Click here to switch to the map view.

The map label for this gene is cirA [H]

Identifier: 116620664

GI number: 116620664

Start: 1895908

End: 1897968

Strand: Direct

Name: cirA [H]

Synonym: Acid_1544

Alternate gene names: 116620664

Gene position: 1895908-1897968 (Clockwise)

Preceding gene: 116620663

Following gene: 116620665

Centisome position: 19.02

GC content: 60.89

Gene sequence:

>2061_bases
GTGATAACTTGGTGTGATACACACCAGAGGAGGAGGGCTTTTCTGAACGGCGTCGTCCCATCGGTCTTGATCCCTTTGTT
TTTGGTGGCTCAGACCGCAGTTGCATCTCCCCAACAACCTCCCGCCGCGCCGGCCCCCCCTTTGGAACTCAAGCGACTGA
GCCTGGAAGAGCTTTCCCGGATTGAAGTTGTCTCACCCTCCAAAGAGCCCGAGAAGGCGATGCGCGTTCCGATGGCGATC
TACGTGATCACCGGCGATGAGATTCGGCGCTCCGGAGCCACCAGCATCCCGGAAGCGCTGCGCCTGGCCCCAGGTGTTGA
TGTTGCCCGGATCGACGGGAACAAGTGGTCGATCGGGGTTCGAGGCTTCGGCAGTCGCCTATCCCGCTCGGTCCTTGTCC
TCATCGACGGCCGTACCGTGTACACTACGTTCTTCGCGGGCACTTACTGGGAAGTGCAGGACACGGTAATGGATGATATC
GACCGCATCGAAGTCATCCGCGGACCCGGCGGTACCATCTGGGGGCCGAACGCGGTAAACGGCGTCATCAACATCATCAC
CAAACACACCCGGGATACCCACGGCACACTGGCCTCCGTAAGCAGCGGCAGCGAGGAGCAGGGCGCCTTCAAGGTCCGCT
ACGGCGGAGGGAACGGAGCCACGCTTGACTATCGGATCTACGGCAAGGGCTTTACACGCGGACCCGAGTATCATCCGGAT
GCCCGGAACTTCGACGATTGGCGCGCGGCCCAAACCGGGTTCCGCGTGGATTGGTCAAACCGGCCGCGCGAGACCATCAC
AGTGCAGGGCGATCTCTATCGCGAAGAGGCGGGCGAACGCGTTACCGCCACGAGCTACACCCCTCCCTACACCCGCGACA
TTGACGGCAACGCGCACCTTTCGGGCGGCAATATTCTCGCTCGCTGGAAGAAGGACCTGGATAGTGGTGATCTTCAGGTG
CAGGCCTACTACGATCGCACCAATCGCTTCGAGCCGAATTTCGATGAGAGCCGCGATACCTTCGACATTGACTTTCTGCA
TCACATGCGGCTGCCGAAGGACCAGCAATTGCTGTGGGGCCTCGGCGCCCGCGTCAGCGTGGGCAAGGCCCCGCCGGTTG
TCTCGGGACTTACCTTCGATCCGCAGAATCGTACCGACCAGCTCTACACCGCGTTCCTGCAGGACGAGATCGGGCTTGTC
GATCGACGCCTCTCGCTCACGTTGGGAACCAAGCTGCTCCGTACCAACTTCACCAGCATTGATTTTGAACCTAGTGCCCG
CCTGGCCTGGACTCCGACCGACAACCAGACGGTCTGGGCGGCCTTCACCCACTCCCTGCGTACGCCGTCGCGCGCGGAGG
AGGACTTCAATCTCTCCGGCTACATCACCACGGCGGCCGGCGTGCCTTACTTTGCCCGCTTCAACGCCAACCGGAACTTT
GCACCCGAACAGCTCAACGGTTACGAGCTTGGCTATCGCCGGCTGATGCGCCATAACGTCTTCATCGATGTCGCGACGTT
CTATAACCACTATCACGATCTTTTCAGCGAAGATATCACCGGCCCCACGTTCTTCGAGAGCACTCCCGCTCCGCCGCACC
TGCTGCTGCCGGCGCAGTTCCGCAACGATCTGTTGGGCGTCACCACGGGAGTGGAGGTTGCCCCGGAATGGCGGCCCACT
TCCTTTTGGCGATTGCGTGGTTCATATTCGTTCTTACATATCGATCTCAAGAAAGCGCCGGGCACCGCGGAAATCGGGAC
CGCGCCGCAGATCGAAGGCGCCAGTCCTCAGCATCAGGGCCTCTTTGAATCCTCGTGGGAGCTTACCAGGAAGCTCGAAC
TCGACCTCACCTACCGCTATGTCGGCGCGCTTCCCAGCCAGGCTGTGCCGTCATACTCAACCGGGGATGCGCGGTTTGCC
TGGCGCGTCTCGCGTCAGTTGGAGGTCTCGGCGGTGGGCAGAAATCTGCTCCAGCCGTGGCACTTCGAGTATCTTGGCGA
TCCGGGCTCGCTGGTCGGTATCAAGAGAAGTGGTTACCTCAGCCTGACGTGGACCAGGTAA

Upstream 100 bases:

>100_bases
GCCGCGAGAGCATTATTCAGGCCCTCTCCACGGCCGATGGTCCCATAGCCTCCGATTAGTTAGTTAGCGAACACAGGCGG
GCGCGTCTGCCATTCCCTCG

Downstream 100 bases:

>100_bases
ACCCATGCGAACCTCCGCATTGCTGGTGATGTTCCTGCTGGCCCGTTCCATGCTGCCTCAGATGCGGGCTCCGGCCTCCG
AGTATCAGGTGAAGGCTGCA

Product: TonB-dependent receptor, plug

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MITWCDTHQRRRAFLNGVVPSVLIPLFLVAQTAVASPQQPPAAPAPPLELKRLSLEELSRIEVVSPSKEPEKAMRVPMAI
YVITGDEIRRSGATSIPEALRLAPGVDVARIDGNKWSIGVRGFGSRLSRSVLVLIDGRTVYTTFFAGTYWEVQDTVMDDI
DRIEVIRGPGGTIWGPNAVNGVINIITKHTRDTHGTLASVSSGSEEQGAFKVRYGGGNGATLDYRIYGKGFTRGPEYHPD
ARNFDDWRAAQTGFRVDWSNRPRETITVQGDLYREEAGERVTATSYTPPYTRDIDGNAHLSGGNILARWKKDLDSGDLQV
QAYYDRTNRFEPNFDESRDTFDIDFLHHMRLPKDQQLLWGLGARVSVGKAPPVVSGLTFDPQNRTDQLYTAFLQDEIGLV
DRRLSLTLGTKLLRTNFTSIDFEPSARLAWTPTDNQTVWAAFTHSLRTPSRAEEDFNLSGYITTAAGVPYFARFNANRNF
APEQLNGYELGYRRLMRHNVFIDVATFYNHYHDLFSEDITGPTFFESTPAPPHLLLPAQFRNDLLGVTTGVEVAPEWRPT
SFWRLRGSYSFLHIDLKKAPGTAEIGTAPQIEGASPQHQGLFESSWELTRKLELDLTYRYVGALPSQAVPSYSTGDARFA
WRVSRQLEVSAVGRNLLQPWHFEYLGDPGSLVGIKRSGYLSLTWTR

Sequences:

>Translated_686_residues
MITWCDTHQRRRAFLNGVVPSVLIPLFLVAQTAVASPQQPPAAPAPPLELKRLSLEELSRIEVVSPSKEPEKAMRVPMAI
YVITGDEIRRSGATSIPEALRLAPGVDVARIDGNKWSIGVRGFGSRLSRSVLVLIDGRTVYTTFFAGTYWEVQDTVMDDI
DRIEVIRGPGGTIWGPNAVNGVINIITKHTRDTHGTLASVSSGSEEQGAFKVRYGGGNGATLDYRIYGKGFTRGPEYHPD
ARNFDDWRAAQTGFRVDWSNRPRETITVQGDLYREEAGERVTATSYTPPYTRDIDGNAHLSGGNILARWKKDLDSGDLQV
QAYYDRTNRFEPNFDESRDTFDIDFLHHMRLPKDQQLLWGLGARVSVGKAPPVVSGLTFDPQNRTDQLYTAFLQDEIGLV
DRRLSLTLGTKLLRTNFTSIDFEPSARLAWTPTDNQTVWAAFTHSLRTPSRAEEDFNLSGYITTAAGVPYFARFNANRNF
APEQLNGYELGYRRLMRHNVFIDVATFYNHYHDLFSEDITGPTFFESTPAPPHLLLPAQFRNDLLGVTTGVEVAPEWRPT
SFWRLRGSYSFLHIDLKKAPGTAEIGTAPQIEGASPQHQGLFESSWELTRKLELDLTYRYVGALPSQAVPSYSTGDARFA
WRVSRQLEVSAVGRNLLQPWHFEYLGDPGSLVGIKRSGYLSLTWTR
>Mature_686_residues
MITWCDTHQRRRAFLNGVVPSVLIPLFLVAQTAVASPQQPPAAPAPPLELKRLSLEELSRIEVVSPSKEPEKAMRVPMAI
YVITGDEIRRSGATSIPEALRLAPGVDVARIDGNKWSIGVRGFGSRLSRSVLVLIDGRTVYTTFFAGTYWEVQDTVMDDI
DRIEVIRGPGGTIWGPNAVNGVINIITKHTRDTHGTLASVSSGSEEQGAFKVRYGGGNGATLDYRIYGKGFTRGPEYHPD
ARNFDDWRAAQTGFRVDWSNRPRETITVQGDLYREEAGERVTATSYTPPYTRDIDGNAHLSGGNILARWKKDLDSGDLQV
QAYYDRTNRFEPNFDESRDTFDIDFLHHMRLPKDQQLLWGLGARVSVGKAPPVVSGLTFDPQNRTDQLYTAFLQDEIGLV
DRRLSLTLGTKLLRTNFTSIDFEPSARLAWTPTDNQTVWAAFTHSLRTPSRAEEDFNLSGYITTAAGVPYFARFNANRNF
APEQLNGYELGYRRLMRHNVFIDVATFYNHYHDLFSEDITGPTFFESTPAPPHLLLPAQFRNDLLGVTTGVEVAPEWRPT
SFWRLRGSYSFLHIDLKKAPGTAEIGTAPQIEGASPQHQGLFESSWELTRKLELDLTYRYVGALPSQAVPSYSTGDARFA
WRVSRQLEVSAVGRNLLQPWHFEYLGDPGSLVGIKRSGYLSLTWTR

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=138, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790405, Length=147, Percent_Identity=34.0136054421769, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76885; Mature: 76885

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITWCDTHQRRRAFLNGVVPSVLIPLFLVAQTAVASPQQPPAAPAPPLELKRLSLEELSR
CCEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHCE
IEVVSPSKEPEKAMRVPMAIYVITGDEIRRSGATSIPEALRLAPGVDVARIDGNKWSIGV
EEEECCCCCHHHHHCCCEEEEEEECHHHHHCCCCCCHHHHHHCCCCEEEEECCCEEEEEE
RGFGSRLSRSVLVLIDGRTVYTTFFAGTYWEVQDTVMDDIDRIEVIRGPGGTIWGPNAVN
CCCCHHCCCEEEEEECCCEEEEEEECCEEEEEHHHHHCCCCEEEEEECCCCCCCCCHHHH
GVINIITKHTRDTHGTLASVSSGSEEQGAFKVRYGGGNGATLDYRIYGKGFTRGPEYHPD
HHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCC
ARNFDDWRAAQTGFRVDWSNRPRETITVQGDLYREEAGERVTATSYTPPYTRDIDGNAHL
CCCCCHHHHHCCCCEEECCCCCCEEEEEECCEEHHHCCCEEEEECCCCCCCCCCCCCEEE
SGGNILARWKKDLDSGDLQVQAYYDRTNRFEPNFDESRDTFDIDFLHHMRLPKDQQLLWG
CCCCEEEEEHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEHHHHCCCCCCHHHHHC
LGARVSVGKAPPVVSGLTFDPQNRTDQLYTAFLQDEIGLVDRRLSLTLGTKLLRTNFTSI
CCCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCCCEE
DFEPSARLAWTPTDNQTVWAAFTHSLRTPSRAEEDFNLSGYITTAAGVPYFARFNANRNF
ECCCCCCEEECCCCCCEEEEEEHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCC
APEQLNGYELGYRRLMRHNVFIDVATFYNHYHDLFSEDITGPTFFESTPAPPHLLLPAQF
CCHHCCCHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEECHHH
RNDLLGVTTGVEVAPEWRPTSFWRLRGSYSFLHIDLKKAPGTAEIGTAPQIEGASPQHQG
CCCEEEEECCCEECCCCCCCCEEEEECCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
LFESSWELTRKLELDLTYRYVGALPSQAVPSYSTGDARFAWRVSRQLEVSAVGRNLLQPW
CCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCEEEHHHHHHHHCCCC
HFEYLGDPGSLVGIKRSGYLSLTWTR
CCEEECCCCCEEEEECCCEEEEEEEC
>Mature Secondary Structure
MITWCDTHQRRRAFLNGVVPSVLIPLFLVAQTAVASPQQPPAAPAPPLELKRLSLEELSR
CCEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHCE
IEVVSPSKEPEKAMRVPMAIYVITGDEIRRSGATSIPEALRLAPGVDVARIDGNKWSIGV
EEEECCCCCHHHHHCCCEEEEEEECHHHHHCCCCCCHHHHHHCCCCEEEEECCCEEEEEE
RGFGSRLSRSVLVLIDGRTVYTTFFAGTYWEVQDTVMDDIDRIEVIRGPGGTIWGPNAVN
CCCCHHCCCEEEEEECCCEEEEEEECCEEEEEHHHHHCCCCEEEEEECCCCCCCCCHHHH
GVINIITKHTRDTHGTLASVSSGSEEQGAFKVRYGGGNGATLDYRIYGKGFTRGPEYHPD
HHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCC
ARNFDDWRAAQTGFRVDWSNRPRETITVQGDLYREEAGERVTATSYTPPYTRDIDGNAHL
CCCCCHHHHHCCCCEEECCCCCCEEEEEECCEEHHHCCCEEEEECCCCCCCCCCCCCEEE
SGGNILARWKKDLDSGDLQVQAYYDRTNRFEPNFDESRDTFDIDFLHHMRLPKDQQLLWG
CCCCEEEEEHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEHHHHCCCCCCHHHHHC
LGARVSVGKAPPVVSGLTFDPQNRTDQLYTAFLQDEIGLVDRRLSLTLGTKLLRTNFTSI
CCCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCCCEE
DFEPSARLAWTPTDNQTVWAAFTHSLRTPSRAEEDFNLSGYITTAAGVPYFARFNANRNF
ECCCCCCEEECCCCCCEEEEEEHHHCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCC
APEQLNGYELGYRRLMRHNVFIDVATFYNHYHDLFSEDITGPTFFESTPAPPHLLLPAQF
CCHHCCCHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEECHHH
RNDLLGVTTGVEVAPEWRPTSFWRLRGSYSFLHIDLKKAPGTAEIGTAPQIEGASPQHQG
CCCEEEEECCCEECCCCCCCCEEEEECCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
LFESSWELTRKLELDLTYRYVGALPSQAVPSYSTGDARFAWRVSRQLEVSAVGRNLLQPW
CCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCEEEHHHHHHHHCCCC
HFEYLGDPGSLVGIKRSGYLSLTWTR
CCEEECCCCCEEEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]