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The map label for this gene is quiA [H]

Identifier: 116621067

GI number: 116621067

Start: 2432323

End: 2434587

Strand: Direct

Name: quiA [H]

Synonym: Acid_1948

Alternate gene names: 116621067

Gene position: 2432323-2434587 (Clockwise)

Preceding gene: 116621066

Following gene: 116621068

Centisome position: 24.41

GC content: 62.47

Gene sequence:

>2265_bases
ATGAAAGCCACCATGAAAATACACACCATCATCGCGGTCCTGGCATTGTTCACTGTTTCCGCCGAAAGAGCGTCCGGGCA
GAAGGAGAGCGGGGGCTGGAAGGACTATCTGGGGGGGCCGGACGGCTCGCACTATTCTCCCTTGACGCAGATCAACGCTT
CGAATGTGAGCAGGATGGAAGTGGCCTGGAGCTATCCGGCGCCGGACGGGACTTCCGTGTTCTGCCCGCTGGTTGTAGAT
AACGTCGCATACCTCGCCGCCAAAGGCGGAGCGTTAGTCGCGCTGGACGCGACCACTGGCAAGGAACTCTGGGCGCATTC
GTTCGGCACTGGCGGCGGGGGGCGGGGCGGCATCAGCGGGCAGCGCGGCGCGAACTACTGGGAGAGCAAGGACCGCAAAG
ATCGCCGCATCTTGGTTACCGCGAGCGGTTTTCTGCACGCCATCGATGCGCTGACCGGCAAGACGATCGAGTCGTTCGCC
GATCACGGGAAGCTGGATCTGAAGATCGGAATCGACCGTGCGCCGATCCCGCTGGCGTCCAGAACTCCCGGGCGCATTTT
CGAGAATCTGATCATTCTTGGGAGCTTCCCCGGCGAAGGTTACCTCGCGCCGCCGGGAGATCTCCGCGCCTTCGATGTGC
GCACGGGCAAGCTGGCCTGGGTATTCCATACCATTCCGCACGAGGGCGAACTCGGGTACGACACGTGGCCGAAGGACGCG
TACAAGTACATGGGCGGCGTGGACGTATGGGGCGAAATCACCGTGGACGAAAAGCGCGGGATCGCGTATTTTCCGGTATC
GTCGGCCAAGTACGAACTGTACGGCGGTGATCGCCCGGGCAACAATCTTTTCGCCGACTGCCTCCTCGCGCTGGACGCGC
GCACCGGCAAATACCTGTGGCACTTCCAAACCGTGCATCACGACATCTGGGATTACGATCCGACGGCTGCCCCGCAACTG
GTGACCGCAAAGCATGACGGCAAGACTGTGGATGTGGTGGCGCTCGCGTCGAAAAATGGCTTTCTGTATGTGTTCGATCG
CGTGACCGGCAAGCCGCTGTGGCCGATCGAGGAGCGGGCGGTGCCGAAATCGGAAGTGCCGGGCGAGTGGACGTCGCCGA
CGCAGCCCTTTCCCACCATGCCGCCTCCGTTTGCCCGGCAGCGCATGACAAAGGACGACCTCTACTTCGGCTTCATGACT
CCGGAGGAGAAGACGCACTGGGAAGAGCGTTTCGCCAAGGCGCAGAACCATGGGCTTTTCACGCCGCCTGGCTTGACCGA
CACAGTTTCCATACCGGGCGTGAACGGCGGTCCGTTCTTTTGGGACACGGGAGCCGATCCGGCAAGAGGAATTGTCTTCG
TGGAGTCGAAGGACTTTCCGTCCATCTTGAAAATGGTGAAGGCGGGGGAATCGACGTCATCGAATTCAGGCGGCTCGATC
CCGAGCCGCACGCAGCCGGGCGGCGGACGCGGACGCGGCGGCTTCGGCATGACCGGCGGCCCACCCATGGCGCTAAGGCT
TGGTCGCACGATTTACGAGGGCTCCTGCCAGGCTTGTCACGGTCCGGATTTAAAGGGCGACCGTGGGCCGGCGGTGGACG
ACGCGGTGAAGCGGCTGGGTATGGCCGCGGTGCTCACCATCGTGAAGAAAGGCAAGGGTGCGATGCCGGGCTTCCCGACC
ATGAACGCCGAAGCCATCACCGATGTCGTCGAGTTCCTGGATAAATCGGATCAGGCCCCGGCGGGCACCGGTGTTCCGGG
CAATAGCCTAATGGAGCGGCTGGAGCCGGACTATCCTGCCGGAGTCATGCCGCCGCCTTCGCGTTTTAAGACCGGCTACG
GCCAGGAAGGCTACATCCTTACGCCGCCGTGGAGCACGATTACGGCTTACGACCTCAACACCGGCAAGATCATTTGGCAG
ACGCCCTATGGCGATACGCCGCAGGCCGGACCGAGTGACAAGTTGCGCGGGAACGTCACCCCTAGAAGCGGCTTCGTGGT
AACGGCGGGCGGGCTAGTGCTGTTTGCGGATAACCAGTCGAAGCTGTATGCGCTGGATAAGAATACCGGGAAAGTGGTCC
ATTCGCGCGATGTGCCGAATAGCGCGGTGGGTGTTCCGGCGGTGTACGAGGTCAACGGACGTGAGTACATCCTGTTTTCG
TTGCTCGGCGGGCCGGGCTTCCCCGCGGGCGCCCGCATGGCCCCAGGCGGCGTGAATCCGCCGCCGGGCGAAAAGATGTT
TGTGGCATTTGCGCTGCCGAAGTGA

Upstream 100 bases:

>100_bases
TCGAACTCGACGGCGGACCGCGAATGCCGATGACTGCGCTCGAGACGGCAACGATCGCAAAGGCGTACCTGGAAAAACAG
GGCATTGCTTTTCGCAACGC

Downstream 100 bases:

>100_bases
TCAAGAGCGAGGAGAACCGTTATGTTGAAGAAGTTCGCTTATGTATCCGCGGCGATAGGCGCCCTGTTCCTGCTGTTGCG
TCCCGCTGGGGCGAACAAGA

Product: pyrrolo-quinoline quinone

Products: NA

Alternate protein names: NAD(P)-independent quinate dehydrogenase [H]

Number of amino acids: Translated: 754; Mature: 754

Protein sequence:

>754_residues
MKATMKIHTIIAVLALFTVSAERASGQKESGGWKDYLGGPDGSHYSPLTQINASNVSRMEVAWSYPAPDGTSVFCPLVVD
NVAYLAAKGGALVALDATTGKELWAHSFGTGGGGRGGISGQRGANYWESKDRKDRRILVTASGFLHAIDALTGKTIESFA
DHGKLDLKIGIDRAPIPLASRTPGRIFENLIILGSFPGEGYLAPPGDLRAFDVRTGKLAWVFHTIPHEGELGYDTWPKDA
YKYMGGVDVWGEITVDEKRGIAYFPVSSAKYELYGGDRPGNNLFADCLLALDARTGKYLWHFQTVHHDIWDYDPTAAPQL
VTAKHDGKTVDVVALASKNGFLYVFDRVTGKPLWPIEERAVPKSEVPGEWTSPTQPFPTMPPPFARQRMTKDDLYFGFMT
PEEKTHWEERFAKAQNHGLFTPPGLTDTVSIPGVNGGPFFWDTGADPARGIVFVESKDFPSILKMVKAGESTSSNSGGSI
PSRTQPGGGRGRGGFGMTGGPPMALRLGRTIYEGSCQACHGPDLKGDRGPAVDDAVKRLGMAAVLTIVKKGKGAMPGFPT
MNAEAITDVVEFLDKSDQAPAGTGVPGNSLMERLEPDYPAGVMPPPSRFKTGYGQEGYILTPPWSTITAYDLNTGKIIWQ
TPYGDTPQAGPSDKLRGNVTPRSGFVVTAGGLVLFADNQSKLYALDKNTGKVVHSRDVPNSAVGVPAVYEVNGREYILFS
LLGGPGFPAGARMAPGGVNPPPGEKMFVAFALPK

Sequences:

>Translated_754_residues
MKATMKIHTIIAVLALFTVSAERASGQKESGGWKDYLGGPDGSHYSPLTQINASNVSRMEVAWSYPAPDGTSVFCPLVVD
NVAYLAAKGGALVALDATTGKELWAHSFGTGGGGRGGISGQRGANYWESKDRKDRRILVTASGFLHAIDALTGKTIESFA
DHGKLDLKIGIDRAPIPLASRTPGRIFENLIILGSFPGEGYLAPPGDLRAFDVRTGKLAWVFHTIPHEGELGYDTWPKDA
YKYMGGVDVWGEITVDEKRGIAYFPVSSAKYELYGGDRPGNNLFADCLLALDARTGKYLWHFQTVHHDIWDYDPTAAPQL
VTAKHDGKTVDVVALASKNGFLYVFDRVTGKPLWPIEERAVPKSEVPGEWTSPTQPFPTMPPPFARQRMTKDDLYFGFMT
PEEKTHWEERFAKAQNHGLFTPPGLTDTVSIPGVNGGPFFWDTGADPARGIVFVESKDFPSILKMVKAGESTSSNSGGSI
PSRTQPGGGRGRGGFGMTGGPPMALRLGRTIYEGSCQACHGPDLKGDRGPAVDDAVKRLGMAAVLTIVKKGKGAMPGFPT
MNAEAITDVVEFLDKSDQAPAGTGVPGNSLMERLEPDYPAGVMPPPSRFKTGYGQEGYILTPPWSTITAYDLNTGKIIWQ
TPYGDTPQAGPSDKLRGNVTPRSGFVVTAGGLVLFADNQSKLYALDKNTGKVVHSRDVPNSAVGVPAVYEVNGREYILFS
LLGGPGFPAGARMAPGGVNPPPGEKMFVAFALPK
>Mature_754_residues
MKATMKIHTIIAVLALFTVSAERASGQKESGGWKDYLGGPDGSHYSPLTQINASNVSRMEVAWSYPAPDGTSVFCPLVVD
NVAYLAAKGGALVALDATTGKELWAHSFGTGGGGRGGISGQRGANYWESKDRKDRRILVTASGFLHAIDALTGKTIESFA
DHGKLDLKIGIDRAPIPLASRTPGRIFENLIILGSFPGEGYLAPPGDLRAFDVRTGKLAWVFHTIPHEGELGYDTWPKDA
YKYMGGVDVWGEITVDEKRGIAYFPVSSAKYELYGGDRPGNNLFADCLLALDARTGKYLWHFQTVHHDIWDYDPTAAPQL
VTAKHDGKTVDVVALASKNGFLYVFDRVTGKPLWPIEERAVPKSEVPGEWTSPTQPFPTMPPPFARQRMTKDDLYFGFMT
PEEKTHWEERFAKAQNHGLFTPPGLTDTVSIPGVNGGPFFWDTGADPARGIVFVESKDFPSILKMVKAGESTSSNSGGSI
PSRTQPGGGRGRGGFGMTGGPPMALRLGRTIYEGSCQACHGPDLKGDRGPAVDDAVKRLGMAAVLTIVKKGKGAMPGFPT
MNAEAITDVVEFLDKSDQAPAGTGVPGNSLMERLEPDYPAGVMPPPSRFKTGYGQEGYILTPPWSTITAYDLNTGKIIWQ
TPYGDTPQAGPSDKLRGNVTPRSGFVVTAGGLVLFADNQSKLYALDKNTGKVVHSRDVPNSAVGVPAVYEVNGREYILFS
LLGGPGFPAGARMAPGGVNPPPGEKMFVAFALPK

Specific function: Can act either on quinate or on shikimate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=466, Percent_Identity=30.68669527897, Blast_Score=188, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.99.25 [H]

Molecular weight: Translated: 80829; Mature: 80829

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATMKIHTIIAVLALFTVSAERASGQKESGGWKDYLGGPDGSHYSPLTQINASNVSRME
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCEEECCCCCEEEE
VAWSYPAPDGTSVFCPLVVDNVAYLAAKGGALVALDATTGKELWAHSFGTGGGGRGGISG
EEEECCCCCCCEEECHHHHHCHHHEEECCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCC
QRGANYWESKDRKDRRILVTASGFLHAIDALTGKTIESFADHGKLDLKIGIDRAPIPLAS
CCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCCCCCC
RTPGRIFENLIILGSFPGEGYLAPPGDLRAFDVRTGKLAWVFHTIPHEGELGYDTWPKDA
CCHHHHHCCEEEEECCCCCCEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCHHH
YKYMGGVDVWGEITVDEKRGIAYFPVSSAKYELYGGDRPGNNLFADCLLALDARTGKYLW
HHHCCCCCEEEEEEEECCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEE
HFQTVHHDIWDYDPTAAPQLVTAKHDGKTVDVVALASKNGFLYVFDRVTGKPLWPIEERA
EEEEHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHC
VPKSEVPGEWTSPTQPFPTMPPPFARQRMTKDDLYFGFMTPEEKTHWEERFAKAQNHGLF
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCC
TPPGLTDTVSIPGVNGGPFFWDTGADPARGIVFVESKDFPSILKMVKAGESTSSNSGGSI
CCCCCCCEEECCCCCCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCC
PSRTQPGGGRGRGGFGMTGGPPMALRLGRTIYEGSCQACHGPDLKGDRGPAVDDAVKRLG
CCCCCCCCCCCCCCCCCCCCCCHHEECCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
MAAVLTIVKKGKGAMPGFPTMNAEAITDVVEFLDKSDQAPAGTGVPGNSLMERLEPDYPA
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCC
GVMPPPSRFKTGYGQEGYILTPPWSTITAYDLNTGKIIWQTPYGDTPQAGPSDKLRGNVT
CCCCCCHHHCCCCCCCCEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCC
PRSGFVVTAGGLVLFADNQSKLYALDKNTGKVVHSRDVPNSAVGVPAVYEVNGREYILFS
CCCCEEEEECCEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEE
LLGGPGFPAGARMAPGGVNPPPGEKMFVAFALPK
EECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MKATMKIHTIIAVLALFTVSAERASGQKESGGWKDYLGGPDGSHYSPLTQINASNVSRME
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCEEECCCCCEEEE
VAWSYPAPDGTSVFCPLVVDNVAYLAAKGGALVALDATTGKELWAHSFGTGGGGRGGISG
EEEECCCCCCCEEECHHHHHCHHHEEECCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCC
QRGANYWESKDRKDRRILVTASGFLHAIDALTGKTIESFADHGKLDLKIGIDRAPIPLAS
CCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCCCCCC
RTPGRIFENLIILGSFPGEGYLAPPGDLRAFDVRTGKLAWVFHTIPHEGELGYDTWPKDA
CCHHHHHCCEEEEECCCCCCEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCHHH
YKYMGGVDVWGEITVDEKRGIAYFPVSSAKYELYGGDRPGNNLFADCLLALDARTGKYLW
HHHCCCCCEEEEEEEECCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEE
HFQTVHHDIWDYDPTAAPQLVTAKHDGKTVDVVALASKNGFLYVFDRVTGKPLWPIEERA
EEEEHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHC
VPKSEVPGEWTSPTQPFPTMPPPFARQRMTKDDLYFGFMTPEEKTHWEERFAKAQNHGLF
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCC
TPPGLTDTVSIPGVNGGPFFWDTGADPARGIVFVESKDFPSILKMVKAGESTSSNSGGSI
CCCCCCCEEECCCCCCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCC
PSRTQPGGGRGRGGFGMTGGPPMALRLGRTIYEGSCQACHGPDLKGDRGPAVDDAVKRLG
CCCCCCCCCCCCCCCCCCCCCCHHEECCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
MAAVLTIVKKGKGAMPGFPTMNAEAITDVVEFLDKSDQAPAGTGVPGNSLMERLEPDYPA
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCC
GVMPPPSRFKTGYGQEGYILTPPWSTITAYDLNTGKIIWQTPYGDTPQAGPSDKLRGNVT
CCCCCCHHHCCCCCCCCEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCC
PRSGFVVTAGGLVLFADNQSKLYALDKNTGKVVHSRDVPNSAVGVPAVYEVNGREYILFS
CCCCEEEEECCEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEE
LLGGPGFPAGARMAPGGVNPPPGEKMFVAFALPK
EECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002591; 7592351 [H]