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The map label for this gene is ywlC [H]

Identifier: 116620704

GI number: 116620704

Start: 1944091

End: 1944957

Strand: Reverse

Name: ywlC [H]

Synonym: Acid_1584

Alternate gene names: 116620704

Gene position: 1944957-1944091 (Counterclockwise)

Preceding gene: 116620705

Following gene: 116620703

Centisome position: 19.52

GC content: 67.13

Gene sequence:

>867_bases
ATGGCGTATGCCGCCGAGCTGATCCGCGGCGGCAAACTCGTTGCCTTCCCCACCGAGACCGTCTACGGACTCGGCGCCAA
CGCGCTCGACGCCGATGCGGTAGCCCGCATCTTCGAGGCGAAAGGCCGGCCGCGCACCAGTCCCTTGATCGTCCATGTGG
ACTCGGTGGAAATGGCCCAGACGCTCTCCGACGACTGGCCCGACACCGCCGAGCTCCTGGCCCGCATCTATTGGCCGGGA
CCGCTCACGCTTGTCGTCGCCAAGCATCCCGGCATTCCGGATATCGTGACCGCCGGGCTGCCGACGGTGGGCCTGCGCAT
GCCCGCGCATCCCATGGCCCTCGAGTTGATTCGTGAAGCCGGCGTCCCCATCGCGGCGCCGAGCGCGAATCGATTTACCG
AGCTCTCCCCCACCTCCGCGGCCCACATTCCCGAATCGCTGGCAGACTTCACTTTAGATGGCGGGCCATCGCAGGTGGGA
ATCGAATCCACCGTGCTCTCGCTCGTCGCCGGGCCCACGCTCCTGCGGCCGGGGGTCATCCCCGTGGACGAATTGGAATC
GCTGATCGGGCCCATCGCGCGGGGAGTCGCGCATGTGCAGGATGCGCATCCCGCACCGGGTATGCACACGCGCCACTATC
GCCCCAGCACCCCACTCTATCTGGGCGAGTTCCCCGCCGAAGGCAAGGGTGTCTTCCTGCGCATCGGCTACGAAATGCCG
GAAGATCCGCGCGCCTACGCGGCGGCGCTCTACGAAACACTCCACCATCTCGATACCGAGGGCCTGGACTGGATCGCAGT
CGAAGTTCCGCCCGACACACCGGAATGGGCCGGTGTGCTGGACCGCTTGCGCCGCGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
GACTCGACCCGCTGATTCACTCCTACCTGGTGTGGCGCAAAACCGGCAAGATCGCGGGCGATGATAAAGACGAGTCGCCA
GAGTGACACCCGAAGCCAAC

Downstream 100 bases:

>100_bases
AATCTCGATATGAGGCTGCTGCTGTTGCTGGCTTTGTTGGCCGCACCCGCGAATGCGAAGAAGGAATTGAAGTGGGTGCC
CGCGCTGGTCGAATCGAGTT

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MAYAAELIRGGKLVAFPTETVYGLGANALDADAVARIFEAKGRPRTSPLIVHVDSVEMAQTLSDDWPDTAELLARIYWPG
PLTLVVAKHPGIPDIVTAGLPTVGLRMPAHPMALELIREAGVPIAAPSANRFTELSPTSAAHIPESLADFTLDGGPSQVG
IESTVLSLVAGPTLLRPGVIPVDELESLIGPIARGVAHVQDAHPAPGMHTRHYRPSTPLYLGEFPAEGKGVFLRIGYEMP
EDPRAYAAALYETLHHLDTEGLDWIAVEVPPDTPEWAGVLDRLRRAAE

Sequences:

>Translated_288_residues
MAYAAELIRGGKLVAFPTETVYGLGANALDADAVARIFEAKGRPRTSPLIVHVDSVEMAQTLSDDWPDTAELLARIYWPG
PLTLVVAKHPGIPDIVTAGLPTVGLRMPAHPMALELIREAGVPIAAPSANRFTELSPTSAAHIPESLADFTLDGGPSQVG
IESTVLSLVAGPTLLRPGVIPVDELESLIGPIARGVAHVQDAHPAPGMHTRHYRPSTPLYLGEFPAEGKGVFLRIGYEMP
EDPRAYAAALYETLHHLDTEGLDWIAVEVPPDTPEWAGVLDRLRRAAE
>Mature_287_residues
AYAAELIRGGKLVAFPTETVYGLGANALDADAVARIFEAKGRPRTSPLIVHVDSVEMAQTLSDDWPDTAELLARIYWPGP
LTLVVAKHPGIPDIVTAGLPTVGLRMPAHPMALELIREAGVPIAAPSANRFTELSPTSAAHIPESLADFTLDGGPSQVGI
ESTVLSLVAGPTLLRPGVIPVDELESLIGPIARGVAHVQDAHPAPGMHTRHYRPSTPLYLGEFPAEGKGVFLRIGYEMPE
DPRAYAAALYETLHHLDTEGLDWIAVEVPPDTPEWAGVLDRLRRAAE

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=132, Percent_Identity=30.3030303030303, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17537239, Length=198, Percent_Identity=30.3030303030303, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=327, Percent_Identity=35.474006116208, Blast_Score=156, Evalue=4e-39,
Organism=Drosophila melanogaster, GI78707274, Length=135, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 30792; Mature: 30660

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYAAELIRGGKLVAFPTETVYGLGANALDADAVARIFEAKGRPRTSPLIVHVDSVEMAQ
CCCHHHHHCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCHHHHH
TLSDDWPDTAELLARIYWPGPLTLVVAKHPGIPDIVTAGLPTVGLRMPAHPMALELIREA
HHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHC
GVPIAAPSANRFTELSPTSAAHIPESLADFTLDGGPSQVGIESTVLSLVAGPTLLRPGVI
CCCEECCCCCCCCCCCCCCHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCC
PVDELESLIGPIARGVAHVQDAHPAPGMHTRHYRPSTPLYLGEFPAEGKGVFLRIGYEMP
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCC
EDPRAYAAALYETLHHLDTEGLDWIAVEVPPDTPEWAGVLDRLRRAAE
CCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYAAELIRGGKLVAFPTETVYGLGANALDADAVARIFEAKGRPRTSPLIVHVDSVEMAQ
CCHHHHHCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCHHHHH
TLSDDWPDTAELLARIYWPGPLTLVVAKHPGIPDIVTAGLPTVGLRMPAHPMALELIREA
HHCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHC
GVPIAAPSANRFTELSPTSAAHIPESLADFTLDGGPSQVGIESTVLSLVAGPTLLRPGVI
CCCEECCCCCCCCCCCCCCHHHCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCC
PVDELESLIGPIARGVAHVQDAHPAPGMHTRHYRPSTPLYLGEFPAEGKGVFLRIGYEMP
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCC
EDPRAYAAALYETLHHLDTEGLDWIAVEVPPDTPEWAGVLDRLRRAAE
CCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]