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The map label for this gene is pksN [H]

Identifier: 116621092

GI number: 116621092

Start: 2489363

End: 2494303

Strand: Direct

Name: pksN [H]

Synonym: Acid_1973

Alternate gene names: 116621092

Gene position: 2489363-2494303 (Clockwise)

Preceding gene: 116621091

Following gene: 116621093

Centisome position: 24.98

GC content: 62.38

Gene sequence:

>4941_bases
ATGACCCCGCTCGATTCTCAACCCGATCCGCAGCCCGAACCAAGCCCGGTGCGCGGTGATATCGCCATCGTCGGCATGAG
CTGTCTCTTCGCCGGCGCTCCCGATCTCGACACCTACTGGCGAAACATCATCTCCAAAGTCGATTCCGTTTCCGATCCGC
CGGCCGGCGAATGGGATCCCAAGATATTTTACGATCCGGAGTCCAAATCCAACGATCGGGTGTACTGCAAGCGGGGCGGG
TACATCGGCGATATCGCGAGTTTTCGCCCGCTCGAGTTTGGCGTTATGCCCGTCACAGTGGACGGCGGCGAACCGGATCA
GTGGTTGGCCTTGCGTGTCGCCTCGGAGGCGCTCGCCGATGGCGGATATACGGAGCTGCCGAAGGAACACTTGCGAACCG
AAGTGGTCCTCGGAAAAGGCACCTACGTCAATCGCGGCAACCTCACTGTTGGGTATCACGGAATGATCGTGGAGCATTTC
CTCCGGGCGCTGAAGAATCTGCATCCCGAGTACACCGAGTCGGAGATCCACGCCATCAAGAAGGAGCTGAAGGCCGGCTT
ACCCCCGTTCAGCGCGGACACGGCCCCGGCGCTGATCGGCAATATTATCGCGGGTCGCATCGCGAACCGCCTGGATCTGA
TGGGGCCCAGTTTCACCGTGGACGCGGCATGCGCATCCGCGCTGCTGGCCATCGAGATCGGGGTTCGCGACCTCTTGAGC
CACAAGTACGACCTCGTGCTGGCGGGCGGCGCCAACGTGAATGCGCCGCTGCCCACGTTGAGTCTCTTCTGCCAGTTGGG
TGCTCTTTCGCGCGGCGAGCAAATCCGGCCGTTCGACAAACAGGCCGACGGCACCATCCTCGGCGAAGGTCTCGGGATGA
TTGTCCTGAAGCGGCGAAAAGACGCCGAGCGCGATGGGAATCGCATCTATGCCGTAATCAAGGGTGTCGGCGTCGCGAGT
GACGGACGCGCCGTTCACGTAATGGCGCCCCGCGTGGAGGGCGAAGAGCTGGCGCTGCGACGCGCGTACGAAATGGCAGG
GGTTGCCCAGCGGACGGTGGGCTTGATCGAAGCTCACGGCACCGCCACACCGGTTGGCGACGTGGTCGAAGTTCAGGCGC
TCGGCCGGGTCTTCGGCGAACGCGAGGGTTCGCTCCCCACCTGCGCGATTGGCTCGGTGAAGTCCATGATCGGCCACACC
ATGCCGGCCGCCGGAATCGCCGGCGTGATCAAAACCGCGCTGGCCCTGTATCACCGTGTACTGCCGCCCACCCTTCACTG
CCAAGAACCAAATCCCGCGCTCCACCTGGAGCGAACGCCTTTCTACGTGAATACGGAGACGCGCCCGTGGATTCACGGAG
CGGAGACGCCGCGGCGTGCTGGAGTTAATTCCTTTGGCTTCGGCGGCATTAATGCACATGTCGTGCTTGAAGAGCACCCC
GCCGAATTGCCGGAAGCGCGCAACTGCCAGATTCACTGGGAAACGGAAGTCTGCATTATTGAAGCGGAATCCCGCAGCGG
ATTGATCGACCGCGCGGCCCGGCTGAAGGAGTATTTATCGCAGCCGGCGGTCACGCTCAAGGACCTGGCTTATAGTCTCA
ATACCCGGTTGGAAGGCAAGCCCAGCCGGCTGGCGGTGATCGCTTCCTCCACGGATGACCTGGCTCAAAAACTAACGCTC
GCGATCGCGCGCCTCGGCGACCCGCAGTGCTCGCAGATCAAGGACAACGGCGGGACTTACTTCTTCGACAAGCCGCTCGA
GGGCAAACTCGCATTTCTTTTTCCGGGTGAAGGCGCGCAGTACCCGAATTTGCTGCATGACCTCTGTCTTCACTTCCCGG
AGGTGCGGCAGTGCTTTGACATTGCGGATCGCGCCACGCTGCGTGGTAACGCAACCATCCTGCCCAGCGAGTTCATGTTC
CCGCGGTCCATTCTCTCGGACACGGAACGTTCCGAAGTGGAGCGGGCGCTGTGGAGTCTCGACGGCGCTGTGGCGGCTGT
CCTTATCGGCAATTGGGCGATGTGGACGCTGCTGAGGTGTCTGCAGATTCGACCCGATTCGATCGCGGGCCACAGCACCG
GCGACTATTCGGCGATGTTTGCGTCAAGTACGGTCGAAATAGCCCGCGAAGCGGAAGTGGAGACCATTCTCGAGTGGAGC
AAAGCTCACAGCGAGCTGGTCGAGCGGGTTGCGGTACCGGGTGCGACCTTGATCGCAGTGGCGGCCGATTCGGCCACAGT
CCGCTCGATCATCGAAAGCATTGGCGGCGATCTTTACCTCGCTATGGACAACTGTCCGCACCAGAGCGTTTTGGTCGGCG
GTAAGATTTCCGCCGCGCAGGCCATCGAACAGTTGCGCAAACAGGGAATCATTTACGAGATCCTCCCCTTTGACCGTCCG
TATCACACGCCGATGTTCCAGCCCTATGCCGAAGGAACGGCAGAAGCGTTCTTCGCGCGGGTTCGAGTCAATGCCCCCGC
AATTGAAACCTACTCCTGCACTACGGCTTCGCGCTATCCAGCGGACGCCGAAGAAATCCGCAGACTGTTTGTAGACCACT
GGGTGGGCCCGGTGCGCTTCACCGAGACCATTAATAGGATGTACGAGGACGGGGTGCGCCTCTTTGTCGAGGCGGGCCCG
CGCGGGAATTTAACCGCATTCGTCAGCGACATTTTGCGCGGCCGTCCACACCTTGCCATGCCGGCCAACGTCGCCCGGCG
GTCGGGACTGACCCAGATCAATCACCTCGCCGGCGTACTGGCCGCGCAAGGTGTCGGAATGCGCCTCGAGTATCTGTATG
CCCGGCGCGATCCTCAATTCATTCCGTGGGAGAGCGCGAGACCCTCCACTCCCGCGAAGGTGCGGCCCGCGGCAATGAAG
CTCACCCTCGCACTGCCGCCGTTGACGGTCTCGCCCCGCGCACCGAAAGCCGAAGGCGCCGTTGCGACGGCGCGAAACGG
CAGTGAAACCCCGGTACCGCATCGGGTTGCGCCCGAGATTACACGGCCGCAAGCATCGCCGAGTAACGGCGCACCGGCGG
CCGTAGCGGTCGCCCCGGCGTCCATTCACGCACTCCACTCCAAGGCTTCATCCGCGGCCGTGATGCAGGAGTACTTCAAA
GGCATGGAGAATTTCCTGGAGGTCGAGACAGAGGTGATGGGCGCATTCCTCAAGCGCCGGCCCGCGACTCAAGCCGCAAG
CAGCGGTACGGCATCCGCCCCGATTCCCGCTGAGTTTCCGCTGCTCGGGACCATCACCGCGCTCGTGCCGGGCGAGGAAT
TGACAGCCCTACGCCAACTCAGCCAGCAGGAGGATCTCTTCCTGCGCGACCACGCCTTGGGTGGGCGGGTGTCCCTGACG
GATCCGGATCTGAGGCCGCTGATCGTTCTACCCCTGACCATGAGTATGGAAATCCTCGCCGAGGCCGGGGCCGCCTTGAT
GCGGCGCCAGGTGCTCGTGGGAATGCGCAATGTCCAGGCACATCACTGGATTCAGGTCGATGACGCTCCGGTAAGTTTAC
AGATCTCCGCAAACCGGCTGGCTAACTCGCAGAACGAAGTAACGGTTCAGGTCCGGAACACGAAAGCCGGTCCGGCGCCG
GTAATTGAAGGGATCATGATCTTCGCCGACGACTATCCCACCTCGCCGCCCTCATCCGCTCTTCCTCTGGCCGCCGAGCG
CCGGTCGCAACTCGCATCCACCGATCTCTACAACGGTCGCCTGATGTTTCACGGCCCCGCCTTCCAAGGGGTTGTCAGCG
TGGAACGGTCGGGTCAGAACGGCATGACCGGGCAGCTTCGCACACTGCCCACCCGACATCTATTCCGTTCGATTCCGAAT
CCGCTGTTCGTCACCGACCCCGTGGTACTGGATGCCGCCGGACAGCTCGTCGGGTTTTGGGCGGCCGAATACCTGAGCCG
CGGCTTCGTCGTCTTCCCTTATCACCTCGATCGTCTGACTATCTATGGACCCAACCCGCGAGCCGGGCAAAGCCTGACGT
GCCGCCTCTCCGTACAATCCACAGCGAAGGAAAGCATGCGTTCCGATATTGAAGTCGCCGGGGCGGATGGCGCGGTCTGG
ATGCATCTTCAAGGCTGGGCCGACCGCCGGTTCGATCCGCCGGAGCGCTTTCACCGCGCCTGGATCGCCCCGGGCGAGGC
CATGATCAGCGAGCCTTGGCCGGCATCTCTCAAGAGCCTGCCAGATGGTGAGTCCCTTGAGTGCCGCCGTGTGAACCTGC
TTTTCGAGGAGAGCGGCAGCCTCTGGAAGGACCTATGGGCGTCCCTGGTGCTCACTGCCCGGGAACGCGGCGAGTTCGCG
GAGCGTCGGGGTCCGGAGCGTCGTCAGCTGGAATGGCTGGCGGGCCGGACCGCTGCCAAGGACGCGGTACGCGGCTTCTT
ACAAAAGCATCACGCGATACAGCTCTTCCCGGCTGACATCGAGATCACCCACGACGAATACGGCAGACCCATTGCCCGTG
GACCGTGGACGCAAAGCCTTCATGCTTCCCCGCACGTGTCCATTTCGCATTCGCAAAACGTGGCCGTCGCATTGGCTTAC
GACGGGAGCCGGGGAATGGGTTACGGAATCGACCTGCAAGCCATCCGCGAACTCGCGCCGGATTTTGAAGCATCGGTCTT
GACTGGGGAGGAGCAGCGCCATTTGGAGGTTGTCCCAGCGAACTTGCGAGCGGAATGGATCCTCCGACTCTGGTGTGCGA
AGGAAGCCGTTTCGAAGGCGCTCGGCAGGGGCCTCATCGAAGGGCCCGCGAGCGTGCGGATCCTGGCTTTGGACGCGCGG
ACGGGCGACGTCGTTGCGACGCCGCACGGAAAACTGGCGGCGGGCGTGCCGGAAGCTGCCGGCCGGAAACTTTCAGCCTT
CACGATGCGTGAAGGTGCCTTTGTATTTGCGACCGCAATATTCGAGAAGAGAACATCATGA

Upstream 100 bases:

>100_bases
GCCGTGTCCTGAGCGTTCTCGAGGACATGCAAGGCACATGCAGTAAGTCTTTGAATCGCTTGGCTGGCCGGGAGATTGCG
CTGGCGGTCGGAAACGCGTC

Downstream 100 bases:

>100_bases
ACACAGTCAATCAAGAACACATATTGACGGACGTGCTCAACCTGCTCAAGGACCTGTCACGGGATTGGGAATACTCCGGG
GAGATTACGCCCGATACCTT

Product: beta-ketoacyl synthase

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1646; Mature: 1645

Protein sequence:

>1646_residues
MTPLDSQPDPQPEPSPVRGDIAIVGMSCLFAGAPDLDTYWRNIISKVDSVSDPPAGEWDPKIFYDPESKSNDRVYCKRGG
YIGDIASFRPLEFGVMPVTVDGGEPDQWLALRVASEALADGGYTELPKEHLRTEVVLGKGTYVNRGNLTVGYHGMIVEHF
LRALKNLHPEYTESEIHAIKKELKAGLPPFSADTAPALIGNIIAGRIANRLDLMGPSFTVDAACASALLAIEIGVRDLLS
HKYDLVLAGGANVNAPLPTLSLFCQLGALSRGEQIRPFDKQADGTILGEGLGMIVLKRRKDAERDGNRIYAVIKGVGVAS
DGRAVHVMAPRVEGEELALRRAYEMAGVAQRTVGLIEAHGTATPVGDVVEVQALGRVFGEREGSLPTCAIGSVKSMIGHT
MPAAGIAGVIKTALALYHRVLPPTLHCQEPNPALHLERTPFYVNTETRPWIHGAETPRRAGVNSFGFGGINAHVVLEEHP
AELPEARNCQIHWETEVCIIEAESRSGLIDRAARLKEYLSQPAVTLKDLAYSLNTRLEGKPSRLAVIASSTDDLAQKLTL
AIARLGDPQCSQIKDNGGTYFFDKPLEGKLAFLFPGEGAQYPNLLHDLCLHFPEVRQCFDIADRATLRGNATILPSEFMF
PRSILSDTERSEVERALWSLDGAVAAVLIGNWAMWTLLRCLQIRPDSIAGHSTGDYSAMFASSTVEIAREAEVETILEWS
KAHSELVERVAVPGATLIAVAADSATVRSIIESIGGDLYLAMDNCPHQSVLVGGKISAAQAIEQLRKQGIIYEILPFDRP
YHTPMFQPYAEGTAEAFFARVRVNAPAIETYSCTTASRYPADAEEIRRLFVDHWVGPVRFTETINRMYEDGVRLFVEAGP
RGNLTAFVSDILRGRPHLAMPANVARRSGLTQINHLAGVLAAQGVGMRLEYLYARRDPQFIPWESARPSTPAKVRPAAMK
LTLALPPLTVSPRAPKAEGAVATARNGSETPVPHRVAPEITRPQASPSNGAPAAVAVAPASIHALHSKASSAAVMQEYFK
GMENFLEVETEVMGAFLKRRPATQAASSGTASAPIPAEFPLLGTITALVPGEELTALRQLSQQEDLFLRDHALGGRVSLT
DPDLRPLIVLPLTMSMEILAEAGAALMRRQVLVGMRNVQAHHWIQVDDAPVSLQISANRLANSQNEVTVQVRNTKAGPAP
VIEGIMIFADDYPTSPPSSALPLAAERRSQLASTDLYNGRLMFHGPAFQGVVSVERSGQNGMTGQLRTLPTRHLFRSIPN
PLFVTDPVVLDAAGQLVGFWAAEYLSRGFVVFPYHLDRLTIYGPNPRAGQSLTCRLSVQSTAKESMRSDIEVAGADGAVW
MHLQGWADRRFDPPERFHRAWIAPGEAMISEPWPASLKSLPDGESLECRRVNLLFEESGSLWKDLWASLVLTARERGEFA
ERRGPERRQLEWLAGRTAAKDAVRGFLQKHHAIQLFPADIEITHDEYGRPIARGPWTQSLHASPHVSISHSQNVAVALAY
DGSRGMGYGIDLQAIRELAPDFEASVLTGEEQRHLEVVPANLRAEWILRLWCAKEAVSKALGRGLIEGPASVRILALDAR
TGDVVATPHGKLAAGVPEAAGRKLSAFTMREGAFVFATAIFEKRTS

Sequences:

>Translated_1646_residues
MTPLDSQPDPQPEPSPVRGDIAIVGMSCLFAGAPDLDTYWRNIISKVDSVSDPPAGEWDPKIFYDPESKSNDRVYCKRGG
YIGDIASFRPLEFGVMPVTVDGGEPDQWLALRVASEALADGGYTELPKEHLRTEVVLGKGTYVNRGNLTVGYHGMIVEHF
LRALKNLHPEYTESEIHAIKKELKAGLPPFSADTAPALIGNIIAGRIANRLDLMGPSFTVDAACASALLAIEIGVRDLLS
HKYDLVLAGGANVNAPLPTLSLFCQLGALSRGEQIRPFDKQADGTILGEGLGMIVLKRRKDAERDGNRIYAVIKGVGVAS
DGRAVHVMAPRVEGEELALRRAYEMAGVAQRTVGLIEAHGTATPVGDVVEVQALGRVFGEREGSLPTCAIGSVKSMIGHT
MPAAGIAGVIKTALALYHRVLPPTLHCQEPNPALHLERTPFYVNTETRPWIHGAETPRRAGVNSFGFGGINAHVVLEEHP
AELPEARNCQIHWETEVCIIEAESRSGLIDRAARLKEYLSQPAVTLKDLAYSLNTRLEGKPSRLAVIASSTDDLAQKLTL
AIARLGDPQCSQIKDNGGTYFFDKPLEGKLAFLFPGEGAQYPNLLHDLCLHFPEVRQCFDIADRATLRGNATILPSEFMF
PRSILSDTERSEVERALWSLDGAVAAVLIGNWAMWTLLRCLQIRPDSIAGHSTGDYSAMFASSTVEIAREAEVETILEWS
KAHSELVERVAVPGATLIAVAADSATVRSIIESIGGDLYLAMDNCPHQSVLVGGKISAAQAIEQLRKQGIIYEILPFDRP
YHTPMFQPYAEGTAEAFFARVRVNAPAIETYSCTTASRYPADAEEIRRLFVDHWVGPVRFTETINRMYEDGVRLFVEAGP
RGNLTAFVSDILRGRPHLAMPANVARRSGLTQINHLAGVLAAQGVGMRLEYLYARRDPQFIPWESARPSTPAKVRPAAMK
LTLALPPLTVSPRAPKAEGAVATARNGSETPVPHRVAPEITRPQASPSNGAPAAVAVAPASIHALHSKASSAAVMQEYFK
GMENFLEVETEVMGAFLKRRPATQAASSGTASAPIPAEFPLLGTITALVPGEELTALRQLSQQEDLFLRDHALGGRVSLT
DPDLRPLIVLPLTMSMEILAEAGAALMRRQVLVGMRNVQAHHWIQVDDAPVSLQISANRLANSQNEVTVQVRNTKAGPAP
VIEGIMIFADDYPTSPPSSALPLAAERRSQLASTDLYNGRLMFHGPAFQGVVSVERSGQNGMTGQLRTLPTRHLFRSIPN
PLFVTDPVVLDAAGQLVGFWAAEYLSRGFVVFPYHLDRLTIYGPNPRAGQSLTCRLSVQSTAKESMRSDIEVAGADGAVW
MHLQGWADRRFDPPERFHRAWIAPGEAMISEPWPASLKSLPDGESLECRRVNLLFEESGSLWKDLWASLVLTARERGEFA
ERRGPERRQLEWLAGRTAAKDAVRGFLQKHHAIQLFPADIEITHDEYGRPIARGPWTQSLHASPHVSISHSQNVAVALAY
DGSRGMGYGIDLQAIRELAPDFEASVLTGEEQRHLEVVPANLRAEWILRLWCAKEAVSKALGRGLIEGPASVRILALDAR
TGDVVATPHGKLAAGVPEAAGRKLSAFTMREGAFVFATAIFEKRTS
>Mature_1645_residues
TPLDSQPDPQPEPSPVRGDIAIVGMSCLFAGAPDLDTYWRNIISKVDSVSDPPAGEWDPKIFYDPESKSNDRVYCKRGGY
IGDIASFRPLEFGVMPVTVDGGEPDQWLALRVASEALADGGYTELPKEHLRTEVVLGKGTYVNRGNLTVGYHGMIVEHFL
RALKNLHPEYTESEIHAIKKELKAGLPPFSADTAPALIGNIIAGRIANRLDLMGPSFTVDAACASALLAIEIGVRDLLSH
KYDLVLAGGANVNAPLPTLSLFCQLGALSRGEQIRPFDKQADGTILGEGLGMIVLKRRKDAERDGNRIYAVIKGVGVASD
GRAVHVMAPRVEGEELALRRAYEMAGVAQRTVGLIEAHGTATPVGDVVEVQALGRVFGEREGSLPTCAIGSVKSMIGHTM
PAAGIAGVIKTALALYHRVLPPTLHCQEPNPALHLERTPFYVNTETRPWIHGAETPRRAGVNSFGFGGINAHVVLEEHPA
ELPEARNCQIHWETEVCIIEAESRSGLIDRAARLKEYLSQPAVTLKDLAYSLNTRLEGKPSRLAVIASSTDDLAQKLTLA
IARLGDPQCSQIKDNGGTYFFDKPLEGKLAFLFPGEGAQYPNLLHDLCLHFPEVRQCFDIADRATLRGNATILPSEFMFP
RSILSDTERSEVERALWSLDGAVAAVLIGNWAMWTLLRCLQIRPDSIAGHSTGDYSAMFASSTVEIAREAEVETILEWSK
AHSELVERVAVPGATLIAVAADSATVRSIIESIGGDLYLAMDNCPHQSVLVGGKISAAQAIEQLRKQGIIYEILPFDRPY
HTPMFQPYAEGTAEAFFARVRVNAPAIETYSCTTASRYPADAEEIRRLFVDHWVGPVRFTETINRMYEDGVRLFVEAGPR
GNLTAFVSDILRGRPHLAMPANVARRSGLTQINHLAGVLAAQGVGMRLEYLYARRDPQFIPWESARPSTPAKVRPAAMKL
TLALPPLTVSPRAPKAEGAVATARNGSETPVPHRVAPEITRPQASPSNGAPAAVAVAPASIHALHSKASSAAVMQEYFKG
MENFLEVETEVMGAFLKRRPATQAASSGTASAPIPAEFPLLGTITALVPGEELTALRQLSQQEDLFLRDHALGGRVSLTD
PDLRPLIVLPLTMSMEILAEAGAALMRRQVLVGMRNVQAHHWIQVDDAPVSLQISANRLANSQNEVTVQVRNTKAGPAPV
IEGIMIFADDYPTSPPSSALPLAAERRSQLASTDLYNGRLMFHGPAFQGVVSVERSGQNGMTGQLRTLPTRHLFRSIPNP
LFVTDPVVLDAAGQLVGFWAAEYLSRGFVVFPYHLDRLTIYGPNPRAGQSLTCRLSVQSTAKESMRSDIEVAGADGAVWM
HLQGWADRRFDPPERFHRAWIAPGEAMISEPWPASLKSLPDGESLECRRVNLLFEESGSLWKDLWASLVLTARERGEFAE
RRGPERRQLEWLAGRTAAKDAVRGFLQKHHAIQLFPADIEITHDEYGRPIARGPWTQSLHASPHVSISHSQNVAVALAYD
GSRGMGYGIDLQAIRELAPDFEASVLTGEEQRHLEVVPANLRAEWILRLWCAKEAVSKALGRGLIEGPASVRILALDART
GDVVATPHGKLAAGVPEAAGRKLSAFTMREGAFVFATAIFEKRTS

Specific function: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism [H]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 WD repeats [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=884, Percent_Identity=25, Blast_Score=171, Evalue=4e-42,
Organism=Homo sapiens, GI8923559, Length=292, Percent_Identity=34.5890410958904, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI223972627, Length=162, Percent_Identity=38.2716049382716, Blast_Score=82, Evalue=4e-15,
Organism=Escherichia coli, GI1787337, Length=290, Percent_Identity=34.1379310344828, Blast_Score=138, Evalue=3e-33,
Organism=Escherichia coli, GI1788663, Length=285, Percent_Identity=31.5789473684211, Blast_Score=110, Evalue=6e-25,
Organism=Escherichia coli, GI1787334, Length=306, Percent_Identity=23.5294117647059, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=818, Percent_Identity=25.3056234718826, Blast_Score=171, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17550940, Length=373, Percent_Identity=26.8096514745308, Blast_Score=134, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71983541, Length=289, Percent_Identity=32.1799307958478, Blast_Score=134, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71983535, Length=266, Percent_Identity=32.7067669172932, Blast_Score=124, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6320904, Length=379, Percent_Identity=27.4406332453826, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24581345, Length=892, Percent_Identity=25.8968609865471, Blast_Score=194, Evalue=4e-49,
Organism=Drosophila melanogaster, GI221330659, Length=472, Percent_Identity=29.4491525423729, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI19920632, Length=472, Percent_Identity=29.4491525423729, Blast_Score=163, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24644341, Length=318, Percent_Identity=32.0754716981132, Blast_Score=143, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR000794
- InterPro:   IPR001242
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 178976; Mature: 178845

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLDSQPDPQPEPSPVRGDIAIVGMSCLFAGAPDLDTYWRNIISKVDSVSDPPAGEWDP
CCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
KIFYDPESKSNDRVYCKRGGYIGDIASFRPLEFGVMPVTVDGGEPDQWLALRVASEALAD
EEEECCCCCCCCEEEEECCCEEECCCCCCCCEECEEEEEECCCCCCHHHHHHHHHHHHCC
GGYTELPKEHLRTEVVLGKGTYVNRGNLTVGYHGMIVEHFLRALKNLHPEYTESEIHAIK
CCCCCCCHHHCCEEEEEECCCEEECCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KELKAGLPPFSADTAPALIGNIIAGRIANRLDLMGPSFTVDAACASALLAIEIGVRDLLS
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
HKYDLVLAGGANVNAPLPTLSLFCQLGALSRGEQIRPFDKQADGTILGEGLGMIVLKRRK
CCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCC
DAERDGNRIYAVIKGVGVASDGRAVHVMAPRVEGEELALRRAYEMAGVAQRTVGLIEAHG
CCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEECC
TATPVGDVVEVQALGRVFGEREGSLPTCAIGSVKSMIGHTMPAAGIAGVIKTALALYHRV
CCCCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LPPTLHCQEPNPALHLERTPFYVNTETRPWIHGAETPRRAGVNSFGFGGINAHVVLEEHP
CCCCEECCCCCCCEEEECCCEEEECCCCCCCCCCCCCHHCCCCCCCCCCCEEEEEEECCC
AELPEARNCQIHWETEVCIIEAESRSGLIDRAARLKEYLSQPAVTLKDLAYSLNTRLEGK
CCCCCCCCCEEEEECEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
PSRLAVIASSTDDLAQKLTLAIARLGDPQCSQIKDNGGTYFFDKPLEGKLAFLFPGEGAQ
CCEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCCEEEEEECCCCCC
YPNLLHDLCLHFPEVRQCFDIADRATLRGNATILPSEFMFPRSILSDTERSEVERALWSL
CHHHHHHHHHCCHHHHHHHHHHHCCEECCCCEECCCHHCCCHHHHCCCHHHHHHHHHHHH
DGAVAAVLIGNWAMWTLLRCLQIRPDSIAGHSTGDYSAMFASSTVEIAREAEVETILEWS
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KAHSELVERVAVPGATLIAVAADSATVRSIIESIGGDLYLAMDNCPHQSVLVGGKISAAQ
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCHHHH
AIEQLRKQGIIYEILPFDRPYHTPMFQPYAEGTAEAFFARVRVNAPAIETYSCTTASRYP
HHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCHHHHHEEEEEECCCCEEEEECCCCCCCC
ADAEEIRRLFVDHWVGPVRFTETINRMYEDGVRLFVEAGPRGNLTAFVSDILRGRPHLAM
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCCCCC
PANVARRSGLTQINHLAGVLAAQGVGMRLEYLYARRDPQFIPWESARPSTPAKVRPAAMK
CHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEE
LTLALPPLTVSPRAPKAEGAVATARNGSETPVPHRVAPEITRPQASPSNGAPAAVAVAPA
EEEECCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCH
SIHALHSKASSAAVMQEYFKGMENFLEVETEVMGAFLKRRPATQAASSGTASAPIPAEFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCC
LLGTITALVPGEELTALRQLSQQEDLFLRDHALGGRVSLTDPDLRPLIVLPLTMSMEILA
HHHHHEECCCCHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCCCCEEEEECHHHHHHHH
EAGAALMRRQVLVGMRNVQAHHWIQVDDAPVSLQISANRLANSQNEVTVQVRNTKAGPAP
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHCCCCCEEEEEEECCCCCCCH
VIEGIMIFADDYPTSPPSSALPLAAERRSQLASTDLYNGRLMFHGPAFQGVVSVERSGQN
HHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCC
GMTGQLRTLPTRHLFRSIPNPLFVTDPVVLDAAGQLVGFWAAEYLSRGFVVFPYHLDRLT
CCCCCHHCCCHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHCCCEEEEEEECEEE
IYGPNPRAGQSLTCRLSVQSTAKESMRSDIEVAGADGAVWMHLQGWADRRFDPPERFHRA
EECCCCCCCCEEEEEEEEHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCCCHHHHHHH
WIAPGEAMISEPWPASLKSLPDGESLECRRVNLLFEESGSLWKDLWASLVLTARERGEFA
HCCCCHHHCCCCCCHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCHH
ERRGPERRQLEWLAGRTAAKDAVRGFLQKHHAIQLFPADIEITHDEYGRPIARGPWTQSL
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCEEECCHHCCCCCCCCCCCCCC
HASPHVSISHSQNVAVALAYDGSRGMGYGIDLQAIRELAPDFEASVLTGEEQRHLEVVPA
CCCCCEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCEEECCCCCCEEEEEEC
NLRAEWILRLWCAKEAVSKALGRGLIEGPASVRILALDARTGDVVATPHGKLAAGVPEAA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCHHH
GRKLSAFTMREGAFVFATAIFEKRTS
CCCEEEEEECCCCEEEEEEHHHHCCC
>Mature Secondary Structure 
TPLDSQPDPQPEPSPVRGDIAIVGMSCLFAGAPDLDTYWRNIISKVDSVSDPPAGEWDP
CCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
KIFYDPESKSNDRVYCKRGGYIGDIASFRPLEFGVMPVTVDGGEPDQWLALRVASEALAD
EEEECCCCCCCCEEEEECCCEEECCCCCCCCEECEEEEEECCCCCCHHHHHHHHHHHHCC
GGYTELPKEHLRTEVVLGKGTYVNRGNLTVGYHGMIVEHFLRALKNLHPEYTESEIHAIK
CCCCCCCHHHCCEEEEEECCCEEECCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KELKAGLPPFSADTAPALIGNIIAGRIANRLDLMGPSFTVDAACASALLAIEIGVRDLLS
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
HKYDLVLAGGANVNAPLPTLSLFCQLGALSRGEQIRPFDKQADGTILGEGLGMIVLKRRK
CCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCC
DAERDGNRIYAVIKGVGVASDGRAVHVMAPRVEGEELALRRAYEMAGVAQRTVGLIEAHG
CCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHEEECC
TATPVGDVVEVQALGRVFGEREGSLPTCAIGSVKSMIGHTMPAAGIAGVIKTALALYHRV
CCCCCCHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LPPTLHCQEPNPALHLERTPFYVNTETRPWIHGAETPRRAGVNSFGFGGINAHVVLEEHP
CCCCEECCCCCCCEEEECCCEEEECCCCCCCCCCCCCHHCCCCCCCCCCCEEEEEEECCC
AELPEARNCQIHWETEVCIIEAESRSGLIDRAARLKEYLSQPAVTLKDLAYSLNTRLEGK
CCCCCCCCCEEEEECEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
PSRLAVIASSTDDLAQKLTLAIARLGDPQCSQIKDNGGTYFFDKPLEGKLAFLFPGEGAQ
CCEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCCEEEEEECCCCCC
YPNLLHDLCLHFPEVRQCFDIADRATLRGNATILPSEFMFPRSILSDTERSEVERALWSL
CHHHHHHHHHCCHHHHHHHHHHHCCEECCCCEECCCHHCCCHHHHCCCHHHHHHHHHHHH
DGAVAAVLIGNWAMWTLLRCLQIRPDSIAGHSTGDYSAMFASSTVEIAREAEVETILEWS
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KAHSELVERVAVPGATLIAVAADSATVRSIIESIGGDLYLAMDNCPHQSVLVGGKISAAQ
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCHHHH
AIEQLRKQGIIYEILPFDRPYHTPMFQPYAEGTAEAFFARVRVNAPAIETYSCTTASRYP
HHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCHHHHHEEEEEECCCCEEEEECCCCCCCC
ADAEEIRRLFVDHWVGPVRFTETINRMYEDGVRLFVEAGPRGNLTAFVSDILRGRPHLAM
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCCCCC
PANVARRSGLTQINHLAGVLAAQGVGMRLEYLYARRDPQFIPWESARPSTPAKVRPAAMK
CHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEE
LTLALPPLTVSPRAPKAEGAVATARNGSETPVPHRVAPEITRPQASPSNGAPAAVAVAPA
EEEECCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCH
SIHALHSKASSAAVMQEYFKGMENFLEVETEVMGAFLKRRPATQAASSGTASAPIPAEFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCC
LLGTITALVPGEELTALRQLSQQEDLFLRDHALGGRVSLTDPDLRPLIVLPLTMSMEILA
HHHHHEECCCCHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCCCCEEEEECHHHHHHHH
EAGAALMRRQVLVGMRNVQAHHWIQVDDAPVSLQISANRLANSQNEVTVQVRNTKAGPAP
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHCCCCCEEEEEEECCCCCCCH
VIEGIMIFADDYPTSPPSSALPLAAERRSQLASTDLYNGRLMFHGPAFQGVVSVERSGQN
HHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCC
GMTGQLRTLPTRHLFRSIPNPLFVTDPVVLDAAGQLVGFWAAEYLSRGFVVFPYHLDRLT
CCCCCHHCCCHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHCCCEEEEEEECEEE
IYGPNPRAGQSLTCRLSVQSTAKESMRSDIEVAGADGAVWMHLQGWADRRFDPPERFHRA
EECCCCCCCCEEEEEEEEHHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCCCHHHHHHH
WIAPGEAMISEPWPASLKSLPDGESLECRRVNLLFEESGSLWKDLWASLVLTARERGEFA
HCCCCHHHCCCCCCHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCHH
ERRGPERRQLEWLAGRTAAKDAVRGFLQKHHAIQLFPADIEITHDEYGRPIARGPWTQSL
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCEEECCHHCCCCCCCCCCCCCC
HASPHVSISHSQNVAVALAYDGSRGMGYGIDLQAIRELAPDFEASVLTGEEQRHLEVVPA
CCCCCEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCEEECCCCCCEEEEEEC
NLRAEWILRLWCAKEAVSKALGRGLIEGPASVRILALDARTGDVVATPHGKLAAGVPEAA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCHHH
GRKLSAFTMREGAFVFATAIFEKRTS
CCCEEEEEECCCCEEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]