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The map label for this gene is sigW [H]

Identifier: 116620358

GI number: 116620358

Start: 1527240

End: 1527815

Strand: Direct

Name: sigW [H]

Synonym: Acid_1235

Alternate gene names: 116620358

Gene position: 1527240-1527815 (Clockwise)

Preceding gene: 116620350

Following gene: 116620359

Centisome position: 15.33

GC content: 61.11

Gene sequence:

>576_bases
ATGCCCGTTGAAGCCATGCCGATCAGCCAACCAGAAGAGAGTGAGGCTGAGCGAATCGCACGTGGGCTACGGCGGAAAGA
CCTTACTTTAGTCCGGGAGTTAGTCGAGCGTTATCAATACCGGCTCGTGCGCTATTTGATTTTTCTAACCGCACGGCGCG
AATTTGCAGAAGATTGGGCGCAGGAGACGTGGGTGCGTGTTCTCGACCGCGCGTCGCAGTACGATGGCCGATCGCGCTTC
GAAGCATGGCTCTTCTCGATTGCGCGGAATCTGGCAATCGACGACCTGCGTCGGCGGCAGAACGTTAGCCTGGAGGCGGC
AAACGAAGAACCGCTCGACCCCACCTCGCCGTTCGTGACGGCTGCCCGAAACGAGGAGGCGGCCCGGCTCGCTGCCGCGC
TCGGAACGTTGGAGCCGATTTACCGCGAGGCCCTACTGTTGCGATTTCACGAGGATCTGTCCCTTCAGGAGATTAGCCAT
CTCGTCGGAGCACCCGTGCCGACTGTGGCGTCGCGGATTCGTCGCGGATTGGAGCGCTTGCGGCTGCACTGGGAAAGAGG
AGCGGATGGGGCCTGA

Upstream 100 bases:

>100_bases
GGTGTAGGAGGAAGCCACCGGTTCCCGCGTGATTCCGGAACCGGGCATGCGATCGCGGCAATGCATAATTCTGAAGCCCT
GATCCGTATACCCTGTGTGT

Downstream 100 bases:

>100_bases
TCCACATCAGCGAGCCCGGTTTTTGGTGGGGGAGGCCCGGATAGCGGGAATCGCGCTTCAGGACGCGCTCTGGCTGCAAA
GCCACGTGGCAGAGTGCACT

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MPVEAMPISQPEESEAERIARGLRRKDLTLVRELVERYQYRLVRYLIFLTARREFAEDWAQETWVRVLDRASQYDGRSRF
EAWLFSIARNLAIDDLRRRQNVSLEAANEEPLDPTSPFVTAARNEEAARLAAALGTLEPIYREALLLRFHEDLSLQEISH
LVGAPVPTVASRIRRGLERLRLHWERGADGA

Sequences:

>Translated_191_residues
MPVEAMPISQPEESEAERIARGLRRKDLTLVRELVERYQYRLVRYLIFLTARREFAEDWAQETWVRVLDRASQYDGRSRF
EAWLFSIARNLAIDDLRRRQNVSLEAANEEPLDPTSPFVTAARNEEAARLAAALGTLEPIYREALLLRFHEDLSLQEISH
LVGAPVPTVASRIRRGLERLRLHWERGADGA
>Mature_190_residues
PVEAMPISQPEESEAERIARGLRRKDLTLVRELVERYQYRLVRYLIFLTARREFAEDWAQETWVRVLDRASQYDGRSRFE
AWLFSIARNLAIDDLRRRQNVSLEAANEEPLDPTSPFVTAARNEEAARLAAALGTLEPIYREALLLRFHEDLSLQEISHL
VGAPVPTVASRIRRGLERLRLHWERGADGA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22121; Mature: 21990

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVEAMPISQPEESEAERIARGLRRKDLTLVRELVERYQYRLVRYLIFLTARREFAEDWA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QETWVRVLDRASQYDGRSRFEAWLFSIARNLAIDDLRRRQNVSLEAANEEPLDPTSPFVT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AARNEEAARLAAALGTLEPIYREALLLRFHEDLSLQEISHLVGAPVPTVASRIRRGLERL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
RLHWERGADGA
HHHHHCCCCCC
>Mature Secondary Structure 
PVEAMPISQPEESEAERIARGLRRKDLTLVRELVERYQYRLVRYLIFLTARREFAEDWA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QETWVRVLDRASQYDGRSRFEAWLFSIARNLAIDDLRRRQNVSLEAANEEPLDPTSPFVT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AARNEEAARLAAALGTLEPIYREALLLRFHEDLSLQEISHLVGAPVPTVASRIRRGLERL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
RLHWERGADGA
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]