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The map label for this gene is yuxL [H]

Identifier: 116620945

GI number: 116620945

Start: 2272974

End: 2274977

Strand: Reverse

Name: yuxL [H]

Synonym: Acid_1826

Alternate gene names: 116620945

Gene position: 2274977-2272974 (Counterclockwise)

Preceding gene: 116620946

Following gene: 116620944

Centisome position: 22.83

GC content: 64.82

Gene sequence:

>2004_bases
ATGCGCCTCATCGCCCTTTGTGCCCTCGCCCTTACTGCGTCCGCACAACCCAGCCTCGACCGACTACTGAGCGCCGCATT
CCCCTCGGAACTCACCGCCGCTCCGGCAGGGGGCAAGGTCGCCTGGGTCTCTAACGCCAAAGGGCTGCGCAACATAATGG
TCGCCGAGCCTCCGGCCTACGTTGGGCGCAAGATTACCACTTACGCGGCCGACGACGGCCAGGAGATCAGCGACCTTCGC
TGGACACCGGACTCATCCGCGATCGTTTACGTCCGCGGCGGATCGGCGAATCCCGCGCTCGACCCCGCCGGCGTGACGCA
AGCGATCTGGAGGGCCGCGCTGGATGGGACGGCGGCGCGGAAGATCGGGGAAGGCAACGCGCCCGCGGTTTCGCCCAAGG
GCGATAAGGTAGTCTTCATTCGCGCCGGACAGTTGTGGTGGGCGCCGCTGGATGGAAAGGCCGAGGCCTCGCAGGTCTTT
CAGGCCAGGGGCGCTTGCGACCGTCCGCGCTGGTCGCCGGACGGAGCGCGGATCTCCTTTACGAGCGCGCGCGGCGATCA
CGGATTCATCGGCGTCTTCGACGTGGCTGCCGGCGCGCTTCGCTATCTCGACCCCAGCACGGATAACGATAGCGAGCCCG
AATGGTCGCCGGACGGCCGCAGTGTCGCGTTCCTGCGCGTGCCTTCGAGCGGCGTGCGCATGCCGCGCGAGCCGCACCGC
ACAGGCGAGCCGTGGTCGATCCGCATTGCCGACGCGCACACCGGAGCGGGACGGGAAGTTTTCCATGCCCGTGAAGGCGC
GGGCAGCGTCTTCCGCGGCGTGAACGCGCGCAATCAGATTCTCTGGGCCGATGGCAACCGGCTCGTCTTCCCGTGGGAGC
CCGAGGGCTGGACGCACCTCTATGCCGTCTCGACCGAAGGCGGCAAGGCCACGCTGCTCACGCCCGGCAAGTTCGAAGTG
GAGGACGTGGCGGTGTCCGGGAAGCAGGTCCTCTACTCCTCCAATCAGGACGATATCGACCGGCGTCACCTTTGGAAGGT
CGCGGCGGATGGAGGCGTTCCGACGGCGATCACCAGCGGGCAGGGCATCGAGTGCCAGCCCGCGCCGACCAGCGATCCGA
ACGTGATCACCTTTTTGAGGTCGGATGCGCAGCGGCCATTGCGGGCCGCTGTCAGCGTGGCAGGCGCGGCGCGCGATCTG
GATCCGGGTGCGATCCCGAGTGATTTCCCCACGTCGCTGGCGACGCCGCAGCAGGTGGTGTTTCCAGCCGGCGACGGTCT
CGCCATCCACGGGCAGCTCTTTCTTCCCACAAAGAAACCAACCGACGGCCGCTCGCCGGCAATCGTCTTCTTTCACGGCG
GATCGCGGCGGCAGATGCTGCTCGGCTGGCATTACATGTACTACTACGCGAATGCCTACGCGATGAATCAGTACCTCGCG
AGCCTCGGCTATGTGGTGCTCAGCGTCAATTACCGGAGCGGGATCGGCTATGGCTCGGATTTCCGCGAGGCAGTGAATTA
CGGCGCGAACGGCGGCACCGAGTACAACGACGTTCAGGGCGCCGGCATTTATCTACAGGGGCGTACCGACGTGGACGGCG
GGCGGATCGGCGTCTGGGGCGGCTCTTATGGCGGCTATCTCACCGCGATGGCGCTGGCGCGGGCGAGCGATATGTACAAA
GTCGGCGTGGATTTCCACGGCGTGCATAATTGGGCGACCGAACTGGGGATCCCGGTGACGGCGCCGGACTATAAGATCGC
GTTCGAATCGTCGCCCATGAACTTTCTGAAGACCTGGCAGTCACCAGTGCTGCTCATTCAAGGCGATGACGATCCCGATG
TGCAGTTCAATCAGACGGTGATGCTGGCGGATGCGCTGCGTAAGCAGGGGGTCGAGATCGAAGAGATGGTGATTCCCGAC
GAGGTCCACGATTTTCTGCTGCATCGGAGTTGGCTGACAACATACAAGGCTACGGCGGAGTTCTTACGGCGGCATTTGAA
GTAG

Upstream 100 bases:

>100_bases
GTTGATCCGCACGCGGACGATGAATGGAGTAGCGGGTGAATCGACCATCGTTGCGAGTCGCGTGTTGGGCGAGTAGTTCG
CGAACCACTATCATAAAGTT

Downstream 100 bases:

>100_bases
GCGTGCCGCGAGGCGGTCGCGGCTCGTTGGGGTTTAGGCGTGGGAGCACATCGGTACGGAAACTGCTGGTCATACCGTAT
GATCTTCCAAAGGAAACGCC

Product: peptidase S9 prolyl oligopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MRLIALCALALTASAQPSLDRLLSAAFPSELTAAPAGGKVAWVSNAKGLRNIMVAEPPAYVGRKITTYAADDGQEISDLR
WTPDSSAIVYVRGGSANPALDPAGVTQAIWRAALDGTAARKIGEGNAPAVSPKGDKVVFIRAGQLWWAPLDGKAEASQVF
QARGACDRPRWSPDGARISFTSARGDHGFIGVFDVAAGALRYLDPSTDNDSEPEWSPDGRSVAFLRVPSSGVRMPREPHR
TGEPWSIRIADAHTGAGREVFHAREGAGSVFRGVNARNQILWADGNRLVFPWEPEGWTHLYAVSTEGGKATLLTPGKFEV
EDVAVSGKQVLYSSNQDDIDRRHLWKVAADGGVPTAITSGQGIECQPAPTSDPNVITFLRSDAQRPLRAAVSVAGAARDL
DPGAIPSDFPTSLATPQQVVFPAGDGLAIHGQLFLPTKKPTDGRSPAIVFFHGGSRRQMLLGWHYMYYYANAYAMNQYLA
SLGYVVLSVNYRSGIGYGSDFREAVNYGANGGTEYNDVQGAGIYLQGRTDVDGGRIGVWGGSYGGYLTAMALARASDMYK
VGVDFHGVHNWATELGIPVTAPDYKIAFESSPMNFLKTWQSPVLLIQGDDDPDVQFNQTVMLADALRKQGVEIEEMVIPD
EVHDFLLHRSWLTTYKATAEFLRRHLK

Sequences:

>Translated_667_residues
MRLIALCALALTASAQPSLDRLLSAAFPSELTAAPAGGKVAWVSNAKGLRNIMVAEPPAYVGRKITTYAADDGQEISDLR
WTPDSSAIVYVRGGSANPALDPAGVTQAIWRAALDGTAARKIGEGNAPAVSPKGDKVVFIRAGQLWWAPLDGKAEASQVF
QARGACDRPRWSPDGARISFTSARGDHGFIGVFDVAAGALRYLDPSTDNDSEPEWSPDGRSVAFLRVPSSGVRMPREPHR
TGEPWSIRIADAHTGAGREVFHAREGAGSVFRGVNARNQILWADGNRLVFPWEPEGWTHLYAVSTEGGKATLLTPGKFEV
EDVAVSGKQVLYSSNQDDIDRRHLWKVAADGGVPTAITSGQGIECQPAPTSDPNVITFLRSDAQRPLRAAVSVAGAARDL
DPGAIPSDFPTSLATPQQVVFPAGDGLAIHGQLFLPTKKPTDGRSPAIVFFHGGSRRQMLLGWHYMYYYANAYAMNQYLA
SLGYVVLSVNYRSGIGYGSDFREAVNYGANGGTEYNDVQGAGIYLQGRTDVDGGRIGVWGGSYGGYLTAMALARASDMYK
VGVDFHGVHNWATELGIPVTAPDYKIAFESSPMNFLKTWQSPVLLIQGDDDPDVQFNQTVMLADALRKQGVEIEEMVIPD
EVHDFLLHRSWLTTYKATAEFLRRHLK
>Mature_667_residues
MRLIALCALALTASAQPSLDRLLSAAFPSELTAAPAGGKVAWVSNAKGLRNIMVAEPPAYVGRKITTYAADDGQEISDLR
WTPDSSAIVYVRGGSANPALDPAGVTQAIWRAALDGTAARKIGEGNAPAVSPKGDKVVFIRAGQLWWAPLDGKAEASQVF
QARGACDRPRWSPDGARISFTSARGDHGFIGVFDVAAGALRYLDPSTDNDSEPEWSPDGRSVAFLRVPSSGVRMPREPHR
TGEPWSIRIADAHTGAGREVFHAREGAGSVFRGVNARNQILWADGNRLVFPWEPEGWTHLYAVSTEGGKATLLTPGKFEV
EDVAVSGKQVLYSSNQDDIDRRHLWKVAADGGVPTAITSGQGIECQPAPTSDPNVITFLRSDAQRPLRAAVSVAGAARDL
DPGAIPSDFPTSLATPQQVVFPAGDGLAIHGQLFLPTKKPTDGRSPAIVFFHGGSRRQMLLGWHYMYYYANAYAMNQYLA
SLGYVVLSVNYRSGIGYGSDFREAVNYGANGGTEYNDVQGAGIYLQGRTDVDGGRIGVWGGSYGGYLTAMALARASDMYK
VGVDFHGVHNWATELGIPVTAPDYKIAFESSPMNFLKTWQSPVLLIQGDDDPDVQFNQTVMLADALRKQGVEIEEMVIPD
EVHDFLLHRSWLTTYKATAEFLRRHLK

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=260, Percent_Identity=25, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI37577089, Length=338, Percent_Identity=25.7396449704142, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI18450280, Length=338, Percent_Identity=25.7396449704142, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI18765694, Length=393, Percent_Identity=23.6641221374046, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25144540, Length=288, Percent_Identity=25.6944444444444, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25144537, Length=285, Percent_Identity=25.6140350877193, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17552908, Length=201, Percent_Identity=25.3731343283582, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582257, Length=248, Percent_Identity=29.8387096774194, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582032, Length=123, Percent_Identity=34.9593495934959, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 72024; Mature: 72024

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIALCALALTASAQPSLDRLLSAAFPSELTAAPAGGKVAWVSNAKGLRNIMVAEPPAY
CHHHHEEHHHHHCCCCCCHHHHHHHHCCCHHCCCCCCCEEEEECCCCCCCEEEEECCCHH
VGRKITTYAADDGQEISDLRWTPDSSAIVYVRGGSANPALDPAGVTQAIWRAALDGTAAR
HCCEEEEEECCCCCCCCCCEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHH
KIGEGNAPAVSPKGDKVVFIRAGQLWWAPLDGKAEASQVFQARGACDRPRWSPDGARISF
HCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEE
TSARGDHGFIGVFDVAAGALRYLDPSTDNDSEPEWSPDGRSVAFLRVPSSGVRMPREPHR
EECCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
TGEPWSIRIADAHTGAGREVFHAREGAGSVFRGVNARNQILWADGNRLVFPWEPEGWTHL
CCCCEEEEEEECCCCCCCHHEECCCCCCHHHHCCCCCCEEEEECCCEEEEECCCCCCEEE
YAVSTEGGKATLLTPGKFEVEDVAVSGKQVLYSSNQDDIDRRHLWKVAADGGVPTAITSG
EEEECCCCEEEEECCCCEEEEEEEECCCEEEECCCCCCCCHHHEEEEECCCCCCEEEECC
QGIECQPAPTSDPNVITFLRSDAQRPLRAAVSVAGAARDLDPGAIPSDFPTSLATPQQVV
CCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
FPAGDGLAIHGQLFLPTKKPTDGRSPAIVFFHGGSRRQMLLGWHYMYYYANAYAMNQYLA
EECCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEHHHHHHHHHHHHH
SLGYVVLSVNYRSGIGYGSDFREAVNYGANGGTEYNDVQGAGIYLQGRTDVDGGRIGVWG
HCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECC
GSYGGYLTAMALARASDMYKVGVDFHGVHNWATELGIPVTAPDYKIAFESSPMNFLKTWQ
CCCCHHHHHHHHHHHCCEEEECCEEECHHHHHHHCCCCCCCCCEEEEECCCCHHHHHCCC
SPVLLIQGDDDPDVQFNQTVMLADALRKQGVEIEEMVIPDEVHDFLLHRSWLTTYKATAE
CCEEEEECCCCCCCEECCEEHHHHHHHHCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHH
FLRRHLK
HHHHHCC
>Mature Secondary Structure
MRLIALCALALTASAQPSLDRLLSAAFPSELTAAPAGGKVAWVSNAKGLRNIMVAEPPAY
CHHHHEEHHHHHCCCCCCHHHHHHHHCCCHHCCCCCCCEEEEECCCCCCCEEEEECCCHH
VGRKITTYAADDGQEISDLRWTPDSSAIVYVRGGSANPALDPAGVTQAIWRAALDGTAAR
HCCEEEEEECCCCCCCCCCEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHH
KIGEGNAPAVSPKGDKVVFIRAGQLWWAPLDGKAEASQVFQARGACDRPRWSPDGARISF
HCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEE
TSARGDHGFIGVFDVAAGALRYLDPSTDNDSEPEWSPDGRSVAFLRVPSSGVRMPREPHR
EECCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
TGEPWSIRIADAHTGAGREVFHAREGAGSVFRGVNARNQILWADGNRLVFPWEPEGWTHL
CCCCEEEEEEECCCCCCCHHEECCCCCCHHHHCCCCCCEEEEECCCEEEEECCCCCCEEE
YAVSTEGGKATLLTPGKFEVEDVAVSGKQVLYSSNQDDIDRRHLWKVAADGGVPTAITSG
EEEECCCCEEEEECCCCEEEEEEEECCCEEEECCCCCCCCHHHEEEEECCCCCCEEEECC
QGIECQPAPTSDPNVITFLRSDAQRPLRAAVSVAGAARDLDPGAIPSDFPTSLATPQQVV
CCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
FPAGDGLAIHGQLFLPTKKPTDGRSPAIVFFHGGSRRQMLLGWHYMYYYANAYAMNQYLA
EECCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEHHHHHHHHHHHHH
SLGYVVLSVNYRSGIGYGSDFREAVNYGANGGTEYNDVQGAGIYLQGRTDVDGGRIGVWG
HCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECC
GSYGGYLTAMALARASDMYKVGVDFHGVHNWATELGIPVTAPDYKIAFESSPMNFLKTWQ
CCCCHHHHHHHHHHHCCEEEECCEEECHHHHHHHCCCCCCCCCEEEEECCCCHHHHHCCC
SPVLLIQGDDDPDVQFNQTVMLADALRKQGVEIEEMVIPDEVHDFLLHRSWLTTYKATAE
CCEEEEECCCCCCCEECCEEHHHHHHHHCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHH
FLRRHLK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]