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The map label for this gene is yajO [H]

Identifier: 116621117

GI number: 116621117

Start: 2526931

End: 2527911

Strand: Direct

Name: yajO [H]

Synonym: Acid_1998

Alternate gene names: 116621117

Gene position: 2526931-2527911 (Clockwise)

Preceding gene: 116621116

Following gene: 116621118

Centisome position: 25.36

GC content: 60.86

Gene sequence:

>981_bases
ATGGAATATGTGCGCCTCGGTTCTACCGGCCTCAAAGTTTCCCGCCTCTGTCTCGGCTGCATGACCTATGGATCGAAGAA
ATGGCGCGATTGGATCCTTGACGACGAAGAAAGCCGCCCCTTCTTCCGCCGCGCCCTCGAACTGGGAATCAACTTCTTCG
ACACAGCCGACATGTACTCCGTCGGAGTTAGCGAAGAGGTCACCGGCCGGGCCCTCAAGGATTTCGCGCAGCGCGACAAA
GTCGTCATCGCCACCAAAGTCTTCAACCCCATGGGCGACGACCCCAACCAGAAGGGACTTTCACGCAAGCACATCCACCA
CGCCATCGACGACAGCCTGCGCCGTCTCGGCACCGACTATATCGACCTCTACCAGGTCCATCGCTTCGATTACGAGACGC
CAATCGAAGAAACCCTGCGCGCGCTCGATGATGTGGTCCGCGCCGGTAAGGCGCTGTATATCGGCGCCTCCAGCATGTTC
GCGTACCAGTTCGCCAAAATGCTGAAGACGTCCGACGCCTTGGGACTGGCACGTTTCGTCAGCATGCAGAATCACTACAA
CCTGGTCTACCGCGAAGAGGAGCGCGAGGTGTTGCCGTTGTGCCGTGAGGAAGGCATCGGCGTGATTCCGTGGAGTCCGC
TGGCGCGCGGTTTCGTGGCCGGCAACCGCCGCGCCCAGGATTTCGGCGATACCGTGCGCGCCAGGACCGACGACTACGCG
AAGGATCTCTATTACCAGCCTTCGGATTTCACCGTGGTCGAGCGCGTAACCGAGATCGCGCAGCGCCGCGGAGTTCCGAA
CGCACAGGTGGCGCTCGCCTGGGTCTTACAGCAACCCGGCATTACCGCGCCCATCATCGGAGCCACCAAAATGCGGCACC
TGGATGACGCCGTCGCTGCGCTCGGCCTTAAACTTGATGAGGCGGAACTCAAGACGCTCTCCGAGCCCTACCAGCCGCAC
CCCATCCTTGGACACTCGTGA

Upstream 100 bases:

>100_bases
ACGGTAGATCGCCCGACCGCCTCCCGCGCGGTTTACACACTGGAGTGACCCGCCGCTTGATACTTACGTAAACCGCTAGC
TACCGTGGTATCCATGGAGA

Downstream 100 bases:

>100_bases
GCCCGATGCTGCGCACCGTTCAGGCCACCCGCTACGTGACTCCGTTCCGCGAAGGCGGATCGCTGCCCGCGCTCGTCGAA
GGCGACGATCTCGGTCTCTA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MEYVRLGSTGLKVSRLCLGCMTYGSKKWRDWILDDEESRPFFRRALELGINFFDTADMYSVGVSEEVTGRALKDFAQRDK
VVIATKVFNPMGDDPNQKGLSRKHIHHAIDDSLRRLGTDYIDLYQVHRFDYETPIEETLRALDDVVRAGKALYIGASSMF
AYQFAKMLKTSDALGLARFVSMQNHYNLVYREEEREVLPLCREEGIGVIPWSPLARGFVAGNRRAQDFGDTVRARTDDYA
KDLYYQPSDFTVVERVTEIAQRRGVPNAQVALAWVLQQPGITAPIIGATKMRHLDDAVAALGLKLDEAELKTLSEPYQPH
PILGHS

Sequences:

>Translated_326_residues
MEYVRLGSTGLKVSRLCLGCMTYGSKKWRDWILDDEESRPFFRRALELGINFFDTADMYSVGVSEEVTGRALKDFAQRDK
VVIATKVFNPMGDDPNQKGLSRKHIHHAIDDSLRRLGTDYIDLYQVHRFDYETPIEETLRALDDVVRAGKALYIGASSMF
AYQFAKMLKTSDALGLARFVSMQNHYNLVYREEEREVLPLCREEGIGVIPWSPLARGFVAGNRRAQDFGDTVRARTDDYA
KDLYYQPSDFTVVERVTEIAQRRGVPNAQVALAWVLQQPGITAPIIGATKMRHLDDAVAALGLKLDEAELKTLSEPYQPH
PILGHS
>Mature_326_residues
MEYVRLGSTGLKVSRLCLGCMTYGSKKWRDWILDDEESRPFFRRALELGINFFDTADMYSVGVSEEVTGRALKDFAQRDK
VVIATKVFNPMGDDPNQKGLSRKHIHHAIDDSLRRLGTDYIDLYQVHRFDYETPIEETLRALDDVVRAGKALYIGASSMF
AYQFAKMLKTSDALGLARFVSMQNHYNLVYREEEREVLPLCREEGIGVIPWSPLARGFVAGNRRAQDFGDTVRARTDDYA
KDLYYQPSDFTVVERVTEIAQRRGVPNAQVALAWVLQQPGITAPIIGATKMRHLDDAVAALGLKLDEAELKTLSEPYQPH
PILGHS

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=311, Percent_Identity=32.7974276527331, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=32.6860841423948, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI27436964, Length=314, Percent_Identity=31.5286624203822, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI27436962, Length=314, Percent_Identity=31.5286624203822, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI27436971, Length=309, Percent_Identity=33.0097087378641, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI27436966, Length=314, Percent_Identity=31.2101910828025, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI41152114, Length=301, Percent_Identity=27.906976744186, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223718702, Length=299, Percent_Identity=26.7558528428094, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI41327764, Length=273, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=55.6231003039514, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1789375, Length=316, Percent_Identity=33.5443037974684, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1789199, Length=358, Percent_Identity=32.6815642458101, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788070, Length=328, Percent_Identity=31.0975609756098, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788081, Length=280, Percent_Identity=32.5, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787674, Length=309, Percent_Identity=27.1844660194175, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325169, Length=339, Percent_Identity=40.7079646017699, Blast_Score=263, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6323998, Length=320, Percent_Identity=27.5, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6319958, Length=292, Percent_Identity=27.0547945205479, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319951, Length=319, Percent_Identity=26.6457680250784, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6322615, Length=248, Percent_Identity=27.0161290322581, Blast_Score=108, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6321052, Length=153, Percent_Identity=33.9869281045752, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640980, Length=329, Percent_Identity=24.9240121580547, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45549126, Length=329, Percent_Identity=24.9240121580547, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24646155, Length=304, Percent_Identity=29.9342105263158, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646159, Length=293, Percent_Identity=32.0819112627986, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36909; Mature: 36909

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYVRLGSTGLKVSRLCLGCMTYGSKKWRDWILDDEESRPFFRRALELGINFFDTADMYS
CCEEEECCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
VGVSEEVTGRALKDFAQRDKVVIATKVFNPMGDDPNQKGLSRKHIHHAIDDSLRRLGTDY
CCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
IDLYQVHRFDYETPIEETLRALDDVVRAGKALYIGASSMFAYQFAKMLKTSDALGLARFV
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHH
SMQNHYNLVYREEEREVLPLCREEGIGVIPWSPLARGFVAGNRRAQDFGDTVRARTDDYA
HHHCCCCEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHH
KDLYYQPSDFTVVERVTEIAQRRGVPNAQVALAWVLQQPGITAPIIGATKMRHLDDAVAA
HHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LGLKLDEAELKTLSEPYQPHPILGHS
HCCCCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEYVRLGSTGLKVSRLCLGCMTYGSKKWRDWILDDEESRPFFRRALELGINFFDTADMYS
CCEEEECCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHH
VGVSEEVTGRALKDFAQRDKVVIATKVFNPMGDDPNQKGLSRKHIHHAIDDSLRRLGTDY
CCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
IDLYQVHRFDYETPIEETLRALDDVVRAGKALYIGASSMFAYQFAKMLKTSDALGLARFV
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHH
SMQNHYNLVYREEEREVLPLCREEGIGVIPWSPLARGFVAGNRRAQDFGDTVRARTDDYA
HHHCCCCEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHH
KDLYYQPSDFTVVERVTEIAQRRGVPNAQVALAWVLQQPGITAPIIGATKMRHLDDAVAA
HHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
LGLKLDEAELKTLSEPYQPHPILGHS
HCCCCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]