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The map label for this gene is ynaI [C]

Identifier: 116620896

GI number: 116620896

Start: 2211792

End: 2213399

Strand: Reverse

Name: ynaI [C]

Synonym: Acid_1777

Alternate gene names: 116620896

Gene position: 2213399-2211792 (Counterclockwise)

Preceding gene: 116620899

Following gene: 116620894

Centisome position: 22.21

GC content: 64.61

Gene sequence:

>1608_bases
ATGAAGCTGCGAGCGTGCCTGACGGGGCTGTTGCTTTGCGCGCGGCTGGGCGCACAGCTCACGCTATCCGCGCCGGCTCC
CGCCGCGGCGCCGGTAGAAGCGCCGAAGGACGCGCTCGGCCGCACCACCCCGCGCGGCACCGTGAAGGGTTTTCTGGAGG
CAGGACACAAAGGGAACCTGCAAGTGGCGGCGCAGTACCTGAATACGCGATTGCGCGGCGCGCACGCAGAACGCCTGGCC
GAGCAGTTGTTCAGCGTTCTGAATCGACGCCTTCCGGCCAGGCTGATGGAACTGAGCGACAAGCCGGAGGGCTCGCTGAC
AGACCTCAAGGGCGATCAGGACCTGGTAGGCACAATTGCCAGTGCGCAGGGCGACCTGGAGATCGTTGTGGAACGCGTCT
CACGCGGCAAGGAGGCGCCGCTCTGGCTGTTCTCTTCACAGACCCTGGAAAAAATTCCCGCGCTGTTCGACGAGGTCAAT
GCCGTACCGATCGACAGTCTTCTACCGCCGATCCTGGTGAAGACCACGGTCGGTGGGATCGCACTGTTCGAGTGGCTTGG
CCTCCTGGTGGGCCTGCCCGCCGCCTACCTGGTCACGGTTCTGCTGAACCGGGCGCTGAGCGGGCTGGCCGGTGCCGTGC
GCCGCCGTCTGAGGAAGGATCCAGGTCTGCCTGATCCTGAAATTCTGCCGGCGCCGATTCGCCTGCTCATGGTGGCAGCG
GCCATTTCCTGGGTGCGCTCCGCCGTATTCCTGCCGTTGCTGGCTCGCCAATTCTGGACCAGCGTGGCCAGCGTCCTCAC
CATCGCCGCAGTGGCGTGGCTGATCATCGTCTTCAACGGCGGGTTGGAGCAGTGGCTGCGCCGCCGCCTGCTGCGCGCCG
GATGCGTGGGAGCGACTTCCGTAATCCGCCTGGGCCGACGCATGCTGGACGTGCTGATTGTATTCATCGGGCTGCTTGTG
GCCTTCTATCACTTCGGCTGGAATCCCACGGCGGCACTGGCCGGGCTGGGCGTCGGCGGCGTTGCGGTGGCTCTCGCAGC
CCAGCGGACCCTGGAGAATGTGATCGGCGGAATCTCGATCATTTTCGACCAGGTAGTGCGGGTAGGCGATACGCTCCGGG
TCGGCGAGACCAGCGGCATCGTCGATGATGTCGGGTTGCGTTCCACCAGGCTGCGGACGAATGACCGCACCGTGGTGAGC
GTCCCGAATGGACAGATCGCCAACCTGAGTCTCGAGAACCTTTCCGCGCGCGATAAGTTCTGGCTTCATCCCACCGTCAG
TCTGCGCTGTGACACCACCGTGGAGCAACTGCGAAGTGTCGTGGAGGGGCTGCACGACCTGCTGGCGCGGGATCTCCGCG
TGGAGCAGGACAGCGTTCGGGTGCGATTCCTGCGGCTGGGTCCGAACTCGCTCGACGTAGAAGTCTTCGCGTACGTGAGG
GCGAAGGAGTGGAATCACTTCCTCGACATTCAAGGAGAGATCCTGCTGGGTTGCATGGAGTGCGTGCAGACCGCGGGGGC
GCGGCTCGCGATTCCATCCGCGCTTTACCTGGAGGCCGTTGGGAAGGCGGAGTTGGACTTGATGCATCCGACGCCAACTC
CGCGGTAA

Upstream 100 bases:

>100_bases
GGCGCGGGTTAGTTTTTGCGGCGGCGGCGCGTGGCAACCCCTTTTTCTACATCGCTTTTGCGCGCTCAACGATCCCAAGT
AATTGGTGAGTGTACACGCC

Downstream 100 bases:

>100_bases
GGCTGCGGGTGCGCTCTGCCGGGGCGAATCCGGCTGAAAGCCGGCTGCAGGCAGGATTGCCTGCCCCACTAGCCTAGAAC
GTCATGCGGAGGCCGAGTTG

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MKLRACLTGLLLCARLGAQLTLSAPAPAAAPVEAPKDALGRTTPRGTVKGFLEAGHKGNLQVAAQYLNTRLRGAHAERLA
EQLFSVLNRRLPARLMELSDKPEGSLTDLKGDQDLVGTIASAQGDLEIVVERVSRGKEAPLWLFSSQTLEKIPALFDEVN
AVPIDSLLPPILVKTTVGGIALFEWLGLLVGLPAAYLVTVLLNRALSGLAGAVRRRLRKDPGLPDPEILPAPIRLLMVAA
AISWVRSAVFLPLLARQFWTSVASVLTIAAVAWLIIVFNGGLEQWLRRRLLRAGCVGATSVIRLGRRMLDVLIVFIGLLV
AFYHFGWNPTAALAGLGVGGVAVALAAQRTLENVIGGISIIFDQVVRVGDTLRVGETSGIVDDVGLRSTRLRTNDRTVVS
VPNGQIANLSLENLSARDKFWLHPTVSLRCDTTVEQLRSVVEGLHDLLARDLRVEQDSVRVRFLRLGPNSLDVEVFAYVR
AKEWNHFLDIQGEILLGCMECVQTAGARLAIPSALYLEAVGKAELDLMHPTPTPR

Sequences:

>Translated_535_residues
MKLRACLTGLLLCARLGAQLTLSAPAPAAAPVEAPKDALGRTTPRGTVKGFLEAGHKGNLQVAAQYLNTRLRGAHAERLA
EQLFSVLNRRLPARLMELSDKPEGSLTDLKGDQDLVGTIASAQGDLEIVVERVSRGKEAPLWLFSSQTLEKIPALFDEVN
AVPIDSLLPPILVKTTVGGIALFEWLGLLVGLPAAYLVTVLLNRALSGLAGAVRRRLRKDPGLPDPEILPAPIRLLMVAA
AISWVRSAVFLPLLARQFWTSVASVLTIAAVAWLIIVFNGGLEQWLRRRLLRAGCVGATSVIRLGRRMLDVLIVFIGLLV
AFYHFGWNPTAALAGLGVGGVAVALAAQRTLENVIGGISIIFDQVVRVGDTLRVGETSGIVDDVGLRSTRLRTNDRTVVS
VPNGQIANLSLENLSARDKFWLHPTVSLRCDTTVEQLRSVVEGLHDLLARDLRVEQDSVRVRFLRLGPNSLDVEVFAYVR
AKEWNHFLDIQGEILLGCMECVQTAGARLAIPSALYLEAVGKAELDLMHPTPTPR
>Mature_535_residues
MKLRACLTGLLLCARLGAQLTLSAPAPAAAPVEAPKDALGRTTPRGTVKGFLEAGHKGNLQVAAQYLNTRLRGAHAERLA
EQLFSVLNRRLPARLMELSDKPEGSLTDLKGDQDLVGTIASAQGDLEIVVERVSRGKEAPLWLFSSQTLEKIPALFDEVN
AVPIDSLLPPILVKTTVGGIALFEWLGLLVGLPAAYLVTVLLNRALSGLAGAVRRRLRKDPGLPDPEILPAPIRLLMVAA
AISWVRSAVFLPLLARQFWTSVASVLTIAAVAWLIIVFNGGLEQWLRRRLLRAGCVGATSVIRLGRRMLDVLIVFIGLLV
AFYHFGWNPTAALAGLGVGGVAVALAAQRTLENVIGGISIIFDQVVRVGDTLRVGETSGIVDDVGLRSTRLRTNDRTVVS
VPNGQIANLSLENLSARDKFWLHPTVSLRCDTTVEQLRSVVEGLHDLLARDLRVEQDSVRVRFLRLGPNSLDVEVFAYVR
AKEWNHFLDIQGEILLGCMECVQTAGARLAIPSALYLEAVGKAELDLMHPTPTPR

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=226, Percent_Identity=27.4336283185841, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789291, Length=184, Percent_Identity=26.6304347826087, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 57929; Mature: 57929

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS01246 UPF0003

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRACLTGLLLCARLGAQLTLSAPAPAAAPVEAPKDALGRTTPRGTVKGFLEAGHKGNL
CCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCCCH
QVAAQYLNTRLRGAHAERLAEQLFSVLNRRLPARLMELSDKPEGSLTDLKGDQDLVGTIA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
SAQGDLEIVVERVSRGKEAPLWLFSSQTLEKIPALFDEVNAVPIDSLLPPILVKTTVGGI
CCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHH
ALFEWLGLLVGLPAAYLVTVLLNRALSGLAGAVRRRLRKDPGLPDPEILPAPIRLLMVAA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AISWVRSAVFLPLLARQFWTSVASVLTIAAVAWLIIVFNGGLEQWLRRRLLRAGCVGATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHH
VIRLGRRMLDVLIVFIGLLVAFYHFGWNPTAALAGLGVGGVAVALAAQRTLENVIGGISI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IFDQVVRVGDTLRVGETSGIVDDVGLRSTRLRTNDRTVVSVPNGQIANLSLENLSARDKF
HHHHHHHHCCCEEECCCCCCHHHCCCCCCEEECCCCEEEECCCCCEEEEEHHCCCCCCCE
WLHPTVSLRCDTTVEQLRSVVEGLHDLLARDLRVEQDSVRVRFLRLGPNSLDVEVFAYVR
EECCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEH
AKEWNHFLDIQGEILLGCMECVQTAGARLAIPSALYLEAVGKAELDLMHPTPTPR
HHCCCCEECCCHHHHHHHHHHHHHCCCCEECCHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MKLRACLTGLLLCARLGAQLTLSAPAPAAAPVEAPKDALGRTTPRGTVKGFLEAGHKGNL
CCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCCCH
QVAAQYLNTRLRGAHAERLAEQLFSVLNRRLPARLMELSDKPEGSLTDLKGDQDLVGTIA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
SAQGDLEIVVERVSRGKEAPLWLFSSQTLEKIPALFDEVNAVPIDSLLPPILVKTTVGGI
CCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHH
ALFEWLGLLVGLPAAYLVTVLLNRALSGLAGAVRRRLRKDPGLPDPEILPAPIRLLMVAA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AISWVRSAVFLPLLARQFWTSVASVLTIAAVAWLIIVFNGGLEQWLRRRLLRAGCVGATS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHH
VIRLGRRMLDVLIVFIGLLVAFYHFGWNPTAALAGLGVGGVAVALAAQRTLENVIGGISI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IFDQVVRVGDTLRVGETSGIVDDVGLRSTRLRTNDRTVVSVPNGQIANLSLENLSARDKF
HHHHHHHHCCCEEECCCCCCHHHCCCCCCEEECCCCEEEECCCCCEEEEEHHCCCCCCCE
WLHPTVSLRCDTTVEQLRSVVEGLHDLLARDLRVEQDSVRVRFLRLGPNSLDVEVFAYVR
EECCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEH
AKEWNHFLDIQGEILLGCMECVQTAGARLAIPSALYLEAVGKAELDLMHPTPTPR
HHCCCCEECCCHHHHHHHHHHHHHCCCCEECCHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]