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The map label for this gene is iolC [H]

Identifier: 116620602

GI number: 116620602

Start: 1817351

End: 1818301

Strand: Direct

Name: iolC [H]

Synonym: Acid_1481

Alternate gene names: 116620602

Gene position: 1817351-1818301 (Clockwise)

Preceding gene: 116620601

Following gene: 116620603

Centisome position: 18.24

GC content: 63.72

Gene sequence:

>951_bases
ATGAGCGCGATGGACGTTGTAATTCTGGGCCGGATCGGGTACGACCTGTATTCGGAGGAGCCGCACGTGCCGCTGCCGCA
AGTGCGGAGATTCTCGCGGTATCTGGGTGGGTCGAGCGCCAACATGGCGGTGGGGCTCTCGCGATTGGGCGCGCGGGCGG
GCATGGTGAGTTGCCTGGGCGACGACAGCCTGAGCCGCTTCCTGGTTGATTTTCTGCAGGCGGAGAAAGTGGAGACGAGC
CACGTCAAGACGGCGCCCGGCTTTCTGCCCTCGCTGTGCCTGACCGAGGTATCGCCGCCGGACCGGTTCCCGCAGGTCTT
CTACCGGCGCGACCCGGTGGATACGATGCTGGACGCGACCGACGACGATTTGGACTATGCGGCATCGGGAACGATGTTCG
TCACCAACGGCACCACGCTGTGCGGATCGCCCTCGCGAGAATCGGCGTACCGTGCGTTGGAACGCGCGAAGAATGCGGGA
TGCCGGGTTGTGCTCGACGTGGACTACCGCTCGATGTCGTGGAGGAAGCCGGAAGAGGCGGGCCTCGCGGCGCGGCTAGC
GCTGCCATTCGTGGATGTGCTGATCGGCAACCAGCTGGAGTTGAAGCTGGTGGCTAACGTGGATGATCTGGATGAAGCGA
CCGGGAAACTGCAGGCGGCGGGAGTGCCGATGCTGGTTTCCAAATTAGGCGAACTGGGAACGCGAGTGCTCGCCGGCGGC
GAATCGGTGTACCTGCCGCCGTATTCGGTGGATGTGTGCACCACGATCGGCGCGGGCGACGGCTTCGCCAGCGGATTTCT
TTACGCGATGCTGAAGGGGCTTCCGGTGGCTGAATGCCTGCACTACGGCAATGCGGCGGCCGCGATTGTGGTGAGCCGGT
TGAGCTGCTCGGAGGCGATGCCGGTGCTGGCGGAAGTGGAAGAAATGATCCGGCAACAGAGAAAGGCATAA

Upstream 100 bases:

>100_bases
CGGGGTCGGCGCGCTCCATGGCAGCTTCCGACGATCCGGATTATGCGTGGGTGCGCGGCGCGTGGCGCGAGCAGGATCCG
CGATTGCCGATGGTGAAGCG

Downstream 100 bases:

>100_bases
GTGTTCGTCAGCAAAGACTATTTTCCCGACAGCCTGGTGGCGCGCCTGACCGAGACGCGGGTCAGCGATCCGGAGTTTGC
GTGGCGCGCCGCCCGCATGC

Product: ribokinase-like domain-containing protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSAMDVVILGRIGYDLYSEEPHVPLPQVRRFSRYLGGSSANMAVGLSRLGARAGMVSCLGDDSLSRFLVDFLQAEKVETS
HVKTAPGFLPSLCLTEVSPPDRFPQVFYRRDPVDTMLDATDDDLDYAASGTMFVTNGTTLCGSPSRESAYRALERAKNAG
CRVVLDVDYRSMSWRKPEEAGLAARLALPFVDVLIGNQLELKLVANVDDLDEATGKLQAAGVPMLVSKLGELGTRVLAGG
ESVYLPPYSVDVCTTIGAGDGFASGFLYAMLKGLPVAECLHYGNAAAAIVVSRLSCSEAMPVLAEVEEMIRQQRKA

Sequences:

>Translated_316_residues
MSAMDVVILGRIGYDLYSEEPHVPLPQVRRFSRYLGGSSANMAVGLSRLGARAGMVSCLGDDSLSRFLVDFLQAEKVETS
HVKTAPGFLPSLCLTEVSPPDRFPQVFYRRDPVDTMLDATDDDLDYAASGTMFVTNGTTLCGSPSRESAYRALERAKNAG
CRVVLDVDYRSMSWRKPEEAGLAARLALPFVDVLIGNQLELKLVANVDDLDEATGKLQAAGVPMLVSKLGELGTRVLAGG
ESVYLPPYSVDVCTTIGAGDGFASGFLYAMLKGLPVAECLHYGNAAAAIVVSRLSCSEAMPVLAEVEEMIRQQRKA
>Mature_315_residues
SAMDVVILGRIGYDLYSEEPHVPLPQVRRFSRYLGGSSANMAVGLSRLGARAGMVSCLGDDSLSRFLVDFLQAEKVETSH
VKTAPGFLPSLCLTEVSPPDRFPQVFYRRDPVDTMLDATDDDLDYAASGTMFVTNGTTLCGSPSRESAYRALERAKNAGC
RVVLDVDYRSMSWRKPEEAGLAARLALPFVDVLIGNQLELKLVANVDDLDEATGKLQAAGVPMLVSKLGELGTRVLAGGE
SVYLPPYSVDVCTTIGAGDGFASGFLYAMLKGLPVAECLHYGNAAAAIVVSRLSCSEAMPVLAEVEEMIRQQRKA

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=324, Percent_Identity=25.9259259259259, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082281, Length=292, Percent_Identity=23.972602739726, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790193, Length=345, Percent_Identity=23.4782608695652, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 33955; Mature: 33824

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAMDVVILGRIGYDLYSEEPHVPLPQVRRFSRYLGGSSANMAVGLSRLGARAGMVSCLG
CCCCEEEEEEHHCCHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
DDSLSRFLVDFLQAEKVETSHVKTAPGFLPSLCLTEVSPPDRFPQVFYRRDPVDTMLDAT
CHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHCCC
DDDLDYAASGTMFVTNGTTLCGSPSRESAYRALERAKNAGCRVVLDVDYRSMSWRKPEEA
CCCCCHHCCCCEEEECCCEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHH
GLAARLALPFVDVLIGNQLELKLVANVDDLDEATGKLQAAGVPMLVSKLGELGTRVLAGG
CHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHCCCHHCCHHHHHHHHHHHHHHEEECC
ESVYLPPYSVDVCTTIGAGDGFASGFLYAMLKGLPVAECLHYGNAAAAIVVSRLSCSEAM
CEEEECCCCCHHHEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHC
PVLAEVEEMIRQQRKA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAMDVVILGRIGYDLYSEEPHVPLPQVRRFSRYLGGSSANMAVGLSRLGARAGMVSCLG
CCCEEEEEEHHCCHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
DDSLSRFLVDFLQAEKVETSHVKTAPGFLPSLCLTEVSPPDRFPQVFYRRDPVDTMLDAT
CHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHCCC
DDDLDYAASGTMFVTNGTTLCGSPSRESAYRALERAKNAGCRVVLDVDYRSMSWRKPEEA
CCCCCHHCCCCEEEECCCEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHH
GLAARLALPFVDVLIGNQLELKLVANVDDLDEATGKLQAAGVPMLVSKLGELGTRVLAGG
CHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHCCCHHCCHHHHHHHHHHHHHHEEECC
ESVYLPPYSVDVCTTIGAGDGFASGFLYAMLKGLPVAECLHYGNAAAAIVVSRLSCSEAM
CEEEECCCCCHHHEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHC
PVLAEVEEMIRQQRKA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]