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The map label for this gene is macB [H]

Identifier: 116620774

GI number: 116620774

Start: 2051168

End: 2052331

Strand: Direct

Name: macB [H]

Synonym: Acid_1655

Alternate gene names: 116620774

Gene position: 2051168-2052331 (Clockwise)

Preceding gene: 116620773

Following gene: 116620775

Centisome position: 20.58

GC content: 61.94

Gene sequence:

>1164_bases
ATGGCCATCCCCGTAGCCTACAACCTGCGAAACCTCGTGGTTCGAAAGACCACCACCATAATGACTGCGCTTGGCATCGC
CCTCACGGTCGCCGTCCTGCTCGCCGTGCTCGCTCTTGTCGATGGCCTGCGCACTACCCTCGCCTCCTCCGGCGATCCAC
TGCAAATCATCGTCATGCGCAAAGGCTCCGAATCCGAAATCGTCAGCAACTTCACCCGCACCCAGTTCCAGGACCTCAAG
TTCAAGCCCGGCATCGTCCCCGGCAGCGACGGACAGCCCCTCGCCTCCCTCGAGGTCGTCTCCGTCATCAATCTCTCCAG
TTCGGAAACCGGCGAAGGCACCAACGTCACCGTCCGCGGGCTCCAACCCGCCGGCCTTGAAATGCGCCATGGAGTCAAGA
TCTCCAGCGGCCGCTGGTACCAGCAGGGACGCCGCGAGCTGGTGGTCGGCAAGAGCGTCGCCGACCGTTACCCCGAGGCC
CAAATCGGCCGCAAAATCAAATTCGGCCGGGGCGATTGGGATATCGTCGGTGTCATGGACGCCGGCCGCGGCGCCCAAGC
CAGCGAACTCTGGGGCGATCTCAACCAGGTCTCCGCCGACCTCCAGCGCGTCGAAGTCCTTTCCAGCGCCCTCGTGCGCG
CCACCGATGCTGTTACCGCCAAGGCCCTCGTCAACGACATTAATAATGATCAGCGCCTCAACATGAATGCGCTCTCCGAA
GCCGCCTACTATGAGGCCCAGACCGCTTCCGCCGCTCCTATTGAATACATCGGTATTTTTGTGGCGATTATCATGGCCGT
GGGCAGCGCGTTTGCCGCCATGAACACCATGTACGCCGCCGTCGCCCGCCGCTCCCGGGAAATCGGCACCCTTCGCGTTC
TCGGTTTCTCGAAGGGCAGCATCCTCGCCAGCTTCTTCTTCGAATCCGTGCTGCTTTCCGCTCTCGGCGGCGTTCTCGGC
TGCCTCCTCGTCCTGCCCCTCAACGGAATCACTACCGGCATCGGCAACGCCAACTTCTCCGAGACTGCCTTCAACTTTCA
TGTCTCGCCCCAAATCATGCTCAGCGGCATCGTCTTTGCCGTAATTCTAGGTGCGGCCGGCGGACTCTTCCCCGCCGGAA
ACGCCGCCCGCAAGGAAATTCTCACCGCCTTACGCGAAATCTAG

Upstream 100 bases:

>100_bases
GCATCTTGACGGCTGGCACCATCGGTTTGGTCAGCTCTCTCGTCCCGGCGCTTGGCGCCTCCCGTACCCCCATCGTCGAA
GCCCTGCGGAGTACCGACTA

Downstream 100 bases:

>100_bases
GCATCCAATCATTCCCTATGGACGAGGAACTCAAAAGTCTCCAGATCAATCGCTCCAAACGGCGTTCCACCGAGCCGTCC
CGCTGGGCCGCCCGCTGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MAIPVAYNLRNLVVRKTTTIMTALGIALTVAVLLAVLALVDGLRTTLASSGDPLQIIVMRKGSESEIVSNFTRTQFQDLK
FKPGIVPGSDGQPLASLEVVSVINLSSSETGEGTNVTVRGLQPAGLEMRHGVKISSGRWYQQGRRELVVGKSVADRYPEA
QIGRKIKFGRGDWDIVGVMDAGRGAQASELWGDLNQVSADLQRVEVLSSALVRATDAVTAKALVNDINNDQRLNMNALSE
AAYYEAQTASAAPIEYIGIFVAIIMAVGSAFAAMNTMYAAVARRSREIGTLRVLGFSKGSILASFFFESVLLSALGGVLG
CLLVLPLNGITTGIGNANFSETAFNFHVSPQIMLSGIVFAVILGAAGGLFPAGNAARKEILTALREI

Sequences:

>Translated_387_residues
MAIPVAYNLRNLVVRKTTTIMTALGIALTVAVLLAVLALVDGLRTTLASSGDPLQIIVMRKGSESEIVSNFTRTQFQDLK
FKPGIVPGSDGQPLASLEVVSVINLSSSETGEGTNVTVRGLQPAGLEMRHGVKISSGRWYQQGRRELVVGKSVADRYPEA
QIGRKIKFGRGDWDIVGVMDAGRGAQASELWGDLNQVSADLQRVEVLSSALVRATDAVTAKALVNDINNDQRLNMNALSE
AAYYEAQTASAAPIEYIGIFVAIIMAVGSAFAAMNTMYAAVARRSREIGTLRVLGFSKGSILASFFFESVLLSALGGVLG
CLLVLPLNGITTGIGNANFSETAFNFHVSPQIMLSGIVFAVILGAAGGLFPAGNAARKEILTALREI
>Mature_386_residues
AIPVAYNLRNLVVRKTTTIMTALGIALTVAVLLAVLALVDGLRTTLASSGDPLQIIVMRKGSESEIVSNFTRTQFQDLKF
KPGIVPGSDGQPLASLEVVSVINLSSSETGEGTNVTVRGLQPAGLEMRHGVKISSGRWYQQGRRELVVGKSVADRYPEAQ
IGRKIKFGRGDWDIVGVMDAGRGAQASELWGDLNQVSADLQRVEVLSSALVRATDAVTAKALVNDINNDQRLNMNALSEA
AYYEAQTASAAPIEYIGIFVAIIMAVGSAFAAMNTMYAAVARRSREIGTLRVLGFSKGSILASFFFESVLLSALGGVLGC
LLVLPLNGITTGIGNANFSETAFNFHVSPQIMLSGIVFAVILGAAGGLFPAGNAARKEILTALREI

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 40961; Mature: 40830

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPVAYNLRNLVVRKTTTIMTALGIALTVAVLLAVLALVDGLRTTLASSGDPLQIIVMR
CCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
KGSESEIVSNFTRTQFQDLKFKPGIVPGSDGQPLASLEVVSVINLSSSETGEGTNVTVRG
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCCCCCCEEEEEC
LQPAGLEMRHGVKISSGRWYQQGRRELVVGKSVADRYPEAQIGRKIKFGRGDWDIVGVMD
CCCCCCHHHCCEEECCCCHHHHCCCEEEECCHHHHHCCHHHHCCEEECCCCCEEEEEEEE
AGRGAQASELWGDLNQVSADLQRVEVLSSALVRATDAVTAKALVNDINNDQRLNMNALSE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHH
AAYYEAQTASAAPIEYIGIFVAIIMAVGSAFAAMNTMYAAVARRSREIGTLRVLGFSKGS
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCH
ILASFFFESVLLSALGGVLGCLLVLPLNGITTGIGNANFSETAFNFHVSPQIMLSGIVFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEECCHHHHHHHHHHH
VILGAAGGLFPAGNAARKEILTALREI
HHHHCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIPVAYNLRNLVVRKTTTIMTALGIALTVAVLLAVLALVDGLRTTLASSGDPLQIIVMR
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
KGSESEIVSNFTRTQFQDLKFKPGIVPGSDGQPLASLEVVSVINLSSSETGEGTNVTVRG
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCCCCCCEEEEEC
LQPAGLEMRHGVKISSGRWYQQGRRELVVGKSVADRYPEAQIGRKIKFGRGDWDIVGVMD
CCCCCCHHHCCEEECCCCHHHHCCCEEEECCHHHHHCCHHHHCCEEECCCCCEEEEEEEE
AGRGAQASELWGDLNQVSADLQRVEVLSSALVRATDAVTAKALVNDINNDQRLNMNALSE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHH
AAYYEAQTASAAPIEYIGIFVAIIMAVGSAFAAMNTMYAAVARRSREIGTLRVLGFSKGS
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCH
ILASFFFESVLLSALGGVLGCLLVLPLNGITTGIGNANFSETAFNFHVSPQIMLSGIVFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEECCHHHHHHHHHHH
VILGAAGGLFPAGNAARKEILTALREI
HHHHCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]