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The map label for this gene is lacD [H]

Identifier: 116620558

GI number: 116620558

Start: 1764359

End: 1765876

Strand: Direct

Name: lacD [H]

Synonym: Acid_1436

Alternate gene names: 116620558

Gene position: 1764359-1765876 (Clockwise)

Preceding gene: 116620557

Following gene: 116620561

Centisome position: 17.7

GC content: 60.67

Gene sequence:

>1518_bases
ATGCCGGAGTCTTTCCAGTTCGTGGATCCAGGCGAGCTTCAGGATGATGCCATCAGCCTGCAACTCGTGGCCACGCAACC
TGCCGATTCCACCAAGGGTTGGGTACCGTACTACGTCTTCCATATCCTCAGCCGCATAACTGGTCTCAGGGCTGGAGAAA
TCCACCTCCGAATTGGCTACACGGAGCATCTTCGCCTCTACGGCGGGCACGTTGCGTACGGCGTCCGTCCGGAGTACCGG
GGCCGCCACTTCGCAGGACGGGCTCTCCTGCTCGTGGTTCCCCTGGCCCGGCAACACGGCCTTTCTGAACTGTGGATCAC
CTGCAATCCCGAAAACGCTGCTTCTCGAAAAACCTGCGAGTTCGCAGGCGCCGAGTTCGTGGAAATTGTCGACTTGCCGC
CCCATACAGACATGTACCAGGAAGGTGAGCGGCAAAAGTGCCGTTACCGGTTGGATCTGTACACTCGCTCGCGCCCTGAT
AAACCAGCCCCGTGCCATAATCTACCCATGAAGCTATCCGACGGCAAATTGAAGCGCATGAAGGCGCTCTCGAACCAGCG
AGGCATCATCGCCGCCGCCGCCATGGACCAGCGCGGCAGCCTCCAGAAAGCTCTCGCCGGAGCCCGCGGTGTCGATGTCC
ACGAAATTACTCCCGCCATGATGAGCGAATTCAAGGTCGCCGTCACTCGCATCCTGACCCCACACGCCAGTGCCATTCTC
CTCGACCCCGAATTCGGCCTCGAGGCCGCCGCTGCCCGCGCGCCCAATGCCGGACTCCTCCTCGCTTACGAGCTCTCCGG
CTACGACAATACCCGCCCCGGCCGGCTCCCCGACCTGCTCCCTCACGTCTCTGTCAAGCGCATCGTCGATTGGGGCGCCG
ACGCTGTGAAGATTCTCATCTACTACTCTCCCTTTGATGATCCCGACGTGAAGGACATCAAACACGCCTTCATCGAACGC
ATCGGCGCCGAATGCGAGACCTACGAGATCCCCTTCTTCCTCGAATTCGTGGGTTACGATCCCAAGGGTGGCGACGAGCG
CGGCCTCGAATTCGCGCGCCAAAAGCCCGAGATCGTCAAGAAGAGCATGGAGGTCTTCTCCCGCCCCGAGTATCGCGTTG
ATGTGCTGAAAGTGGAAGTCCCCATCAACGCCGAGTTTGTGGAGGGCTCCGCGGTCTACAAAGGCCAGAAGGCCTATACC
CGCGAGGAAGCCCTCAAGCACTTTCGTGAGACTGCCGCCGTCGCCGGCAAGCCTTTCATCTATCTCTCCGCCGGAGTCAG
CAACGCGCAGTTTGTGGAATCCCTCGCCATGGCGTCCGAGGCGGGCACGGATTATTCCGGCGTCCTCTGCGGCCGCGCCA
CCTGGAAAGATGGCATCCCCATTTACGGCAAACAGGGCGTCAAGGCCCTGGAGGAGTGGCTGCAGCGCGAAGGCGTGCGC
AATATCAACGCCGTCAACGCAGCCATTCAGTCCGCGAAACCCTGGTGGACCAAGTTGGGAATTTCGATCAGCGCGTAA

Upstream 100 bases:

>100_bases
CACCGGCGTCGGCTACCTCGAAATGACCGGCTACGACAAGCCCATGAAGCTATAGGACAGGCCTCCCCGGGCTGTTGCTT
GCTGAATTAATATCAAGCTC

Downstream 100 bases:

>100_bases
GCAGGGGTCAGACCGCGCGCATGTACTGCGGCGCCAGGCCGATCATGACCATGCCGCAGAGCAGCAGCACCAGCATCAAG
ACGCCGAGTACCTTCACTCT

Product: tagatose-bisphosphate aldolase

Products: NA

Alternate protein names: D-tagatose-1,6-bisphosphate aldolase; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MPESFQFVDPGELQDDAISLQLVATQPADSTKGWVPYYVFHILSRITGLRAGEIHLRIGYTEHLRLYGGHVAYGVRPEYR
GRHFAGRALLLVVPLARQHGLSELWITCNPENAASRKTCEFAGAEFVEIVDLPPHTDMYQEGERQKCRYRLDLYTRSRPD
KPAPCHNLPMKLSDGKLKRMKALSNQRGIIAAAAMDQRGSLQKALAGARGVDVHEITPAMMSEFKVAVTRILTPHASAIL
LDPEFGLEAAAARAPNAGLLLAYELSGYDNTRPGRLPDLLPHVSVKRIVDWGADAVKILIYYSPFDDPDVKDIKHAFIER
IGAECETYEIPFFLEFVGYDPKGGDERGLEFARQKPEIVKKSMEVFSRPEYRVDVLKVEVPINAEFVEGSAVYKGQKAYT
REEALKHFRETAAVAGKPFIYLSAGVSNAQFVESLAMASEAGTDYSGVLCGRATWKDGIPIYGKQGVKALEEWLQREGVR
NINAVNAAIQSAKPWWTKLGISISA

Sequences:

>Translated_505_residues
MPESFQFVDPGELQDDAISLQLVATQPADSTKGWVPYYVFHILSRITGLRAGEIHLRIGYTEHLRLYGGHVAYGVRPEYR
GRHFAGRALLLVVPLARQHGLSELWITCNPENAASRKTCEFAGAEFVEIVDLPPHTDMYQEGERQKCRYRLDLYTRSRPD
KPAPCHNLPMKLSDGKLKRMKALSNQRGIIAAAAMDQRGSLQKALAGARGVDVHEITPAMMSEFKVAVTRILTPHASAIL
LDPEFGLEAAAARAPNAGLLLAYELSGYDNTRPGRLPDLLPHVSVKRIVDWGADAVKILIYYSPFDDPDVKDIKHAFIER
IGAECETYEIPFFLEFVGYDPKGGDERGLEFARQKPEIVKKSMEVFSRPEYRVDVLKVEVPINAEFVEGSAVYKGQKAYT
REEALKHFRETAAVAGKPFIYLSAGVSNAQFVESLAMASEAGTDYSGVLCGRATWKDGIPIYGKQGVKALEEWLQREGVR
NINAVNAAIQSAKPWWTKLGISISA
>Mature_504_residues
PESFQFVDPGELQDDAISLQLVATQPADSTKGWVPYYVFHILSRITGLRAGEIHLRIGYTEHLRLYGGHVAYGVRPEYRG
RHFAGRALLLVVPLARQHGLSELWITCNPENAASRKTCEFAGAEFVEIVDLPPHTDMYQEGERQKCRYRLDLYTRSRPDK
PAPCHNLPMKLSDGKLKRMKALSNQRGIIAAAAMDQRGSLQKALAGARGVDVHEITPAMMSEFKVAVTRILTPHASAILL
DPEFGLEAAAARAPNAGLLLAYELSGYDNTRPGRLPDLLPHVSVKRIVDWGADAVKILIYYSPFDDPDVKDIKHAFIERI
GAECETYEIPFFLEFVGYDPKGGDERGLEFARQKPEIVKKSMEVFSRPEYRVDVLKVEVPINAEFVEGSAVYKGQKAYTR
EEALKHFRETAAVAGKPFIYLSAGVSNAQFVESLAMASEAGTDYSGVLCGRATWKDGIPIYGKQGVKALEEWLQREGVRN
INAVNAAIQSAKPWWTKLGISISA

Specific function: Unknown

COG id: COG3684

COG function: function code G; Tagatose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase lacD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 56106; Mature: 55975

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESFQFVDPGELQDDAISLQLVATQPADSTKGWVPYYVFHILSRITGLRAGEIHLRIGY
CCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
TEHLRLYGGHVAYGVRPEYRGRHFAGRALLLVVPLARQHGLSELWITCNPENAASRKTCE
HHEEEEECCEEEECCCCCCCCCCCCCCEEEEEEECHHHCCCCEEEEEECCCCCCCCCHHH
FAGAEFVEIVDLPPHTDMYQEGERQKCRYRLDLYTRSRPDKPAPCHNLPMKLSDGKLKRM
HCCCCEEEEEECCCCCCHHHCCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
KALSNQRGIIAAAAMDQRGSLQKALAGARGVDVHEITPAMMSEFKVAVTRILTPHASAIL
HHHCCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEE
LDPEFGLEAAAARAPNAGLLLAYELSGYDNTRPGRLPDLLPHVSVKRIVDWGADAVKILI
ECCCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHCCHHHHHHHHCCCCEEEEEE
YYSPFDDPDVKDIKHAFIERIGAECETYEIPFFLEFVGYDPKGGDERGLEFARQKPEIVK
EECCCCCCCHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCHHHHHHHHCCHHHHH
KSMEVFSRPEYRVDVLKVEVPINAEFVEGSAVYKGQKAYTREEALKHFRETAAVAGKPFI
HHHHHHCCCCEEEEEEEEEECCCCEEECCCEEECCCHHHHHHHHHHHHHHHHHHCCCCEE
YLSAGVSNAQFVESLAMASEAGTDYSGVLCGRATWKDGIPIYGKQGVKALEEWLQREGVR
EEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
NINAVNAAIQSAKPWWTKLGISISA
CHHHHHHHHHCCCCCEEEECCEECC
>Mature Secondary Structure 
PESFQFVDPGELQDDAISLQLVATQPADSTKGWVPYYVFHILSRITGLRAGEIHLRIGY
CCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
TEHLRLYGGHVAYGVRPEYRGRHFAGRALLLVVPLARQHGLSELWITCNPENAASRKTCE
HHEEEEECCEEEECCCCCCCCCCCCCCEEEEEEECHHHCCCCEEEEEECCCCCCCCCHHH
FAGAEFVEIVDLPPHTDMYQEGERQKCRYRLDLYTRSRPDKPAPCHNLPMKLSDGKLKRM
HCCCCEEEEEECCCCCCHHHCCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
KALSNQRGIIAAAAMDQRGSLQKALAGARGVDVHEITPAMMSEFKVAVTRILTPHASAIL
HHHCCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCEEE
LDPEFGLEAAAARAPNAGLLLAYELSGYDNTRPGRLPDLLPHVSVKRIVDWGADAVKILI
ECCCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHCCHHHHHHHHCCCCEEEEEE
YYSPFDDPDVKDIKHAFIERIGAECETYEIPFFLEFVGYDPKGGDERGLEFARQKPEIVK
EECCCCCCCHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCCCHHHHHHHHCCHHHHH
KSMEVFSRPEYRVDVLKVEVPINAEFVEGSAVYKGQKAYTREEALKHFRETAAVAGKPFI
HHHHHHCCCCEEEEEEEEEECCCCEEECCCEEECCCHHHHHHHHHHHHHHHHHHCCCCEE
YLSAGVSNAQFVESLAMASEAGTDYSGVLCGRATWKDGIPIYGKQGVKALEEWLQREGVR
EEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
NINAVNAAIQSAKPWWTKLGISISA
CHHHHHHHHHCCCCCEEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]