLPPILTIQG
HHHHHHHCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHCCCCEEECCCCCEEEEEEC
DADPIVPYSHSVRLQEALEKVNVPHQLVTIQGGKHGMFTGDEYVRIYSEIRTFLTKYNLL
CCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA