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The map label for this gene is hicB2 [H]

Identifier: 116620833

GI number: 116620833

Start: 2131670

End: 2132146

Strand: Direct

Name: hicB2 [H]

Synonym: Acid_1714

Alternate gene names: 116620833

Gene position: 2131670-2132146 (Clockwise)

Preceding gene: 116620831

Following gene: 116620834

Centisome position: 21.39

GC content: 58.07

Gene sequence:

>477_bases
ATGTTAAAGCAACTCGGAATTCGCAATGAGGACCTAATAATGTTTACCGCGACCTATCCTGCCAATTTTCTACGCGAGAA
GAACCGCAAGGGCTTCCACGTCCGCTTTCCCGATTTGCCCGAAGCTCTCACTGGAGGAGTGGATCTCGACGACACGCGCG
AGGAGGCAGTCGATTGTTTGGCCGAAGCTCTCGCCGGGCGGATCGCACGAGGGGATCTGATCCCGGCCCCTTCCAAGTTG
AGACGAGGCCAACATCCGGTAAGCGTTCCGCTCCTCCTGGCACCCAAGCTTGCCCTTTATCTGGCCATGCGCGAGGGAGG
CATTCGGAATACGGAGTTGGCGAGACGTCTCGGCGTCAGCGAAACCGTTGTCCGCCGGATGCTGGACCCGAAGCACAACA
CCAAGCCTGAGAAGATCCAAGCCGCTCTGGGAGTTCTCGGCAAACGGATTGTCATCACCTTCGAGGATGCGGCGTAG

Upstream 100 bases:

>100_bases
GGAGCGCGGCTCCGGCAGCCACGGCACCCTCTACGTGGGCGACAGTTTCACGATTGTAAAGGACCTCAAGAAAGAACTTG
GTCCCGCCTTGTTGTCCGAC

Downstream 100 bases:

>100_bases
CGGTCACGCTGCTCATGTCCCGGCGAATGCTCTTGAAGGCCAGCGGTGCCCCCATCGCAATCTACTCTCGCGTCCTTATC
CCCGGCCCAGCCCAAGTTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MLKQLGIRNEDLIMFTATYPANFLREKNRKGFHVRFPDLPEALTGGVDLDDTREEAVDCLAEALAGRIARGDLIPAPSKL
RRGQHPVSVPLLLAPKLALYLAMREGGIRNTELARRLGVSETVVRRMLDPKHNTKPEKIQAALGVLGKRIVITFEDAA

Sequences:

>Translated_158_residues
MLKQLGIRNEDLIMFTATYPANFLREKNRKGFHVRFPDLPEALTGGVDLDDTREEAVDCLAEALAGRIARGDLIPAPSKL
RRGQHPVSVPLLLAPKLALYLAMREGGIRNTELARRLGVSETVVRRMLDPKHNTKPEKIQAALGVLGKRIVITFEDAA
>Mature_158_residues
MLKQLGIRNEDLIMFTATYPANFLREKNRKGFHVRFPDLPEALTGGVDLDDTREEAVDCLAEALAGRIARGDLIPAPSKL
RRGQHPVSVPLLLAPKLALYLAMREGGIRNTELARRLGVSETVVRRMLDPKHNTKPEKIQAALGVLGKRIVITFEDAA

Specific function: Part of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin preventing effects of the HicA 2 toxin [H]

COG id: COG1598

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693129, Length=120, Percent_Identity=37.5, Blast_Score=77, Evalue=4e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005357 [H]

Pfam domain/function: PF03681 UPF0150 [H]

EC number: NA

Molecular weight: Translated: 17504; Mature: 17504

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQLGIRNEDLIMFTATYPANFLREKNRKGFHVRFPDLPEALTGGVDLDDTREEAVDCL
CCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCEEECCCCHHHHHCCCCCCCCHHHHHHHH
AEALAGRIARGDLIPAPSKLRRGQHPVSVPLLLAPKLALYLAMREGGIRNTELARRLGVS
HHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCH
ETVVRRMLDPKHNTKPEKIQAALGVLGKRIVITFEDAA
HHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCC
>Mature Secondary Structure
MLKQLGIRNEDLIMFTATYPANFLREKNRKGFHVRFPDLPEALTGGVDLDDTREEAVDCL
CCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCEEECCCCHHHHHCCCCCCCCHHHHHHHH
AEALAGRIARGDLIPAPSKLRRGQHPVSVPLLLAPKLALYLAMREGGIRNTELARRLGVS
HHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCH
ETVVRRMLDPKHNTKPEKIQAALGVLGKRIVITFEDAA
HHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]