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The map label for this gene is tolC [C]

Identifier: 116620785

GI number: 116620785

Start: 2067029

End: 2068309

Strand: Reverse

Name: tolC [C]

Synonym: Acid_1666

Alternate gene names: 116620785

Gene position: 2068309-2067029 (Counterclockwise)

Preceding gene: 116620786

Following gene: 116620783

Centisome position: 20.75

GC content: 65.18

Gene sequence:

>1281_bases
ATGGTGCATCGTGCAATCATCCTCAGCATTGCCCTCGCCGCCCCGTTGACCGCCGAAGTTCATCCTATGACTCTGCGGCA
GGCCGTAGCGCGTGCCATCCAGCAGAATCCCGACGTCACGCTGGCACGCCTGGAAGAAGAGAACGCGCGCCACGCCGTGG
GTGTCGCCAAGGACCCGTTCTCGCCGCGCGTGACCGTGGGCAGCGGCCTCGCCTACAGCAACGGCTTTCCCCTCTCGGCC
CCCAGTATCGTGCAGGCGCACGCCACGCAATATATCTTCAACCGGCAGCAGAGCTATACTGTGGCGGCGGCCAAGGAGCA
GGTGCGCGGCGCCGGTTTCGTGGTTTCCAGCAAGCGCGACGAGGTAGCGTACCGCACCGCCTCCCTCTACCTGGACGCGG
AGCGTGCCGCGCGCGTGCTGGCTCTCTCCCGCAAGGATGCCGAGAGCCAGCAGAAAGTGCTCGATACCATTCAGGCGCAG
GTCGGCGAGGGCCGCGCGCTGCCCCTGGCGGAGAAGCAGGCCGCCTACAACCTGGCGCGGTCACGCCAGGTCGCCGACTC
CCTGGACGCCGATCGCGAGTACGCGGAGACCGCACTCGCCATCGCCGCGGGATTCTCCGCCGACGACCGCGTGCGTCCCG
TGGAAGAACAGCGAACCGCGCCGCCACTCCCGGCATCGGAGGAGCACGCCGTGCAATCGGCCCTCGATTCCAACAAGGAT
TTGCGCAAACTGCAATCGCAGATCACCGCCAAAGGGCTGGAGGCGCGCAGCGAGAGGGCCGCCCGGCTGCCGCGCCTCGA
CCTGGTGGCGCAATACGCGTTGTTCGCGAAATTCAACAACTATGAGGATTACTACCGGAGCTTCCAGCGCAACAACGGCC
AAATCGGCATCTCCTTCCAGGTGCCGGTGTTCAGCGGTCCCGGAGTCGGCGAGCAACTTGCGCAGACGCAAACCGAGATT
TCACACCTGAAGGTGGAACTGAGCAGCGCGCGCAATCGCATCAGCGCGGATTTGCAGCAATCCTTTCGCGACGTCCACAA
GGCGGAGATGTCGGCGGAGGTCGCGCGGCTCGATCTCGAGGTCGCGCGCGAGCAGCTTTCGGTCAACCTGGCGCAGATGC
AAGAAGGCCGCCTCGGAATGCGCCAGGTGGAAGAGTCGCGGATGGTGGAGAACGCCAAGTGGATCGCCTTCTACGAAGCA
CAGTATGTGGTGGAAAAGGCGCGGTGGAACGTGCTCCGCCTGACCGGCGACCTGGTGCCGGCGATCGAATCCATGCCGTA
G

Upstream 100 bases:

>100_bases
CGACCACTCAGCCACCTCTCCGTGAGATGAAAATGGTCTGTAAAAGAATCGTACCACATCGTCACTCGCTCCTCTCGGAA
TCGCTGCTTACAATCAAGGG

Downstream 100 bases:

>100_bases
GCGCCCAATAAAAAAGCTCCCGGACGAGTGAAGTTCACCGTCCGGGAGCGTTGCGATTCTCCCATTTCCAAATGGAGCGA
AAGTCTAGCTGCAGCCGCTG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation Efflux System Protein

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MVHRAIILSIALAAPLTAEVHPMTLRQAVARAIQQNPDVTLARLEEENARHAVGVAKDPFSPRVTVGSGLAYSNGFPLSA
PSIVQAHATQYIFNRQQSYTVAAAKEQVRGAGFVVSSKRDEVAYRTASLYLDAERAARVLALSRKDAESQQKVLDTIQAQ
VGEGRALPLAEKQAAYNLARSRQVADSLDADREYAETALAIAAGFSADDRVRPVEEQRTAPPLPASEEHAVQSALDSNKD
LRKLQSQITAKGLEARSERAARLPRLDLVAQYALFAKFNNYEDYYRSFQRNNGQIGISFQVPVFSGPGVGEQLAQTQTEI
SHLKVELSSARNRISADLQQSFRDVHKAEMSAEVARLDLEVAREQLSVNLAQMQEGRLGMRQVEESRMVENAKWIAFYEA
QYVVEKARWNVLRLTGDLVPAIESMP

Sequences:

>Translated_426_residues
MVHRAIILSIALAAPLTAEVHPMTLRQAVARAIQQNPDVTLARLEEENARHAVGVAKDPFSPRVTVGSGLAYSNGFPLSA
PSIVQAHATQYIFNRQQSYTVAAAKEQVRGAGFVVSSKRDEVAYRTASLYLDAERAARVLALSRKDAESQQKVLDTIQAQ
VGEGRALPLAEKQAAYNLARSRQVADSLDADREYAETALAIAAGFSADDRVRPVEEQRTAPPLPASEEHAVQSALDSNKD
LRKLQSQITAKGLEARSERAARLPRLDLVAQYALFAKFNNYEDYYRSFQRNNGQIGISFQVPVFSGPGVGEQLAQTQTEI
SHLKVELSSARNRISADLQQSFRDVHKAEMSAEVARLDLEVAREQLSVNLAQMQEGRLGMRQVEESRMVENAKWIAFYEA
QYVVEKARWNVLRLTGDLVPAIESMP
>Mature_426_residues
MVHRAIILSIALAAPLTAEVHPMTLRQAVARAIQQNPDVTLARLEEENARHAVGVAKDPFSPRVTVGSGLAYSNGFPLSA
PSIVQAHATQYIFNRQQSYTVAAAKEQVRGAGFVVSSKRDEVAYRTASLYLDAERAARVLALSRKDAESQQKVLDTIQAQ
VGEGRALPLAEKQAAYNLARSRQVADSLDADREYAETALAIAAGFSADDRVRPVEEQRTAPPLPASEEHAVQSALDSNKD
LRKLQSQITAKGLEARSERAARLPRLDLVAQYALFAKFNNYEDYYRSFQRNNGQIGISFQVPVFSGPGVGEQLAQTQTEI
SHLKVELSSARNRISADLQQSFRDVHKAEMSAEVARLDLEVAREQLSVNLAQMQEGRLGMRQVEESRMVENAKWIAFYEA
QYVVEKARWNVLRLTGDLVPAIESMP

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47055; Mature: 47055

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHRAIILSIALAAPLTAEVHPMTLRQAVARAIQQNPDVTLARLEEENARHAVGVAKDPF
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
SPRVTVGSGLAYSNGFPLSAPSIVQAHATQYIFNRQQSYTVAAAKEQVRGAGFVVSSKRD
CCCEEECCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCEEEECCCC
EVAYRTASLYLDAERAARVLALSRKDAESQQKVLDTIQAQVGEGRALPLAEKQAAYNLAR
HHHHHHHHHEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
SRQVADSLDADREYAETALAIAAGFSADDRVRPVEEQRTAPPLPASEEHAVQSALDSNKD
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCHH
LRKLQSQITAKGLEARSERAARLPRLDLVAQYALFAKFNNYEDYYRSFQRNNGQIGISFQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEE
VPVFSGPGVGEQLAQTQTEISHLKVELSSARNRISADLQQSFRDVHKAEMSAEVARLDLE
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAREQLSVNLAQMQEGRLGMRQVEESRMVENAKWIAFYEAQYVVEKARWNVLRLTGDLVP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCEEEECCCHHH
AIESMP
HHHCCC
>Mature Secondary Structure
MVHRAIILSIALAAPLTAEVHPMTLRQAVARAIQQNPDVTLARLEEENARHAVGVAKDPF
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCC
SPRVTVGSGLAYSNGFPLSAPSIVQAHATQYIFNRQQSYTVAAAKEQVRGAGFVVSSKRD
CCCEEECCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCEEEECCCC
EVAYRTASLYLDAERAARVLALSRKDAESQQKVLDTIQAQVGEGRALPLAEKQAAYNLAR
HHHHHHHHHEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
SRQVADSLDADREYAETALAIAAGFSADDRVRPVEEQRTAPPLPASEEHAVQSALDSNKD
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCHH
LRKLQSQITAKGLEARSERAARLPRLDLVAQYALFAKFNNYEDYYRSFQRNNGQIGISFQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEE
VPVFSGPGVGEQLAQTQTEISHLKVELSSARNRISADLQQSFRDVHKAEMSAEVARLDLE
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAREQLSVNLAQMQEGRLGMRQVEESRMVENAKWIAFYEAQYVVEKARWNVLRLTGDLVP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCEEEECCCHHH
AIESMP
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA