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The map label for this gene is aroF [H]

Identifier: 116620192

GI number: 116620192

Start: 1317680

End: 1318717

Strand: Direct

Name: aroF [H]

Synonym: Acid_1065

Alternate gene names: 116620192

Gene position: 1317680-1318717 (Clockwise)

Preceding gene: 116620191

Following gene: 116620193

Centisome position: 13.22

GC content: 62.62

Gene sequence:

>1038_bases
ATGATTATTTCGATGCGACCGCACGCGACCCGGGAAGAAATTGACCACGTTTGCGACCGGATTGCGGAATTCGGATATAA
GGTGCACTCCATCGAAGGCGAGGAGCGCGTCGTGATCGGGGTTGTCGGCGTCGGCGACGTGACGGCGTGTTTGGAATCGC
TGGAGGCTACGCCTGGCGTGGAGCGCGCGATGCGGATCTCCGCCCCGTACAAATTCGTCAGCAAGGAGTTCCGCAAGGGA
CGGTCGGTGGTCCGGGTGAACGGCACCGAAATCGGCGGCGACGAGTTCGTGATGATGGCGGGGCCGTGCTCAGTGGAAAG
CGAAAAGCAGATCATGGAGACGGCCGAGAGCGTGGCCGCGGCGGGAGCCAAGATCCTTCGCGGCGGCGCATTCAAGCCGC
GAACGTCGCCCTACGATTTCCAGGGACTGGAACTGGAAGGCCTCAAGCTGCTGCGCAAGGCGAAAGAACGGACGGGGCTG
GGCATCATCACCGAAATCATGAGCGACCGCGATGTGGAACTGGTGGCCGAGTATGCCGATTGCATGCAGGTCGGCGCGCG
CAATATGCAGAATTTCGCGCTCTTGAAATCGCTGGGCGGCTGCGGACGGCCGGTGCTCCTGAAGCGCGGCATGAGCTCGA
CGATCAAGGAACTGCTGATGTCGGCGGAGTATATTGTGGCGCACGGCAACCCCAACGTGATTCTCTGCGAGCGCGGCATC
CGGACGTTCGAGACGGCGACGCGCAACACCTGCGATATCGCGGCCGTGCCGGTGCTGAATGAGCTGACGCACCTGCCGGT
GGTCCTGGATCCGAGCCACGCGACGGGCAAGCGCAGCCTGATTCCGGCGCTCTCTCGGGCGGGGGTTGCGATTGGCGCGG
ACGGGCTGATTATCGAAGTGCATCCCTGCCCGGAAAAGGCGGTCAGCGATGGAGCTCAATCGCTTACGCTGCCGGCGTTC
CAGGCGATGATGGACGAGCTTCAACCCTACATTCGTCTTTGGAGTGAAGCGCGCACCAGCGACCTTGCGGCTGTGTGA

Upstream 100 bases:

>100_bases
GCGCCGTAGGTATACACCGCCTGTTAGTGGTGGTATTAAGCTATAGTCATACATTGGGTTAACTCCACTGCCGCAAGGCG
AATAGTGTATACTGCCAAGT

Downstream 100 bases:

>100_bases
TACTCGATTCGTGACCCCTAAATTCCGAGCGTGGCTGCTGGTGGTGATCGTCTCCGCGCTCTGTGGCCTCTCGCTTGGCG
GCGTGATCTGGTACCGCTCG

Product: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MIISMRPHATREEIDHVCDRIAEFGYKVHSIEGEERVVIGVVGVGDVTACLESLEATPGVERAMRISAPYKFVSKEFRKG
RSVVRVNGTEIGGDEFVMMAGPCSVESEKQIMETAESVAAAGAKILRGGAFKPRTSPYDFQGLELEGLKLLRKAKERTGL
GIITEIMSDRDVELVAEYADCMQVGARNMQNFALLKSLGGCGRPVLLKRGMSSTIKELLMSAEYIVAHGNPNVILCERGI
RTFETATRNTCDIAAVPVLNELTHLPVVLDPSHATGKRSLIPALSRAGVAIGADGLIIEVHPCPEKAVSDGAQSLTLPAF
QAMMDELQPYIRLWSEARTSDLAAV

Sequences:

>Translated_345_residues
MIISMRPHATREEIDHVCDRIAEFGYKVHSIEGEERVVIGVVGVGDVTACLESLEATPGVERAMRISAPYKFVSKEFRKG
RSVVRVNGTEIGGDEFVMMAGPCSVESEKQIMETAESVAAAGAKILRGGAFKPRTSPYDFQGLELEGLKLLRKAKERTGL
GIITEIMSDRDVELVAEYADCMQVGARNMQNFALLKSLGGCGRPVLLKRGMSSTIKELLMSAEYIVAHGNPNVILCERGI
RTFETATRNTCDIAAVPVLNELTHLPVVLDPSHATGKRSLIPALSRAGVAIGADGLIIEVHPCPEKAVSDGAQSLTLPAF
QAMMDELQPYIRLWSEARTSDLAAV
>Mature_345_residues
MIISMRPHATREEIDHVCDRIAEFGYKVHSIEGEERVVIGVVGVGDVTACLESLEATPGVERAMRISAPYKFVSKEFRKG
RSVVRVNGTEIGGDEFVMMAGPCSVESEKQIMETAESVAAAGAKILRGGAFKPRTSPYDFQGLELEGLKLLRKAKERTGL
GIITEIMSDRDVELVAEYADCMQVGARNMQNFALLKSLGGCGRPVLLKRGMSSTIKELLMSAEYIVAHGNPNVILCERGI
RTFETATRNTCDIAAVPVLNELTHLPVVLDPSHATGKRSLIPALSRAGVAIGADGLIIEVHPCPEKAVSDGAQSLTLPAF
QAMMDELQPYIRLWSEARTSDLAAV

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=268, Percent_Identity=25.3731343283582, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 37339; Mature: 37339

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISMRPHATREEIDHVCDRIAEFGYKVHSIEGEERVVIGVVGVGDVTACLESLEATPGV
CEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCH
ERAMRISAPYKFVSKEFRKGRSVVRVNGTEIGGDEFVMMAGPCSVESEKQIMETAESVAA
HHHHHHCCCHHHHHHHHHCCCCEEEECCCEECCCCEEEEECCCCCCHHHHHHHHHHHHHH
AGAKILRGGAFKPRTSPYDFQGLELEGLKLLRKAKERTGLGIITEIMSDRDVELVAEYAD
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHH
CMQVGARNMQNFALLKSLGGCGRPVLLKRGMSSTIKELLMSAEYIVAHGNPNVILCERGI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCEEEEECCCCEEEECCCC
RTFETATRNTCDIAAVPVLNELTHLPVVLDPSHATGKRSLIPALSRAGVAIGADGLIIEV
HHHHHHCCCCCCEEHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCEEECCCCEEEEE
HPCPEKAVSDGAQSLTLPAFQAMMDELQPYIRLWSEARTSDLAAV
ECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MIISMRPHATREEIDHVCDRIAEFGYKVHSIEGEERVVIGVVGVGDVTACLESLEATPGV
CEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCH
ERAMRISAPYKFVSKEFRKGRSVVRVNGTEIGGDEFVMMAGPCSVESEKQIMETAESVAA
HHHHHHCCCHHHHHHHHHCCCCEEEECCCEECCCCEEEEECCCCCCHHHHHHHHHHHHHH
AGAKILRGGAFKPRTSPYDFQGLELEGLKLLRKAKERTGLGIITEIMSDRDVELVAEYAD
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHH
CMQVGARNMQNFALLKSLGGCGRPVLLKRGMSSTIKELLMSAEYIVAHGNPNVILCERGI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCEEEEECCCCEEEECCCC
RTFETATRNTCDIAAVPVLNELTHLPVVLDPSHATGKRSLIPALSRAGVAIGADGLIIEV
HHHHHHCCCCCCEEHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCEEECCCCEEEEE
HPCPEKAVSDGAQSLTLPAFQAMMDELQPYIRLWSEARTSDLAAV
ECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]