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The map label for this gene is flp [H]

Identifier: 116620436

GI number: 116620436

Start: 1623777

End: 1624805

Strand: Direct

Name: flp [H]

Synonym: Acid_1314

Alternate gene names: 116620436

Gene position: 1623777-1624805 (Clockwise)

Preceding gene: 116620435

Following gene: 116620439

Centisome position: 16.29

GC content: 65.11

Gene sequence:

>1029_bases
ATGAAGCTTCGTGCTCTTGCGGTTGCCATTCTGCCAGCGCTGCTGTGCGGTGCGGACCTGGATTCCACTATCGCCGAACG
CATGCAGGCATTGAAGGTGCCGGCGGTGAGCGTGGCCGTGCTCGATGGCGGCAAACCGTTATGGGCTCGCGGGTATGGCG
CCGGCGTCAATGCCGAGACCGTCTTTCAGGCGGCTTCGCTGAGTAAGCACGTTGCCGCGCTGATCGCGCTGCGGCTGGCA
GACGAGGGCAAGCTCTCGCTGGACGAGGACGTCAACCGCAAGCTGCGCACCTGGAAGATCCCGGAGAACGAATTTACCAA
GACCGAAAAGGTCACGCTGCGGCGCCTGCTCAATCACAGCGCGGGACTTACGGTGCACGGCTTTGCGGGCTATGCGAGCG
GTACGCCGGTGCCTTCGCTGATCCAGGTGCTGGATGGCGTGAGGCCGGCCAACTCCCAGGCGGTGCGGGTGGACATGGTG
CCGGGGAGCCAGTGGCGCTACTCGGGGGGCGGGTACGAGGTGGTGCAGCAGTTGATCCTCGACGTCACCGGCAGGTCCTT
CGCGGACCTGGCACGGACCTTGATCTTCGAGCCGCTCGGCATGAAGCGCAGCACCTTCGAGCAGCCCCTGCCCGCCGGGT
GGGAGGGTAACGCCGCGATCGGGCATCGACCTGACGGGACGATGCTGCCGGGGCGCTGGCACACCTATCCCGAGCTGGCG
GCGGCGGGCCTCTGGACCACCCCTTCCGACCTGACCAGGATCATTCTTGAAATCCAGGCGGGCGGCGGGCGGATCCTCAA
GCCGGCGACCCAGAAGCAGATGCTCACCCGGCTGTTGGGGAATTACGGCCTGGGGCTCGGAATCGAAGACAAAGCCTTCT
CCCACGGCGGCGCTAACGAGGGATTCCGGTGTTCGATGATTGGCTACCTGACGGGTGGAAGAGGAATCGTGGTGATGACG
AACAGCGATAGCGGGAGCCGTCTGGCGACGGAGATTCAGCGGAAGATTGCCGCTGACCGCGGCTGGTAG

Upstream 100 bases:

>100_bases
CGGCGGAGATGCGTCGCAGATCAGCTCTTGCGACGTCACGCTTGCCAACTCGGCGGGCACCACCATACAACGGATCGCGA
CATTCAGTATCCTGTAACGC

Downstream 100 bases:

>100_bases
AAGGATGCGGGCCGGGAAGGAACCCGGCCCGCGGAATCGGACTAGGCGTTGGCGCGCAGCCATTCACGGAAGGCTTCGCG
ATAGAGCACAATGCCTTTAC

Product: beta-lactamase

Products: substituted beta-amino acid

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKLRALAVAILPALLCGADLDSTIAERMQALKVPAVSVAVLDGGKPLWARGYGAGVNAETVFQAASLSKHVAALIALRLA
DEGKLSLDEDVNRKLRTWKIPENEFTKTEKVTLRRLLNHSAGLTVHGFAGYASGTPVPSLIQVLDGVRPANSQAVRVDMV
PGSQWRYSGGGYEVVQQLILDVTGRSFADLARTLIFEPLGMKRSTFEQPLPAGWEGNAAIGHRPDGTMLPGRWHTYPELA
AAGLWTTPSDLTRIILEIQAGGGRILKPATQKQMLTRLLGNYGLGLGIEDKAFSHGGANEGFRCSMIGYLTGGRGIVVMT
NSDSGSRLATEIQRKIAADRGW

Sequences:

>Translated_342_residues
MKLRALAVAILPALLCGADLDSTIAERMQALKVPAVSVAVLDGGKPLWARGYGAGVNAETVFQAASLSKHVAALIALRLA
DEGKLSLDEDVNRKLRTWKIPENEFTKTEKVTLRRLLNHSAGLTVHGFAGYASGTPVPSLIQVLDGVRPANSQAVRVDMV
PGSQWRYSGGGYEVVQQLILDVTGRSFADLARTLIFEPLGMKRSTFEQPLPAGWEGNAAIGHRPDGTMLPGRWHTYPELA
AAGLWTTPSDLTRIILEIQAGGGRILKPATQKQMLTRLLGNYGLGLGIEDKAFSHGGANEGFRCSMIGYLTGGRGIVVMT
NSDSGSRLATEIQRKIAADRGW
>Mature_342_residues
MKLRALAVAILPALLCGADLDSTIAERMQALKVPAVSVAVLDGGKPLWARGYGAGVNAETVFQAASLSKHVAALIALRLA
DEGKLSLDEDVNRKLRTWKIPENEFTKTEKVTLRRLLNHSAGLTVHGFAGYASGTPVPSLIQVLDGVRPANSQAVRVDMV
PGSQWRYSGGGYEVVQQLILDVTGRSFADLARTLIFEPLGMKRSTFEQPLPAGWEGNAAIGHRPDGTMLPGRWHTYPELA
AAGLWTTPSDLTRIILEIQAGGGRILKPATQKQMLTRLLGNYGLGLGIEDKAFSHGGANEGFRCSMIGYLTGGRGIVVMT
NSDSGSRLATEIQRKIAADRGW

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI115533026, Length=249, Percent_Identity=27.3092369477912, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6

Molecular weight: Translated: 36679; Mature: 36679

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRALAVAILPALLCGADLDSTIAERMQALKVPAVSVAVLDGGKPLWARGYGAGVNAET
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCHHH
VFQAASLSKHVAALIALRLADEGKLSLDEDVNRKLRTWKIPENEFTKTEKVTLRRLLNHS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHEEECCCHHHHHHHHHHHHHHHCCC
AGLTVHGFAGYASGTPVPSLIQVLDGVRPANSQAVRVDMVPGSQWRYSGGGYEVVQQLIL
CCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHH
DVTGRSFADLARTLIFEPLGMKRSTFEQPLPAGWEGNAAIGHRPDGTMLPGRWHTYPELA
HHCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AAGLWTTPSDLTRIILEIQAGGGRILKPATQKQMLTRLLGNYGLGLGIEDKAFSHGGANE
HCCCCCCHHHHEEEEEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCC
GFRCSMIGYLTGGRGIVVMTNSDSGSRLATEIQRKIAADRGW
CEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLRALAVAILPALLCGADLDSTIAERMQALKVPAVSVAVLDGGKPLWARGYGAGVNAET
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCHHH
VFQAASLSKHVAALIALRLADEGKLSLDEDVNRKLRTWKIPENEFTKTEKVTLRRLLNHS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHEEECCCHHHHHHHHHHHHHHHCCC
AGLTVHGFAGYASGTPVPSLIQVLDGVRPANSQAVRVDMVPGSQWRYSGGGYEVVQQLIL
CCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHH
DVTGRSFADLARTLIFEPLGMKRSTFEQPLPAGWEGNAAIGHRPDGTMLPGRWHTYPELA
HHCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AAGLWTTPSDLTRIILEIQAGGGRILKPATQKQMLTRLLGNYGLGLGIEDKAFSHGGANE
HCCCCCCHHHHEEEEEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCC
GFRCSMIGYLTGGRGIVVMTNSDSGSRLATEIQRKIAADRGW
CEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-lactam; H2O

Specific reaction: A beta-lactam + H2O = a substituted beta-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA