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The map label for this gene is sglT [H]

Identifier: 116620356

GI number: 116620356

Start: 1524049

End: 1525773

Strand: Reverse

Name: sglT [H]

Synonym: Acid_1233

Alternate gene names: 116620356

Gene position: 1525773-1524049 (Counterclockwise)

Preceding gene: 116620357

Following gene: 116620355

Centisome position: 15.31

GC content: 61.39

Gene sequence:

>1725_bases
ATGCAGGTGCAAGCGATTACAGCATTCTCCCCGGCGTTGCTGCTGCAAGCGCAGCTGATGACGCTCTCCACGGTTGACTT
GGCGATCATCGTCCTCTACTTCGCGGCCGTGCTCGGGATTGGCTTCTACCTTAAACGGTTCACCAAGACCGGCGAAGATT
TCTTCCTCGCCGGCCGCGAAATGACCGCCTGGATCGCCGGCCTCAGTTTCCTCGCCGCCAACCTCGGCTCGCTCGAGCTC
ATGGGCTGGGCCGCCTCCGCCTATCAATACGGCATCCTCGCCACGCACTGGTATTGGATCGGCGCCATCCCCGCGATGCT
CTTCCTGGGCATCGTCATGATCCCGTTCTATTACATTTCCAAGACGCACTCCGTCCCCGGCTACCTCAAGCTCCGCTTCG
GCGAACCCGCCCGCGCTCTCTCGGCAATCTCCTTTGGGTTGATGACCGTGTTCATGAGCGGCATCAATATGTACTCCATG
GCCCTGGTCATGAAGGTCGTGCTCGGCTGGGACATCCACGTCAGCATCTGGATCTCTTCCATTACGGTCATGCTCTACGT
CGGCCTCGGCGGCCTGCTCTCCGCCATCTTCAATGAGGTGCTGCAGTTCGTCCTCATCTGGCTCGGCGCGATGCTGATCT
CCATCATCGGCCTGATCGAAGCCGGCGGCTGGGACGGCATGGTGGCCAAGATCCACGCCAACTTCCCGCAAGGCGATTAC
ACCCACGCCTGGCGCACCCTCGGCTCCTTCAACGACAACCCGATGGGGATCAACTGGGTCGGGATCGTGTTCGGCCTCGG
CGCCGTAATCTCCATGGGCTACTGGACCACGGATTTCCTGGTCGTGCAGCGCGTAATCTCCGCCAAAGATCTGCGCGCCG
CGAAACTTGCCCCCATCATCGGCGCCGCCTTCAAGATGTGCGTGCCTTTCATCGTCATCCTGCCCGGCCTGCTCGGTCTC
GCTGTGCTGCCCGAGCACCTGCTCCCCGAAAGCCAGGCGCTCGCCACCGGCGGCCACAGCTATAACGAAGTGCTGCCGAT
CATGCTCGCGCGCTACTGCGGCCCCGGCTTGCTCGGACTCGGCATCACCGCCCTCATCGCCGGCTTCATGAGCGGCATGG
CCGGCAACGTCAGCGCCTTCGCCACCGTCTGGACCTACGACGTCTACCGCGCCATGTTCAACAAGAACGCCACCGATTCG
CACTATGTCAGCGTGGGCCGCTGGTGCACCTTCTGGGGCGTGCTCGCCTCCATCGGCACCGCGTATATGGTGATGAGTTT
CGCCAGCATCATGGATTACGTCCAGGCTCTCTTCAGTTTCTTCATCGCCCCCTTATTCGGCACCGTCATTCTCGGCATGT
TGTGGAAGCGCGCCTCCCCCGCCGGCGGCTTCTGGGGCCTTGCGGCCGGCACCGCGAGTTCGATCGGCATGTGGGCCTGG
GTGAAAATCGATCACACCGCCATTCAATATGTAGCCATGTCGCCCAACGCAAAGGACATGGCGGAGAATATGTTCCGCGC
CCTCTGGTCCTGGCTGGTGTGCGTCATCGTCACCGTCGTTGTCAGCCTCATGACCAAGCCCAAACCCGAAAAGGAACTGG
TCAACCTGGTCTATGGCTGCACCGACATTCCGTCGGAAGGCCACCTGCCGGTATGGCAGCGCCCCGCTTTCTGGGCCTGC
GTCGTGGGCGCGGTTTTTATCGCTCTGAATATTATTTTCTGGTAG

Upstream 100 bases:

>100_bases
GATCGACCCGGAGTTTGTTTTGCGCGATTCCACGGGCCCCGCGCCCGTGCGCTGAGACGCCTAGTGCGTCCTTGACACGA
AAGTTGAGGCCCCATACTAT

Downstream 100 bases:

>100_bases
TCGGAAAGGCACATACGCAATGAATAACGGCAAGTCCCGTCCTGTTACATTCGGCATGATCGTGGGCAACCGCGGATTCT
TCCCGGACCACCTGGCCAAG

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MQVQAITAFSPALLLQAQLMTLSTVDLAIIVLYFAAVLGIGFYLKRFTKTGEDFFLAGREMTAWIAGLSFLAANLGSLEL
MGWAASAYQYGILATHWYWIGAIPAMLFLGIVMIPFYYISKTHSVPGYLKLRFGEPARALSAISFGLMTVFMSGINMYSM
ALVMKVVLGWDIHVSIWISSITVMLYVGLGGLLSAIFNEVLQFVLIWLGAMLISIIGLIEAGGWDGMVAKIHANFPQGDY
THAWRTLGSFNDNPMGINWVGIVFGLGAVISMGYWTTDFLVVQRVISAKDLRAAKLAPIIGAAFKMCVPFIVILPGLLGL
AVLPEHLLPESQALATGGHSYNEVLPIMLARYCGPGLLGLGITALIAGFMSGMAGNVSAFATVWTYDVYRAMFNKNATDS
HYVSVGRWCTFWGVLASIGTAYMVMSFASIMDYVQALFSFFIAPLFGTVILGMLWKRASPAGGFWGLAAGTASSIGMWAW
VKIDHTAIQYVAMSPNAKDMAENMFRALWSWLVCVIVTVVVSLMTKPKPEKELVNLVYGCTDIPSEGHLPVWQRPAFWAC
VVGAVFIALNIIFW

Sequences:

>Translated_574_residues
MQVQAITAFSPALLLQAQLMTLSTVDLAIIVLYFAAVLGIGFYLKRFTKTGEDFFLAGREMTAWIAGLSFLAANLGSLEL
MGWAASAYQYGILATHWYWIGAIPAMLFLGIVMIPFYYISKTHSVPGYLKLRFGEPARALSAISFGLMTVFMSGINMYSM
ALVMKVVLGWDIHVSIWISSITVMLYVGLGGLLSAIFNEVLQFVLIWLGAMLISIIGLIEAGGWDGMVAKIHANFPQGDY
THAWRTLGSFNDNPMGINWVGIVFGLGAVISMGYWTTDFLVVQRVISAKDLRAAKLAPIIGAAFKMCVPFIVILPGLLGL
AVLPEHLLPESQALATGGHSYNEVLPIMLARYCGPGLLGLGITALIAGFMSGMAGNVSAFATVWTYDVYRAMFNKNATDS
HYVSVGRWCTFWGVLASIGTAYMVMSFASIMDYVQALFSFFIAPLFGTVILGMLWKRASPAGGFWGLAAGTASSIGMWAW
VKIDHTAIQYVAMSPNAKDMAENMFRALWSWLVCVIVTVVVSLMTKPKPEKELVNLVYGCTDIPSEGHLPVWQRPAFWAC
VVGAVFIALNIIFW
>Mature_574_residues
MQVQAITAFSPALLLQAQLMTLSTVDLAIIVLYFAAVLGIGFYLKRFTKTGEDFFLAGREMTAWIAGLSFLAANLGSLEL
MGWAASAYQYGILATHWYWIGAIPAMLFLGIVMIPFYYISKTHSVPGYLKLRFGEPARALSAISFGLMTVFMSGINMYSM
ALVMKVVLGWDIHVSIWISSITVMLYVGLGGLLSAIFNEVLQFVLIWLGAMLISIIGLIEAGGWDGMVAKIHANFPQGDY
THAWRTLGSFNDNPMGINWVGIVFGLGAVISMGYWTTDFLVVQRVISAKDLRAAKLAPIIGAAFKMCVPFIVILPGLLGL
AVLPEHLLPESQALATGGHSYNEVLPIMLARYCGPGLLGLGITALIAGFMSGMAGNVSAFATVWTYDVYRAMFNKNATDS
HYVSVGRWCTFWGVLASIGTAYMVMSFASIMDYVQALFSFFIAPLFGTVILGMLWKRASPAGGFWGLAAGTASSIGMWAW
VKIDHTAIQYVAMSPNAKDMAENMFRALWSWLVCVIVTVVVSLMTKPKPEKELVNLVYGCTDIPSEGHLPVWQRPAFWAC
VVGAVFIALNIIFW

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=538, Percent_Identity=27.1375464684015, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI110835708, Length=554, Percent_Identity=28.7003610108303, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI4507031, Length=558, Percent_Identity=26.7025089605735, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI109659836, Length=599, Percent_Identity=26.2103505843072, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI206597483, Length=533, Percent_Identity=28.1425891181989, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI109659839, Length=615, Percent_Identity=26.0162601626016, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI206597487, Length=557, Percent_Identity=26.9299820466786, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI17941285, Length=558, Percent_Identity=26.1648745519713, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI4507033, Length=581, Percent_Identity=24.9569707401033, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI256985183, Length=493, Percent_Identity=25.5578093306288, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI157671931, Length=462, Percent_Identity=23.8095238095238, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI167466278, Length=454, Percent_Identity=26.8722466960352, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4507035, Length=463, Percent_Identity=23.9740820734341, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310128183, Length=520, Percent_Identity=24.0384615384615, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790113, Length=461, Percent_Identity=26.0303687635575, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787251, Length=398, Percent_Identity=24.1206030150754, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082237, Length=377, Percent_Identity=23.6074270557029, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573698, Length=465, Percent_Identity=24.7311827956989, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24641117, Length=467, Percent_Identity=25.2676659528908, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24651739, Length=518, Percent_Identity=21.042471042471, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281362918, Length=587, Percent_Identity=22.1465076660988, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221459584, Length=425, Percent_Identity=23.2941176470588, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24645928, Length=462, Percent_Identity=24.025974025974, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI221459582, Length=442, Percent_Identity=23.5294117647059, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24651741, Length=480, Percent_Identity=20.2083333333333, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221459586, Length=433, Percent_Identity=23.3256351039261, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574994, Length=462, Percent_Identity=21.8614718614719, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281362054, Length=444, Percent_Identity=22.0720720720721, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362052, Length=444, Percent_Identity=22.0720720720721, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362050, Length=444, Percent_Identity=22.0720720720721, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648056, Length=444, Percent_Identity=22.0720720720721, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356827, Length=444, Percent_Identity=22.0720720720721, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221459588, Length=442, Percent_Identity=23.3031674208145, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650192, Length=379, Percent_Identity=22.4274406332454, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 62640; Mature: 62640

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVQAITAFSPALLLQAQLMTLSTVDLAIIVLYFAAVLGIGFYLKRFTKTGEDFFLAGRE
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECHH
MTAWIAGLSFLAANLGSLELMGWAASAYQYGILATHWYWIGAIPAMLFLGIVMIPFYYIS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTHSVPGYLKLRFGEPARALSAISFGLMTVFMSGINMYSMALVMKVVLGWDIHVSIWISS
HCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ITVMLYVGLGGLLSAIFNEVLQFVLIWLGAMLISIIGLIEAGGWDGMVAKIHANFPQGDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCH
THAWRTLGSFNDNPMGINWVGIVFGLGAVISMGYWTTDFLVVQRVISAKDLRAAKLAPII
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAFKMCVPFIVILPGLLGLAVLPEHLLPESQALATGGHSYNEVLPIMLARYCGPGLLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCCHHHH
GITALIAGFMSGMAGNVSAFATVWTYDVYRAMFNKNATDSHYVSVGRWCTFWGVLASIGT
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AYMVMSFASIMDYVQALFSFFIAPLFGTVILGMLWKRASPAGGFWGLAAGTASSIGMWAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEE
VKIDHTAIQYVAMSPNAKDMAENMFRALWSWLVCVIVTVVVSLMTKPKPEKELVNLVYGC
EEEEHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
TDIPSEGHLPVWQRPAFWACVVGAVFIALNIIFW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQVQAITAFSPALLLQAQLMTLSTVDLAIIVLYFAAVLGIGFYLKRFTKTGEDFFLAGRE
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECHH
MTAWIAGLSFLAANLGSLELMGWAASAYQYGILATHWYWIGAIPAMLFLGIVMIPFYYIS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTHSVPGYLKLRFGEPARALSAISFGLMTVFMSGINMYSMALVMKVVLGWDIHVSIWISS
HCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ITVMLYVGLGGLLSAIFNEVLQFVLIWLGAMLISIIGLIEAGGWDGMVAKIHANFPQGDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCH
THAWRTLGSFNDNPMGINWVGIVFGLGAVISMGYWTTDFLVVQRVISAKDLRAAKLAPII
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAFKMCVPFIVILPGLLGLAVLPEHLLPESQALATGGHSYNEVLPIMLARYCGPGLLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCCHHHH
GITALIAGFMSGMAGNVSAFATVWTYDVYRAMFNKNATDSHYVSVGRWCTFWGVLASIGT
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
AYMVMSFASIMDYVQALFSFFIAPLFGTVILGMLWKRASPAGGFWGLAAGTASSIGMWAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEE
VKIDHTAIQYVAMSPNAKDMAENMFRALWSWLVCVIVTVVVSLMTKPKPEKELVNLVYGC
EEEEHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
TDIPSEGHLPVWQRPAFWACVVGAVFIALNIIFW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]