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The map label for this gene is arnC [H]

Identifier: 116620921

GI number: 116620921

Start: 2241612

End: 2242337

Strand: Reverse

Name: arnC [H]

Synonym: Acid_1802

Alternate gene names: 116620921

Gene position: 2242337-2241612 (Counterclockwise)

Preceding gene: 116620922

Following gene: 116620920

Centisome position: 22.5

GC content: 61.02

Gene sequence:

>726_bases
GTGAACGGGCGCTTCCCTTCCCTGAGCGTCTTCTTCCCGGCGTATAACGACGCGCCGTCGCTGCCGGGCCTGCTGGCGAA
GACGTTCCATGCGCTCGAGGAGCACGTCGCGGATTACGAAGTCATCGTGGTCAACGACGGCAGCTACGACGATACCGGGA
AAGTGCTGGAAGAGTTGCGCCAGAAGTATCATCCGTACCTCCGCGTGGTCACGCACGAGCAGAATCGCGGCTATGGCGGC
GCGCTGCGCACCGGCTTCGAGAGTGCCACACGGGAATTCGTTTTCTACACAGACGGCGACGGCCAATACGACGCGGGGGA
ATTGCCGAAGCTCCTGGAGTTAATGACGCCCGATACCGGACTGGTGAACGGCTACAAGCTGGAGCGCCACGATCCGGCGC
ACCGCATCTGGATCGGCAGCACCTACAACTTCTGCGCGCGGCTCCTGTTCGGAATCAGGATCCGCGACATCGATTGTGAC
TTCCGCCTCATCCGAAAGTCGCGGCTGCAGGAGATCCGGCTGACGTCAACCAGCGGCACGATCTGCGTGGAGCTGGTGCG
AAAGCTCGAATTGACCGGCTGCGGCGTGGTGGAGACGGGCGTCCGTCATTACCCGCGCCTGCATGGAAAATCGCAGTTTT
TCCGGCTCAAATCGCTGGCAACCACGTTGGGCGAGTTGATCCGCCTCTGGGTGCGAGTGGTGCTGTTAAGAGGAAAGAAG
TACTAA

Upstream 100 bases:

>100_bases
GCCTGCTTTACGCGCCGCTGGCGATGGAGGCGTCGTGGGTCGGCGGCGGACGAAGCTTCCCCATCGGCCAGTCGCTGGTA
TTCATCGGTGAGAGGATGTT

Downstream 100 bases:

>100_bases
TTTCTGCCTATTGCAATCTGCAAATCACTCAAACATGAAATTTATCTTCGCGTTGTTATCAGCAACTTAGAAGTTATACC
TACCCTATACTCCTTTACTC

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNGRFPSLSVFFPAYNDAPSLPGLLAKTFHALEEHVADYEVIVVNDGSYDDTGKVLEELRQKYHPYLRVVTHEQNRGYGG
ALRTGFESATREFVFYTDGDGQYDAGELPKLLELMTPDTGLVNGYKLERHDPAHRIWIGSTYNFCARLLFGIRIRDIDCD
FRLIRKSRLQEIRLTSTSGTICVELVRKLELTGCGVVETGVRHYPRLHGKSQFFRLKSLATTLGELIRLWVRVVLLRGKK
Y

Sequences:

>Translated_241_residues
MNGRFPSLSVFFPAYNDAPSLPGLLAKTFHALEEHVADYEVIVVNDGSYDDTGKVLEELRQKYHPYLRVVTHEQNRGYGG
ALRTGFESATREFVFYTDGDGQYDAGELPKLLELMTPDTGLVNGYKLERHDPAHRIWIGSTYNFCARLLFGIRIRDIDCD
FRLIRKSRLQEIRLTSTSGTICVELVRKLELTGCGVVETGVRHYPRLHGKSQFFRLKSLATTLGELIRLWVRVVLLRGKK
Y
>Mature_241_residues
MNGRFPSLSVFFPAYNDAPSLPGLLAKTFHALEEHVADYEVIVVNDGSYDDTGKVLEELRQKYHPYLRVVTHEQNRGYGG
ALRTGFESATREFVFYTDGDGQYDAGELPKLLELMTPDTGLVNGYKLERHDPAHRIWIGSTYNFCARLLFGIRIRDIDCD
FRLIRKSRLQEIRLTSTSGTICVELVRKLELTGCGVVETGVRHYPRLHGKSQFFRLKSLATTLGELIRLWVRVVLLRGKK
Y

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI7019323, Length=175, Percent_Identity=34.2857142857143, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1788588, Length=214, Percent_Identity=25.7009345794392, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787259, Length=122, Percent_Identity=35.2459016393443, Blast_Score=72, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582769, Length=246, Percent_Identity=31.3008130081301, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 27531; Mature: 27531

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGRFPSLSVFFPAYNDAPSLPGLLAKTFHALEEHVADYEVIVVNDGSYDDTGKVLEELR
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHH
QKYHPYLRVVTHEQNRGYGGALRTGFESATREFVFYTDGDGQYDAGELPKLLELMTPDTG
HHHCCEEEEEEECCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCCC
LVNGYKLERHDPAHRIWIGSTYNFCARLLFGIRIRDIDCDFRLIRKSRLQEIRLTSTSGT
CCCCEEECCCCCCCEEEECCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHEEEECCCCH
ICVELVRKLELTGCGVVETGVRHYPRLHGKSQFFRLKSLATTLGELIRLWVRVVLLRGKK
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
Y
C
>Mature Secondary Structure
MNGRFPSLSVFFPAYNDAPSLPGLLAKTFHALEEHVADYEVIVVNDGSYDDTGKVLEELR
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHH
QKYHPYLRVVTHEQNRGYGGALRTGFESATREFVFYTDGDGQYDAGELPKLLELMTPDTG
HHHCCEEEEEEECCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCCC
LVNGYKLERHDPAHRIWIGSTYNFCARLLFGIRIRDIDCDFRLIRKSRLQEIRLTSTSGT
CCCCEEECCCCCCCEEEECCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHEEEECCCCH
ICVELVRKLELTGCGVVETGVRHYPRLHGKSQFFRLKSLATTLGELIRLWVRVVLLRGKK
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA