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The map label for this gene is resE [H]

Identifier: 116620970

GI number: 116620970

Start: 2304100

End: 2306007

Strand: Direct

Name: resE [H]

Synonym: Acid_1851

Alternate gene names: 116620970

Gene position: 2304100-2306007 (Clockwise)

Preceding gene: 116620969

Following gene: 116620971

Centisome position: 23.12

GC content: 60.64

Gene sequence:

>1908_bases
GTGCGTTTTCCTTTTCGTGTGGGCTGGAACAGTACGGCGTCATACGTGGGGCTGCTGCTGGCCTCCTTCGCTCTAGCCCT
ATTCACCAGCTACATCCTCGGATCCCAACTCAACATCTGGGCGTACGACGCCATGTACCGCGCCTACCGGCCGCCGGCGA
TCCAGCCGGAATCGGTGGTGCTCGCGATCGACGAGCTTACCCTGGTGCAGTGCGGCGGCATTCGCGGCATCCGGCGTCCC
ATCGCGGAGGCGCTGCGAATCCTGGCGCCGGCCAAGCCCAAGGTGGTCGCGATTGACGTAATCCTGGCCGATAAAGGCGA
TGAGGTCGGCGATGCCGCGCTCTCCGCGGCGCTTCACGCTACGCCCAACCTGGTGCTTTCCACCGAACTGATCGATGGCG
ACCGCATCTGGGAAGATCCGCGGCCGGAGTTTATGGGCAAGGCCAAATTAGGACATGTTTCGGCCGTGCCCGATAAAGAA
GACATGGTCACGCGCAAGATTCTCCTTTACCAGCACAGCGCGCGGGAGCAGCGCGGCGCGCTCGCGCTGGAGGCGTTTCT
GCTGAGCCGTGGCGTCGCGACCCCGCGCGAGTCGCTCGAATTCACGGCGCTTCGCGGCGGCCTGGCGAGCGCGGAGTTAC
AGGTCGGCGACGTGACGATCCCGGTGCTCGAGGACAAGCGCGAGAAGCGCCGCTTCATGCGCGTTCACTTTTTCCCGCCG
GGGTCCACCGTGCCGATCGTCTCCATGCGGCGCCTGTTGGACGATCCGAGTCTGGCCGCGCAGTTTGCCGGAAAGGTAGT
CTTCATCGGCGTCACGGCGAACTCGGAGGTGCAGGATCGCCTGTTCACTCCGGTGGGACGCACAGCCGGTATCGAGATCA
ACGCCGCGGCGTTTGAGACGATGGCCCACCGGTTATTCTTTACAGATGTCACGCCAATACAGGAGGACCTGATCGTATTG
GCCCTGTTGGCCGCGATCGGCCTCGCCTTTCGGTATCTTCCGGGTTGGTGGGCCTACGCCGCCGGAGCGATTATTCTCTT
CAGCGCGTCGATCATCCCGTACGTCTTTTTCCAGCACCACCTCGTCTTTCCATTTGCGACTTCTTTCCTGGTGGCGTGGA
TGGGCACACTTACAGCGGCGTCTTACTATCACCTCGTAGTGCGGCGTAACCTGCGTGTGGAGCAAGCCTCGCGCGAGCGG
TATCAGCAGGCGATGCACTTCGTCACCCACGAAATGCGCACCCCGCTTTCCGCCATCCAGGGCTCGAGCGAATTGATCTC
GCGCTACTCCTTGACGGAAGAAAAACGGCAGCAGATCGCGCTGCTGATCAACTCCGAATCCAAGCGGCTGGCGCGGATGG
TGGAGATTTTTCTCAATGTGGAGCGCCTCTCGGCCGGGCAGATGGAACTGAAGCGCGAGGCGATTTCCGTGAAGGAGATG
ATGGAGGTCTGCGTTCAACGCGTGACTCCCCTGGCCGAGCGCAAACATATCGCAATAACACTGGAACCGGTGCCTGAGAA
TCTGAGTGTTACCGGCGATCGCGAACTGATGGAGTACGCTTGCTACAATTTACTTACTAATGCCGTAAAATACTCGCCTC
AGCGCACGGAGGTGACCGCCTCCGCCTGGAGAGACGATTCCCTGGTTCGCATTGCGGTGAAAGATCAGGGCATTGGGATG
GATCAGAAGGAAGTCAAGCAGATCTTCCAGAAGTTTTACCGCACTAAAAAAGCGGAAGAATCCGGCGAGGCAGGCACCGG
AATCGGGCTGTCGATCGTCCAACAGATAATAGAACAACACGGAGGAAAAATTGAAGTGACCAGCCGGCCGGGCGCCGGGA
GTTGCTTCACGGTGGTGGTGCCGGCGCGAGCGCTTGCCCCGGTTTCGACGGCCGCGGAACGACATTGA

Upstream 100 bases:

>100_bases
ACCTTCTCCAGCTTCGTCGGCACCGGCGCCACCGTTACCTGGCAGTAGACGTTTCACCCTCAAAAGACGCACTTCTTCCT
CCCGGTATACTGGGGAAGAA

Downstream 100 bases:

>100_bases
TGCAGAAAATTCTCTTAGTGGAAGATGATCCGGCGCTTCAATTCACCATCCAGACGTTTCTGGAGGCGAACGGATACGCG
GTTGACGCTGTGTCAACAAC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MRFPFRVGWNSTASYVGLLLASFALALFTSYILGSQLNIWAYDAMYRAYRPPAIQPESVVLAIDELTLVQCGGIRGIRRP
IAEALRILAPAKPKVVAIDVILADKGDEVGDAALSAALHATPNLVLSTELIDGDRIWEDPRPEFMGKAKLGHVSAVPDKE
DMVTRKILLYQHSAREQRGALALEAFLLSRGVATPRESLEFTALRGGLASAELQVGDVTIPVLEDKREKRRFMRVHFFPP
GSTVPIVSMRRLLDDPSLAAQFAGKVVFIGVTANSEVQDRLFTPVGRTAGIEINAAAFETMAHRLFFTDVTPIQEDLIVL
ALLAAIGLAFRYLPGWWAYAAGAIILFSASIIPYVFFQHHLVFPFATSFLVAWMGTLTAASYYHLVVRRNLRVEQASRER
YQQAMHFVTHEMRTPLSAIQGSSELISRYSLTEEKRQQIALLINSESKRLARMVEIFLNVERLSAGQMELKREAISVKEM
MEVCVQRVTPLAERKHIAITLEPVPENLSVTGDRELMEYACYNLLTNAVKYSPQRTEVTASAWRDDSLVRIAVKDQGIGM
DQKEVKQIFQKFYRTKKAEESGEAGTGIGLSIVQQIIEQHGGKIEVTSRPGAGSCFTVVVPARALAPVSTAAERH

Sequences:

>Translated_635_residues
MRFPFRVGWNSTASYVGLLLASFALALFTSYILGSQLNIWAYDAMYRAYRPPAIQPESVVLAIDELTLVQCGGIRGIRRP
IAEALRILAPAKPKVVAIDVILADKGDEVGDAALSAALHATPNLVLSTELIDGDRIWEDPRPEFMGKAKLGHVSAVPDKE
DMVTRKILLYQHSAREQRGALALEAFLLSRGVATPRESLEFTALRGGLASAELQVGDVTIPVLEDKREKRRFMRVHFFPP
GSTVPIVSMRRLLDDPSLAAQFAGKVVFIGVTANSEVQDRLFTPVGRTAGIEINAAAFETMAHRLFFTDVTPIQEDLIVL
ALLAAIGLAFRYLPGWWAYAAGAIILFSASIIPYVFFQHHLVFPFATSFLVAWMGTLTAASYYHLVVRRNLRVEQASRER
YQQAMHFVTHEMRTPLSAIQGSSELISRYSLTEEKRQQIALLINSESKRLARMVEIFLNVERLSAGQMELKREAISVKEM
MEVCVQRVTPLAERKHIAITLEPVPENLSVTGDRELMEYACYNLLTNAVKYSPQRTEVTASAWRDDSLVRIAVKDQGIGM
DQKEVKQIFQKFYRTKKAEESGEAGTGIGLSIVQQIIEQHGGKIEVTSRPGAGSCFTVVVPARALAPVSTAAERH
>Mature_635_residues
MRFPFRVGWNSTASYVGLLLASFALALFTSYILGSQLNIWAYDAMYRAYRPPAIQPESVVLAIDELTLVQCGGIRGIRRP
IAEALRILAPAKPKVVAIDVILADKGDEVGDAALSAALHATPNLVLSTELIDGDRIWEDPRPEFMGKAKLGHVSAVPDKE
DMVTRKILLYQHSAREQRGALALEAFLLSRGVATPRESLEFTALRGGLASAELQVGDVTIPVLEDKREKRRFMRVHFFPP
GSTVPIVSMRRLLDDPSLAAQFAGKVVFIGVTANSEVQDRLFTPVGRTAGIEINAAAFETMAHRLFFTDVTPIQEDLIVL
ALLAAIGLAFRYLPGWWAYAAGAIILFSASIIPYVFFQHHLVFPFATSFLVAWMGTLTAASYYHLVVRRNLRVEQASRER
YQQAMHFVTHEMRTPLSAIQGSSELISRYSLTEEKRQQIALLINSESKRLARMVEIFLNVERLSAGQMELKREAISVKEM
MEVCVQRVTPLAERKHIAITLEPVPENLSVTGDRELMEYACYNLLTNAVKYSPQRTEVTASAWRDDSLVRIAVKDQGIGM
DQKEVKQIFQKFYRTKKAEESGEAGTGIGLSIVQQIIEQHGGKIEVTSRPGAGSCFTVVVPARALAPVSTAAERH

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=28.3783783783784, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788713, Length=240, Percent_Identity=27.0833333333333, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=29.8701298701299, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=31.6017316017316, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1790436, Length=267, Percent_Identity=28.4644194756554, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=26.8292682926829, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=28.3400809716599, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790346, Length=220, Percent_Identity=28.6363636363636, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=31.2217194570136, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=25.5506607929515, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1786783, Length=215, Percent_Identity=26.046511627907, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=26.2931034482759, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=206, Percent_Identity=27.6699029126214, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=26.4822134387352, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789403, Length=204, Percent_Identity=28.4313725490196, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787374, Length=243, Percent_Identity=25.1028806584362, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790551, Length=206, Percent_Identity=28.1553398058252, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=23.4513274336283, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=24.2424242424242, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=27.0161290322581, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=217, Percent_Identity=24.8847926267281, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70410; Mature: 70410

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFPFRVGWNSTASYVGLLLASFALALFTSYILGSQLNIWAYDAMYRAYRPPAIQPESVV
CCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCCCEE
LAIDELTLVQCGGIRGIRRPIAEALRILAPAKPKVVAIDVILADKGDEVGDAALSAALHA
EEECCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHC
TPNLVLSTELIDGDRIWEDPRPEFMGKAKLGHVSAVPDKEDMVTRKILLYQHSAREQRGA
CCCEEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LALEAFLLSRGVATPRESLEFTALRGGLASAELQVGDVTIPVLEDKREKRRFMRVHFFPP
HHHHHHHHHCCCCCCHHCCCHHHHHCCCCCCEEEECCEEEEHHCCHHHHCCEEEEEEECC
GSTVPIVSMRRLLDDPSLAAQFAGKVVFIGVTANSEVQDRLFTPVGRTAGIEINAAAFET
CCCCHHHHHHHHHCCHHHHHHHCCCEEEEEEECCCHHHHHHCCCCCCCCCCEEEHHHHHH
MAHRLFFTDVTPIQEDLIVLALLAAIGLAFRYLPGWWAYAAGAIILFSASIIPYVFFQHH
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVFPFATSFLVAWMGTLTAASYYHLVVRRNLRVEQASRERYQQAMHFVTHEMRTPLSAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHC
GSSELISRYSLTEEKRQQIALLINSESKRLARMVEIFLNVERLSAGQMELKREAISVKEM
CCHHHHHHHHCCHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MEVCVQRVTPLAERKHIAITLEPVPENLSVTGDRELMEYACYNLLTNAVKYSPQRTEVTA
HHHHHHHCCCHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEH
SAWRDDSLVRIAVKDQGIGMDQKEVKQIFQKFYRTKKAEESGEAGTGIGLSIVQQIIEQH
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHC
GGKIEVTSRPGAGSCFTVVVPARALAPVSTAAERH
CCEEEEECCCCCCCEEEEEECHHHHCCHHHHHCCC
>Mature Secondary Structure
MRFPFRVGWNSTASYVGLLLASFALALFTSYILGSQLNIWAYDAMYRAYRPPAIQPESVV
CCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCCCEE
LAIDELTLVQCGGIRGIRRPIAEALRILAPAKPKVVAIDVILADKGDEVGDAALSAALHA
EEECCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHC
TPNLVLSTELIDGDRIWEDPRPEFMGKAKLGHVSAVPDKEDMVTRKILLYQHSAREQRGA
CCCEEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LALEAFLLSRGVATPRESLEFTALRGGLASAELQVGDVTIPVLEDKREKRRFMRVHFFPP
HHHHHHHHHCCCCCCHHCCCHHHHHCCCCCCEEEECCEEEEHHCCHHHHCCEEEEEEECC
GSTVPIVSMRRLLDDPSLAAQFAGKVVFIGVTANSEVQDRLFTPVGRTAGIEINAAAFET
CCCCHHHHHHHHHCCHHHHHHHCCCEEEEEEECCCHHHHHHCCCCCCCCCCEEEHHHHHH
MAHRLFFTDVTPIQEDLIVLALLAAIGLAFRYLPGWWAYAAGAIILFSASIIPYVFFQHH
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVFPFATSFLVAWMGTLTAASYYHLVVRRNLRVEQASRERYQQAMHFVTHEMRTPLSAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHC
GSSELISRYSLTEEKRQQIALLINSESKRLARMVEIFLNVERLSAGQMELKREAISVKEM
CCHHHHHHHHCCHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MEVCVQRVTPLAERKHIAITLEPVPENLSVTGDRELMEYACYNLLTNAVKYSPQRTEVTA
HHHHHHHCCCHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEH
SAWRDDSLVRIAVKDQGIGMDQKEVKQIFQKFYRTKKAEESGEAGTGIGLSIVQQIIEQH
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHC
GGKIEVTSRPGAGSCFTVVVPARALAPVSTAAERH
CCEEEEECCCCCCCEEEEEECHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]