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The map label for this gene is etfA [H]

Identifier: 116620288

GI number: 116620288

Start: 1434874

End: 1435848

Strand: Reverse

Name: etfA [H]

Synonym: Acid_1165

Alternate gene names: 116620288

Gene position: 1435848-1434874 (Counterclockwise)

Preceding gene: 116620289

Following gene: 116620287

Centisome position: 14.41

GC content: 63.08

Gene sequence:

>975_bases
ATGAGCATCCTGGTTGTGATGGAGCAGCGTGCGGGCGAGTGGAACCGCATGTCGTTTGAGACCCTGGCCGCCGCACAGCA
GTTCGCGCGAGAGCTTGGCACTACCGCGTCCGCGGCGATTCTCGGGCAGGGTCTCGATGGACTCGCCGCCGAACTGGCCG
GTAAACAGCTCGACAAGGTCTATGTGGTGGAGCACGAATTGTTGAGGGAGTACACGGCCGACGCCTGGTCGAGCGCCCTC
CGCCAATTGGTCGCCCAGGTTAGGCCGACCTACGTTTTGTTTCCGCACACGTACCAGGTCCGCGACTTCCTTCCGAAGCT
CGCTACCGCGATGGGGAAGGTTGCGGTGAACGATGTGGTGGGGCATCGCGCGGAAGGCGGCGGACTGGTGTTGGTGCGCC
AGCTTTTCCAGGGCAAGGTGAATGTGGATGTGCGCTTCGCCGGTGAAGCGCCGCACTTCGCATCGCTGCAGGCCGGCGCC
TGGCGCGCCGACCAGCTGGCTGCCGGCTCGGCCGCCATCGAGAAGTTCAGCGCCGCGATCGCAGCCTCCGATATCCGCAG
CAAGCCGCAGGAGCGCTTCCGCGAATCGGCGCGCGCAGTGGATCTCACCGCTGCCGAACTGATCGTCGCGGTTGGCCGCG
GGATCAAGGAAGCCGATAACATTCCGATCGTCCAGGAATTGGCCGATGTCCTGGGCGCGGAGCTCGCGGCGTCGCGACCG
ATTTGTGACGCGGGCTGGCTCCCGATGGAGCGGCAGGTGGGCAGCTCGGGCCAGACGGTCGGGCCAAAAATGTACATGGC
GATCGGAATCTCCGGTGCGATTCAGCACCTTGTAGGAATGAAGGGTGCGCGCACTATCGTGGCGATTAATAAGGACCCGA
ATGCTCCGATATTCGAAGTCGCCGATTACGGGATCGTGGGCGATCTTTTCCAGATTGTCCCGGCCCTGGTGGACGCATTT
AAGAAGGTGAAGTAA

Upstream 100 bases:

>100_bases
ACCTGCCGGAGCGCGCCAAGCAAACCCAGCTTTTCGACGGACCCCCGGCGGAGGCTGCAGCCAAACTGGTGGAGAAATTG
AAATTCGAGGCGCGGGTCAT

Downstream 100 bases:

>100_bases
TCCAGATCGCTCCCTGACGGTCGCGGTCCGCGAAGTACTTTGTAATGTTATGTAAATCCGGTCAACGATTTGACACTGAG
CCCGTCATATAGGTATACTT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSILVVMEQRAGEWNRMSFETLAAAQQFARELGTTASAAILGQGLDGLAAELAGKQLDKVYVVEHELLREYTADAWSSAL
RQLVAQVRPTYVLFPHTYQVRDFLPKLATAMGKVAVNDVVGHRAEGGGLVLVRQLFQGKVNVDVRFAGEAPHFASLQAGA
WRADQLAAGSAAIEKFSAAIAASDIRSKPQERFRESARAVDLTAAELIVAVGRGIKEADNIPIVQELADVLGAELAASRP
ICDAGWLPMERQVGSSGQTVGPKMYMAIGISGAIQHLVGMKGARTIVAINKDPNAPIFEVADYGIVGDLFQIVPALVDAF
KKVK

Sequences:

>Translated_324_residues
MSILVVMEQRAGEWNRMSFETLAAAQQFARELGTTASAAILGQGLDGLAAELAGKQLDKVYVVEHELLREYTADAWSSAL
RQLVAQVRPTYVLFPHTYQVRDFLPKLATAMGKVAVNDVVGHRAEGGGLVLVRQLFQGKVNVDVRFAGEAPHFASLQAGA
WRADQLAAGSAAIEKFSAAIAASDIRSKPQERFRESARAVDLTAAELIVAVGRGIKEADNIPIVQELADVLGAELAASRP
ICDAGWLPMERQVGSSGQTVGPKMYMAIGISGAIQHLVGMKGARTIVAINKDPNAPIFEVADYGIVGDLFQIVPALVDAF
KKVK
>Mature_323_residues
SILVVMEQRAGEWNRMSFETLAAAQQFARELGTTASAAILGQGLDGLAAELAGKQLDKVYVVEHELLREYTADAWSSALR
QLVAQVRPTYVLFPHTYQVRDFLPKLATAMGKVAVNDVVGHRAEGGGLVLVRQLFQGKVNVDVRFAGEAPHFASLQAGAW
RADQLAAGSAAIEKFSAAIAASDIRSKPQERFRESARAVDLTAAELIVAVGRGIKEADNIPIVQELADVLGAELAASRPI
CDAGWLPMERQVGSSGQTVGPKMYMAIGISGAIQHLVGMKGARTIVAINKDPNAPIFEVADYGIVGDLFQIVPALVDAFK
KVK

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=322, Percent_Identity=33.5403726708075, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI189181759, Length=264, Percent_Identity=35.6060606060606, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1787990, Length=134, Percent_Identity=49.2537313432836, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786226, Length=237, Percent_Identity=37.1308016877637, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87082157, Length=166, Percent_Identity=31.3253012048193, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=322, Percent_Identity=33.2298136645963, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6325261, Length=125, Percent_Identity=48, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136898, Length=316, Percent_Identity=32.5949367088608, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24652801, Length=316, Percent_Identity=32.5949367088608, Blast_Score=171, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 34661; Mature: 34530

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVVMEQRAGEWNRMSFETLAAAQQFARELGTTASAAILGQGLDGLAAELAGKQLDKV
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHH
YVVEHELLREYTADAWSSALRQLVAQVRPTYVLFPHTYQVRDFLPKLATAMGKVAVNDVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GHRAEGGGLVLVRQLFQGKVNVDVRFAGEAPHFASLQAGAWRADQLAAGSAAIEKFSAAI
CCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
AASDIRSKPQERFRESARAVDLTAAELIVAVGRGIKEADNIPIVQELADVLGAELAASRP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC
ICDAGWLPMERQVGSSGQTVGPKMYMAIGISGAIQHLVGMKGARTIVAINKDPNAPIFEV
CCCCCCCCHHHHCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCEEEEECCCCCCCEEHH
ADYGIVGDLFQIVPALVDAFKKVK
HCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILVVMEQRAGEWNRMSFETLAAAQQFARELGTTASAAILGQGLDGLAAELAGKQLDKV
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHH
YVVEHELLREYTADAWSSALRQLVAQVRPTYVLFPHTYQVRDFLPKLATAMGKVAVNDVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GHRAEGGGLVLVRQLFQGKVNVDVRFAGEAPHFASLQAGAWRADQLAAGSAAIEKFSAAI
CCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
AASDIRSKPQERFRESARAVDLTAAELIVAVGRGIKEADNIPIVQELADVLGAELAASRP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC
ICDAGWLPMERQVGSSGQTVGPKMYMAIGISGAIQHLVGMKGARTIVAINKDPNAPIFEV
CCCCCCCCHHHHCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCEEEEECCCCCCCEEHH
ADYGIVGDLFQIVPALVDAFKKVK
HCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA