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The map label for this gene is sldA [H]

Identifier: 116620272

GI number: 116620272

Start: 1415034

End: 1417094

Strand: Direct

Name: sldA [H]

Synonym: Acid_1149

Alternate gene names: 116620272

Gene position: 1415034-1417094 (Clockwise)

Preceding gene: 116620271

Following gene: 116620275

Centisome position: 14.2

GC content: 64.05

Gene sequence:

>2061_bases
GTGAGGTTCGTGAAGTTCGGGCTCGCGTTGCTGGCGGCGTGCGCAATGCCGGCGGCGGATGTGCAGTGGCCCGTCAATGG
CGGGACGGACAACATTCGCTATTCGCCGCTGACGCAAATCAATCGGGAGAATGTCGGGCAGTTGAAGGAGGCGTGGAGCT
ACGACTCGCACGACGCCTTCAAGGATTCCGAGATGCAGAGCAACCCGATTGTGGTGGATGGGGTGCTGTATGCGACCACG
CCGAAGCTCCGAGTGGTGGCGCTGGATGCGGAGACTGGCCGCGAGATCTGGGCGTTCGATCCGGCGGGTGGCGCGGAGCC
GCAGAGACGCTACCGGCATCGCGGGGTGACGGTGTACCAGGAGCGCGTGTTCTTCACGCACCGGAATTTCCTGTGGGCGC
TGGACCGAAAAACGGGAAAGCCGATTCCGAGTTTCGGCAGTGAGGGACACATCGACCTGCGTGAAGGCCTGGACCGCCAA
GTGGAGAAGATGAGCGTGAGCGCGAGCAGTCCGGGGGTGATCTTCGAGGACATGATCATTCTGGGCAGCACGGTGCCGGA
GACGCTGCCCGGGTCGCCGGGGCACATCCGCGCGTTCGACGCGAAGACGGGGAAGCTGAGGTGGATTTTCCGGACGATTC
CGCGACCGGGGGAATTCGGCTACGACACGTGGTCGAAGGACAGCTACCTGGCGTCGGGCGGCGCCAATGCCTGGGCGGGG
CTGAGCGTGGACGCGAAACTCGGCATGGTGTTCGCGGCCACGGGCTCCGCGTCGTTCGATTTCTACGGTGCCAACCGCAT
CGGCGACAATTTGTTCGCGAATTGCGTGCTGGCGCTGGACGCGCGTACGGGCATGCGCGTCTGGCATTTCCAGGGGGTCC
GGCACGACACGTGGGACCTGGATTTTCCGGCAGCGCCGGGCCTGGTGACGGTGACGCGCGACGGAAAGCCGGTGGAGGCG
GTGGCGCAGATCACGAAGACCGGCTACGTGTACGTGCTGGATCGCAGGACGGGCAAGCCGCTGTTCCCCGTGAAGGAGCA
GAGCGTGCCTGCGTCGAAGTTGGACGGCGAGAAGCTTTCGCCGGTGCAGCCGTACCCAGTGAAGCCTCCGCCGTTCACGC
GGCAGGCATTCACCGAGGCGATGATCACGAATCGTACGCCGGCTGCGCACGCGGCGGTGCTGGAGCAGTTTCGCAAGCTC
GATTCGAATGGCATGTACACGCCGGAGAGTCTGCGCGGCACGATCCTCTTCCCTGGCACGGATGGCGGCGGCGAGTGGGG
AGGCGCGGCCTACGACCAGGAGAGCGGCTTGCTGTTCGTGAATTCGAACGAACAGCCGTGGATCATCCGCATGGTCACGC
ACGATACCACGTCGCTATACAAGAACAACTGCGGCGGCTGCCATGGGGACGATTTGAAGGGCGCGCCGCCGACCTTTCCC
GCGCTGGTGGATATCGGCAAACGGCGAACGCGCGAGGAACTGACGGCGATCATCCGCGAGGGCACCGGGCGCATGCCGGG
CTTTAACGACCTGGGGCGCAACGTGAACGAGATCGTCGAATTCCTGATGACCGGCAAGGACACGGGCGCGGTGGACGCGG
AGGCGGAGGCGAAGCAGCCGGGCTGGCTGAAGTATCGCAACGAAGGCTACATTCTGTTTCGCGACCCGGAGGGCTATCCG
CCGCTGACGCCGCCTTGGGGCACGCTGAATGCGATCGATCTCAACAAGGGGGAGATCAGATGGCAGATTCCGTTCGGAGA
ATATCCCGAACTCGTGGCCAAGGGAATCAGGGATACGGGCAGCGATAATTACGGCGGGCCGGTAGTGACGGCGAGCGGGC
TGGTATTCATCGGCGCCACGAGTTTCGACAAGAAATTTCGCGCGTTCGACAAGTTAACAGGCAAGCTGCTGTGGGAGACA
GTGCTGCCGGCGGCGGGCAACGCGACGCCCTCGGTGTATGAGATTCACGGACGGGAGTACGTCGTGATCGTCTGCGGCGG
CGGAAAGAACGGCGCACCATCGGGCGGGAGCATCGTGGCCTTCGCGCTGGAAGCGAAATGA

Upstream 100 bases:

>100_bases
TGTATGTGGAAGTTCCGGGAGGCAGCCACGTCGGCGTAGCTGCGCCGGCATTCCCGGGGATGCTGGACTTCTTCGCCAAG
CAGAAGAAGGACGCGGCGCA

Downstream 100 bases:

>100_bases
AGGGCGCTAATGAAAGAGGATCTCCCGCACGTGAAGGCGCAGGCGTTCCAGTTCATTCGCGTTGTGATGAAGAAGGGCGT
GATCCCAACTGATAGCAGTT

Product: pyrrolo-quinoline quinone

Products: NA

Alternate protein names: D-arabitol dehydrogenase large subunit; ARDH; D-sorbitol dehydrogenase subunit sldA; SLDH; Gluconate/polyol dehydrogenase large subunit [H]

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MRFVKFGLALLAACAMPAADVQWPVNGGTDNIRYSPLTQINRENVGQLKEAWSYDSHDAFKDSEMQSNPIVVDGVLYATT
PKLRVVALDAETGREIWAFDPAGGAEPQRRYRHRGVTVYQERVFFTHRNFLWALDRKTGKPIPSFGSEGHIDLREGLDRQ
VEKMSVSASSPGVIFEDMIILGSTVPETLPGSPGHIRAFDAKTGKLRWIFRTIPRPGEFGYDTWSKDSYLASGGANAWAG
LSVDAKLGMVFAATGSASFDFYGANRIGDNLFANCVLALDARTGMRVWHFQGVRHDTWDLDFPAAPGLVTVTRDGKPVEA
VAQITKTGYVYVLDRRTGKPLFPVKEQSVPASKLDGEKLSPVQPYPVKPPPFTRQAFTEAMITNRTPAAHAAVLEQFRKL
DSNGMYTPESLRGTILFPGTDGGGEWGGAAYDQESGLLFVNSNEQPWIIRMVTHDTTSLYKNNCGGCHGDDLKGAPPTFP
ALVDIGKRRTREELTAIIREGTGRMPGFNDLGRNVNEIVEFLMTGKDTGAVDAEAEAKQPGWLKYRNEGYILFRDPEGYP
PLTPPWGTLNAIDLNKGEIRWQIPFGEYPELVAKGIRDTGSDNYGGPVVTASGLVFIGATSFDKKFRAFDKLTGKLLWET
VLPAAGNATPSVYEIHGREYVVIVCGGGKNGAPSGGSIVAFALEAK

Sequences:

>Translated_686_residues
MRFVKFGLALLAACAMPAADVQWPVNGGTDNIRYSPLTQINRENVGQLKEAWSYDSHDAFKDSEMQSNPIVVDGVLYATT
PKLRVVALDAETGREIWAFDPAGGAEPQRRYRHRGVTVYQERVFFTHRNFLWALDRKTGKPIPSFGSEGHIDLREGLDRQ
VEKMSVSASSPGVIFEDMIILGSTVPETLPGSPGHIRAFDAKTGKLRWIFRTIPRPGEFGYDTWSKDSYLASGGANAWAG
LSVDAKLGMVFAATGSASFDFYGANRIGDNLFANCVLALDARTGMRVWHFQGVRHDTWDLDFPAAPGLVTVTRDGKPVEA
VAQITKTGYVYVLDRRTGKPLFPVKEQSVPASKLDGEKLSPVQPYPVKPPPFTRQAFTEAMITNRTPAAHAAVLEQFRKL
DSNGMYTPESLRGTILFPGTDGGGEWGGAAYDQESGLLFVNSNEQPWIIRMVTHDTTSLYKNNCGGCHGDDLKGAPPTFP
ALVDIGKRRTREELTAIIREGTGRMPGFNDLGRNVNEIVEFLMTGKDTGAVDAEAEAKQPGWLKYRNEGYILFRDPEGYP
PLTPPWGTLNAIDLNKGEIRWQIPFGEYPELVAKGIRDTGSDNYGGPVVTASGLVFIGATSFDKKFRAFDKLTGKLLWET
VLPAAGNATPSVYEIHGREYVVIVCGGGKNGAPSGGSIVAFALEAK
>Mature_686_residues
MRFVKFGLALLAACAMPAADVQWPVNGGTDNIRYSPLTQINRENVGQLKEAWSYDSHDAFKDSEMQSNPIVVDGVLYATT
PKLRVVALDAETGREIWAFDPAGGAEPQRRYRHRGVTVYQERVFFTHRNFLWALDRKTGKPIPSFGSEGHIDLREGLDRQ
VEKMSVSASSPGVIFEDMIILGSTVPETLPGSPGHIRAFDAKTGKLRWIFRTIPRPGEFGYDTWSKDSYLASGGANAWAG
LSVDAKLGMVFAATGSASFDFYGANRIGDNLFANCVLALDARTGMRVWHFQGVRHDTWDLDFPAAPGLVTVTRDGKPVEA
VAQITKTGYVYVLDRRTGKPLFPVKEQSVPASKLDGEKLSPVQPYPVKPPPFTRQAFTEAMITNRTPAAHAAVLEQFRKL
DSNGMYTPESLRGTILFPGTDGGGEWGGAAYDQESGLLFVNSNEQPWIIRMVTHDTTSLYKNNCGGCHGDDLKGAPPTFP
ALVDIGKRRTREELTAIIREGTGRMPGFNDLGRNVNEIVEFLMTGKDTGAVDAEAEAKQPGWLKYRNEGYILFRDPEGYP
PLTPPWGTLNAIDLNKGEIRWQIPFGEYPELVAKGIRDTGSDNYGGPVVTASGLVFIGATSFDKKFRAFDKLTGKLLWET
VLPAAGNATPSVYEIHGREYVVIVCGGGKNGAPSGGSIVAFALEAK

Specific function: Catalyzes the oxidation of glycerol to glycerone. Also acts, more slowly, on a number of other polyols including D- sorbitol, D-arabinitol, D-mannitol, meso-erythritol, adonitol and propylene glycol [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=476, Percent_Identity=29.6218487394958, Blast_Score=211, Evalue=9e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.99.22 [H]

Molecular weight: Translated: 74998; Mature: 74998

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVKFGLALLAACAMPAADVQWPVNGGTDNIRYSPLTQINRENVGQLKEAWSYDSHDAF
CCHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEECCHHHCCHHHHHHHHHHHCCCCCCCC
KDSEMQSNPIVVDGVLYATTPKLRVVALDAETGREIWAFDPAGGAEPQRRYRHRGVTVYQ
CCCCCCCCCEEEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHCCCEEEE
ERVFFTHRNFLWALDRKTGKPIPSFGSEGHIDLREGLDRQVEKMSVSASSPGVIFEDMII
EEEEEEECCEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCEEEHHHHE
LGSTVPETLPGSPGHIRAFDAKTGKLRWIFRTIPRPGEFGYDTWSKDSYLASGGANAWAG
ECCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCEEC
LSVDAKLGMVFAATGSASFDFYGANRIGDNLFANCVLALDARTGMRVWHFQGVRHDTWDL
EEECCEEEEEEEECCCCCEEECCCHHCCCHHHEEEEEEEECCCCCEEEEECCCCCCCCCC
DFPAAPGLVTVTRDGKPVEAVAQITKTGYVYVLDRRTGKPLFPVKEQSVPASKLDGEKLS
CCCCCCCEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCC
PVQPYPVKPPPFTRQAFTEAMITNRTPAAHAAVLEQFRKLDSNGMYTPESLRGTILFPGT
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCEEEEECCC
DGGGEWGGAAYDQESGLLFVNSNEQPWIIRMVTHDTTSLYKNNCGGCHGDDLKGAPPTFP
CCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCH
ALVDIGKRRTREELTAIIREGTGRMPGFNDLGRNVNEIVEFLMTGKDTGAVDAEAEAKQP
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
GWLKYRNEGYILFRDPEGYPPLTPPWGTLNAIDLNKGEIRWQIPFGEYPELVAKGIRDTG
CCEEECCCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHCCC
SDNYGGPVVTASGLVFIGATSFDKKFRAFDKLTGKLLWETVLPAAGNATPSVYEIHGREY
CCCCCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEE
VVIVCGGGKNGAPSGGSIVAFALEAK
EEEEECCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MRFVKFGLALLAACAMPAADVQWPVNGGTDNIRYSPLTQINRENVGQLKEAWSYDSHDAF
CCHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEECCHHHCCHHHHHHHHHHHCCCCCCCC
KDSEMQSNPIVVDGVLYATTPKLRVVALDAETGREIWAFDPAGGAEPQRRYRHRGVTVYQ
CCCCCCCCCEEEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHCCCEEEE
ERVFFTHRNFLWALDRKTGKPIPSFGSEGHIDLREGLDRQVEKMSVSASSPGVIFEDMII
EEEEEEECCEEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCCCEEEHHHHE
LGSTVPETLPGSPGHIRAFDAKTGKLRWIFRTIPRPGEFGYDTWSKDSYLASGGANAWAG
ECCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCCCCEEC
LSVDAKLGMVFAATGSASFDFYGANRIGDNLFANCVLALDARTGMRVWHFQGVRHDTWDL
EEECCEEEEEEEECCCCCEEECCCHHCCCHHHEEEEEEEECCCCCEEEEECCCCCCCCCC
DFPAAPGLVTVTRDGKPVEAVAQITKTGYVYVLDRRTGKPLFPVKEQSVPASKLDGEKLS
CCCCCCCEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCC
PVQPYPVKPPPFTRQAFTEAMITNRTPAAHAAVLEQFRKLDSNGMYTPESLRGTILFPGT
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCEEEEECCC
DGGGEWGGAAYDQESGLLFVNSNEQPWIIRMVTHDTTSLYKNNCGGCHGDDLKGAPPTFP
CCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCH
ALVDIGKRRTREELTAIIREGTGRMPGFNDLGRNVNEIVEFLMTGKDTGAVDAEAEAKQP
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
GWLKYRNEGYILFRDPEGYPPLTPPWGTLNAIDLNKGEIRWQIPFGEYPELVAKGIRDTG
CCEEECCCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHCCC
SDNYGGPVVTASGLVFIGATSFDKKFRAFDKLTGKLLWETVLPAAGNATPSVYEIHGREY
CCCCCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEE
VVIVCGGGKNGAPSGGSIVAFALEAK
EEEEECCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA