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The map label for this gene is mdtA [H]

Identifier: 116620701

GI number: 116620701

Start: 1939641

End: 1940891

Strand: Reverse

Name: mdtA [H]

Synonym: Acid_1581

Alternate gene names: 116620701

Gene position: 1940891-1939641 (Counterclockwise)

Preceding gene: 116620703

Following gene: 116620700

Centisome position: 19.48

GC content: 59.79

Gene sequence:

>1251_bases
ATGGATGAACCCACCACGCAGCCTTCTCCCCCTTCGAAGCGCTCTTCCCGGTCGCGATGGCTGTGGCTTCTGTTGGTGGC
GGTGATCGCAGTCGCCGTTTACTACTACCGCTCCTCCGAAGCCAAGGGCGCCGGTGCCGGAAATCCTTCCGTCGCTTCGA
AAAAGAAGGGTGGCAAGGGCGGCGGTGAAGGGGCTGTTCCGGTGGTGGGCACACGCGCCCGCAGAGGCAACATCGGCGTC
TACATCAATGGCTTGGGCTCGGTTACGCCGATTTATACCGTCACGTTAAAGAGCCGCGTGGATGGCGAACTGATGTCGGT
TCACTTTCGCGAAGGTGACACGGTTCACAAAGGCGATCTCCTGATGGAGATCGATCCGCGCCCCTATCAGGTGCAGCTGA
CGCAAGCCGAAGGTCAACTTGCCAGAGACCAGGCGACTCTGGAAAATGCGCGCACCGACCTCACTCGCTACGAGGGATTG
TTGAAGCTCAATGCAATTCCTGAGCAGCAGGTGGCAACTCAAAGGTCCACCGTCAAGCAATCCGAAGCCACCGTCAAATC
CGACGAGGGACAGGTGGCGAGCGCCAACCTGAACCTGACCTATAGCCACATCATTTCGCCGATCACCGGACGCCTCGGCT
TGCGCCTGGTGGACCCCGGAAACATCGTGCATGCGAGCGATCCCAACGGTTTGGTCGTGATCACCCAAATGGACCCGATC
AGCGTGCTATTCACGATTTCCGAGGACCAGCTCCCTACCGTGCTGCAAAAAATGCGCGCCGGGCAAACCTTGACCGTGGA
TGCGTTCGACCGCGAGATGAAACACAAGATCGCCAGTGGCACCCTGACCACGGTGGATAACGAGATCGACCCCACCACCG
GAACCGTTCGCTTGCGCGCAACCTTCGCCAACAGCAACGGCGCGCTGTTTCCCAGCCAGTTTGTGAACGCGCGACTGCTG
GTGCAGCAGAAGCACGGCGTTGTACTGCTTGCCAACGCCGCAATTCAACGAACATCCAACACAATCTTCGTCTATCTGGT
GAAACCGGATTCCACCGTAACCGTTCGGAACGTCACCACCGGCACCACCGAGGGAGAGGACGTGGAGGTCGCTTCCGGGC
TTAACCCCGGAGACGTGGTGGTCATGACCGGCGCCGACAAGTTACAGGAGGGGAGCAAGGTTCGAGTGGAAATCCCTGGC
GATAACGAGAAGCAGGCCGGCGGCCGCGCGGCAAAGGGCGGACACAGGTGA

Upstream 100 bases:

>100_bases
GGGTGGCGGATTAGTCAAATGGAGCTAATCGGTAACCCGGCTGGTGTCGCGCCGCGCCTTGTCGAATAGAGCCTCTCGTT
GAGCGGAAACTCACATCACT

Downstream 100 bases:

>100_bases
GCCCTTCCCGTACTTTCATTCTTCGTCCCGTGGCGACTTCCCTCCTGATGGTGGGCATTCTGCTGGCAGGAATCGTCGCC
TATCAACAGCTTCCGGTGTC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDEPTTQPSPPSKRSSRSRWLWLLLVAVIAVAVYYYRSSEAKGAGAGNPSVASKKKGGKGGGEGAVPVVGTRARRGNIGV
YINGLGSVTPIYTVTLKSRVDGELMSVHFREGDTVHKGDLLMEIDPRPYQVQLTQAEGQLARDQATLENARTDLTRYEGL
LKLNAIPEQQVATQRSTVKQSEATVKSDEGQVASANLNLTYSHIISPITGRLGLRLVDPGNIVHASDPNGLVVITQMDPI
SVLFTISEDQLPTVLQKMRAGQTLTVDAFDREMKHKIASGTLTTVDNEIDPTTGTVRLRATFANSNGALFPSQFVNARLL
VQQKHGVVLLANAAIQRTSNTIFVYLVKPDSTVTVRNVTTGTTEGEDVEVASGLNPGDVVVMTGADKLQEGSKVRVEIPG
DNEKQAGGRAAKGGHR

Sequences:

>Translated_416_residues
MDEPTTQPSPPSKRSSRSRWLWLLLVAVIAVAVYYYRSSEAKGAGAGNPSVASKKKGGKGGGEGAVPVVGTRARRGNIGV
YINGLGSVTPIYTVTLKSRVDGELMSVHFREGDTVHKGDLLMEIDPRPYQVQLTQAEGQLARDQATLENARTDLTRYEGL
LKLNAIPEQQVATQRSTVKQSEATVKSDEGQVASANLNLTYSHIISPITGRLGLRLVDPGNIVHASDPNGLVVITQMDPI
SVLFTISEDQLPTVLQKMRAGQTLTVDAFDREMKHKIASGTLTTVDNEIDPTTGTVRLRATFANSNGALFPSQFVNARLL
VQQKHGVVLLANAAIQRTSNTIFVYLVKPDSTVTVRNVTTGTTEGEDVEVASGLNPGDVVVMTGADKLQEGSKVRVEIPG
DNEKQAGGRAAKGGHR
>Mature_416_residues
MDEPTTQPSPPSKRSSRSRWLWLLLVAVIAVAVYYYRSSEAKGAGAGNPSVASKKKGGKGGGEGAVPVVGTRARRGNIGV
YINGLGSVTPIYTVTLKSRVDGELMSVHFREGDTVHKGDLLMEIDPRPYQVQLTQAEGQLARDQATLENARTDLTRYEGL
LKLNAIPEQQVATQRSTVKQSEATVKSDEGQVASANLNLTYSHIISPITGRLGLRLVDPGNIVHASDPNGLVVITQMDPI
SVLFTISEDQLPTVLQKMRAGQTLTVDAFDREMKHKIASGTLTTVDNEIDPTTGTVRLRATFANSNGALFPSQFVNARLL
VQQKHGVVLLANAAIQRTSNTIFVYLVKPDSTVTVRNVTTGTTEGEDVEVASGLNPGDVVVMTGADKLQEGSKVRVEIPG
DNEKQAGGRAAKGGHR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=389, Percent_Identity=42.4164524421594, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI1789929, Length=327, Percent_Identity=32.1100917431193, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786668, Length=329, Percent_Identity=31.0030395136778, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789665, Length=315, Percent_Identity=29.2063492063492, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44558; Mature: 44558

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEPTTQPSPPSKRSSRSRWLWLLLVAVIAVAVYYYRSSEAKGAGAGNPSVASKKKGGKG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCC
GGEGAVPVVGTRARRGNIGVYINGLGSVTPIYTVTLKSRVDGELMSVHFREGDTVHKGDL
CCCCCCEEEECCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEEEEEECCCCEEECCCE
LMEIDPRPYQVQLTQAEGQLARDQATLENARTDLTRYEGLLKLNAIPEQQVATQRSTVKQ
EEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHH
SEATVKSDEGQVASANLNLTYSHIISPITGRLGLRLVDPGNIVHASDPNGLVVITQMDPI
HHCEEECCCCCEEEEEEEEEHHHHHCCCCCCCCEEEECCCCEEEECCCCCEEEEEECCCE
SVLFTISEDQLPTVLQKMRAGQTLTVDAFDREMKHKIASGTLTTVDNEIDPTTGTVRLRA
EEEEEECCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEE
TFANSNGALFPSQFVNARLLVQQKHGVVLLANAAIQRTSNTIFVYLVKPDSTVTVRNVTT
EEECCCCCCCHHHHCCEEEEEEECCCEEEEEECEEECCCCEEEEEEECCCCEEEEEEEEC
GTTEGEDVEVASGLNPGDVVVMTGADKLQEGSKVRVEIPGDNEKQAGGRAAKGGHR
CCCCCCCEEEECCCCCCCEEEEECCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDEPTTQPSPPSKRSSRSRWLWLLLVAVIAVAVYYYRSSEAKGAGAGNPSVASKKKGGKG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCC
GGEGAVPVVGTRARRGNIGVYINGLGSVTPIYTVTLKSRVDGELMSVHFREGDTVHKGDL
CCCCCCEEEECCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEEEEEECCCCEEECCCE
LMEIDPRPYQVQLTQAEGQLARDQATLENARTDLTRYEGLLKLNAIPEQQVATQRSTVKQ
EEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHH
SEATVKSDEGQVASANLNLTYSHIISPITGRLGLRLVDPGNIVHASDPNGLVVITQMDPI
HHCEEECCCCCEEEEEEEEEHHHHHCCCCCCCCEEEECCCCEEEECCCCCEEEEEECCCE
SVLFTISEDQLPTVLQKMRAGQTLTVDAFDREMKHKIASGTLTTVDNEIDPTTGTVRLRA
EEEEEECCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEE
TFANSNGALFPSQFVNARLLVQQKHGVVLLANAAIQRTSNTIFVYLVKPDSTVTVRNVTT
EEECCCCCCCHHHHCCEEEEEEECCCEEEEEECEEECCCCEEEEEEECCCCEEEEEEEEC
GTTEGEDVEVASGLNPGDVVVMTGADKLQEGSKVRVEIPGDNEKQAGGRAAKGGHR
CCCCCCCEEEECCCCCCCEEEEECCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA