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The map label for this gene is insF1 [C]

Identifier: 116620625

GI number: 116620625

Start: 1841868

End: 1843139

Strand: Direct

Name: insF1 [C]

Synonym: Acid_1504

Alternate gene names: 116620625

Gene position: 1841868-1843139 (Clockwise)

Preceding gene: 116620624

Following gene: 116620630

Centisome position: 18.48

GC content: 59.36

Gene sequence:

>1272_bases
ATGACGCAAGAGCAAGGCAAGTTAAGCATCCAACGGATGTGCCAACTCGTCGGCGTCAGCCGGGCCGGATATTACCGGCA
CTGGGAGGTCGTAGCTCCGGACGAAGCGGAAATGGCGGCCAGGGATGCCATCCAGAAGGTGGTGCTCGCGCACCATCGAC
GGTACGGCTACCGGCGCGTCACCGCGCAACTGCATCGACAGGGAAACATCATCAATCACAAGCGGGTGCTGCGCATTATG
GGTGAGGACAACCTGCTGGCGATCCGCTACCGCAAGTACATTATGACCACCGATTCGCGGCACGACTACCCGGTCTACGT
GAATCTGGCTGCGCGCATGACATTGACCGGCATCAACCAGCTGTGGATCGCCGACATCACCTACATCCGGCTGCGCAGGG
AGTTTGTCTATCTGGCGATCGTGCTCGACCGATTCTCACGTAAGGCAATCGGTTGGTCGCTGGATCGGGCGCTGGCTGCC
CGAATCGCGGTGGCGGCCTTGGAGCAGGCCGTGGAGAGACGGCAGCCGCCGCCGGGCGTGGTGGTGCACAACGATCAGGG
TATCCAGTTTGTCTGCCACGAATTTCAAGAGGTGGTGAAAGCTCACGGGATGGTGCCCAGCCTGAGCCGCCCGGCGAATC
CGTACGACAATGCCGCCTGTGAAAGTTTCATGAAGACGCTGAAGCAGGAGGAAATCTACTGCCACCGGTACCAGGATTTC
GATGAACTTTCCGCCCATGTGGAAGAGTTCATCGAAACCTACTACAACCGGCAACGGCTGCACTCGGCACTGGGCTATCG
GACGCCGGAAGAATTTGAGCGGGATGGCATCTCAGCCCCGAATTCCGGCACCCACAATGCGGGCGACCATGCTGGTGTTT
ACTCCGAAGGAAGAAGAGGGTTCCGGCGGGCCAGATTCCATCTCTCCGCGATGACTCAGGCAAAGAAATGGCACGAAAGG
CAAAGTTCGCCCGCTACCGGGAACATCTCCGCACGACCGGGCCGGTCAGCCCTGGGGGGTCTTCCATCGTCAAGGAGAAT
GGCGACGATCCCTTATCTGTGCCACTTCAATGAATCAATACTGGGGCCCCAGTATGCGTTTTCGAGGCATCGCGGAATCT
ATCGGTCCGATGTGGTCCAAACTACAACCAATCCTGGGACAGGGGCTGACCTCCTCCCGTCGCTCAGCCCCCGGTCCCAG
GCAAAAGAACGCGTCGGGAGGACCACGCTCTTCTCATCGTCCGCGATGAGTTCCGATCCGGCTATTCCTTGA

Upstream 100 bases:

>100_bases
ATAAAGTCCTGGAGATCGAGCTTTTTCAACATGCCTTGCTCAAATTAAAGGAGGCACGGCCACAGCCTGGCGCCTCAGCG
TCTACGAAGTCATCCGTTCG

Downstream 100 bases:

>100_bases
TCGGGTTGCTCGCCAGCAGAGCCCGTCTCCGCTTCACCGGACACCAGCGATCATAAAACCTGGACGGAAAAGCGAAAACA
GAATATCATCGAACGGTAAC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRIM
GEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQLWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAA
RIAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDF
DELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAGDHAGVYSEGRRGFRRARFHLSAMTQAKKWHER
QSSPATGNISARPGRSALGGLPSSRRMATIPYLCHFNESILGPQYAFSRHRGIYRSDVVQTTTNPGTGADLLPSLSPRSQ
AKERVGRTTLFSSSAMSSDPAIP

Sequences:

>Translated_423_residues
MTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRIM
GEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQLWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAA
RIAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDF
DELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAGDHAGVYSEGRRGFRRARFHLSAMTQAKKWHER
QSSPATGNISARPGRSALGGLPSSRRMATIPYLCHFNESILGPQYAFSRHRGIYRSDVVQTTTNPGTGADLLPSLSPRSQ
AKERVGRTTLFSSSAMSSDPAIP
>Mature_422_residues
TQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRIMG
EDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQLWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAAR
IAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDFD
ELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAGDHAGVYSEGRRGFRRARFHLSAMTQAKKWHERQ
SSPATGNISARPGRSALGGLPSSRRMATIPYLCHFNESILGPQYAFSRHRGIYRSDVVQTTTNPGTGADLLPSLSPRSQA
KERVGRTTLFSSSAMSSDPAIP

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=237, Percent_Identity=28.6919831223629, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1788405, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787263, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786753, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786570, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786490, Length=283, Percent_Identity=34.982332155477, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1789981, Length=258, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790724, Length=231, Percent_Identity=29.8701298701299, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789424, Length=231, Percent_Identity=29.8701298701299, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789224, Length=231, Percent_Identity=29.8701298701299, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788305, Length=231, Percent_Identity=29.8701298701299, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787669, Length=231, Percent_Identity=29.8701298701299, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786558, Length=231, Percent_Identity=29.8701298701299, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 48070; Mature: 47939

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRV
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHH
TAQLHRQGNIINHKRVLRIMGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQ
HHHHHHCCCCCCHHHHHHEECCCCEEEEEEEEHEEECCCCCCCCEEEEEEHHEEHHCCCH
LWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDF
EEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
DELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAGDHAGVYSEGRRG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
FRRARFHLSAMTQAKKWHERQSSPATGNISARPGRSALGGLPSSRRMATIPYLCHFNESI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCEEECCHHEECCCCC
LGPQYAFSRHRGIYRSDVVQTTTNPGTGADLLPSLSPRSQAKERVGRTTLFSSSAMSSDP
CCCHHHHHHHCCCHHHHCEEECCCCCCCHHHCCCCCCHHHHHHHHCCHHEECCCCCCCCC
AIP
CCC
>Mature Secondary Structure 
TQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRV
CCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHH
TAQLHRQGNIINHKRVLRIMGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQ
HHHHHHCCCCCCHHHHHHEECCCCEEEEEEEEHEEECCCCCCCCEEEEEEHHEEHHCCCH
LWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDF
EEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
DELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAGDHAGVYSEGRRG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
FRRARFHLSAMTQAKKWHERQSSPATGNISARPGRSALGGLPSSRRMATIPYLCHFNESI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCEEECCHHEECCCCC
LGPQYAFSRHRGIYRSDVVQTTTNPGTGADLLPSLSPRSQAKERVGRTTLFSSSAMSSDP
CCCHHHHHHHCCCHHHHCEEECCCCCCCHHHCCCCCCHHHHHHHHCCHHEECCCCCCCCC
AIP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]