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The map label for this gene is rprX [H]

Identifier: 116620225

GI number: 116620225

Start: 1354176

End: 1355846

Strand: Reverse

Name: rprX [H]

Synonym: Acid_1102

Alternate gene names: 116620225

Gene position: 1355846-1354176 (Counterclockwise)

Preceding gene: 116620227

Following gene: 116620224

Centisome position: 13.61

GC content: 68.1

Gene sequence:

>1671_bases
TTGAAGTGGCCGGAAAAGCTCGTGGCGGGCGTGGTGGCGCTGATCGCGGTGCTGGCGGCGTTGCAATATCGCAGCATCGT
GCAGGTAAGCCGGGCGGAGCGGGCGCGGCTGGCGGACGAACTACAGGCATCGCTGGTGCGGTTCACGCAGGAGTTCGACG
GCGAGATCAATCGGGTCTTACTAGCGGCGAACGGCGCGGGGCCGGGGCCGCCGGATCGGCGTTTGGAGGAGCCGGCGGCG
CGGATCGCGGGATGGCAGGCGGCGACACCGTATCGCAACCTGGTGCGCGCGTTCTATCGTTTCGACGGTGGGCAGCTATA
TCGCTTCGATGCCGAGAAGGAGCGCTTTGAGGCTGCGGACGCGCCCCGGTGGCTGGCCGGACTGCCGGCGATGGGACCGC
CGGTGCAGGCGATCTCCGGGGGTGGCGGGATCGCGATCCTGGTGCGGAATGTGCGGCCGCGCGGCTTTGGTCGTGGCGGA
CCTCCGCCGCCTCAGGAGGAGGCGGAGCGCGGGTGGTCGGTAATCGAACTCAACCTGGATTTCGTTTCGCATGATATGTT
GCCGCGGCTGGCGGCGAAGCATTTCACGCCGGATTACATGGTGCAGGTGGCGTCGCGGGACGAGCCGCGGCAGGTTTTCT
ACTCCTCGTCGGCAGATGCCGGCGCGGGCACGCCCGATGCTGTGACGGGGCTGTTCGAATTGCGGTTTGAAGGCGGCGGA
ATGCCTGGTTTTGGCGGCGGACGGCGCGGAGGCGGCGGGCCGTTCCTGCGGCAGCCGCCGTTTCCGGGGCAGAATCCCGA
TCCAGGGCGACGCGGGATATGGGAGGTGCGGGTGCGGCACAACGCGGGATCACTGGAGGCGGCCGCCTCACAGACGCGGA
ATCGCGATCTGGCGGTGAGCGCGGTGGTGCTGTTACTGTTGCTGCTGACCGTGGCTGCGCTGGCGGTGGTGACGCGCCGC
GCGCAACGGCTCGCGGCGCTGCAGATGGAGTTTGTCTCGGGAGTGAGCCACGAGTTGCGGACTCCGCTGGCGGTGATCGG
CAGCGCGGCCGATAACCTGGCGGACGGCGTGGTGGCGAGCGATGCTCAGGTGCGGCGCTACGGCGCACTGATCCGGGGCG
AAGGGCGGCGGCTGACGGAGATGGTCGAGCAGGTGCTCAGCTATGCGTCGCTGCAATCGGGAAAGAAGCGCGTGGAACGC
CGGGCGGTGGAGATCGCGGGGGTAATCGACGGGGCAATTGAGGCGTGCGCGGGCCAGATCGAGGAAACACGTTGCGCGGT
GGAGCGGGAGATTCCGGAGGGATTACCGAGGGTGGCGGCGGACGAGGCGTCGCTGATCCACTGCATCGCGAACCTGCTCG
GGAATGCGCTGAAGTATGGCGAGCCGGGGCACCACGTGCGGATCGTGGCGGCGACACAGCCGGGCAGCGTCGAGATCCGC
GTGAGCGATACCGGCTTTGGGATCGACGCTGAGGATCTGCCGCACATTTTCGACGCCTTCTACCGCGGACGCAGCGTGGC
TGAGGGGACGATTCGCGGCACCGGCCTCGGGCTGAGCCTGGTGCGGCGGATCGTGGAGGCGCATGACGGAACAGTGAACG
TGGAGAGCACGGCTGGTATGGGAAGCTGTTTCACGCTGCGGCTGCCGGTTGCGGCCGGGGAGGTTACCTGA

Upstream 100 bases:

>100_bases
CCATTTCCCGGAGAAGGTTAGTTAAACATCTGGAAAATAAGGTTTTACGTTCTTAACATTGGAGTGCTCGGGGAGCGTCT
CATGGTAAGCTGGCAATGCT

Downstream 100 bases:

>100_bases
TGACGCCGCGCATTTTGCTGGCGGAAGACGATCCCGGGTTGGTTCTGACGCTAACCGACCGGTTGCAGAATGAGGGCTAC
GCGGTGGAATCTCGACAGGA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MKWPEKLVAGVVALIAVLAALQYRSIVQVSRAERARLADELQASLVRFTQEFDGEINRVLLAANGAGPGPPDRRLEEPAA
RIAGWQAATPYRNLVRAFYRFDGGQLYRFDAEKERFEAADAPRWLAGLPAMGPPVQAISGGGGIAILVRNVRPRGFGRGG
PPPPQEEAERGWSVIELNLDFVSHDMLPRLAAKHFTPDYMVQVASRDEPRQVFYSSSADAGAGTPDAVTGLFELRFEGGG
MPGFGGGRRGGGGPFLRQPPFPGQNPDPGRRGIWEVRVRHNAGSLEAAASQTRNRDLAVSAVVLLLLLLTVAALAVVTRR
AQRLAALQMEFVSGVSHELRTPLAVIGSAADNLADGVVASDAQVRRYGALIRGEGRRLTEMVEQVLSYASLQSGKKRVER
RAVEIAGVIDGAIEACAGQIEETRCAVEREIPEGLPRVAADEASLIHCIANLLGNALKYGEPGHHVRIVAATQPGSVEIR
VSDTGFGIDAEDLPHIFDAFYRGRSVAEGTIRGTGLGLSLVRRIVEAHDGTVNVESTAGMGSCFTLRLPVAAGEVT

Sequences:

>Translated_556_residues
MKWPEKLVAGVVALIAVLAALQYRSIVQVSRAERARLADELQASLVRFTQEFDGEINRVLLAANGAGPGPPDRRLEEPAA
RIAGWQAATPYRNLVRAFYRFDGGQLYRFDAEKERFEAADAPRWLAGLPAMGPPVQAISGGGGIAILVRNVRPRGFGRGG
PPPPQEEAERGWSVIELNLDFVSHDMLPRLAAKHFTPDYMVQVASRDEPRQVFYSSSADAGAGTPDAVTGLFELRFEGGG
MPGFGGGRRGGGGPFLRQPPFPGQNPDPGRRGIWEVRVRHNAGSLEAAASQTRNRDLAVSAVVLLLLLLTVAALAVVTRR
AQRLAALQMEFVSGVSHELRTPLAVIGSAADNLADGVVASDAQVRRYGALIRGEGRRLTEMVEQVLSYASLQSGKKRVER
RAVEIAGVIDGAIEACAGQIEETRCAVEREIPEGLPRVAADEASLIHCIANLLGNALKYGEPGHHVRIVAATQPGSVEIR
VSDTGFGIDAEDLPHIFDAFYRGRSVAEGTIRGTGLGLSLVRRIVEAHDGTVNVESTAGMGSCFTLRLPVAAGEVT
>Mature_556_residues
MKWPEKLVAGVVALIAVLAALQYRSIVQVSRAERARLADELQASLVRFTQEFDGEINRVLLAANGAGPGPPDRRLEEPAA
RIAGWQAATPYRNLVRAFYRFDGGQLYRFDAEKERFEAADAPRWLAGLPAMGPPVQAISGGGGIAILVRNVRPRGFGRGG
PPPPQEEAERGWSVIELNLDFVSHDMLPRLAAKHFTPDYMVQVASRDEPRQVFYSSSADAGAGTPDAVTGLFELRFEGGG
MPGFGGGRRGGGGPFLRQPPFPGQNPDPGRRGIWEVRVRHNAGSLEAAASQTRNRDLAVSAVVLLLLLLTVAALAVVTRR
AQRLAALQMEFVSGVSHELRTPLAVIGSAADNLADGVVASDAQVRRYGALIRGEGRRLTEMVEQVLSYASLQSGKKRVER
RAVEIAGVIDGAIEACAGQIEETRCAVEREIPEGLPRVAADEASLIHCIANLLGNALKYGEPGHHVRIVAATQPGSVEIR
VSDTGFGIDAEDLPHIFDAFYRGRSVAEGTIRGTGLGLSLVRRIVEAHDGTVNVESTAGMGSCFTLRLPVAAGEVT

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=281, Percent_Identity=27.7580071174377, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=27.1604938271605, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=31.1965811965812, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=27.8008298755187, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=26.4957264957265, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI87081816, Length=223, Percent_Identity=30.9417040358744, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=26.3157894736842, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=232, Percent_Identity=28.8793103448276, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789808, Length=235, Percent_Identity=30.2127659574468, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=23.015873015873, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790861, Length=219, Percent_Identity=30.1369863013699, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=25.5411255411255, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=24.2290748898678, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59498; Mature: 59498

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWPEKLVAGVVALIAVLAALQYRSIVQVSRAERARLADELQASLVRFTQEFDGEINRVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LAANGAGPGPPDRRLEEPAARIAGWQAATPYRNLVRAFYRFDGGQLYRFDAEKERFEAAD
EEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHCC
APRWLAGLPAMGPPVQAISGGGGIAILVRNVRPRGFGRGGPPPPQEEAERGWSVIELNLD
CCHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHCCCEEEEEEHH
FVSHDMLPRLAAKHFTPDYMVQVASRDEPRQVFYSSSADAGAGTPDAVTGLFELRFEGGG
HHHHHHHHHHHHHHCCHHHHHEECCCCCCHHHEECCCCCCCCCCHHHHHHEEEEEECCCC
MPGFGGGRRGGGGPFLRQPPFPGQNPDPGRRGIWEVRVRHNAGSLEAAASQTRNRDLAVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHH
AVVLLLLLLTVAALAVVTRRAQRLAALQMEFVSGVSHELRTPLAVIGSAADNLADGVVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCCCC
DAQVRRYGALIRGEGRRLTEMVEQVLSYASLQSGKKRVERRAVEIAGVIDGAIEACAGQI
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EETRCAVEREIPEGLPRVAADEASLIHCIANLLGNALKYGEPGHHVRIVAATQPGSVEIR
HHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEE
VSDTGFGIDAEDLPHIFDAFYRGRSVAEGTIRGTGLGLSLVRRIVEAHDGTVNVESTAGM
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCC
GSCFTLRLPVAAGEVT
CCEEEEEEECCCCCCC
>Mature Secondary Structure
MKWPEKLVAGVVALIAVLAALQYRSIVQVSRAERARLADELQASLVRFTQEFDGEINRVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LAANGAGPGPPDRRLEEPAARIAGWQAATPYRNLVRAFYRFDGGQLYRFDAEKERFEAAD
EEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHCC
APRWLAGLPAMGPPVQAISGGGGIAILVRNVRPRGFGRGGPPPPQEEAERGWSVIELNLD
CCHHHHCCCCCCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHCCCEEEEEEHH
FVSHDMLPRLAAKHFTPDYMVQVASRDEPRQVFYSSSADAGAGTPDAVTGLFELRFEGGG
HHHHHHHHHHHHHHCCHHHHHEECCCCCCHHHEECCCCCCCCCCHHHHHHEEEEEECCCC
MPGFGGGRRGGGGPFLRQPPFPGQNPDPGRRGIWEVRVRHNAGSLEAAASQTRNRDLAVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHH
AVVLLLLLLTVAALAVVTRRAQRLAALQMEFVSGVSHELRTPLAVIGSAADNLADGVVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHCCCCCC
DAQVRRYGALIRGEGRRLTEMVEQVLSYASLQSGKKRVERRAVEIAGVIDGAIEACAGQI
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EETRCAVEREIPEGLPRVAADEASLIHCIANLLGNALKYGEPGHHVRIVAATQPGSVEIR
HHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEE
VSDTGFGIDAEDLPHIFDAFYRGRSVAEGTIRGTGLGLSLVRRIVEAHDGTVNVESTAGM
ECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCC
GSCFTLRLPVAAGEVT
CCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]